K-ras Gene Mutation Enhances Motility of Immortalized Airway Cells and Lung Adenocarcinoma Cells via Akt Activation: Possible Contribution to Non-Invasive Expansion of Lung Adenocarcinoma

American Journal of Pathology

Volumn 164, Issue 1, 2004, Pages 91-100

  Okudela, Koji ^a   Hayashi, Hiroyuki ^b   Ito, Takaaki ^a   Yazawa, Takuya ^a   Suzuki, Takehisa ^a   Nakane, Yuko ^a   Sato, Hanako ^a   Ishi, Haruhiko ^a   KeQin, Xin ^a   Masuda, Akira ^c   Takahashi, Takashi ^c   Kitamura, Hitoshi ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b KANAGAWA CANCER CENTER   (Japan)

^c AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

K RAS PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; AKT1 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE;

AIRWAY; ARTICLE; CANCER GROWTH; CANCER INVASION; CELL GROWTH; CELL MOTILITY; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; EPITHELIUM CELL; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; METASTASIS; ONCOGENE K RAS; POINT MUTATION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN PROTEIN INTERACTION; RESPIRATORY EPITHELIUM; WILD TYPE; ADENOCARCINOMA; ANIMAL; CELL LINE; CELL MOTION; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; IMMUNOHISTOCHEMISTRY; LUNG TUMOR; METABOLISM; MUTATION; ONCOGENE RAS; PATHOLOGY; PHYSIOLOGY; WESTERN BLOTTING;

ADENOCARCINOMA; ANIMALS; BLOTTING, WESTERN; CELL LINE, TRANSFORMED; CELL MOVEMENT; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MUTATION; NEOPLASM INVASIVENESS; PROGNOSIS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TRANSFECTION;

EID: 1542469696     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63100-8     Document Type: Article

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