Reduction of Ca2+ stores and capacitative Ca2+ entry is associated with the familial Alzheimer's disease presenilin-2 T122R mutation and anticipates the onset of dementia

Neurobiology of Disease

Volumn 18, Issue 3, 2005, Pages 638-648

  Giacomello, Marta ^a   Barbiero, Laura ^b   Zatti, Giancarlo ^a   Squitti, Rosanna ^b   Binetti, Giuliano ^b   Pozzan, Tullio ^a   Fasolato, Cristina ^a   Ghidoni, Roberta ^b   Pizzo, Paola ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

Author keywords

Alzheimer's disease; Ca2+ homeostasis; Capacitative Ca2+ entry; Fibroblasts; Monozygotic twins; Presenilin

Indexed keywords

CALCIUM ION; PRESENILIN 2; CALCIUM; MEMBRANE PROTEIN; PSEN2 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL STRAIN HEK293; CONTROLLED STUDY; DEMENTIA; EMBRYO; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; MONOZYGOTIC TWINS; NEUROPATHOLOGY; ONSET AGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN FIBROBLAST; AGED; CELL LINE; COMPARATIVE STUDY; DRUG ANTAGONISM; FEMALE; GENETICS; MALE; METABOLISM; MIDDLE AGED; POINT MUTATION;

AGED; ALZHEIMER DISEASE; CALCIUM; CALCIUM SIGNALING; CELL LINE; DEMENTIA; FEMALE; HELA CELLS; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; POINT MUTATION; PRESENILIN-2; TWINS, MONOZYGOTIC;

EID: 14744291484     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2004.10.016     Document Type: Article

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