Carrier-mediated uptake of rhodamine 123: Implications on its use for MDR research

Biochemical and Biophysical Research Communications

Volumn 279, Issue 1, 2000, Pages 124-130

  Cho, Cheong Weon ^a   Liu, Yang ^a   Yan, Xiangdong ^a   Henthorn, Thomas ^a   Ng, Ka Yun ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Cancer; Efflux; Lung carcinoma; MDR; Multidrug resistance; P glycoprotein; Rhodamine 123; Uptake

Indexed keywords

GLYCOPROTEIN P; RHODAMINE 123; VALSPODAR; VERAPAMIL;

ARTICLE; CANCER CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; EFFUSION; HUMAN; HUMAN CELL; INTERNALIZATION; INTRACELLULAR TRANSPORT; LUNG CARCINOMA; MOLECULAR DYNAMICS; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN TRANSPORT;

EID: 0034627219     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3916     Document Type: Article

References (27)

1. Cellular mechanisms of multidrug resistance of tumor cells
2. The biochemistry of P-glycoprotein-mediated multidrug resistance
3. P-glycoprotein and multidrug resistance
4. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
5. The ABC of channel regulation
6. Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines
7. Uptake and retention of adriamycin and daunorubicin by sensitive and anthracycline-resistant sublines of P388 leukemia
8. Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells
9. Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones
10. Functional involvement of P-glycoprotein in blood-brain barrier
11. Localization of mitochondria in living cells with rhodamine 123
12. Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy
13. Cross-resistance to rhodamine 123 in adriamycin- and daunorubicin-resistant Friend leukemia cell variants
14. Use of fluorescent dyes as molecular probes for the study of multidrug resistance
15. Reversal of resistance to rhodamine 123 in adriamycin-resistant Friend leukemia cells
16. Unidirectional fluxes of rhodamine 123 in multidrug-resistant cells: Evidence against direct drug extrusion from the plasma membrane
17. Nonresponsiveness of the metastatic human lung carcinoma MV522 xenograft to conventional anticancer agents
18. Efficacy of MGI 114 (6-hydroxymethylacylfulvene HMAF) against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft
19. Isolation and genetic characterization of human KB cell lines resistant to multiple drugs
20. Active transport of fentanyl by the blood-brain barrier
21. Infuence of dexniguldipine-HC1 on rhodamine-123 accumulation in a multidrug-resistant leukaemia cell line: Comparison with other chemosensitisers
22. Effects of vinblastine, colchicine, and verapamil on rhodamine 123 accumulation in human P-glycoprotein-positive leukemia cells
23. Comparison of staurosporine and four analogues: Their effects on growth, rhodamine 123 retention and binding to P-glycoprotein in multidrug-resistant MCF-7/Adr cells
24. Comparison between anthracyclines and rhodamine-123 accumulation in chronic lymphoid leukemia: Effect of cyclosporin A and verapamil
25. Comparative study of multidrug resistance evaluated by means of the quantitative immunohistochemical detection of P-glycoprotein and the functional release of rhodamine 123
26. Decreased potency of MDR-modulators under serum conditions determined by a functional assay
27. Pharmacologic approaches to reversing multidrug resistance