-
1
-
-
0033826764
-
Iron regulatory proteins and the molecular control of mammalian iron metabolism
-
R.S. Eisenstein Iron regulatory proteins and the molecular control of mammalian iron metabolism Annu. Rev. Nutr. 20 2000 627 662
-
(2000)
Annu. Rev. Nutr.
, vol.20
, pp. 627-662
-
-
Eisenstein, R.S.1
-
2
-
-
0034531651
-
Iron regulatory proteins in pathobiology
-
G. Cairo, and A. Pietrangelo Iron regulatory proteins in pathobiology Biochem. J. 352 2000 241 250
-
(2000)
Biochem. J.
, vol.352
, pp. 241-250
-
-
Cairo, G.1
Pietrangelo, A.2
-
3
-
-
0035138456
-
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
-
T. LaVaute, S. Smith, S. Cooperman, K. Iwai, W. Land, E. Meyron-Holtz, S.K. Drake, G. Miller, M. Abu-Asab, M. Tsokos, R. Switzer III, A. Grinberg, P. Love, N. Tresser, and T.A. Rouault Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice Nat. Genet. 27 2001 209 214
-
(2001)
Nat. Genet.
, vol.27
, pp. 209-214
-
-
Lavaute, T.1
Smith, S.2
Cooperman, S.3
Iwai, K.4
Land, W.5
Meyron-Holtz, E.6
Drake, S.K.7
Miller, G.8
Abu-Asab, M.9
Tsokos, M.10
Switzer III, R.11
Grinberg, A.12
Love, P.13
Tresser, N.14
Rouault, T.A.15
-
4
-
-
0028982262
-
Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome
-
B. Guo, J.D. Phillips, Y. Yu, and E.A. Leibold Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome J. Biol. Chem. 270 1995 21645 21651
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21645-21651
-
-
Guo, B.1
Phillips, J.D.2
Yu, Y.3
Leibold, E.A.4
-
5
-
-
0033582451
-
Hypoxia post-translationally activates iron-regulatory protein 2
-
E.S. Hanson, L.M. Foot, and E.A. Leibold Hypoxia post-translationally activates iron-regulatory protein 2 J. Biol. Chem. 274 1999 5047 5052
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5047-5052
-
-
Hanson, E.S.1
Foot, L.M.2
Leibold, E.A.3
-
6
-
-
0028788316
-
Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2
-
K. Iwai, R.D. Klausner, and T.A. Rouault Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2 EMBO J. 14 1995 5350 5357
-
(1995)
EMBO J.
, vol.14
, pp. 5350-5357
-
-
Iwai, K.1
Klausner, R.D.2
Rouault, T.A.3
-
7
-
-
0032574765
-
Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins
-
K. Iwai, S.K. Drake, N.B. Wehr, A.M. Weissman, T. LaVaute, N. Minato, R.D. Klausner, R.L. Levine, and T.A. Rouault Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins Proc. Natl. Acad. Sci. U. S. A. 95 1998 4924 4928
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 4924-4928
-
-
Iwai, K.1
Drake, S.K.2
Wehr, N.B.3
Weissman, A.M.4
Lavaute, T.5
Minato, N.6
Klausner, R.D.7
Levine, R.L.8
Rouault, T.A.9
-
8
-
-
1642458415
-
Iron-mediated degradation of IRP2: An unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity
-
J. Wang, G. Chen, M. Muckenthaler, B. Galy, M.W. Hentze, and K. Pantopoulos Iron-mediated degradation of IRP2: an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity Mol. Cell. Biol. 24 2004 954 965
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 954-965
-
-
Wang, J.1
Chen, G.2
Muckenthaler, M.3
Galy, B.4
Hentze, M.W.5
Pantopoulos, K.6
-
9
-
-
0141890273
-
Oxygen and iron regulation of iron regulatory protein 2
-
E.S. Hanson, M.L. Rawlins, and E.A. Leibold Oxygen and iron regulation of iron regulatory protein 2 J. Biol. Chem. 278 2003 40337 40342
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40337-40342
-
-
Hanson, E.S.1
Rawlins, M.L.2
Leibold, E.A.3
-
10
-
-
0034663894
-
Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein
-
K. Tanimoto, Y. Makino, T. Pereira, and L. Poellinger Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein EMBO J. 19 2000 4298 4309
-
(2000)
EMBO J.
, vol.19
, pp. 4298-4309
-
-
Tanimoto, K.1
Makino, Y.2
Pereira, T.3
Poellinger, L.4
-
11
-
-
0030963616
-
The hypoxic response: Huffing and HIFing
-
K. Guillemin, and M.A. Krasnow The hypoxic response: huffing and HIFing Cell 89 1997 9 12
-
(1997)
Cell
, vol.89
, pp. 9-12
-
-
Guillemin, K.1
Krasnow, M.A.2
-
13
-
-
0035903468
-
Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
-
N. Masson, C. Willam, P.H. Maxwell, C.W. Pugh, and P.J. Ratcliffe Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation EMBO J. 20 2001 5197 5206
-
(2001)
EMBO J.
, vol.20
, pp. 5197-5206
-
-
Masson, N.1
Willam, C.2
Maxwell, P.H.3
Pugh, C.W.4
Ratcliffe, P.J.5
-
14
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
A.C. Epstein, J.M. Gleadle, L.A. McNeill, K.S. Hewitson, J. O'Rourke, D.R.M. Mukherji, E. Metzen, M.I. Wilson, A. Dhanda, Y.M. Tian, N. Masson, D.L. Hamilton, P. Jaakkola, R. Barstead, J. Hodgkin, P.H. Maxwell, C.W. Pugh, C.J. Schofield, and P.J. Ratcliffe C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation Cell 107 2001 43 54
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mukherji, D.R.M.6
Metzen, E.7
Wilson, M.I.8
Dhanda, A.9
Tian, Y.M.10
Masson, N.11
Hamilton, D.L.12
Jaakkola, P.13
Barstead, R.14
Hodgkin, J.15
Maxwell, P.H.16
Pugh, C.W.17
Schofield, C.J.18
Ratcliffe, P.J.19
-
15
-
-
0035917313
-
2 sensing
-
2 sensing Science 292 2001 464 468
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
16
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation Science 292 2001 468 472
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
17
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
R.K. Bruick, and S.L. McKnight A conserved family of prolyl-4- hydroxylases that modify HIF Science 294 2001 1337 1340
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
18
-
-
0032760945
-
Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes
-
C.J. Schofield, and Z. Zhang Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes Curr. Opin. Struct. Biol. 9 1999 722 731
-
(1999)
Curr. Opin. Struct. Biol.
, vol.9
, pp. 722-731
-
-
Schofield, C.J.1
Zhang, Z.2
-
19
-
-
0033607291
-
Identification of the von Hippel-Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex
-
K. Iwai, K. Yamanaka, T. Kamura, N. Minato, R.C. Conaway, J.W. Conaway, R.D. Klausner, and A. Pause Identification of the von Hippel-Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex Proc. Natl. Acad. Sci. U. S. A. 96 1999 12436 12441
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 12436-12441
-
-
Iwai, K.1
Yamanaka, K.2
Kamura, T.3
Minato, N.4
Conaway, R.C.5
Conaway, J.W.6
Klausner, R.D.7
Pause, A.8
-
20
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
P.H. Maxwell, M.S. Wiesener, G.W. Chang, S.C. Clifford, E.C. Vaux, M.E. Cockman, C.C. Wykoff, C.W. Pugh, E.R. Maher, and P.J. Ratcliffe The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis Nature 399 1999 271 275
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
21
-
-
0002425752
-
Gene expression using the vaccinia virus/T7 RNA polymerase hybrid system
-
J.E. Coligan B.M. Dunn H.L. Ploegh D.W. Speicher P.T. Wingfield John Wiley and Sons
-
O. Elroy-Stein, and B. Moss Gene expression using the vaccinia virus/T7 RNA polymerase hybrid system J.E. Coligan B.M. Dunn H.L. Ploegh D.W. Speicher P.T. Wingfield Current Protocols in Protein Science 1998 John Wiley and Sons 5.15.1 5.15.11
-
(1998)
Current Protocols in Protein Science
, pp. 5151-51511
-
-
Elroy-Stein, O.1
Moss, B.2
-
22
-
-
0028143071
-
Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2
-
F. Samaniego, J. Chin, K. Iwai, T.A. Rouault, and R.D. Klausner Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2 J. Biol. Chem. 269 1994 30904 30910
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30904-30910
-
-
Samaniego, F.1
Chin, J.2
Iwai, K.3
Rouault, T.A.4
Klausner, R.D.5
-
23
-
-
0033776536
-
Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
-
M. Ohh, C.W. Park, M. Ivan, M.A. Hoffman, T.Y. Kim, L.E. Huang, N. Pavletich, V. Chau, and W.G. Kaelin Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein Nat. Cell Biol. 2 2000 423 427
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 423-427
-
-
Ohh, M.1
Park, C.W.2
Ivan, M.3
Hoffman, M.A.4
Kim, T.Y.5
Huang, L.E.6
Pavletich, N.7
Chau, V.8
Kaelin, W.G.9
-
24
-
-
0141989227
-
Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2
-
K. Yamanaka, H. Ishikawa, Y. Megumi, F. Tokunaga, M. Kanie, T.A. Rouault, I. Morishima, N. Minato, K. Ishimori, and K. Iwai Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2 Nat. Cell Biol. 5 2003 336 340
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 336-340
-
-
Yamanaka, K.1
Ishikawa, H.2
Megumi, Y.3
Tokunaga, F.4
Kanie, M.5
Rouault, T.A.6
Morishima, I.7
Minato, N.8
Ishimori, K.9
Iwai, K.10
-
25
-
-
0034682783
-
Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
-
M.E. Cockman, N. Masson, D.R. Mole, P. Jaakkola, G.W. Chang, S.C. Clifford, E.R. Maher, C.W. Pugh, P.J. Ratcliffe, and P.H. Maxwell Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein J. Biol. Chem. 275 2000 25733 25741
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25733-25741
-
-
Cockman, M.E.1
Masson, N.2
Mole, D.R.3
Jaakkola, P.4
Chang, G.W.5
Clifford, S.C.6
Maher, E.R.7
Pugh, C.W.8
Ratcliffe, P.J.9
Maxwell, P.H.10
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