Characterization of two T. gondii CK1 isoforms

Molecular and Biochemical Parasitology

Volumn 141, Issue 1, 2005, Pages 15-27

  Donald, Robert G K ^a   Zhong, Tanya ^a   Meijer, Laurent ^b   Liberator, Paul A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b STATION BIOLOGIQUE   (France)

Author keywords

Casein kinase 1; Cyclin dependent protein kinase; Purvalanol; Toxoplasma

Indexed keywords

AMINOPURVALANOL A; ANTIPARASITIC AGENT; CASEIN KINASE I; CYCLIN DEPENDENT KINASE INHIBITOR; EPITOPE; POLYPEPTIDE; PROTEIN KINASE; PURVALANOL B; RECOMBINANT ENZYME; TOXOPLASMA GONDII CASEIN KINASE 1 ALPHA; TOXOPLASMA GONDII CASEIN KINASE 1 BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL STRAIN; BIOCHEMISTRY; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CHROMATOGRAPHY; DATA BASE; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE DELETION; GENE IDENTIFICATION; GENE MAPPING; HOST PARASITE INTERACTION; ION EXCHANGE CHROMATOGRAPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE CONTROL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEROLOGY; TOXOPLASMA GONDII; TRYPANOSOMA CRUZI;

EID: 16244374960     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2005.01.011     Document Type: Article

References (67)

1. P. Cohen Protein kinases - the major drug targets of the twenty-first century? Nature Rev Drug Discovery 1 2002 309 315
2. A.L. Hopkins, and C.R. Groom The druggable genome Nature Rev Drug Discovery 1 2002 727 730
3. R. Sridhar, O. Hanson-Painton, and D.R. Cooper Protein kinases as therapeutic targets Pharm Res 17 2000 1345 1353
4. D. Fabbro, S. Ruetz, and E. Buchdunger Protein kinases as targets for anticancer agents: from inhibitors to useful drugs Pharmacol Ther 93 2-3 2002 79 98
5. R. Kurzrock, H.M. Kantarjian, B.J. Druker, and M. Talpaz Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics Ann Intern Med 138 10 2003 819 830
6. C. Doerig, L. Meijer, and J.C. Mottram Protein kinases as drug targets in parasitic protozoa Trends Parasitol 18 8 2002 366 371
7. C. Doerig Protein kinases as targets for anti-parasitic chemotherapy Biochim Biophys Acta 1697 1-2 2004 155 168
8. A.M. Gurnett, P.A. Liberator, and P.M. Dulski Purification and molecular characterization of cGMP dependent protein kinase from apicomplexan parasites: a novel chemotherapeutic target J Biol Chem 277 2002 15913 15922
9. R.G.K. Donald, J. Allocco, and S.B. Singh Toxoplasma gondii cGMP-dependent kinase: chemotherapeutic targeting of an essential parasite protein kinase. Eukaryotic Cell 1 2002 317 328
10. B. Nare, J. Allocco, P.A. Liberator, and R.G.K. Donald Evaluation of a cGMP-dependent protein kinase inhibitor in the treatment of murine toxoplasmosis: gamma-interferon is required for efficacy Antimicrob Agents Chemother 46 2002 300 307
11. M. Knockaert, N. Gray, and E. Damiens Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilized inhibitors Chem Biol 7 2000 411 422
12. Y.T. Chang, N.G. Gray, and G.R. Rosania Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors Chem Biol 6 1999 361 375
13. N.S. Gray, L. Wodicka, and A.M. Thunnissen Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors Science 281 5376 1998 533 538
14. L. Meijer, and E. Raymond Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials Accounts Chem Res 36 2003 417 425
15. S.D. Gross, and R.A. Anderson Casein kinase I: spatial organization and positioning of a multifunctional protein kinase family Cell Signal 10 10 1998 699 711
16. E. Vielhaber, and D.M. Virshup Casein kinase I: from obscurity to center stage IUBMB Life 51 2001 73 78
17. P.C. Wang, A. Vancura, T.G. Mitcheson, and J. Kuret Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1 Mol Biol Cell 3 1992 275 286
18. X. Wang, M.F. Hoekstra, and A.J. DeMaggio Prenylated isoforms of yeast casein kinase I, including the novel Yck3p, suppress the gcs1 blockage of cell proliferation from stationary phase Mol Cell Biol 16 10 1996 5375 5385 Oct
19. L.C. Robinson, E.J. Hubbard, and P.R. Graves Yeast casein kinase I homologues: an essential gene pair Proc Natl Acad Sci U S A 89 1 1992 28 32
20. G. Moreno-Bueno, C. Cales, M.M. Behrens, and M. Fernandez-Renart Isolation and characterization of casein kinase I from Dictyostelium discoideum Biochem J 349 2000 527 537
21. S. Barik, R.E. Taylor, and D. Chakrabarti Identification, cloning, and mutational analysis of the casein kinase 1 cDNA of the malaria parasite, Plasmodium falciparum. Stage-specific expression of the gene J Biol Chem 272 1997 26132 26138
22. L.L. Vieira, N. Sacerdoti-Sierra, and C.L. Jaffe Effect of pH and temperature on protein kinase release by Leishmania donovani Int J Parasitol 32 2002 1085 1093
23. N. Sacerdoti-Sierra, and C.L. Jaffe Release of ecto-protein kinases by the protozoan parasite Leishmania major J Biol Chem 272 49 1997 30760 30765
24. C. Spadafora, Y. Repetto, and C. Torres Two casein kinase 1 isoforms are differentially expressed in Trypanosoma cruzi Mol Biochem Parasitol 124 2002 23 36
25. M. Calabokis, L. Kurz, and J. Wilkesman Biochemical and enzymatic characterization of a partially purified casein kinase-1 like activity from Trypanosoma cruzi Parasitol Int 51 2002 25 39
26. D.S. Roos, R.G.K. Donald, N.S. Morrissette, and A.L.C. Moulton Molecular tools for the genetic dissection of the protozoan parasite Toxoplasma gondii Methods Cell Biol 45 1994 27 63
27. E.R. Pfefferkorn, and L.C. Pfefferkorn Specific labeling of intracellular Toxoplasma gondii with uracil J Protozool 24 1977 449 453
28. D. Soldati, and J.C. Boothroyd Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii Science 260 1993 349 352
29. R.G.K. Donald, and P.A. Liberator Molecular characterization of a coccidian parasite cGMP dependent protein kinase Mol Biochem Parasitol 120 2002 165 175
30. R.E. Brown, K.L. Jarvis, and K.J. Hyland Protein measurement using bicinchoninic acid: elimination of interfering substances Anal Biochem 180 1989 136 139
31. H. Kieschnick, T. Wakefield, C.A. Narducci, and C. Beckers Toxoplasma gondii attachment to host cells is regulated by a calmodulin-like domain protein kinase J Biol Chem 276 2001 12369 12377
32. R.G.K. Donald, D. Carter, B. Ullman, and D.S. Roos Insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene. Use as a selectable marker for stable transformation J Biol Chem 271 1996 14010 14019
33. M. Knockaert, P. Greengard, and L. Meijer Pharmacological inhibitors of cyclin-dependent kinases Trends Pharmacol Sci 23 2002 417 425
34. P.P. Dunn, J.M. Bumstead, and F.M. Tomley Sequence, expression and localization of calmodulin-domain protein kinases in Eimeria tenella and Eimeria maxima Parasitology 113 1996 439 448
35. A.L. Li, B.P. Brunk, and J.C. Kissinger Gene discovery in the Apicomplexa as revealed by EST sequencing and assembly of a comparative gene database Genome Res 13 2003 443 454
36. L.J. Klimczak, D. Farini, C. Lin, D. Ponti, A.R. Cashmore, and G. Giuliano Multiple isoforms of Arabidopsis casein kinase I combine conserved catalytic domains with variable carboxyl-terminal extensions Plant Physiol 109 2 1995 687 696
37. F. Seeber Consensus sequence of translational initiation sites from Toxoplasma gondii genes Parasitol Res 83 1997 309 311
38. M. Black, F. Seeber, D. Soldati, K Kim, and J.C. Boothroyd Restriction enzyme-mediated integration elevates transformation frequency and enables co-transfection of Toxoplasma gondii Mol Biochem Parasitol 74 1995 55 63
39. L. Meijer, A.M. Thunnissen, and A.W. White Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent Chem Biol 7 1 2000 51 63
40. H. Flotow, P.R. Graves, A. Wang, C.J. Fiol, R.W. Roeske, and P.J. Roach Phosphate groups as substrate determinants for casein kinase I action J Biol Chem 265 1990 14264 14269
41. H. Flotow, and P.J. Roach Synergistic phosphorylation of rabbit muscle glycogen synthase by cyclic AMP-dependent protein kinase and casein kinase I. Implications for hormonal regulation of glycogen synthase J Biol Chem 264 16 1989 9126 9128
42. H. Flotow, and P.J. Roach Role of acidic residues as substrate determinants for casein kinase I J Biol Chem 266 6 1991 3724 3727
43. M.A. Price, and D. Kalderon Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by glycogen synthase kinase 3 and casein kinase 1 Cell 108 6 2002 823 835
44. R. Hoessel, S. Leclerc, and J.A. Endicott Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases Nat Cell Biol 1 1 1999 60 67
45. S. Leclerc, M. Garnier, and R. Hoessel Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? J Biol Chem 276 2001 251 260
46. E. Damiens, B. Baratte, D. Marie, G. Eisenbrand, and L. Meijer Anti-mitotic properties of indirubin-3′-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest Oncogene 20 29 2001 3786 3797
47. D. Marko, S. Schatzle, and A. Friedel Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells Br J Cancer 84 2 2001 283 289
48. J. Bain, H. McLauchlan, M. Elliott, and P. Cohen The specificities of protein kinase inhibitors: an update Biochem J 371 2003 199 204
49. C. Schultz, A. Link, and M. Leost Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity J Med Chem 42 15 1999 2909 2919
50. D.W. Zaharevitz, R. Gussio, and M. Leost Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases Cancer Res 59 1999 2566 2569
51. M. Knockaert, K. Wieking, and S. Schmitt Intracellular targets of paullones. Identification following affinity purification on immobilized inhibitor J Biol Chem 277 28 2002 25493 25501
52. P. Babu, J.D. Bryan, and H.R. Panek Plasma membrane localization of the Yck2p yeast casein kinase 1 isoform requires the C-terminal extension and secretory pathway function J Cell Sci 115 2002 4957 4968
53. A. Vancura, A. Sessler, B. Leichus, and J. Kuret A prenylation motif is required for plasma membrane localization and biochemical function of casein kinase I in budding yeast J Biol Chem 269 1994 19271 19278
54. M. Knockaert, P. Lenormand, N. Gray, P. Schultz, J. Pouyssegur, and L. Meijer p42/p44MAPKS are intracellular targets of the CDK inhibitor purvalanol Oncogene 21 2002 6413 6424
55. L. Harmse, R. van-Zyl, and N. Gray Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum Biochem Pharmacol 62 3 2001 341 348
56. K. LeRoch, C. Sestier, and D. Dorin Activation of a Plasmodium falciparum cdc2-related kinase by heterologous p25 and cyclin H J Biol Chem 275 12 2000 8952 8958
57. D. Dorin, K. LeRoch, and P. Sallicandro Pfnek-1, a NIMA-related kinase from the human malaria parasite Plasmodium falciparum Eur J Biochem 268 2001 2600 2608
58. A.H. Osmani, S.L. McGuire, and S.A. Osmani Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans Cell 67 1991 283 291
59. F. Khan, J. Tang, C. Qin, and K. Kim Cyclin-dependent kinase. TPK2 is a critical cell cycle regulator in Toxoplasma gondii Mol Microbiol 45 2 2002 321 332
60. J.H. Kinnaird, J.M. Bumstead, and D.J. Mann EtCRK2 a cyclin-dependent kinase gene expressed during the sexual and asexual phases of the Eimeria tenella life cycle Int J Parasitol 34 6 2004 683 692
61. C. Doerig, J. Endicott, and D. Chakrabarti Cyclin-dependent kinase homologues of Plasmodium falciparum Int J Parasitol 32 13 2002 1575 1585
62. K.L. Longenecker, P.J. Roach, and T.D. Hurley Crystallographic studies of casein kinase I delta toward a structural understanding of auto-inhibition Acta Crystallogr D: Biol Crystallogr 54 Pt 3 1998 473 475
63. K.L. Longenecker, P.J. Roach, and T.D. Hurley Three-dimensional structure of mammalian casein kinase I: molecular basis for phosphate recognition J Mol Biol 257 3 1996 618 631
64. T.G. Davies, J. Bentley, and C.E. Arris Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor Nat Struct Biol 10 2002 745 749
65. N. Mashhoon, A.J. DeMaggio, and V. Tereshko Crystal structure of a conformation-selective casein kinase-1 inhibitor J Biol Chem 275 26 2000 20052 20060
66. P. Furet X-ray crystallographic studies of CDK2, a basis for cyclin-dependent kinase inhibitor design in anti-cancer drug research. Curr Med Chem Anti Canc Agents 3 1 2003 15 23
67. S. Holton, A. Merckx, D. Burgess, C. Doerig, M. Noble, and J. Endicott Structures of P. falciparum PfPK5 test the CDK regulation paradigm and suggest mechanisms of small molecule inhibition Structure 11 11 2003 1329 1337