메뉴 건너뛰기




Volumn 184, Issue 3, 2005, Pages 505-513

Improvement of metabolic state in an animal model of nutrition-dependent type 2 diabetes following treatment with S 23521, a new glucagon-like peptide 1 (GLP-1) analogue

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; HUMAN INSULIN; INSULIN; LEPTIN; S 23521; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 15844389890     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.1.05818     Document Type: Article
Times cited : (10)

References (42)
  • 1
    • 0032768616 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells
    • Buteau J, Roduit R, Susini S & Prentki M 1999 Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells. Diabetologia 42 856-864.
    • (1999) Diabetologia , vol.42 , pp. 856-864
    • Buteau, J.1    Roduit, R.2    Susini, S.3    Prentki, M.4
  • 2
    • 0035489990 scopus 로고    scopus 로고
    • Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation
    • Buteau J, Foisy S, Rhodes CJ, Carpenter L, Biden TJ & Prentki M 2001 Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation. Diabetes 50 2237-2243.
    • (2001) Diabetes , vol.50 , pp. 2237-2243
    • Buteau, J.1    Foisy, S.2    Rhodes, C.J.3    Carpenter, L.4    Biden, T.J.5    Prentki, M.6
  • 4
    • 0029056128 scopus 로고
    • Insulin deficiency and insulin resistance in the pathogenesis of NIDDM: Is a divorce possible?
    • Cerasi E 1995 Insulin deficiency and insulin resistance in the pathogenesis of NIDDM: is a divorce possible? Diabetologia 38 992-997.
    • (1995) Diabetologia , vol.38 , pp. 992-997
    • Cerasi, E.1
  • 5
    • 0038353630 scopus 로고    scopus 로고
    • The GLP-1 derivative NN2211 restores beta-cell sensitivity to glucose in type 2 diabetic patients after a single dose
    • Chang AM, Jakobsen G, Sturis J, Smith MJ, Bloem CJ, An B, Galecki A & Halter JB 2003 The GLP-1 derivative NN2211 restores beta-cell sensitivity to glucose in type 2 diabetic patients after a single dose. Diabetes 52 1786-1791.
    • (2003) Diabetes , vol.52 , pp. 1786-1791
    • Chang, A.M.1    Jakobsen, G.2    Sturis, J.3    Smith, M.J.4    Bloem, C.J.5    An, B.6    Galecki, A.7    Halter, J.B.8
  • 6
    • 0028953577 scopus 로고
    • Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo
    • Deacon CF, Johhnsen AH & Holst JJ 1995 Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo. Journal of Clinical Endocrinology and Metabolism 80 952-957.
    • (1995) Journal of Clinical Endocrinology and Metabolism , vol.80 , pp. 952-957
    • Deacon, C.F.1    Johhnsen, A.H.2    Holst, J.J.3
  • 8
    • 0033034807 scopus 로고    scopus 로고
    • Hyperglycemiainduced b cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes
    • Donath MY, Gross DJ, Cerasi E & Kaiser N 1999 Hyperglycemiainduced b cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes 48 738-744.
    • (1999) Diabetes , vol.48 , pp. 738-744
    • Donath, M.Y.1    Gross, D.J.2    Cerasi, E.3    Kaiser, N.4
  • 9
  • 10
    • 0035106978 scopus 로고    scopus 로고
    • Minireview: The glucagon-like peptides
    • Drucker DJ 2001 Minireview: the glucagon-like peptides. Endocrinology 142 521-527.
    • (2001) Endocrinology , vol.142 , pp. 521-527
    • Drucker, D.J.1
  • 11
    • 0036828227 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
    • Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U & Perfetti R 2002 Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 143 4397-4408.
    • (2002) Endocrinology , vol.143 , pp. 4397-4408
    • Farilla, L.1    Hui, H.2    Bertolotto, C.3    Kang, E.4    Bulotta, A.5    Di Mario, U.6    Perfetti, R.7
  • 12
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 promotes satiety and suppressesenergy intake in humans
    • Flint A, Raben A, Astrup A & Holst JJ 1998 Glucagon-like peptide 1 promotes satiety and suppressesenergy intake in humans. Journal of Clinical Investigation 101 515-520.
    • (1998) Journal of Clinical Investigation , vol.101 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Holst, J.J.4
  • 14
    • 0029091212 scopus 로고
    • Hyperproinsulinemia in the diabetic Psammomys obesus is a result of increased secretory demand on the B-cell
    • Gadot M, Ariav Y, Cerasi E, Kaiser N & Gross D 1995 Hyperproinsulinemia in the diabetic Psammomys obesus is a result of increased secretory demand on the B-cell. Endocrinology 136 4218-4223.
    • (1995) Endocrinology , vol.136 , pp. 4218-4223
    • Gadot, M.1    Ariav, Y.2    Cerasi, E.3    Kaiser, N.4    Gross, D.5
  • 15
    • 0026648674 scopus 로고
    • Identification of programmed cell death in vitro via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y & Ben Sasson SA 1992 Identification of programmed cell death in vitro via specific labeling of nuclear DNA fragmentation. Journal of Cell Biology 199 493-501.
    • (1992) Journal of Cell Biology , vol.199 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben Sasson, S.A.3
  • 16
    • 0030470658 scopus 로고    scopus 로고
    • Increased susceptibility of islets from diabetes-prone Psammomys obesus to the deleterious effects of chronic glucose exposure
    • Gross DJ, Leibowitz G, Cerasi E & Kaiser N 1996 Increased susceptibility of islets from diabetes-prone Psammomys obesus to the deleterious effects of chronic glucose exposure. Endocrinology 137 5610-5615.
    • (1996) Endocrinology , vol.137 , pp. 5610-5615
    • Gross, D.J.1    Leibowitz, G.2    Cerasi, E.3    Kaiser, N.4
  • 18
    • 0036721246 scopus 로고    scopus 로고
    • Transfection of pancreatic-derived beta-cells with a minigene encoding for human glucagon-like peptide-1 regulates glucose-dependent insulin synthesis and secretion
    • Hui H, Yu R, Bousquet C & Perfetti R 2002 Transfection of pancreatic-derived beta-cells with a minigene encoding for human glucagon-like peptide-1 regulates glucose-dependent insulin synthesis and secretion. Endocrinology 143 3529-3539.
    • (2002) Endocrinology , vol.143 , pp. 3529-3539
    • Hui, H.1    Yu, R.2    Bousquet, C.3    Perfetti, R.4
  • 20
    • 0037283601 scopus 로고    scopus 로고
    • The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
    • Kahn SE 2003 The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. Diabetologia 46 3-19.
    • (2003) Diabetologia , vol.46 , pp. 3-19
    • Kahn, S.E.1
  • 22
    • 0022482184 scopus 로고
    • Characterization of stages in development of obesity-diabetes syndrome in the sand rat (Psammomys obesus)
    • Kalderon B, Gutman A, Levy E, Shafrir E & Adler JH 1986 Characterization of stages in development of obesity-diabetes syndrome in the sand rat (Psammomys obesus). Diabetes 35 717-723.
    • (1986) Diabetes , vol.35 , pp. 717-723
    • Kalderon, B.1    Gutman, A.2    Levy, E.3    Shafrir, E.4    Adler, J.H.5
  • 23
    • 0035516188 scopus 로고    scopus 로고
    • Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats
    • Larsen PJ, Fledelius C, Knudsen LB & Tang-Christensen M 2001 Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats. Diabetes 50 2530-2539.
    • (2001) Diabetes , vol.50 , pp. 2530-2539
    • Larsen, P.J.1    Fledelius, C.2    Knudsen, L.B.3    Tang-Christensen, M.4
  • 29
    • 0030447883 scopus 로고    scopus 로고
    • Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells
    • Marshak S, Totary H, Cerasi E & Melloul D 1996 Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells. PNAS 93 15057-15062.
    • (1996) PNAS , vol.93 , pp. 15057-15062
    • Marshak, S.1    Totary, H.2    Cerasi, E.3    Melloul, D.4
  • 30
    • 0037667613 scopus 로고    scopus 로고
    • Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes
    • Meier JJ, Gallwitz B, Salmen S, Goetze O, Holst JJ, Schmidt WE & Nauck MA 2003 Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism 88 2719-2725.
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , pp. 2719-2725
    • Meier, J.J.1    Gallwitz, B.2    Salmen, S.3    Goetze, O.4    Holst, J.J.5    Schmidt, W.E.6    Nauck, M.A.7
  • 32
    • 15844429394 scopus 로고    scopus 로고
    • Exendin-4 upregulates expression of PDX-1 and hastens differentiation and maturation of human fetal pancreatic B cells
    • Movassat J, Lopez AD, Beattie GB & Hayek A 2001 Exendin-4 upregulates expression of PDX-1 and hastens differentiation and maturation of human fetal pancreatic B cells. Diabetes 50 (Suppl 2) A341.
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 2
    • Movassat, J.1    Lopez, A.D.2    Beattie, G.B.3    Hayek, A.4
  • 33
    • 0032999921 scopus 로고    scopus 로고
    • Interaction between genetic and dietary factors determines β-cell function in Psammomys obesus, an animal model of type 2 diabetes
    • Nesher R, Gross DJ, Donath MY, Cerasi E & Kaiser N 1999 Interaction between genetic and dietary factors determines β-cell function in Psammomys obesus, an animal model of type 2 diabetes. Diabetes 48 731-737.
    • (1999) Diabetes , vol.48 , pp. 731-737
    • Nesher, R.1    Gross, D.J.2    Donath, M.Y.3    Cerasi, E.4    Kaiser, N.5
  • 34
    • 0038522555 scopus 로고    scopus 로고
    • Specific and combined effects of insulin and glucose on functional pancreatic β-cell mass in vivo in adult rats
    • Paris M, Bernard-Kragar C, Berthault MF, Bouwens L & Ktorza A 2003 Specific and combined effects of insulin and glucose on functional pancreatic β-cell mass in vivo in adult rats. Endocrinology 144 2717-2727.
    • (2003) Endocrinology , vol.144 , pp. 2717-2727
    • Paris, M.1    Bernard-Kragar, C.2    Berthault, M.F.3    Bouwens, L.4    Ktorza, A.5
  • 35
    • 0034522773 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats
    • Perfetti R, Zhou J, Doyle ME & Egan JM 2000 Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats. Endocrinology 141 4600-4605.
    • (2000) Endocrinology , vol.141 , pp. 4600-4605
    • Perfetti, R.1    Zhou, J.2    Doyle, M.E.3    Egan, J.M.4
  • 38
    • 0036312680 scopus 로고    scopus 로고
    • Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4
    • Tourrel C, Bailbe D, Lacorne M, Meile MJ, Kergoat M & Portha B 2002 Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4. Diabetes 51 1443-1452.
    • (2002) Diabetes , vol.51 , pp. 1443-1452
    • Tourrel, C.1    Bailbe, D.2    Lacorne, M.3    Meile, M.J.4    Kergoat, M.5    Portha, B.6
  • 39
    • 0036381989 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
    • Wang Q & Brubaker PL, 2002 Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice. Diabetologia 45 1263-1273.
    • (2002) Diabetologia , vol.45 , pp. 1263-1273
    • Wang, Q.1    Brubaker, P.L.2
  • 40
    • 0033305746 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 regulates the beta cell transcription factor PDX-1 in insulinoma cells
    • Wang X, Cahill CM, Pineyro MA, Zhou J, Doyle ME & Egan JM 1999 Glucagon-like peptide-1 regulates the beta cell transcription factor PDX-1 in insulinoma cells. Endocrinology 140 4904-4907.
    • (1999) Endocrinology , vol.140 , pp. 4904-4907
    • Wang, X.1    Cahill, C.M.2    Pineyro, M.A.3    Zhou, J.4    Doyle, M.E.5    Egan, J.M.6
  • 41
    • 0035046251 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism
    • Wang X, Zhou J, Doyle ME & Egan JM 2001 Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism. Endocrinology 142 1820-1827.
    • (2001) Endocrinology , vol.142 , pp. 1820-1827
    • Wang, X.1    Zhou, J.2    Doyle, M.E.3    Egan, J.M.4
  • 42
    • 0033513455 scopus 로고    scopus 로고
    • Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
    • Xu G, Stoffers DA, Habener JF & Bonner-Weir S 1999 Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes 48 2270-2276.
    • (1999) Diabetes , vol.48 , pp. 2270-2276
    • Xu, G.1    Stoffers, D.A.2    Habener, J.F.3    Bonner-Weir, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.