-
1
-
-
0024541436
-
Functions of sphingolipids and sphingolipid breakdown products in cellular regulation
-
Hannun YA and Bell RM: Functions of sphingolipids and sphingolipid breakdown products in cellular regulation. Science 243 500-507, 1989.
-
(1989)
Science
, vol.243
, pp. 500-507
-
-
Hannun, Y.A.1
Bell, R.M.2
-
3
-
-
0037135626
-
The Ceramide-centric universe of lipid-mediated cell regulation: Stress encounters of the lipid kind
-
Hannun YA and Obeid LM: The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind. J Biol Chem 277: 25847-25850, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25847-25850
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
4
-
-
0037203316
-
Sphingosine in apoptosis signaling
-
Cuvillier O: Sphingosine in apoptosis signaling. Biochim Biophys Acta 1585: 153-62, 2002.
-
(2002)
Biochim. Biophys. Acta
, vol.1585
, pp. 153-162
-
-
Cuvillier, O.1
-
5
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
Spiegel S and Milstien S: Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol 4: 397-407, 2003.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
6
-
-
0022512241
-
Premalignant alterations in the lipid composition and fluidity of colonic brush border membranes of rats administered 1,2 dimethylhydrazine
-
Brasitus TA, Dudeja PK and Dahiya R: Premalignant alterations in the lipid composition and fluidity of colonic brush border membranes of rats administered 1,2 dimethylhydrazine. J Clin Invest 77: 831-840, 1986.
-
(1986)
J. Clin. Invest.
, vol.77
, pp. 831-840
-
-
Brasitus, T.A.1
Dudeja, P.K.2
Dahiya, R.3
-
7
-
-
0028799257
-
Characterization of malignant colon tumors with 31P nuclear magnetic resonance phospholipid and phosphatic metabolite profiles
-
Merchant TE, Diamantis PM, Lauwers G, Haida T, Kasimos JN, Guillem J, Glonek T and Minsky BD: Characterization of malignant colon tumors with 31P nuclear magnetic resonance phospholipid and phosphatic metabolite profiles. Cancer 76: 1715-1723, 1995.
-
(1995)
Cancer
, vol.76
, pp. 1715-1723
-
-
Merchant, T.E.1
Diamantis, P.M.2
Lauwers, G.3
Haida, T.4
Kasimos, J.N.5
Guillem, J.6
Glonek, T.7
Minsky, B.D.8
-
8
-
-
0035114217
-
Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer
-
Selzner M, Bielawska A, Morse MA, Rudiger HA, Sindram D, Hannun YA and Clavien PA: Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. Cancer Res 61: 1233-1240, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 1233-1240
-
-
Selzner, M.1
Bielawska, A.2
Morse, M.A.3
Rudiger, H.A.4
Sindram, D.5
Hannun, Y.A.6
Clavien, P.A.7
-
9
-
-
0028304788
-
Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice
-
Dillehay DL, Webb SK, Schmelz EM and Merrill AH: Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice. J Nutr 124: 615-620, 1994.
-
(1994)
J. Nutr.
, vol.124
, pp. 615-620
-
-
Dillehay, D.L.1
Webb, S.K.2
Schmelz, E.M.3
Merrill, A.H.4
-
10
-
-
0029953485
-
Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas versus adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: Implications for dietary sphingolipids and colon carcinogenesis
-
Schmelz EM, Dillehay DL, Webb SK, Reiter A, Adams J and Merrill AH Jr: Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas versus adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: implications for dietary sphingolipids and colon carcinogenesis. Cancer Res 56: 4936-4941, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4936-4941
-
-
Schmelz, E.M.1
Dillehay, D.L.2
Webb, S.K.3
Reiter, A.4
Adams, J.5
Merrill Jr., A.H.6
-
11
-
-
0030818728
-
Suppression of aberrant colonic crypt foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones
-
Schmelz EM, Bushnev AS, Dillehay DL, Liotta DC and Merrill AH Jr: Suppression of aberrant colonic crypt foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones. Nutr Cancer 28: 81-85, 1997.
-
(1997)
Nutr. Cancer
, vol.28
, pp. 81-85
-
-
Schmelz, E.M.1
Bushnev, A.S.2
Dillehay, D.L.3
Liotta, D.C.4
Merrill Jr., A.H.5
-
12
-
-
0031722257
-
Ceramides and ceramide metabolites in cell regulation: Evidence for dietary sphingolipids as inhibitors of colon carcinogenesis
-
Schmelz EM and Merrill AH Jr: Ceramides and ceramide metabolites in cell regulation: evidence for dietary sphingolipids as inhibitors of colon carcinogenesis. Nutrition 14: 717-719, 1998.
-
(1998)
Nutrition
, vol.14
, pp. 717-719
-
-
Schmelz, E.M.1
Merrill Jr., A.H.2
-
13
-
-
0033571163
-
Ceramide-beta-D-glucuronide: Synthesis, digestion, and suppression of early markers of colon carcinogenesis
-
Schmelz E, Bushnev A, Dillehan DL, Sullards M, Liotta D and Merrill AH Jr: Ceramide-beta-D-glucuronide: synthesis, digestion, and suppression of early markers of colon carcinogenesis. Cancer Res 59 5768-5772, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 5768-5772
-
-
Schmelz, E.1
Bushnev, A.2
Dillehan, D.L.3
Sullards, M.4
Liotta, D.5
Merrill Jr., A.H.6
-
14
-
-
0033998537
-
Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1,2-dimethylhydrazine-treated CF1 mice
-
Schmelz EM, Sullards MC, Dillehay DL and Merrill AH Jr: Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1,2-dimethylhydrazine-treated CF1 mice. J Nutr 130: 522-527, 2000.
-
(2000)
J. Nutr.
, vol.130
, pp. 522-527
-
-
Schmelz, E.M.1
Sullards, M.C.2
Dillehay, D.L.3
Merrill Jr., A.H.4
-
15
-
-
0014422454
-
Metabolism of sphingomyelin in the intestinal tract of the rat
-
Nilsson Å: Metabolism of sphingomyelin in the intestinal tract of the rat. Biochim Biophys Acta 164: 575-584, 1968.
-
(1968)
Biochim. Biophys. Acta
, vol.164
, pp. 575-584
-
-
Nilsson, Å.1
-
16
-
-
0030964872
-
Localization and capacity of sphingomyelin digestion in the rat intestinal tract
-
Nyberg L, Nilsson Å, Lundgren P and Duan RD: Localization and capacity of sphingomyelin digestion in the rat intestinal tract. J Nutr Biochem 8: 112-118, 1997.
-
(1997)
J. Nutr. Biochem.
, vol.8
, pp. 112-118
-
-
Nyberg, L.1
Nilsson, Å.2
Lundgren, P.3
Duan, R.D.4
-
17
-
-
0036586089
-
Sphingoid bases and ceramide induce apoptosis in HT-29 and HCT-116 human colon cancer cells
-
Ahn EH and Schroeder JJ: Sphingoid bases and ceramide induce apoptosis in HT-29 and HCT-116 human colon cancer cells. Exp Biol Med (Maywood) 227: 345-353, 2002.
-
(2002)
Exp. Biol. Med. (Maywood)
, vol.227
, pp. 345-353
-
-
Ahn, E.H.1
Schroeder, J.J.2
-
18
-
-
0032842762
-
Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract
-
Nilsson Å and Duan RD: Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract. Chem Phys Lipids 102: 97-105, 1999.
-
(1999)
Chem. Phys. Lipids
, vol.102
, pp. 97-105
-
-
Nilsson, Å.1
Duan, R.D.2
-
19
-
-
0141532169
-
Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family
-
Duan RD, Bergman T, Xu N, Wu J, Cheng Y, Duan J, Nelander S, Palmberg C and Nilsson Å: Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family. J Biol Chem 278: 38528-38536, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38528-38536
-
-
Duan, R.D.1
Bergman, T.2
Xu, N.3
Wu, J.4
Cheng, Y.5
Duan, J.6
Nelander, S.7
Palmberg, C.8
Nilsson, Å.9
-
20
-
-
0028862061
-
Alkaline sphingomyelinase activity in rat gastrointestinal tract: Distribution and characteristics
-
Duan RD, Nyberg L and Nilsson Å: Alkaline sphingomyelinase activity in rat gastrointestinal tract: distribution and characteristics. Biochim Biophys Acta 1259: 49-55, 1995.
-
(1995)
Biochim. Biophys. Acta
, vol.1259
, pp. 49-55
-
-
Duan, R.D.1
Nyberg, L.2
Nilsson, Å.3
-
21
-
-
4644234388
-
Digestion and absorption of sphingolipids in food
-
Szuhaj BF and van Nieuwenhuyzen W (eds.), AOCS Press, Champaign
-
Nilsson A, Hertervig E and Duan RD: Digestion and absorption of sphingolipids in food. In: Szuhaj BF and van Nieuwenhuyzen W (eds.), Nutrition and Biochemistry of Phospholipids. AOCS Press, Champaign, pp. 70-79, 2003.
-
(2003)
Nutrition and Biochemistry of Phospholipids
, pp. 70-79
-
-
Nilsson, A.1
Hertervig, E.2
Duan, R.D.3
-
22
-
-
0242266384
-
Purified intestinal alkaline sphingomyelinase inhibits proliferation without inducing apoptosis in HT-29 colon carcinoma cells
-
Hertervig E, Nilsson A, Cheng Y and Duan RD: Purified intestinal alkaline sphingomyelinase inhibits proliferation without inducing apoptosis in HT-29 colon carcinoma cells. J Cancer Res Clin Oncol 129: 577-582, 2003
-
(2003)
J. Cancer Res. Clin. Oncol.
, vol.129
, pp. 577-582
-
-
Hertervig, E.1
Nilsson, A.2
Cheng, Y.3
Duan, R.D.4
-
23
-
-
0031023763
-
Alkaline sphingomyelinase activity is decreased in human colorectal carcinoma
-
Hertervig E, Nilsson Å, Nyberg L and Duan RD: Alkaline sphingomyelinase activity is decreased in human colorectal carcinoma. Cancer 79: 448-453, 1996.
-
(1996)
Cancer
, vol.79
, pp. 448-453
-
-
Hertervig, E.1
Nilsson, Å.2
Nyberg, L.3
Duan, R.D.4
-
24
-
-
0032857215
-
Familial adenomatous polyposis is associated with a marked decrease in alkaline sphingomyelinase activity; a key factor to the unrestrained cell proliferation
-
Hertervig E, Nilsson Å, Björk J, Hultkrantz R and Duan RD: Familial adenomatous polyposis is associated with a marked decrease in alkaline sphingomyelinase activity; a key factor to the unrestrained cell proliferation. Br J Cancer 81: 232-236, 1999.
-
(1999)
Br. J. Cancer
, vol.81
, pp. 232-236
-
-
Hertervig, E.1
Nilsson, Å.2
Björk, J.3
Hultkrantz, R.4
Duan, R.D.5
-
25
-
-
0036066564
-
Chronic colitis is associated with a reduction of mucosal alkaline sphingomyelinase activity
-
Sjöqvist U, Hertervig E, Nilsson Å, Duan RD, Ost A, Tribukait B and Lofberg R: Chronic colitis is associated with a reduction of mucosal alkaline sphingomyelinase activity. Inflamm Bowel Dis 8: 258-263, 2002.
-
(2002)
Inflamm. Bowel Dis.
, vol.8
, pp. 258-263
-
-
Sjöqvist, U.1
Hertervig, E.2
Nilsson, Å.3
Duan, R.D.4
Ost, A.5
Tribukait, B.6
Lofberg, R.7
-
26
-
-
4344656249
-
Identification of one exon deletion of intestinal alkaline sphingomyelinase in colon cancer HT-29 cells and a differentiation-related expression of the wild-type enzyme in Caco-2 cells
-
Wu J, Cheng Y, Nilsson Å and Duan RD: Identification of one exon deletion of intestinal alkaline sphingomyelinase in colon cancer HT-29 cells and a differentiation-related expression of the wild-type enzyme in Caco-2 cells. Carcinogenesis 25: 1327-1333, 2004.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1327-1333
-
-
Wu, J.1
Cheng, Y.2
Nilsson, Å.3
Duan, R.D.4
-
27
-
-
4644329211
-
Rat intestinal ceramidase: Purification, properties, and physiological relevance
-
Olsson M, Duan RD, Ohlsson L and Nilsson Å: Rat intestinal ceramidase: purification, properties, and physiological relevance. Am J Physiol Gastrointest Liver Physiol 287: G929-937, 2004.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.287
-
-
Olsson, M.1
Duan, R.D.2
Ohlsson, L.3
Nilsson, Å.4
-
28
-
-
0035027916
-
Distribution and properties of neutral ceramidase activity in rat intestinal tract
-
Lundgren P, Nilsson Å and Duan RD: Distribution and properties of neutral ceramidase activity in rat intestinal tract. Dig Dis Sci 46: 765-772, 2001.
-
(2001)
Dig. Dis. Sci.
, vol.46
, pp. 765-772
-
-
Lundgren, P.1
Nilsson, Å.2
Duan, R.D.3
-
29
-
-
0034809734
-
Evidence for specific ceramidase present in the intestinal contents of rats and humans
-
Duan RD, Cheng Y, Yang L, Ohlsson L and Nilsson Å: Evidence for specific ceramidase present in the intestinal contents of rats and humans. Lipids 36: 807-812, 2001.
-
(2001)
Lipids
, vol.36
, pp. 807-812
-
-
Duan, R.D.1
Cheng, Y.2
Yang, L.3
Ohlsson, L.4
Nilsson, Å.5
-
30
-
-
0013805379
-
The metabolism of glucocerebrosides. 3. Purification and properties of a glucosyl- and galactosylceramide-cleaving enzyme from rat intestinal tissue
-
Brady RO, Gal AE, Kanfer JN and Bradley RM: The metabolism of glucocerebrosides. 3. Purification and properties of a glucosyl- and galactosylceramide-cleaving enzyme from rat intestinal tissue. J Biol Chem 240: 3766-3770, 1965.
-
(1965)
J. Biol. Chem.
, vol.240
, pp. 3766-3770
-
-
Brady, R.O.1
Gal, A.E.2
Kanfer, J.N.3
Bradley, R.M.4
-
31
-
-
0015714423
-
On the identity between the small intestinal enzymes phlorizin hydrolase and glycosylceramidase
-
Leese HJ and Semenza G: On the identity between the small intestinal enzymes phlorizin hydrolase and glycosylceramidase. J Biol Chem 248: 8170-8173, 1973.
-
(1973)
J. Biol. Chem.
, vol.248
, pp. 8170-8173
-
-
Leese, H.J.1
Semenza, G.2
-
32
-
-
0019495749
-
A taurodeoxycholate-activated galactosylceramidase in the murine intestine
-
Kobayashi T and Suzuki K: A taurodeoxycholate-activated galactosylceramidase in the murine intestine. J Biol Chem 256: 1133-1137, 1981.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 1133-1137
-
-
Kobayashi, T.1
Suzuki, K.2
-
33
-
-
0019857253
-
The glycosylceramidase in the murine intestine. Purification and substrate specificity
-
Kobayashi T and Suzuki K: The glycosylceramidase in the murine intestine. Purification and substrate specificity. J Biol Chem 256: 7768-7773, 1981.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 7768-7773
-
-
Kobayashi, T.1
Suzuki, K.2
-
34
-
-
0023693757
-
Degradation of human intestinal glycosphingolipids by extracellular glycosidases from mucin-degrading bacteria of the human fecal flora
-
Larson G, Falk P and Hoskins LC: Degradation of human intestinal glycosphingolipids by extracellular glycosidases from mucin-degrading bacteria of the human fecal flora. J Biol Chem 263: 10790-10798, 1988.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 10790-10798
-
-
Larson, G.1
Falk, P.2
Hoskins, L.C.3
-
35
-
-
0025831658
-
Enhancing effects of bile salts on the degradation of glycosphingolipids by glycosidases from bacteria of the human fecal flora
-
Falk P, Hoskins LC and Larson G: Enhancing effects of bile salts on the degradation of glycosphingolipids by glycosidases from bacteria of the human fecal flora. Biochim Biophys Acta 1084: 139-148, 1991.
-
(1991)
Biochim. Biophys. Acta
, vol.1084
, pp. 139-148
-
-
Falk, P.1
Hoskins, L.C.2
Larson, G.3
-
36
-
-
0037400136
-
Effects of sphingomyelin on aberrant colonic crypt foci development, colon crypt cell proliferation and immune function in an aging rat tumor model
-
Exon JH and South EH: Effects of sphingomyelin on aberrant colonic crypt foci development, colon crypt cell proliferation and immune function in an aging rat tumor model. Food Chem Toxicol 41: 471-476, 2003.
-
(2003)
Food. Chem. Toxicol.
, vol.41
, pp. 471-476
-
-
Exon, J.H.1
South, E.H.2
-
37
-
-
0142258006
-
Sphingomyelin in the suppression of colon tumors: Prevention versus intervention
-
Lemonnier LA, Dillehay DL, Vespremi MJ, Abrams J, Brody E and Schmelz EM: Sphingomyelin in the suppression of colon tumors: prevention versus intervention. Arch Biochem Biophys 419: 129-138, 2003.
-
(2003)
Arch. Biochem. Biophys.
, vol.419
, pp. 129-138
-
-
Lemonnier, L.A.1
Dillehay, D.L.2
Vespremi, M.J.3
Abrams, J.4
Brody, E.5
Schmelz, E.M.6
-
38
-
-
2442571212
-
Dietary soy sphingolipids suppress tumorigenesis and gene expression in 1,2-dimethylhydrazine-treated CF1 mice and ApcMin/+ mice
-
Symolon H, Schmelz EM, Dillehay DL and Merrill AH Jr: Dietary soy sphingolipids suppress tumorigenesis and gene expression in 1,2-dimethylhydrazine-treated CF1 mice and ApcMin/+ mice. J Nutr 134 1157-1161, 2004.
-
(2004)
J. Nutr.
, vol.134
, pp. 1157-1161
-
-
Symolon, H.1
Schmelz, E.M.2
Dillehay, D.L.3
Merrill Jr., A.H.4
-
40
-
-
0038541971
-
Sphingomyelin protects against apoptosis and hyperproliferation induced by deoxycholate: Potential implications for colon cancer
-
Moschetta A, Portincasa P, van Erpecum KJ, Debellis L, Vanberge-Henegouwen GP and Palasciano G: Sphingomyelin protects against apoptosis and hyperproliferation induced by deoxycholate: potential implications for colon cancer. Dig Dis Sci 48: 1094-1101, 2003.
-
(2003)
Dig. Dis. Sci.
, vol.48
, pp. 1094-1101
-
-
Moschetta, A.1
Portincasa, P.2
van Erpecum, K.J.3
Debellis, L.4
Vanberge-Henegouwen, G.P.5
Palasciano, G.6
-
41
-
-
0038544130
-
Milk sphingomyelin accelerates enzymatic and morphological maturation of the intestine in artificially reared rats
-
Motouri M, Matsuyama H, Yamamura J, Tanaka M, Aoe S, Iwanaga T and Kawakami H: Milk sphingomyelin accelerates enzymatic and morphological maturation of the intestine in artificially reared rats. J Pediatr Gastroenterol Nutr 36: 241-247, 2003.
-
(2003)
J. Pediatr. Gastroenterol. Nutr.
, vol.36
, pp. 241-247
-
-
Motouri, M.1
Matsuyama, H.2
Yamamura, J.3
Tanaka, M.4
Aoe, S.5
Iwanaga, T.6
Kawakami, H.7
-
42
-
-
0029148660
-
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
-
Bose R, Verheij M, Haimovitz-Friedman A, Scotto K, Fuks Z and Kolesnick R: Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell 82: 405-414, 1995.
-
(1995)
Cell
, vol.82
, pp. 405-414
-
-
Bose, R.1
Verheij, M.2
Haimovitz-Friedman, A.3
Scotto, K.4
Fuks, Z.5
Kolesnick, R.6
-
43
-
-
0034614095
-
Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism
-
Maurer BJ, Melton L, Billups C, Cabot MC and Reynolds CP: Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism. J Natl Cancer Inst 92: 1897-1909, 2000.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1897-1909
-
-
Maurer, B.J.1
Melton, L.2
Billups, C.3
Cabot, M.C.4
Reynolds, C.P.5
-
44
-
-
0036551283
-
Ceramide involvement in homocamptothecin- and camptothecin-induced cytotoxicity and apoptosis in colon HT29 cells
-
Chauvier D, Morjani H and Manfait M: Ceramide involvement in homocamptothecin- and camptothecin-induced cytotoxicity and apoptosis in colon HT29 cells. Int J Oncol 20: 855-863, 2002.
-
(2002)
Int. J. Oncol.
, vol.20
, pp. 855-863
-
-
Chauvier, D.1
Morjani, H.2
Manfait, M.3
-
45
-
-
0038445608
-
Non-steroidal anti-inflammatory drugs and molecular carcinogenesis of colorectal carcinomas
-
Huls G, Koornstra JJ and Kleibeuker JH: Non-steroidal anti-inflammatory drugs and molecular carcinogenesis of colorectal carcinomas. Lancet 362: 230-232, 2003.
-
(2003)
Lancet
, vol.362
, pp. 230-232
-
-
Huls, G.1
Koornstra, J.J.2
Kleibeuker, J.H.3
-
46
-
-
0028070326
-
Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha
-
Jayadev S, Linardic CM and Hannun YA: Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha. J Biol Chem 269: 5757-5763, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 5757-5763
-
-
Jayadev, S.1
Linardic, C.M.2
Hannun, Y.A.3
-
47
-
-
0035999526
-
In vitro effects of fat, fatty acids, and cholesterol on sphingomyelin hydrolysis induced by rat intestinal alkaline sphingomyelinase
-
2002
-
Liu JJ, Nilsson Å and Duan RD: In vitro effects of fat, fatty acids, and cholesterol on sphingomyelin hydrolysis induced by rat intestinal alkaline sphingomyelinase. Lipids 37: 469-474, 2002, 2002.
-
(2002)
Lipids
, vol.37
, pp. 469-474
-
-
Liu, J.J.1
Nilsson, Å.2
Duan, R.D.3
-
48
-
-
0036152656
-
Aminosalicylates: Potential antineoplastic actions in colon cancer
-
Allgayer H and Kruis W: Aminosalicylates: potential antineoplastic actions in colon cancer. Scand J Gastroenterol 37: 125-131, 2002.
-
(2002)
Scand. J. Gastroenterol.
, vol.37
, pp. 125-131
-
-
Allgayer, H.1
Kruis, W.2
-
49
-
-
14244266592
-
Potential link between sphingomyelin metabolism and colonic tumorigenesis
-
Scheppach W and Scheurlen M (eds.), Kluwer Academic Publishers, Lancaster, UK
-
Duan RD: Potential link between sphingomyelin metabolism and colonic tumorigenesis. In: Scheppach W and Scheurlen M (eds.), Exogenous Factors in Colonic Carcinogenesis. Kluwer Academic Publishers, Lancaster, UK., pp. 142-153, 2003.
-
(2003)
Exogenous Factors in Colonic Carcinogenesis
, pp. 142-153
-
-
Duan, R.D.1
-
50
-
-
0036949876
-
Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells
-
Liu JJ, Nilsson Å, Oredsson S, Badmaev V, Zhao WZ and Duan RD: Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 23: 2087-2093, 2002.
-
(2002)
Carcinogenesis
, vol.23
, pp. 2087-2093
-
-
Liu, J.J.1
Nilsson, Å.2
Oredsson, S.3
Badmaev, V.4
Zhao, W.Z.5
Duan, R.D.6
-
51
-
-
0042530176
-
Ursolic acid inhibits proliferation and stimulates apoptosis in HT29 cells following activation of alkaline sphingomyelinase
-
Andersson D, Liu JJ, Nilsson Å and Duan RD: Ursolic acid inhibits proliferation and stimulates apoptosis in HT29 cells following activation of alkaline sphingomyelinase. Anticancer Res 23: 3317-3322, 2003.
-
(2003)
Anticancer. Res.
, vol.23
, pp. 3317-3322
-
-
Andersson, D.1
Liu, J.J.2
Nilsson, Å.3
Duan, R.D.4
-
52
-
-
0028072163
-
Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid
-
Earnest DL, Holubec H, Wali RK, Jolley CS, Bissonette M, Bhattacharyya AK, Roy H, Khare S and Brasitus TA: Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid. Cancer Res 54: 5071-5074, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5071-5074
-
-
Earnest, D.L.1
Holubec, H.2
Wali, R.K.3
Jolley, C.S.4
Bissonette, M.5
Bhattacharyya, A.K.6
Roy, H.7
Khare, S.8
Brasitus, T.A.9
-
53
-
-
0038418399
-
Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer
-
Khare S, Cerda S, Wali RK, von Lintig FC, Tretiakova M, Joseph L, Stoiber D, Cohen G, Nimmagadda K, Hart J, Sitrin MD, Boss GR and Bissonnette M: Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer. Cancer Res 63: 3517-3523, 2003.
-
(2003)
Cancer Res.
, vol.63
, pp. 3517-3523
-
-
Khare, S.1
Cerda, S.2
Wali, R.K.3
von Lintig, F.C.4
Tretiakova, M.5
Joseph, L.6
Stoiber, D.7
Cohen, G.8
Nimmagadda, K.9
Hart, J.10
Sitrin, M.D.11
Boss, G.R.12
Bissonnette, M.13
-
54
-
-
0037382288
-
Ursodeoxycholic acid as a chemopreventive agent in patients with ulcerative colitis and primary sclerosing cholangitis
-
Pardi DS, Loftus EV Jr, Kremers WK, Keach J and Lindor KD: Ursodeoxycholic acid as a chemopreventive agent in patients with ulcerative colitis and primary sclerosing cholangitis. Gastroenterology 124: 889-893, 2003.
-
(2003)
Gastroenterology
, vol.124
, pp. 889-893
-
-
Pardi, D.S.1
Loftus Jr., E.V.2
Kremers, W.K.3
Keach, J.4
Lindor, K.D.5
-
55
-
-
0032885918
-
Administration of ursodeoxycholic acid increases the activities of alkaline sphingomyelinase and caspase-3 in rat colon
-
Cheng Y, Tauschel HT, Nilsson Å and Duan RD: Administration of ursodeoxycholic acid increases the activities of alkaline sphingomyelinase and caspase-3 in rat colon. Scand J Gastroenterol 34: 915-920, 1999.
-
(1999)
Scand. J. Gastroenterol.
, vol.34
, pp. 915-920
-
-
Cheng, Y.1
Tauschel, H.T.2
Nilsson, Å.3
Duan, R.D.4
-
57
-
-
0029966199
-
beta-Sitosterol inhibits HT-29 human colon cancer cell growth and alters membrane lipids
-
Awad AB, Chen YC, Fink CS and Hennessey T: beta-Sitosterol inhibits HT-29 human colon cancer cell growth and alters membrane lipids. Anticancer Res 16: 2797-2804,1996.
-
(1996)
Anticancer Res.
, vol.16
, pp. 2797-2804
-
-
Awad, A.B.1
Chen, Y.C.2
Fink, C.S.3
Hennessey, T.4
-
58
-
-
0031742610
-
beta-Sitosterol activates the sphingomyelin cycle and induces apoptosis in LNCaP human prostate cancer cells
-
von Holtz RL, Fink CS and Awad AB: beta-Sitosterol activates the sphingomyelin cycle and induces apoptosis in LNCaP human prostate cancer cells. Nutr Cancer 32: 8-12,1998.
-
(1998)
Nutr. Cancer
, vol.32
, pp. 8-12
-
-
von Holtz, R.L.1
Fink, C.S.2
Awad, A.B.3
-
59
-
-
0018872473
-
Protective effect of plant sterols against chemically induced colon tumors in rats
-
Raicht R.F, Cohen BI, Fazzini EP, Sarwal AN and Takahashi M: Protective effect of plant sterols against chemically induced colon tumors in rats. Cancer Res 40: 403-405, 1980.
-
(1980)
Cancer Res.
, vol.40
, pp. 403-405
-
-
Raicht, R.F.1
Cohen, B.I.2
Fazzini, E.P.3
Sarwal, A.N.4
Takahashi, M.5
-
60
-
-
0034967440
-
Plant sterol intakes and colorectal cancer risk in the Netherlands Cohort Study on Diet and Cancer
-
Normen AL, Brants HA, Voorrips LE, Andersson HA, van den Brandt PA and Goldbohm RA: Plant sterol intakes and colorectal cancer risk in the Netherlands Cohort Study on Diet and Cancer. Am J Clin Nutr 74: 141-148, 2001.
-
(2001)
Am. J. Clin. Nutr.
, vol.74
, pp. 141-148
-
-
Normen, A.L.1
Brants, H.A.2
Voorrips, L.E.3
Andersson, H.A.4
van den Brandt, P.A.5
Goldbohm, R.A.6
-
61
-
-
0029934578
-
Dietary fat and fiber differentially alter intracellular second messengers during tumor development in rat colon
-
Jiang YH, Lupton JR, Chang WC, Jolly CA, Aukema HM and Chapkin RS: Dietary fat and fiber differentially alter intracellular second messengers during tumor development in rat colon. Carcinogenesis 17: 1227-1233,1996.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1227-1233
-
-
Jiang, Y.H.1
Lupton, J.R.2
Chang, W.C.3
Jolly, C.A.4
Aukema, H.M.5
Chapkin, R.S.6
-
62
-
-
0032416737
-
Role of red meat and arachidonic acid in protein kinase C activation in rat colonic musosa
-
Pajari AM, Häkkänen P, Duan RD and Mutanen M: Role of red meat and arachidonic acid in protein kinase C activation in rat colonic musosa. Nutr Cancer 32: 86-94, 1998.
-
(1998)
Nutr. Cancer
, vol.32
, pp. 86-94
-
-
Pajari, A.M.1
Häkkänen, P.2
Duan, R.D.3
Mutanen, M.4
-
63
-
-
2542631152
-
Psyllium and fat in diets differentially affect the activities and expressions of colonic sphingomyelinases and caspase in mice
-
Cheng Y, Ohlsson L and Duan RD: Psyllium and fat in diets differentially affect the activities and expressions of colonic sphingomyelinases and caspase in mice. Br J Nutr 91: 715-723, 2004.
-
(2004)
Br. J. Nutr.
, vol.91
, pp. 715-723
-
-
Cheng, Y.1
Ohlsson, L.2
Duan, R.D.3
-
64
-
-
0036053298
-
Effects of fat, beef and fiber in diets on activities of sphingomyelinase, ceramidase and caspase-3 in rat colonic mucosa
-
Yang L, Mutanen M, Cheng Y and Duan RD: Effects of fat, beef and fiber in diets on activities of sphingomyelinase, ceramidase and caspase-3 in rat colonic mucosa. Med Princ Pract 11: 150-156, 2002.
-
(2002)
Med. Princ. Pract.
, vol.11
, pp. 150-156
-
-
Yang, L.1
Mutanen, M.2
Cheng, Y.3
Duan, R.D.4
-
65
-
-
0036342813
-
Effects of red meat and fiber in high fat diet on activities of sphingomyelinase, ceramidase and caspase-3 in rat colonic mucosa
-
Yang L, Mutanen M, Cheng Y and Duan RD: Effects of red meat and fiber in high fat diet on activities of sphingomyelinase, ceramidase and caspase-3 in rat colonic mucosa. J Nutr Biochem 13: 499-504, 2002.
-
(2002)
J. Nutr. Biochem.
, vol.13
, pp. 499-504
-
-
Yang, L.1
Mutanen, M.2
Cheng, Y.3
Duan, R.D.4
-
66
-
-
0033192445
-
Ceramide toxicity and metabolism differ in wild-type and multidrug-resistant cancer cells
-
Lucci A, Giuliano AE, Han TY, Dinur T, Liu YY, Senchenkov A and Cabot MC: Ceramide toxicity and metabolism differ in wild-type and multidrug-resistant cancer cells. Int J Oncol 15: 535-540,1999.
-
(1999)
Int. J. Oncol.
, vol.15
, pp. 535-540
-
-
Lucci, A.1
Giuliano, A.E.2
Han, T.Y.3
Dinur, T.4
Liu, Y.Y.5
Senchenkov, A.6
Cabot, M.C.7
-
67
-
-
0031019309
-
Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells
-
Lavie Y, Cao H, Volner A, Lucci A, Han TY, Geffen V, Giuliano AE and Cabot MC: Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells. J Biol Chem 272: 1682-1687, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1682-1687
-
-
Lavie, Y.1
Cao, H.2
Volner, A.3
Lucci, A.4
Han, T.Y.5
Geffen, V.6
Giuliano, A.E.7
Cabot, M.C.8
-
68
-
-
4444364174
-
Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy
-
Gouaze V, Yu JY, Bleicher RJ, Han TY, Liu YY, Wang H, Gottesman MM, Bitterman A, Giuliano AE and Cabot MC: Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy. Mol Cancer Ther 3: 633-639, 2004.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 633-639
-
-
Gouaze, V.1
Yu, J.Y.2
Bleicher, R.J.3
Han, T.Y.4
Liu, Y.Y.5
Wang, H.6
Gottesman, M.M.7
Bitterman, A.8
Giuliano, A.E.9
Cabot, M.C.10
-
69
-
-
2442675466
-
MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells
-
Klappe K, Hinrichs JW, Kroesen BJ, Sietsma H and Kok JW: MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells. Int J Cancer 110: 511-522, 2004.
-
(2004)
Int. J. Cancer
, vol.110
, pp. 511-522
-
-
Klappe, K.1
Hinrichs, J.W.2
Kroesen, B.J.3
Sietsma, H.4
Kok, J.W.5
-
70
-
-
0028913218
-
Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth
-
Abe A, Radin NS, Shayman JA, Wotring LL, Zipkin RE, Sivakumar R, Ruggier JM, Carson KG and Ganem B: Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth. J Lipid Res 36: 611-621, 1995.
-
(1995)
J. Lipid Res.
, vol.36
, pp. 611-621
-
-
Abe, A.1
Radin, N.S.2
Shayman, J.A.3
Wotring, L.L.4
Zipkin, R.E.5
Sivakumar, R.6
Ruggier, J.M.7
Carson, K.G.8
Ganem, B.9
-
71
-
-
0035829464
-
Design, synthesis, and characterization of the antitumor activity of novel ceramide analogues
-
Macchia M, Barontini S, Bertini S, Di Bussolo V, Fogli S, Giovannetti E, Grossi E, Minutolo F and Danesi R: Design, synthesis, and characterization of the antitumor activity of novel ceramide analogues. J Med Chem 44: 3994-4000, 2001.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 3994-4000
-
-
Macchia, M.1
Barontini, S.2
Bertini, S.3
Di Bussolo, V.4
Fogli, S.5
Giovannetti, E.6
Grossi, E.7
Minutolo, F.8
Danesi, R.9
-
72
-
-
0038641944
-
Killing tumours by ceramide-induced apoptosis: A critique of available drugs
-
Radin NS: Killing tumours by ceramide-induced apoptosis: a critique of available drugs. Biochem J 371: 243-256, 2003.
-
(2003)
Biochem. J.
, vol.371
, pp. 243-256
-
-
Radin, N.S.1
-
73
-
-
1942506033
-
Poly-drug cancer therapy based on ceramide
-
Radin NS: Poly-drug cancer therapy based on ceramide. Eksp Onkol 26: 3-10, 2004.
-
(2004)
Eksp. Onkol.
, vol.26
, pp. 3-10
-
-
Radin, N.S.1
|