Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase

Journal of Biological Chemistry

Volumn 277, Issue 41, 2002, Pages 38021-38028

  Conus, Nelly Marmy ^a   Hannan, Katherine M ^a   Cristiano, Briony E ^a   Hemmings, Brian A ^a   Pearson, Richard B ^a,b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; ENZYME INHIBITION; HORMONES; PHYSIOLOGY;

PHOSPHORYLATION;

ENZYMES;

PERVANADATE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SERINE; SOMATOMEDIN C; THREONINE; TYROSINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HYDROPHOBICITY; MALIGNANT TRANSFORMATION; NONHUMAN; OVARY CARCINOMA; PLEIOTROPY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CARCINOMA; COS CELLS; CULTURE MEDIA, SERUM-FREE; ENZYME INHIBITORS; FEMALE; GENES, REPORTER; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MUTAGENESIS, SITE-DIRECTED; OVARIAN NEOPLASMS; PEPTIDE MAPPING; PHOSPHOPEPTIDES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED; TYROSINE; VANADATES;

ANIMALIA;

EID: 0037064005     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M203387200     Document Type: Article

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