Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells

Journal of Biological Chemistry

Volumn 279, Issue 9, 2004, Pages 7598-7605

  Kaeser, Matthias D ^a   Pebernard, Stephanie ^a   Iggo, Richard D ^a  

^a SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; FEEDBACK; GENES; PHYSIOLOGY; VECTORS;

FIBROBLASTS; GENOTOXIC STRESS;

TUMORS;

DOXORUBICIN; FLUOROURACIL; LENTIVIRUS VECTOR; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MDM2; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE G1 PHASE; COLON CANCER; DNA REPAIR; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN SYNTHESIS REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; COLONIC NEOPLASMS; DNA DAMAGE; DOXORUBICIN; DRUG STABILITY; FIBROBLASTS; FLOW CYTOMETRY; FLUOROURACIL; GENE EXPRESSION; GENETIC VECTORS; HUMANS; IMMUNOBLOTTING; LENTIVIRUS; LUNG; MICE; MUTAGENESIS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERINE; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

LENTIVIRUS;

EID: 1542350145     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M311732200     Document Type: Article

References (55)

1. Vogelstein, B., Lane, D., and Levine, A. J. (2000) Nature 408, 307-310
2. Zhao, R., Gish, K., Murphy, M., Yin, Y., Notterman, D., Hoffman, W. H., Tom, E., Mack, D. H., and Levine, A. J. (2000) Genes Dev. 14, 981-993
3. Mihara, M., Erster, S., Zaika, A., Petrenko, O., Chittenden, T., Pancoska, P., and Moll, U. M. (2003) Mol. Cell 11, 577-590
4. Weber, J. D., Taylor, L. J., Roussel, M. F., Sherr, C. J., and Bar-Sagi, D. (1999) Nat. Cell Biol. 1, 20-26
5. Sherr, C. J., and Weber, J. D. (2000) Curr. Opin. Genet. Dev. 10, 94-99
6. Wu, X., Bayle, J. H., Olson, D., and Levine, A. J. (1993) Genes Dev. 7, 1126-1132
7. Kubbutat, M. H., Jones, S. N., and Vousden, K. H. (1997) Nature 387, 299-303
8. Haupt, Y., Maya, R., Kazaz, A., and Oren, M. (1997) Nature 387, 296-299
9. Honda, R., and Yasuda, H. (1999) EMBO J. 18, 22-27
10. Grossman, S. R., Deato, M. E., Brignone, C., Chan, H. M., Kung, A. L., Tagami, H., Nakatani, Y., and Livingston, D. M. (2003) Science 300, 342-344
11. Anderson, C. W., and Appella, E. (2003) in Handbook of Cell Signaling (Bradshaw, R. A., and Dennis, E., eds) Vol 3, pp. 237-247, Academic Press, New York
12. Dumaz, N., and Meek, D. W. (1999) EMBO J. 18, 7002-7010
13. Chehab, N. H., Malikzay, A., Appel, M., and Halazonetis, T. D. (2000) Genes Dev. 14, 278-288
14. Sakaguchi, K., Herrera, J. E., Saito, S., Miki, T., Bustin, M., Vassilev, A., Anderson, C. W., and Appella, E. (1998) Genes Dev. 12, 2831-2841
15. Gu, W., and Roeder, R. G. (1997) Cell 90, 595-606
16. Barlev, N. A., Liu, L., Chehab, N. H., Mansfield, K., Harris, K. G., Halazonetis, T. D., and Berger, S. L. (2001) Mol. Cell 8, 1243-1254
17. Blattner, C., Tobiasch, E., Litfen, M., Rahmsdorf, H. J., and Herrlich, P. (1999) Oncogene 18, 1723-1732
18. Ashcroft, M., Kubbutat, M. H., and Vousden, K. H. (1999) Mol. Cell. Biol. 19, 1751-1758
19. Saito, S., Yamaguchi, H., Higashimoto, Y., Chao, C., Xu, Y., Fornace, A. J., Jr., Appella, E., and Anderson, C. W. (2003) J. Biol. Chem. 278, 37536-37544
20. Chao, C., Hergenhahn, M., Kaeser, M. D., Wu, Z., Saito, S., Iggo, R., Hollstein, M., Appella, E., and Xu, Y. (2003) J. Biol. Chem. 278, 41028-41033
21. Wu, Z., Earle, J., Saito, S., Anderson, C. W., Appella, E., and Xu, Y. (2002) Mol. Cell. Biol. 22, 2441-2449
22. Bunz, F., Hwang, P. M., Torrance, C., Waldman, T., Zhang, Y., Dillehay, L., Williams, J., Lengauer, C., Kinzler, K. W., and Vogelstein, B. (1999) J. Clin. Invest. 104, 263-269
23. Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W., and Vogelstein, B. (1998) Science 282, 1497-1501
24. Vojtesek, B., Bartek, J., Midgley, C. A., and Lane, D. P. (1992) J. Immunol. Methods 151, 237-244
25. Saller, E., Tom, E., Brunori, M., Otter, M., Estreicher, A., Mack, D. H., and Iggo, R. (1999) EMBO J. 18, 4424-4437
26. Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A., and Speleman, F. (2002) Genome Biol. 3, 1-12
27. Naldini, L., Blomer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., and Trono, D. (1996) Science 272, 263-267
28. Bridge, A. J., Pebernard, S., Ducraux, A., Nicoulaz, A. L., and Iggo, R. (2003) Nat. Genet. 34, 263-264
29. Morgenstern, J. P., and Land, H. (1990) Nucleic Acids Res. 18, 3587-3596
30. Brummelkamp, T. R., Bernards, R., and Agami, R. (2002) Science 296, 550-553
31. Dumont, P., Leu, J. I., Della Pietra, A. C., 3rd, George, D. L., and Murphy, M. (2003) Nat. Genet. 33, 357-365
32. Yu, J., Zhang, L., Hwang, P. M., Kinzler, K. W., and Vogelstein, B. (2001) Mol. Cell 7, 673-682
33. Nakano, K., and Vousden, K. H. (2001) Mol. Cell 7, 683-694
34. Han, J., Flemington, C., Houghton, A. B., Gu, Z., Zambetti, G. P., Lutz, R. J., Zhu, L., and Chittenden, T. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 11318-11323
35. Yu, J., Wang, Z., Kinzler, K. W., Vogelstein, B., and Zhang, L. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 1931-1936
36. Chehab, N. H., Malikzay, A., Stavridi, E. S., and Halazonetis, T. D. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 13777-13782
37. Maya, R., Balass, M., Kim, S. T., Shkedy, D., Leal, J. F., Shifman, O., Moas, M., Buschmann, T., Ronai, Z., Shiloh, Y., Kastan, M. B., Katzir, E., and Oren, M. (2001) Genes Dev. 15, 1067-1077
38. Blattner, C., Hay, T., Meek, D. W., and Lane, D. P. (2002) Mol. Cell. Biol. 22, 6170-6182
39. Lin, J., Chen, J., Elenbaas, B., and Levine, A. J. (1994) Genes Dev. 8, 1235-1246
40. Jimenez, G. S., Nister, M., Stommel, J. M., Beeche, M., Barcarse, E. A., Zhang, X. Q., O'Gorman, S., and Wahl, G. M. (2000) Nat. Genet. 26, 37-43
41. Leng, R. P., Lin, Y., Ma, W., Wu, H., Lemmers, B., Chung, S., Parant, J. M., Lozano, G., Hakem, R., and Benchimol, S. (2003) Cell 112, 779-791
42. Zhang, L., Yu, J., Park, B. H., Kinzler, K. W., and Vogelstein, B. (2000) Science 290, 989-992
43. Hwang, P. M., Bunz, F., Yu, J., Rago, C., Chan, T. A., Murphy, M. P., Kelso, G. F., Smith, R. A., Kinzler, K. W., and Vogelstein, B. (2001) Nat. Med. 7, 1111-1117
44. Jallepalli, P. V., Lengauer, C., Vogelstein, B., and Bunz, F. (2003) J. Biol. Chem. 278, 20475-20479
45. Shieh, S. Y., Ahn, J., Tamai, K., Taya, Y., and Prives, C. (2000) Genes Dev. 14, 289-300
46. Unger, T., Juven-Gershon, T., Moallem, E., Berger, M., Vogt Sionov, R., Lozano, G., Oren, M., and Haupt, Y. (1999) EMBO J. 18, 1805-1814
47. Bottger, A., Bottger, V., Sparks, A., Liu, W. L., Howard, S. F., and Lane, D. P. (1997) Curr. Biol. 7, 860-869
48. Blaydes, J. P., Gire, V., Rowson, J. M., and Wynford-Thomas, D. (1997) Oncogene 14, 1859-1868
49. Midgley, C. A., Desterro, J. M., Saville, M. K., Howard, S., Sparks, A., Hay, R. T., and Lane, D. P. (2000) Oncogene 19, 2312-2323
50. Chene, P., Fuchs, J., Bohn, J., Garcia-Echeverria, C., Furet, P., and Fabbro, D. (2000) J. Mol. Biol. 299, 245-253
51. Burri, N., Shaw, P., Bouzourene, H., Sordat, I., Sordat, B., Gillet, M., Schorderet, D., Bosman, F. T., and Chaubert, P. (2001) Lab. Invest. 81, 217-229
52. Bech-Otschir, D., Kraft, R., Huang, X., Henklein, P., Kapelari, B., Pollmann, C., and Dubiel, W. (2001) EMBO J. 20, 1630-1639
53. Buschmann, T., Potapova, O., Bar-Shira, A., Ivanov, V. N., Fuchs, S. Y., Henderson, S., Fried, V. A., Minamoto, T., Alarcon-Vargas, D., Pincus, M. R., Gaarde, W. A., Holbrook, N. J., Shiloh, Y., and Ronai, Z. (2001) Mol. Cell. Biol. 21, 2743-2754
54. Unger, T., Sionov, R. V., Moallem, E., Yee, C. L., Howley, P. M., Oren, M., and Haupt, Y. (1999) Oncogene 18, 3205-3212
55. Kaeser, M. D., and Iggo, R. D. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 95-100