Characterization of the effects of gabapentin and 3-isobutyl-γ- aminobutyric acid on substance P-induced thermal hyperalgesia

Anesthesiology

Volumn 88, Issue 1, 1998, Pages 196-205

  Partridge, Brett J ^c   Chaplan, Sandra R ^c   Sakamoto, Eiji ^a   Yaksh, Tony L ^b  

^a KYUSHU DENTAL COLLEGE   (Japan)

^b University of California   (United States)

^c NONE

Author keywords

D serine; GABA; Gabapentinoid; Intrathecal; Neurontin; NMDA

Indexed keywords

4 AMINOBUTYRIC ACID DERIVATIVE; GABAPENTIN; N METHYL DEXTRO ASPARTIC ACID; PREGABALIN; SERINE; SUBSTANCE P; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BINDING SITE; DOSE RESPONSE; DRUG MECHANISM; DRUG RECEPTOR BINDING; GABAERGIC TRANSMISSION; HYPERALGESIA; INTRAPERITONEAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; MALE; MODEL; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SPINAL CORD;

ACETIC ACIDS; AMINES; ANALGESICS; ANIMALS; BEHAVIOR, ANIMAL; CYCLOHEXANECARBOXYLIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-AMINOBUTYRIC ACID; HYPERALGESIA; MALE; N-METHYLASPARTATE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA; RECEPTORS, GLUTAMATE; SERINE; STEREOISOMERISM; SUBSTANCE P;

EID: 0031963052     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199801000-00028     Document Type: Article

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