-
1
-
-
0029862561
-
Sphingolipid metabolism and growth regulation
-
Spiegel, S, and Merrill, AH, Jr: "Sphingolipid metabolism and growth regulation." FASEB J 10, 1388-1397, 1996.
-
(1996)
FASEB J
, vol.10
, pp. 1388-1397
-
-
Spiegel, S.1
Merrill Jr., A.H.2
-
2
-
-
0028235958
-
Uptake and metabolism of sphingolipids in isolated intestinal loops
-
Schmelz, EM, Crall, KJ, Laroque, R, Dillehay, DL, and Merrill, AH, Jr: "Uptake and metabolism of sphingolipids in isolated intestinal loops." J Nutr 124, 702-712, 1994.
-
(1994)
J Nutr
, vol.124
, pp. 702-712
-
-
Schmelz, E.M.1
Crall, K.J.2
Laroque, R.3
Dillehay, D.L.4
Merrill Jr., A.H.5
-
3
-
-
0029953485
-
Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas versus adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: Implications for dietary sphingolipids and colon carcinogenesis
-
Schmelz, EM, Dillehay, DL, Webb, SK, Reiter, A, Adams, J, et al.: "Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas versus adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: implications for dietary sphingolipids and colon carcinogenesis." Cancer Res 56, 4936-4941, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 4936-4941
-
-
Schmelz, E.M.1
Dillehay, D.L.2
Webb, S.K.3
Reiter, A.4
Adams, J.5
-
4
-
-
0028304788
-
Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice
-
Dillehay, DL, Webb, SK, Schmelz, EM, and Merrill, AH, Jr: "Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice." J Nutr 124, 615-620, 1994.
-
(1994)
J Nutr
, vol.124
, pp. 615-620
-
-
Dillehay, D.L.1
Webb, S.K.2
Schmelz, E.M.3
Merrill Jr., A.H.4
-
5
-
-
0003633755
-
-
Bethesda, MD: Natl Inst Health, [Publ 88-23 (rev)]
-
National Research Council: Guide for the Care and Use of Laboratory Animals. Bethesda, MD: Natl Inst Health, 1985. [Publ 88-23 (rev)]
-
(1985)
Guide for the Care and Use of Laboratory Animals
-
-
-
6
-
-
33845282544
-
The synthesis and configurational stability of differentially protected β-hydroxy-α-amino aldehydes
-
Garner, P, and Park, JM: "The synthesis and configurational stability of differentially protected β-hydroxy-α-amino aldehydes." J Org Chem 52, 2361-2364, 1987.
-
(1987)
J Org Chem
, vol.52
, pp. 2361-2364
-
-
Garner, P.1
Park, J.M.2
-
7
-
-
0023684709
-
A stereodivergent synthesis of D-erythro-sphingosine and D-erythro-sphinganine from L-serine
-
Garner, P, Park, JM, and Malecki, E: "A stereodivergent synthesis of D-erythro-sphingosine and D-erythro-sphinganine from L-serine." J Org Chem 53, 4395-4398, 1988.
-
(1988)
J Org Chem
, vol.53
, pp. 4395-4398
-
-
Garner, P.1
Park, J.2
Malecki, E.3
-
8
-
-
0003161893
-
1,1-Dimethylethyl (S)- Or (R)-4-formyl-2,2 dimethyl-3-oxazolidinecarboxylate: A useful serinal derivative
-
Gamer, P, and Park, JM: "1,1-Dimethylethyl (S)-or (R)-4-formyl-2,2 dimethyl-3-oxazolidinecarboxylate: a useful serinal derivative." Org Synth 70, 18-28, 1991.
-
(1991)
Org Synth
, vol.70
, pp. 18-28
-
-
Gamer, P.1
Park, J.M.2
-
9
-
-
0023838180
-
Synthesis of D-erythro- and D-threo-sphingosine derivatives from L-serine
-
Herold, P: "Synthesis of D-erythro- and D-threo-sphingosine derivatives from L-serine." Helv Chim Acta 71, 354-362, 1988.
-
(1988)
Helv Chim Acta
, vol.71
, pp. 354-362
-
-
Herold, P.1
-
10
-
-
17244367831
-
2+-ATPaSe activator, from Symbiodinum sp
-
2+-ATPaSe activator, from Symbiodinum sp." J Chem Soc Perkin Trans 1, 343-350, 1992.
-
(1992)
J Chem Soc Perkin Trans
, vol.1
, pp. 343-350
-
-
Yoshida, J.1
Nakagawa, M.2
Seki, H.3
Hino, T.4
-
11
-
-
0023904902
-
A stereo-selective synthesis of sphingosine, a protein kinase C inhibitor
-
Nimkar, S, Menaldino, D, Merrill, AH, Jr, and Liotta, DC: "A stereo-selective synthesis of sphingosine, a protein kinase C inhibitor." Tetrahedron Lett 29, 3037-3040, 1988.
-
(1988)
Tetrahedron Lett
, vol.29
, pp. 3037-3040
-
-
Nimkar, S.1
Menaldino, D.2
Merrill Jr., A.H.3
Liotta, D.C.4
-
12
-
-
0343787293
-
H-Phosphonate and phosphoramidite methods for the synthesis of phosphosphingolipids
-
Frantova, AY, Bushnev, AS, Zvonkova, EN, and Shvets, VI: "H-Phosphonate and phosphoramidite methods for the synthesis of phosphosphingolipids." Bioorgan Khim 17, 1562-1573, 1991. (English abstr: Chem Abstr 116, 1363, 1991)
-
(1991)
Bioorgan Khim
, vol.17
, pp. 1562-1573
-
-
Frantova, A.Y.1
Bushnev, A.S.2
Zvonkova, E.N.3
Shvets, V.I.4
-
13
-
-
1842363975
-
-
Frantova, AY, Bushnev, AS, Zvonkova, EN, and Shvets, VI: "H-Phosphonate and phosphoramidite methods for the synthesis of phosphosphingolipids." Bioorgan Khim 17, 1562-1573, 1991. (English abstr: Chem Abstr 116, 1363, 1991)
-
(1991)
Chem Abstr
, vol.116
, pp. 1363
-
-
-
14
-
-
37049071324
-
Synthesis and spectral properties of chemically and stereochemically homogeneous sphingomyelin and its analogues
-
Bruzik, KS: "Synthesis and spectral properties of chemically and stereochemically homogeneous sphingomyelin and its analogues." J Chem Soc Perkin Trans 1, 423-431, 1988.
-
(1988)
J Chem Soc Perkin Trans
, vol.1
, pp. 423-431
-
-
Bruzik, K.S.1
-
15
-
-
0343879238
-
Assay of inorganic phosphate, total phosphate and phosphatases
-
Ames, BN: "Assay of inorganic phosphate, total phosphate and phosphatases." Methods Enzymol 8, 115-118, 1966.
-
(1966)
Methods Enzymol
, vol.8
, pp. 115-118
-
-
Ames, B.N.1
-
16
-
-
0017375321
-
Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutrition Studies
-
American Institute of Nutrition: "Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutrition Studies." J Nutr 107, 1340-1348, 1977.
-
(1977)
J Nutr
, vol.107
, pp. 1340-1348
-
-
-
17
-
-
0023951016
-
Quantitation of free sphingosine in liver by high-performance liquid chromatography
-
Merrill, AH, Jr, Wang, E, Mullins, RE, Jamison, WCL, Nimkar, S, et al.: "Quantitation of free sphingosine in liver by high-performance liquid chromatography." Anal Chem 171, 373-381, 1988.
-
(1988)
Anal Chem
, vol.171
, pp. 373-381
-
-
Merrill Jr., A.H.1
Wang, E.2
Mullins, R.E.3
Jamison, W.C.L.4
Nimkar, S.5
-
18
-
-
0023629080
-
Observations and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings
-
Bird, RP: "Observations and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings." Cancer Lett 37, 147-151, 1987.
-
(1987)
Cancer Lett
, vol.37
, pp. 147-151
-
-
Bird, R.P.1
-
19
-
-
0027762512
-
Sphingolipid breakdown products: Antiproliferative and tumor suppressor lipids
-
Hannun, YA, and Linardic, CM: "Sphingolipid breakdown products: antiproliferative and tumor suppressor lipids." Biochim Biophys Acta 1154, 223-236, 1993.
-
(1993)
Biochim Biophys Acta
, vol.1154
, pp. 223-236
-
-
Hannun, Y.A.1
Linardic, C.M.2
-
20
-
-
0026049696
-
Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation
-
Zhang, H, Desai, NN, Olivera, A, Seki, T, Brooker, G, et al.: "Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation." J Cell Biol 114, 155-167, 1991.
-
(1991)
J Cell Biol
, vol.114
, pp. 155-167
-
-
Zhang, H.1
Desai, N.N.2
Olivera, A.3
Seki, T.4
Brooker, G.5
-
21
-
-
0025019387
-
Characteristics of the growth inhibition and cytotoxicity of long-chain (sphingoid) bases for Chinese hamster ovary cells: Evidence for an involvement of protein kinase C
-
Stevens, VL, Nimkar, S, Jameson, WC, Liotta, DC, and Merrill, AH, Jr: "Characteristics of the growth inhibition and cytotoxicity of long-chain (sphingoid) bases for Chinese hamster ovary cells: evidence for an involvement of protein kinase C." Biochim Biophys Acta 1051, 37-15, 1990.
-
(1990)
Biochim Biophys Acta
, vol.1051
, pp. 37-115
-
-
Stevens, V.L.1
Nimkar, S.2
Jameson, W.C.3
Liotta, D.C.4
Merrill Jr., A.H.5
-
22
-
-
0028930533
-
Role for ceramide in cell cycle arrest
-
Jayadev, S, Liu, B, Bielawska, AE, Lee, JY, Nazaire, F, et al.: "Role for ceramide in cell cycle arrest." J Biol Chem 270, 2047-2052, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 2047-2052
-
-
Jayadev, S.1
Liu, B.2
Bielawska, A.E.3
Lee, J.Y.4
Nazaire, F.5
-
23
-
-
0023014094
-
Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases
-
Merrill, AH, Jr, Sereni, AM, Stevens, VL, Hannun, YA, Bell, RM, et al.: "Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases." J Biol Chem 261, 12610-12615, 1986.
-
(1986)
J Biol Chem
, vol.261
, pp. 12610-12615
-
-
Merrill Jr., A.H.1
Sereni, A.M.2
Stevens, V.L.3
Hannun, Y.A.4
Bell, R.M.5
-
24
-
-
0025186723
-
Modulation of retinoic acid-induced differentiation of human leukemia (HL-60) cells by serum factors and sphinganine
-
Stevens, VL, Owens, NE, Winton, EF, Kinkade, JM, and Merrill, AH, Jr: "Modulation of retinoic acid-induced differentiation of human leukemia (HL-60) cells by serum factors and sphinganine." Cancer Res 50, 222-226, 1990.
-
(1990)
Cancer Res
, vol.50
, pp. 222-226
-
-
Stevens, V.L.1
Owens, N.E.2
Winton, E.F.3
Kinkade, J.M.4
Merrill Jr., A.H.5
-
25
-
-
0028900748
-
Induction of apoptosis by sphingosine in human leukemic HL-60 cells: A possible endogenous modulator of apoptotic DNa fragmentation occurring during phorbol ester-induced differentiation
-
Ohta, H, Sweeney, EA, Masamune, A, Yatomi, Y, Hakomori, S-I, et al.: "Induction of apoptosis by sphingosine in human leukemic HL-60 cells: a possible endogenous modulator of apoptotic DNA fragmentation occurring during phorbol ester-induced differentiation." Cancer Res 55, 691-697, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 691-697
-
-
Ohta, H.1
Sweeney, E.A.2
Masamune, A.3
Yatomi, Y.4
Hakomori, S.-I.5
-
26
-
-
0029922118
-
Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells
-
Jarvis, WD, Fornari, FA, Traylor, RS, Martin, HA, Kramer, LB, et al.: "Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells." J Biol Chem 271, 8275-8284, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 8275-8284
-
-
Jarvis, W.D.1
Fornari, F.A.2
Traylor, R.S.3
Martin, H.A.4
Kramer, L.B.5
-
27
-
-
0027527545
-
Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide
-
Bielawska, A, Crane, HM, Liotta, DC, Obeid, LM, and Hannun, YA: "Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide." J Biol Chem 268, 26226-26232, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 26226-26232
-
-
Bielawska, A.1
Crane, H.M.2
Liotta, D.C.3
Obeid, L.M.4
Hannun, Y.A.5
-
28
-
-
0029127286
-
Role for ceramide as an endogenous mediator of fas-induced cytotoxicity
-
Tepper, CL, Jayadev, S, Liu, B, Bielawska, A, Wolff, RA, et al.: "Role for ceramide as an endogenous mediator of fas-induced cytotoxicity." Proc Natl Acad Sci USA 92, 8443-8447, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8443-8447
-
-
Tepper, C.L.1
Jayadev, S.2
Liu, B.3
Bielawska, A.4
Wolff, R.A.5
-
29
-
-
0028846952
-
Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells
-
Sawai, H, Okazaki, T, Yamamoto, H, Okano, H, Takeda, Y, et al.: "Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells." J Biol Chem 270, 27326-27331, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 27326-27331
-
-
Sawai, H.1
Okazaki, T.2
Yamamoto, H.3
Okano, H.4
Takeda, Y.5
-
30
-
-
0030066567
-
Ceramide induces apoptosis in cultured mesencephalic neurons
-
Brugg, B, Michel, PP, Agid, Y, and Ruberg, M: "Ceramide induces apoptosis in cultured mesencephalic neurons." J Neurochem 66, 733-739, 1996.
-
(1996)
J Neurochem
, vol.66
, pp. 733-739
-
-
Brugg, B.1
Michel, P.P.2
Agid, Y.3
Ruberg, M.4
-
31
-
-
0030000464
-
Stereospecific induction of apoptosis in U937 cells by N-octanoyl-sphingosine stereoisomers and N-octyl-sphingosine
-
Karasavvas, N, Erukulla, RK, Bittman, R, Lockshin, R, and Zakeri, Z: "Stereospecific induction of apoptosis in U937 cells by N-octanoyl-sphingosine stereoisomers and N-octyl-sphingosine." Eur J Biochem 236, 729-737, 1996.
-
(1996)
Eur J Biochem
, vol.236
, pp. 729-737
-
-
Karasavvas, N.1
Erukulla, R.K.2
Bittman, R.3
Lockshin, R.4
Zakeri, Z.5
-
32
-
-
0025756765
-
Cell membrane signaling as target in cancer therapy: Inhibitory effect of N,N-dimethyl and N,N,N-trimethyl sphingosine derivatives on in vitro and in vivo growth of human tumor cells in nude mice
-
Endo, K, Igarashi, Y, Nisar, M, Zhou, QH, and Hakomori, S-I: "Cell membrane signaling as target in cancer therapy: inhibitory effect of N,N-dimethyl and N,N,N-trimethyl sphingosine derivatives on in vitro and in vivo growth of human tumor cells in nude mice." Cancer Res 51, 1613-1618, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 1613-1618
-
-
Endo, K.1
Igarashi, Y.2
Nisar, M.3
Zhou, Q.H.4
Hakomori, S.-I.5
-
33
-
-
0030004270
-
Sphingosine and its methylated derivative N,N-dimethylsphingosine (MS) induce apoptosis in a variety of human cancer cell lines
-
Sweeney, EA, Sakakura, C, Shirahama, T, Masamune, A, Ohta, H, et al.: "Sphingosine and its methylated derivative N,N-dimethylsphingosine (MS) induce apoptosis in a variety of human cancer cell lines." Int J Cancer 66, 358-366, 1996.
-
(1996)
Int J Cancer
, vol.66
, pp. 358-366
-
-
Sweeney, E.A.1
Sakakura, C.2
Shirahama, T.3
Masamune, A.4
Ohta, H.5
-
34
-
-
0030071041
-
Suppression of Bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation
-
Sakakura, C, Sweeney, EA, Shirahama, T, Hakomori, S-I, and Igarashi, Y: "Suppression of Bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation." FEBS Lett 379, 177-180, 1996.
-
(1996)
FEBS Lett
, vol.379
, pp. 177-180
-
-
Sakakura, C.1
Sweeney, E.A.2
Shirahama, T.3
Hakomori, S.-I.4
Igarashi, Y.5
-
35
-
-
0028928295
-
Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor α, and ceramide
-
Chen, M, Quintans, J, Fuks, Z, Thompson, C, Kufe, DW, et al.: "Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor α, and ceramide." Cancer Res 55, 991-994, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 991-994
-
-
Chen, M.1
Quintans, J.2
Fuks, Z.3
Thompson, C.4
Kufe, D.W.5
-
36
-
-
0029834974
-
C-jun is a downstream target for ceramide-activated protein phosphatase in A431 cells
-
Reynes, JG, Robayna, IG, Delgado, PS, Gonzales, IH, Aguiar, JQ, et al.: "C-jun is a downstream target for ceramide-activated protein phosphatase in A431 cells." J Biol Chem 271, 21375-21380, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 21375-21380
-
-
Reynes, J.G.1
Robayna, I.G.2
Delgado, P.S.3
Gonzales, I.H.4
Aguiar, J.Q.5
-
37
-
-
0026007737
-
Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor α- and γ-interferon
-
Kim, MY, Linardic, C, Obeid, LM, and Hannun, YA: "Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor α- and γ-interferon." J Biol Chem 266, 484-489, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 484-489
-
-
Kim, M.Y.1
Linardic, C.2
Obeid, L.M.3
Hannun, Y.A.4
-
38
-
-
0026735066
-
Myc function and regulation
-
Marcu, KB, Bossone, SA, and Patel, AJ: "Myc function and regulation." Annu Rev Biochem 61, 809-860, 1992.
-
(1992)
Annu Rev Biochem
, vol.61
, pp. 809-860
-
-
Marcu, K.B.1
Bossone, S.A.2
Patel, A.J.3
-
39
-
-
0022839146
-
The role of sphingomyelin synthase and sphingomyelinase in 1,2-dimethylhydrazine-induced lipid alterations of rat coloniC plasma membranes
-
Dudeja, PK, Dahiya, R, and Brasitus, TA: "The role of sphingomyelin synthase and sphingomyelinase in 1,2-dimethylhydrazine-induced lipid alterations of rat coloniC plasma membranes." Biochim Biophys Acta 863, 309-312, 1986.
-
(1986)
Biochim Biophys Acta
, vol.863
, pp. 309-312
-
-
Dudeja, P.K.1
Dahiya, R.2
Brasitus, T.A.3
-
40
-
-
0029965928
-
Tumor cell resistance to apoptosis due to a defect in the activation of sphingomyelinase and the 24 kDa apoptotic protease
-
Wright, SC, Zheng, H, and Zhong, J: "Tumor cell resistance to apoptosis due to a defect in the activation of sphingomyelinase and the 24 kDa apoptotic protease." FASEB J 10, 325-332, 1996.
-
(1996)
FASEB J
, vol.10
, pp. 325-332
-
-
Wright, S.C.1
Zheng, H.2
Zhong, J.3
-
41
-
-
0022629488
-
Choline, phosphatidylcholine and sphingomyelin in human and bovine milk and infant formulas
-
Zeisel, SH, Char, D, and Shear, NF: "Choline, phosphatidylcholine and sphingomyelin in human and bovine milk and infant formulas." J Nutr 116, 50-58, 1986.
-
(1986)
J Nutr
, vol.116
, pp. 50-58
-
-
Zeisel, S.H.1
Char, D.2
Shear, N.F.3
-
42
-
-
0026725338
-
Meats and fish consumed in the American diet contain substantial amounts of ether-linked phospholipids
-
Blank, ML, Cress, EA, Smith, ZL, and Snyder, NF: "Meats and fish consumed in the American diet contain substantial amounts of ether-linked phospholipids." J Nutr 122, 1656-1661, 1992.
-
(1992)
J Nutr
, vol.122
, pp. 1656-1661
-
-
Blank, M.L.1
Cress, E.A.2
Smith, Z.L.3
Snyder, N.F.4
-
43
-
-
51249183390
-
Sphingolipids in immature and mature soybeans
-
Ohnishi, M, and Fujino, Y: "Sphingolipids in immature and mature soybeans." Lipids 17, 803-810, 1982.
-
(1982)
Lipids
, vol.17
, pp. 803-810
-
-
Ohnishi, M.1
Fujino, Y.2
|