Tobacco Carcinogen-Induced Cellular Transformation Increases Activation of the Phosphatidylinositol 3′-Kinase/Akt Pathway in Vitro and in Vivo

Cancer Research

Volumn 64, Issue 2, 2004, Pages 446-451

  West, Kip A ^a   Linnoila, Ilona R ^a   Belinsky, Steven A ^b   Harris, Curtis C ^a   Dennis, Phillip A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; CARCINOGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAPAMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL IMMORTALIZATION; CELL SURVIVAL; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG CARCINOGENESIS; MOUSE; NONHUMAN; PHENOTYPE; PRECANCER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TOBACCO;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CARCINOGENS; CELL LINE; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; ENZYME ACTIVATION; HUMANS; LUNG; LUNG NEOPLASMS; MICE; PRECANCEROUS CONDITIONS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RESPIRATORY MUCOSA; TOBACCO;

EID: 1642434133     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3241     Document Type: Article

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