Transient Phosphatidylinositol 3-Kinase Inhibition Protects Immature Primary Cortical Neurons from Oxidative Toxicity via Suppression of Extracellular Signal-regulated Kinase Activation

Journal of Biological Chemistry

Volumn 279, Issue 12, 2004, Pages 11206-11213

  Levinthal, David J ^a   DeFranco, Donald B ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; NEUROLOGY; SYNTHESIS (CHEMICAL); TOXICITY;

NEURONS; OXIDATIVE STRESSES;

ENZYMES;

ANTIPORTER; CYSTINE; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FETUS; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CEREBRAL CORTEX; CHROMONES; ENZYME ACTIVATION; ENZYME INHIBITORS; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; NEURONS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 1642442504     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M314261200     Document Type: Article

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