Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein

Journal of Pharmaceutical Sciences

Volumn 88, Issue 10, 1999, Pages 1067-1072

  Doppenschmitt, Stephan ^a,b   Spahn Langguth, Hildegard ^a   Regardh, Carl Gunnar ^b   Langguth, Peter ^c  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b ASTRAZENECA R AND D   (Sweden)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATENOLOL; DRUG; GLYCOPROTEIN P; METOPROLOL; PAFENOLOL; QUINIDINE; TALINOLOL; VERAPAMIL; VINBLASTINE; VINCRISTINE;

ACTIVE TRANSPORT; ANIMAL CELL; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; DRUG ABSORPTION; DRUG PROTEIN BINDING; DRUG TRANSPORT; GASTROINTESTINAL ABSORPTION; MEMBRANE PERMEABILITY; MICHAELIS MENTEN KINETICS; MONOLAYER CULTURE; NONHUMAN; PASSIVE TRANSPORT; PREDICTION; SIMULATION;

EID: 0032885452     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js980378j     Document Type: Article

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