-
2
-
-
0025142898
-
Natural history of β-cell dysfunction in NIDDM
-
Leahy JL 1990 Natural history of β-cell dysfunction in NIDDM. Diabetes Care 13:992-1010
-
(1990)
Diabetes Care
, vol.13
, pp. 992-1010
-
-
Leahy, J.L.1
-
3
-
-
0002417577
-
Aetiology of type II diabetes
-
Ashcroft FM, Ashcroft SJH (ed) Oxford University Press, Oxford
-
Cerasi E 1992 Aetiology of type II diabetes. In: Ashcroft FM, Ashcroft SJH (ed) Insulin: Molecular Biology to Pathology. Oxford University Press, Oxford, pp 347-392
-
(1992)
Insulin: Molecular Biology to Pathology
, pp. 347-392
-
-
Cerasi, E.1
-
4
-
-
0023634652
-
Disproportionate elevation of immunoreactive proinsulin in type 2 (non-insulin-dependent) diabetes mellitus and in experimental insulin resistance
-
Ward WK, LaCava EC, Paquette TL, Beard JC, Wallum BJ, Porte Jr D 1987 Disproportionate elevation of immunoreactive proinsulin in type 2 (non-insulin-dependent) diabetes mellitus and in experimental insulin resistance. Diabetologia 30:698-702
-
(1987)
Diabetologia
, vol.30
, pp. 698-702
-
-
Ward, W.K.1
LaCava, E.C.2
Paquette, T.L.3
Beard, J.C.4
Wallum, B.J.5
Porte Jr., D.6
-
5
-
-
0024214959
-
Preferential release of proinsulin relative to insulin in non-insulin-dependent diabetes mellitus
-
Copenh
-
Deacon CF, Schleser MS, Ballmann M, Willms B, Conlon JM, Creutzfeldt W 1988 Preferential release of proinsulin relative to insulin in non-insulin-dependent diabetes mellitus. Acta Endocrinol (Copenh) 119:549-554
-
(1988)
Acta Endocrinol
, vol.119
, pp. 549-554
-
-
Deacon, C.F.1
Schleser, M.S.2
Ballmann, M.3
Willms, B.4
Conlon, J.M.5
Creutzfeldt, W.6
-
6
-
-
0024494876
-
Insulin deficiency in non-insulin-dependent diabetes
-
Temple RC, Carrington CA, Luzio SD, Owens DR, Schneider AE, Sobey WJ, Hales CN 1989 Insulin deficiency in non-insulin-dependent diabetes. Lancet 1:293-295
-
(1989)
Lancet
, vol.1
, pp. 293-295
-
-
Temple, R.C.1
Carrington, C.A.2
Luzio, S.D.3
Owens, D.R.4
Schneider, A.E.5
Sobey, W.J.6
Hales, C.N.7
-
7
-
-
0027386638
-
Normal proinsulin responses to glucose in mild type II subjects with subnormal insulin response
-
Levy JC, Clark PM, Hales CN, Turner RC 1993 Normal proinsulin responses to glucose in mild type II subjects with subnormal insulin response. Diabetes 42:162-169
-
(1993)
Diabetes
, vol.42
, pp. 162-169
-
-
Levy, J.C.1
Clark, P.M.2
Hales, C.N.3
Turner, R.C.4
-
8
-
-
0015413087
-
Effect of chronic sulfonylurea therapy on plasma insulin and proinsulin levels
-
Duckworth WC, Solomon SS, Kitabchi AE 1972 Effect of chronic sulfonylurea therapy on plasma insulin and proinsulin levels. J Clin Endocrinol Metab 35:585-591
-
(1972)
J Clin Endocrinol Metab
, vol.35
, pp. 585-591
-
-
Duckworth, W.C.1
Solomon, S.S.2
Kitabchi, A.E.3
-
9
-
-
0017761172
-
Circulating proinsulin in patients with maturity onset diabetes
-
Mako SE, Starr JI, Rubenstein AH 1977 Circulating proinsulin in patients with maturity onset diabetes. Am J Med 63:865-869
-
(1977)
Am J Med
, vol.63
, pp. 865-869
-
-
Mako, S.E.1
Starr, J.I.2
Rubenstein, A.H.3
-
10
-
-
0018899699
-
Increase in insulin response after treatment of overt maturity-onset diabetes is independent of the mode of treatment
-
Kosaka K, Kuzuya T, Akanuma Y, Hagura R 1980 Increase in insulin response after treatment of overt maturity-onset diabetes is independent of the mode of treatment. Diabetologia 18:23-28
-
(1980)
Diabetologia
, vol.18
, pp. 23-28
-
-
Kosaka, K.1
Kuzuya, T.2
Akanuma, Y.3
Hagura, R.4
-
11
-
-
0019942238
-
Improvement of insulin secretion but not insulin resistance after short term control of plasma glucose in obese type II diabetics
-
Hidaka H, Nagulesparan M, Klimes I, Clark R, Sasaki H, Aronoff SL, Vasquez B, Rubenstein AH, Unger RH 1982 Improvement of insulin secretion but not insulin resistance after short term control of plasma glucose in obese type II diabetics. J Clin Endocrinol Metab 54:217-222
-
(1982)
J Clin Endocrinol Metab
, vol.54
, pp. 217-222
-
-
Hidaka, H.1
Nagulesparan, M.2
Klimes, I.3
Clark, R.4
Sasaki, H.5
Aronoff, S.L.6
Vasquez, B.7
Rubenstein, A.H.8
Unger, R.H.9
-
12
-
-
0023777821
-
Improved beta-cell function after intensive insulin treatment in severe non-insulin-dependent diabetes
-
Copenh
-
Glaser B, Leibovich G, Nesher R, Hartling S, Binder C, Cerasi E 1988 Improved beta-cell function after intensive insulin treatment in severe non-insulin-dependent diabetes. Acta Endocrinol (Copenh) 118:365-373
-
(1988)
Acta Endocrinol
, vol.118
, pp. 365-373
-
-
Glaser, B.1
Leibovich, G.2
Nesher, R.3
Hartling, S.4
Binder, C.5
Cerasi, E.6
-
13
-
-
0024493106
-
Effect of dietary treatment on serum insulin and proinsulin response in newly diagnosed NIDDM
-
Yoshioka N, Kuzuya T, Matsuda A, Iwamoto Y 1989 Effect of dietary treatment on serum insulin and proinsulin response in newly diagnosed NIDDM. Diabetes 38:262-266
-
(1989)
Diabetes
, vol.38
, pp. 262-266
-
-
Yoshioka, N.1
Kuzuya, T.2
Matsuda, A.3
Iwamoto, Y.4
-
14
-
-
0028085339
-
Hyperproinsulinemia and insulin deficiency in the diabetic Psammomys obesus
-
Gadot M, Leibowitz G, Shafrir E, Cerasi E, Gross DJ, Kaiser N 1994 Hyperproinsulinemia and insulin deficiency in the diabetic Psammomys obesus. Endocrinology 135:610-616
-
(1994)
Endocrinology
, vol.135
, pp. 610-616
-
-
Gadot, M.1
Leibowitz, G.2
Shafrir, E.3
Cerasi, E.4
Gross, D.J.5
Kaiser, N.6
-
15
-
-
0029091212
-
Hyperproinsulinemia in the diabetic Psammomys obesus is a result of increased secretory demand on the B-cell
-
Gadot M, Ariav Y, Cerasi E, Kaiser N, Gross DJ 1995 Hyperproinsulinemia in the diabetic Psammomys obesus is a result of increased secretory demand on the B-cell. Endocrinology 1995:4218-4223
-
(1995)
Endocrinology
, vol.1995
, pp. 4218-4223
-
-
Gadot, M.1
Ariav, Y.2
Cerasi, E.3
Kaiser, N.4
Gross, D.J.5
-
16
-
-
0025736943
-
Relative hypersecretion of proinsulin in rat model of NIDDM
-
Leahy JL, Halban PA, Weir GC 1991 Relative hypersecretion of proinsulin in rat model of NIDDM. Diabetes 40:985-989
-
(1991)
Diabetes
, vol.40
, pp. 985-989
-
-
Leahy, J.L.1
Halban, P.A.2
Weir, G.C.3
-
17
-
-
0027389774
-
Increased proinsulin/insulin ratio in pancreas extracts of hyperglycemic rats
-
Leahy JL 1993 Increased proinsulin/insulin ratio in pancreas extracts of hyperglycemic rats. Diabetes 42:22-27
-
(1993)
Diabetes
, vol.42
, pp. 22-27
-
-
Leahy, J.L.1
-
18
-
-
0028912883
-
Increased secretory demand rather than a detect in the proinsulin conversion mechanism causes hyperproinsuhnemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus
-
Alarcon C, Leahy JL, Schuppin GT, Rhodes CJ 1995 Increased secretory demand rather than a detect in the proinsulin conversion mechanism causes hyperproinsuhnemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus. J Clin Invest 95:1032-1039
-
(1995)
J Clin Invest
, vol.95
, pp. 1032-1039
-
-
Alarcon, C.1
Leahy, J.L.2
Schuppin, G.T.3
Rhodes, C.J.4
-
19
-
-
0024271685
-
Reduction in glycemic potentiation. Sensitive indicator of β-cell loss in partially pancreatectomized clogs
-
Ward WK, Wallum BJ, Beard JC, Taborsky Jr GJ, Porte Jr D 1988 Reduction in glycemic potentiation. Sensitive indicator of β-cell loss in partially pancreatectomized clogs. Diabetes 37:723-729
-
(1988)
Diabetes
, vol.37
, pp. 723-729
-
-
Ward, W.K.1
Wallum, B.J.2
Beard, J.C.3
Taborsky Jr., G.J.4
Porte Jr., D.5
-
20
-
-
0026043872
-
Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin
-
Nauck MA, Siegel EG, Creutzfeldt W 1991 Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin. Pancreas 6:645-652
-
(1991)
Pancreas
, vol.6
, pp. 645-652
-
-
Nauck, M.A.1
Siegel, E.G.2
Creutzfeldt, W.3
-
21
-
-
0023758721
-
Monolayer culture of adult rat pancreatic islets on extracellular matrix: Long term maintenance of differentiated B-cell function
-
Kaiser N, Corcos AP, Tur-Sinai A, Ariav Y, Cerasi E 1988 Monolayer culture of adult rat pancreatic islets on extracellular matrix: long term maintenance of differentiated B-cell function. Endocrinology 123:834-840
-
(1988)
Endocrinology
, vol.123
, pp. 834-840
-
-
Kaiser, N.1
Corcos, A.P.2
Tur-Sinai, A.3
Ariav, Y.4
Cerasi, E.5
-
22
-
-
0026091234
-
Monolayer culture of adult rat pancreatic islets on extracellular matrix: Modulation of B-cell function by chronic exposure to high glucose
-
Kaiser N, Corcos AP, Sarel I, Cerasi E 1991 Monolayer culture of adult rat pancreatic islets on extracellular matrix: modulation of B-cell function by chronic exposure to high glucose. Endocrinology 129:2067-2076
-
(1991)
Endocrinology
, vol.129
, pp. 2067-2076
-
-
Kaiser, N.1
Corcos, A.P.2
Sarel, I.3
Cerasi, E.4
-
23
-
-
0027733877
-
Psammomys obesus of the Jerusalem colony: A model for nutritionally induced non-insulin-dependent diabetes
-
Shafrir E, Gutman A 1993 Psammomys obesus of the Jerusalem colony: a model for nutritionally induced non-insulin-dependent diabetes. J Basic Clin Physiol Pharmacol 4:83-99
-
(1993)
J Basic Clin Physiol Pharmacol
, vol.4
, pp. 83-99
-
-
Shafrir, E.1
Gutman, A.2
-
24
-
-
0014042613
-
Method for the isolation of intact islets of Langerhans from rat pancreas
-
Lacy PE, Kostianovsky M 1967 Method for the isolation of intact islets of Langerhans from rat pancreas. Diabetes 16:35-34
-
(1967)
Diabetes
, vol.16
, pp. 35-134
-
-
Lacy, P.E.1
Kostianovsky, M.2
-
25
-
-
0024245270
-
Oxidation of rat insulin II, but not I, leads to anomalous elution profiles upon HPLC analysis of insulin-related peptides
-
Gross DJ, Skvorak A, Hendrick G, Weir G, Villa-Komaroff L, Halban P 1988 Oxidation of rat insulin II, but not I, leads to anomalous elution profiles upon HPLC analysis of insulin-related peptides. FEBS Lett 241:205-208
-
(1988)
FEBS Lett
, vol.241
, pp. 205-208
-
-
Gross, D.J.1
Skvorak, A.2
Hendrick, G.3
Weir, G.4
Villa-Komaroff, L.5
Halban, P.6
-
26
-
-
0030040425
-
Hyperproinsulinemia is associated with increased β-cell demand after hemipancreatectomy in humans
-
Seaquist ER, Kahn SE, Clark PM, Hales CN, Porte Jr D, Robertson RP 1996 Hyperproinsulinemia is associated with increased β-cell demand after hemipancreatectomy in humans. J Clin Invest 97:455-460
-
(1996)
J Clin Invest
, vol.97
, pp. 455-460
-
-
Seaquist, E.R.1
Kahn, S.E.2
Clark, P.M.3
Hales, C.N.4
Porte Jr., D.5
Robertson, R.P.6
-
27
-
-
0023109065
-
The effects of biosynthetic human proinsulin on carbohydrate metabolism in non-insulin-dependent diabetes mellitus
-
Glauber HS, Henry RR, Wallace P, Frank BH, Galloway JA, Cohen RM, Olefsky JM 1987 The effects of biosynthetic human proinsulin on carbohydrate metabolism in non-insulin-dependent diabetes mellitus. N Engl J Med 316:443-449
-
(1987)
N Engl J Med
, vol.316
, pp. 443-449
-
-
Glauber, H.S.1
Henry, R.R.2
Wallace, P.3
Frank, B.H.4
Galloway, J.A.5
Cohen, R.M.6
Olefsky, J.M.7
-
28
-
-
0023267332
-
Insulin deficiency and insulin resistance in tvpe 2 (non-insulin-dependent) diabetes: Quantitative contributions of pancreatic and peripheral responses to glucose homeostasis
-
Nesher R, Della Casa L, Litvin Y, Sinai J, Del Rio G, Pevsner B, Wax Y, Cerasi E 1987 Insulin deficiency and insulin resistance in tvpe 2 (non-insulin-dependent) diabetes: quantitative contributions of pancreatic and peripheral responses to glucose homeostasis. Eur J Clin Invest 17:266-274
-
(1987)
Eur J Clin Invest
, vol.17
, pp. 266-274
-
-
Nesher, R.1
Della Casa, L.2
Litvin, Y.3
Sinai, J.4
Del Rio, G.5
Pevsner, B.6
Wax, Y.7
Cerasi, E.8
-
29
-
-
0022578602
-
Abnormalities of insulin responses after ambient and previous exposure to glucose in streptozotocin-diabetes and dexamethasone-treated rats. Role of hyperglycemia and increased B-cell demands
-
Grill V, Rundfeldt M 1986 Abnormalities of insulin responses after ambient and previous exposure to glucose in streptozotocin-diabetes and dexamethasone-treated rats. Role of hyperglycemia and increased B-cell demands. Diabetes 35:44-51
-
(1986)
Diabetes
, vol.35
, pp. 44-51
-
-
Grill, V.1
Rundfeldt, M.2
-
30
-
-
0025880271
-
Beta-cell dysfunction in hyperglycaemic rat models: Recovery of glucose-induced insulin secretion with lowering of the ambient glucose level
-
Leahy JL, Weir GC 1991 Beta-cell dysfunction in hyperglycaemic rat models: recovery of glucose-induced insulin secretion with lowering of the ambient glucose level. Diabetologia 34:640-647
-
(1991)
Diabetologia
, vol.34
, pp. 640-647
-
-
Leahy, J.L.1
Weir, G.C.2
-
31
-
-
0025989824
-
Hyperin-sulinaemia in obesity is not accompanied by an increase in serum proinsulin/insulin ratio in groups of human subjects with and without glucose intolerance
-
Shiraishi I, Iwamoto Y, Kuzuya T, Matsuda A, Kumakura S 1991 Hyperin-sulinaemia in obesity is not accompanied by an increase in serum proinsulin/insulin ratio in groups of human subjects with and without glucose intolerance. Diabetologia 34:737-741
-
(1991)
Diabetologia
, vol.34
, pp. 737-741
-
-
Shiraishi, I.1
Iwamoto, Y.2
Kuzuya, T.3
Matsuda, A.4
Kumakura, S.5
-
32
-
-
0027449197
-
A second pathway for regeneration of the adult exocrine and endocrine pancreas: A possible recapitulation of embryonic development
-
Bonner-Weir S, Baxter LA, Schuppin GT, Smith FE 1993 A second pathway for regeneration of the adult exocrine and endocrine pancreas: a possible recapitulation of embryonic development. Diabetes 42:1715-1720
-
(1993)
Diabetes
, vol.42
, pp. 1715-1720
-
-
Bonner-Weir, S.1
Baxter, L.A.2
Schuppin, G.T.3
Smith, F.E.4
|