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Volumn 18, Issue 8, 2002, Pages 366-371

Protein kinases as drug targets in parasitic protozoa

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE; PROTEIN KINASE INHIBITOR; STAUROSPORINE;

EID: 0036697233     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4922(02)02321-8     Document Type: Review
Times cited : (85)

References (29)
  • 1
    • 0031026008 scopus 로고    scopus 로고
    • The protein kinases of budding yeast: Six score and more
    • Hunter T., Plowman G.D. The protein kinases of budding yeast: six score and more. Trends Biochem. Sci. 22:1997;18-22.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 18-22
    • Hunter, T.1    Plowman, G.D.2
  • 2
    • 0002004179 scopus 로고    scopus 로고
    • Protein phosphorylation and protein kinases in trypanosomatids
    • G. et al. Hide. CAB International
    • Boshart M., Mottram J.C. Protein phosphorylation and protein kinases in trypanosomatids. Hide G., et al. Trypanosomiasis and Leishmaniasis: Biology and Control. 1997;227-244 CAB International.
    • (1997) Trypanosomiasis and Leishmaniasis: Biology and Control , pp. 227-244
    • Boshart, M.1    Mottram, J.C.2
  • 3
    • 0033631382 scopus 로고    scopus 로고
    • The cell cycle of protozoan parasites
    • L. et al. Meijer. Kluwer Academic/Plenum
    • Doerig C., et al. The cell cycle of protozoan parasites. Meijer L., et al. Progress in Cell Cycle Research. 2000;163-183 Kluwer Academic/Plenum.
    • (2000) Progress in Cell Cycle Research , pp. 163-183
    • Doerig, C.1
  • 4
    • 0033231908 scopus 로고    scopus 로고
    • An overview of Plasmodium protein kinases
    • Kappes B., et al. An overview of Plasmodium protein kinases. Parasitol. Today. 15:1999;449-454.
    • (1999) Parasitol. Today , vol.15 , pp. 449-454
    • Kappes, B.1
  • 5
    • 0035936144 scopus 로고    scopus 로고
    • Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi
    • Katinka M.D., et al. Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi. Nature. 414:2001;450-453.
    • (2001) Nature , vol.414 , pp. 450-453
    • Katinka, M.D.1
  • 6
    • 0039278089 scopus 로고    scopus 로고
    • A MAP kinase homologue from the human malaria parasite, Plasmodium falciparum
    • Doerig C.M., et al. A MAP kinase homologue from the human malaria parasite, Plasmodium falciparum. Gene. 177:1996;1-6.
    • (1996) Gene , vol.177 , pp. 1-6
    • Doerig, C.M.1
  • 7
    • 0030891015 scopus 로고    scopus 로고
    • Interferon-γ activation of a mitogen-activated protein kinase, KFR1, in the bloodstream form of Trypanosoma brucei
    • Hua S.B., Wang C.C. Interferon-γ activation of a mitogen-activated protein kinase, KFR1, in the bloodstream form of Trypanosoma brucei. J. Biol. Chem. 272:1997;10797-10803.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10797-10803
    • Hua, S.B.1    Wang, C.C.2
  • 8
    • 0032080107 scopus 로고    scopus 로고
    • A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host
    • Wiese M. A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host. EMBO J. 17:1998;2619-2628.
    • (1998) EMBO J. , vol.17 , pp. 2619-2628
    • Wiese, M.1
  • 9
    • 0033569722 scopus 로고    scopus 로고
    • An atypical mitogen-activated protein kinase (MAPK) homologue expressed in gametocytes of the human malaria parasite Plasmodium falciparum - Identification of a MAPK signature
    • Dorin D., et al. An atypical mitogen-activated protein kinase (MAPK) homologue expressed in gametocytes of the human malaria parasite Plasmodium falciparum - identification of a MAPK signature. J. Biol. Chem. 274:1999;29912-29920.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29912-29920
    • Dorin, D.1
  • 10
    • 0035172119 scopus 로고    scopus 로고
    • Homologues of LMPK, a mitogen-activated protein kinase from Leishmania mexicana, in different Leishmania species
    • Wiese M., Gorcke I. Homologues of LMPK, a mitogen-activated protein kinase from Leishmania mexicana, in different Leishmania species. Med. Microbiol. Immunol. 190:2001;19-22.
    • (2001) Med. Microbiol. Immunol. , vol.190 , pp. 19-22
    • Wiese, M.1    Gorcke, I.2
  • 11
    • 0029896543 scopus 로고    scopus 로고
    • Leishmania chagasi: A gene encoding a protein kinase with a catalytic domain structurally related to MAP kinase kinase
    • Li S.Y., et al. Leishmania chagasi: a gene encoding a protein kinase with a catalytic domain structurally related to MAP kinase kinase. Exp. Parasitol. 82:1996;87-96.
    • (1996) Exp. Parasitol. , vol.82 , pp. 87-96
    • Li, S.Y.1
  • 12
    • 0034785963 scopus 로고    scopus 로고
    • The H89 cAMP-dependent protein kinase inhibitor blocks Plasmodium falciparum development in infected erythrocytes
    • Syin C., et al. The H89 cAMP-dependent protein kinase inhibitor blocks Plasmodium falciparum development in infected erythrocytes. Eur. J. Biochem. 268:2001;4842-4849.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 4842-4849
    • Syin, C.1
  • 13
    • 0029954373 scopus 로고    scopus 로고
    • Cloning from Leishmania major of a developmentally regulated gene, c-lpk2, for the catalytic subunit of the cAMP-dependent protein kinase
    • Siman-Tov M.M., et al. Cloning from Leishmania major of a developmentally regulated gene, c-lpk2, for the catalytic subunit of the cAMP-dependent protein kinase. Mol. Biochem. Parasitol. 77:1996;201-215.
    • (1996) Mol. Biochem. Parasitol. , vol.77 , pp. 201-215
    • Siman-Tov, M.M.1
  • 14
    • 0030806327 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a second calcium-dependent protein kinase of Plasmodium falciparum
    • Farber P.M., et al. Molecular cloning and characterization of a second calcium-dependent protein kinase of Plasmodium falciparum. Mol. Biochem. Parasitol. 87:1997;211-216.
    • (1997) Mol. Biochem. Parasitol. , vol.87 , pp. 211-216
    • Farber, P.M.1
  • 15
    • 0030705190 scopus 로고    scopus 로고
    • Identification, cloning, and mutational analysis of the casein kinase 1 cDNA of the malaria parasite, Plasmodium falciparum - Stage-specific expression of the gene
    • Barik S., et al. Identification, cloning, and mutational analysis of the casein kinase 1 cDNA of the malaria parasite, Plasmodium falciparum - stage-specific expression of the gene. J. Biol. Chem. 272:1997;26132-26138.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26132-26138
    • Barik, S.1
  • 16
    • 0034176923 scopus 로고    scopus 로고
    • PfPK6, a novel cyclin-dependent kinase/mitogen-activated protein kinase-related protein kinase from Plasmodium falciparum
    • Bracchi-Ricard V., et al. PfPK6, a novel cyclin-dependent kinase/mitogen-activated protein kinase-related protein kinase from Plasmodium falciparum. Biochem. J. 347:2000;255-263.
    • (2000) Biochem. J. , vol.347 , pp. 255-263
    • Bracchi-Ricard, V.1
  • 17
    • 0028224015 scopus 로고
    • Isolation and expression of a gene specifying a Cdc2-like protein kinase from the human malaria parasite Plasmodium falciparum
    • Ross-Macdonald P.B., et al. Isolation and expression of a gene specifying a Cdc2-like protein kinase from the human malaria parasite Plasmodium falciparum. Eur. J. Biochem. 220:1994;693-701.
    • (1994) Eur. J. Biochem. , vol.220 , pp. 693-701
    • Ross-Macdonald, P.B.1
  • 18
    • 0034850190 scopus 로고    scopus 로고
    • Pfnek-1, a NIMA-related kinase from the human malaria parasite Plasmodium falciparum - Biochemical properties and possible involvement in MAPK regulation
    • Dorin D., et al. Pfnek-1, a NIMA-related kinase from the human malaria parasite Plasmodium falciparum - biochemical properties and possible involvement in MAPK regulation. Eur. J. Biochem. 268:2001;2600-2608.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 2600-2608
    • Dorin, D.1
  • 19
    • 0028121976 scopus 로고
    • Plasmodium falciparum calcium-dependent protein kinase phosphorylates proteins of the host erythrocyte membrane
    • Zhao Y., et al. Plasmodium falciparum calcium-dependent protein kinase phosphorylates proteins of the host erythrocyte membrane. Mol. Biochem. Parasitol. 66:1994;329-343.
    • (1994) Mol. Biochem. Parasitol. , vol.66 , pp. 329-343
    • Zhao, Y.1
  • 20
    • 0036015628 scopus 로고    scopus 로고
    • A novel cyclic GMP-dependent protein kinase expressed in the ring stage of the Plasmodium falciparum life cycle
    • Deng, W. and Baker, D.A. A novel cyclic GMP-dependent protein kinase expressed in the ring stage of the Plasmodium falciparum life cycle. Mol. Microbiol. 44, 1141-1152
    • Mol. Microbiol. , vol.44 , pp. 1141-1152
    • Deng, W.1    Baker, D.A.2
  • 21
    • 0034708437 scopus 로고    scopus 로고
    • Activation of a Plasmodium falciparum Cdc2-related kinase by heterologous p25 and cyclin H - Functional characterization of a P. falciparum cyclin homologue
    • Le Roch K., et al. Activation of a Plasmodium falciparum Cdc2-related kinase by heterologous p25 and cyclin H - functional characterization of a P. falciparum cyclin homologue. J. Biol. Chem. 275:2000;8952-8958.
    • (2000) J. Biol. Chem. , vol.275 , pp. 8952-8958
    • Le Roch, K.1
  • 23
    • 0032582841 scopus 로고    scopus 로고
    • Stage-specific activity of the Leishmania major CRK3 kinase and functional rescue of a Schizosaccharomyces pombe cdc2 mutant
    • Wang Y.X., et al. Stage-specific activity of the Leishmania major CRK3 kinase and functional rescue of a Schizosaccharomyces pombe cdc2 mutant. Mol. Biochem. Parasitol. 96:1998;139-150.
    • (1998) Mol. Biochem. Parasitol. , vol.96 , pp. 139-150
    • Wang, Y.X.1
  • 24
    • 0035815349 scopus 로고    scopus 로고
    • The CRK3 protein kinase is essential for cell cycle progression of Leishmania mexicana
    • Hassan P., et al. The CRK3 protein kinase is essential for cell cycle progression of Leishmania mexicana. Mol. Biochem. Parasitol. 113:2001;189-198.
    • (2001) Mol. Biochem. Parasitol. , vol.113 , pp. 189-198
    • Hassan, P.1
  • 25
    • 0033198238 scopus 로고    scopus 로고
    • Genetic manipulation of kinetoplastida
    • Clayton C.E. Genetic manipulation of kinetoplastida. Parasitol. Today. 15:1999;372-378.
    • (1999) Parasitol. Today , vol.15 , pp. 372-378
    • Clayton, C.E.1
  • 26
    • 0037007032 scopus 로고    scopus 로고
    • The cAMP-specific phosphodiesterase TbPDE2C is an essential enzyme in bloodstream form Trypanosoma brucei
    • Zoraghi R., Seebeck T. The cAMP-specific phosphodiesterase TbPDE2C is an essential enzyme in bloodstream form Trypanosoma brucei. Proc. Natl. Acad. Sci. U. S. A. 99:2002;4343-4348.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 4343-4348
    • Zoraghi, R.1    Seebeck, T.2
  • 27
    • 0034699382 scopus 로고    scopus 로고
    • A chemical switch for inhibitor-sensitive alleles of any protein kinase
    • Bishop A.C., et al. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature. 407:2000;395-401.
    • (2000) Nature , vol.407 , pp. 395-401
    • Bishop, A.C.1
  • 28
    • 0035312350 scopus 로고    scopus 로고
    • Magic bullets for protein kinases
    • Bishop A.C., et al. Magic bullets for protein kinases. Trends Cell Biol. 11:2001;167-172.
    • (2001) Trends Cell Biol. , vol.11 , pp. 167-172
    • Bishop, A.C.1
  • 29
    • 0035947671 scopus 로고    scopus 로고
    • Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue
    • Habelhah H., et al. Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. J. Biol. Chem. 276:2001;18090-18095.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18090-18095
    • Habelhah, H.1


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