-
1
-
-
0024329881
-
The biochemistry of P-glycoprotein mediated multidrug resistance
-
Endicott, J. A., and Ling, V. (1989) The biochemistry of P-glycoprotein mediated multidrug resistance. Annu. Rev. Biochem. 58, 137-171
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 137-171
-
-
Endicott, J.A.1
Ling, V.2
-
2
-
-
0027842835
-
Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals
-
Borst, P., Schinkel, A. H., Smit, J. J. M., Wagenaar, E., Van Deemter, L., Smith, A. J., Eijdems, W. H. M., Baas, F., and Zaman, G. J. R. (1993) Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals. Pharmacol. Ther. 60, 289-299
-
(1993)
Pharmacol. Ther.
, vol.60
, pp. 289-299
-
-
Borst, P.1
Schinkel, A.H.2
Smit, J.J.M.3
Wagenaar, E.4
Van Deemter, L.5
Smith, A.J.6
Eijdems, W.H.M.7
Baas, F.8
Zaman, G.J.R.9
-
3
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman, M. M., and Pastan, I. (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62, 385-427
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
4
-
-
0028844806
-
Regulation and function of the multidrug resistance genes in liver
-
(Boyer, J. L., Ockner, R. K., eds) W. B. Saunders, Philadelphia
-
Silverman, J. A., and Thorgeirsson, S. S. (1995) Regulation and function of the multidrug resistance genes in liver. In Progress in Liver Diseases (Boyer, J. L., Ockner, R. K., eds) pp. 101-124, W. B. Saunders, Philadelphia
-
(1995)
Progress in Liver Diseases
, pp. 101-124
-
-
Silverman, J.A.1
Thorgeirsson, S.S.2
-
5
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel, A. H., Smit, J. J. M., van Tellingen, O., Beijnen, J. H., Wagenaar, E., van Deemter, L., Mol, C. A. A. M., van der Valk, M. A., Robanus-Maandag, E. C., te Riele, H. P. J., Berns, and A. J. M., Borst, P. (1994) Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77, 491-502
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.J.10
Berns, A.J.M.11
Borst, P.12
-
6
-
-
0026640274
-
Mdr2 Encodes P-glycoprotein expressed in the bile canalicular membrane as determined by isoform-specific antibodies
-
Buschman, E., Arceci, R. J., Croop, J. M., Che, M., Arias, I. M., Houseman, D. E., and Gros, P. (1992) mdr2 Encodes P-glycoprotein expressed in the bile canalicular membrane as determined by isoform-specific antibodies. J. Biol. Chem. 267, 18093-18099
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 18093-18099
-
-
Buschman, E.1
Arceci, R.J.2
Croop, J.M.3
Che, M.4
Arias, I.M.5
Houseman, D.E.6
Gros, P.7
-
7
-
-
0024544045
-
The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues
-
Croop, J. M., Raymond, M., Haber, D., Devault, A., Arceci, R. J., Gros, P., and Housman, D. E. (1989) The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues. Mol. Cell. Biol. 9, 1345-1350
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 1345-1350
-
-
Croop, J.M.1
Raymond, M.2
Haber, D.3
Devault, A.4
Arceci, R.J.5
Gros, P.6
Housman, D.E.7
-
8
-
-
0027312866
-
Cloning and regulation of the rat mdr2 gene
-
Brown, P. C., Thorgeirsson, S. S., and Silverman, J. A. (1993) Cloning and regulation of the rat mdr2 gene. Nucleic Acids Res. 21, 3885-3891
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3885-3891
-
-
Brown, P.C.1
Thorgeirsson, S.S.2
Silverman, J.A.3
-
9
-
-
0027363563
-
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
-
Smit, J. J. M., Schinkel, A. H., Oude Elferink, R. P. J., Groen, A. K., Wagenaar, E., van Deemter, L., Mol, C. A. A. M., Ottenhoff, R., van der Lugt, N. M. T., van der Valk, M. A., van Roon, M. A., Offerhaus, G. J. A., Berns, A. J. M., and Borst, P. (1993) Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 75, 451-462
-
(1993)
Cell
, vol.75
, pp. 451-462
-
-
Smit, J.J.M.1
Schinkel, A.H.2
Oude Elferink, R.P.J.3
Groen, A.K.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Ottenhoff, R.8
Van Der Lugt, N.M.T.9
Van Der Valk, M.A.10
Van Roon, M.A.11
Offerhaus, G.J.A.12
Berns, A.J.M.13
Borst, P.14
-
10
-
-
0028028436
-
Mice with homozygous disruption of the mdr2 P-glycoprotein gene: A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis
-
Mauad, T. H., van Nieuwkerk, C. M. J., Dingemans, K. P., Smit, J. J. M., Schinkel, A. H., Notenboom, R. G. E., van den Bergh Weerman, M. A., Verkruisen, R. P., Groen, A. K., Oude Elferink, R. P. J., Borst, P., and Offerhaus, G. J. A. (1994) Mice with homozygous disruption of the mdr2 P-glycoprotein gene: A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis. Am. J. Pathol. 145, 1237-1245
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1237-1245
-
-
Mauad, T.H.1
Van Nieuwkerk, C.M.J.2
Dingemans, K.P.3
Smit, J.J.M.4
Schinkel, A.H.5
Notenboom, R.G.E.6
Van Den Bergh Weerman, M.A.7
Verkruisen, R.P.8
Groen, A.K.9
Oude Elferink, R.P.J.10
Borst, P.11
Offerhaus, G.J.A.12
-
11
-
-
0028307550
-
Phosphotidylcholine translocase: A physiological role for the mdr2 gene
-
Ruetz, S., and Gros, P. (1994) Phosphotidylcholine translocase: A physiological role for the mdr2 gene. Cell 77, 1071-1081
-
(1994)
Cell
, vol.77
, pp. 1071-1081
-
-
Ruetz, S.1
Gros, P.2
-
12
-
-
1842298460
-
Structure and function of P-glycoprotein in the normal liver and intestine
-
(Ernster, L., ed) Japan Sci. Soc. Press, Tokyo
-
Arias, I. M., Gatmaitan, Z., Mazzanti, R., Shu, H., and Kumamoto, Y. (1991) Structure and function of P-glycoprotein in the normal liver and intestine. In Xenobiotics and Canter (Ernster, L., ed) pp. 229-239, Japan Sci. Soc. Press, Tokyo
-
(1991)
Xenobiotics and Canter
, pp. 229-239
-
-
Arias, I.M.1
Gatmaitan, Z.2
Mazzanti, R.3
Shu, H.4
Kumamoto, Y.5
-
13
-
-
0024548599
-
Expression of a multidrug resistance gene in human cancers
-
Goldstein, L. J., Galski, H., Fojo, A. T., Willingham, M., Lai, S.-L., Gazdar, A., Pirker, R., Green, A., Crist, W., Brodeur, G. M., Lieber, M., Cossman, J., Gottesman, M. M., and Pastan, I. (1989) Expression of a multidrug resistance gene in human cancers. J. Natl. Cancer Inst. 81, 116-124
-
(1989)
J. Natl. Cancer Inst.
, vol.81
, pp. 116-124
-
-
Goldstein, L.J.1
Galski, H.2
Fojo, A.T.3
Willingham, M.4
Lai, S.-L.5
Gazdar, A.6
Pirker, R.7
Green, A.8
Crist, W.9
Brodeur, G.M.10
Lieber, M.11
Cossman, J.12
Gottesman, M.M.13
Pastan, I.14
-
14
-
-
0027171458
-
MDR1 (multidrug resistance) gene expression in human primary liver cancer and cirrhosis
-
Chenivesse, X., Franco, D., and Bréchot, C. (1993) MDR1 (multidrug resistance) gene expression in human primary liver cancer and cirrhosis. J. Hepatol. 18, 168:172
-
(1993)
J. Hepatol.
, vol.18
, pp. 168
-
-
Chenivesse, X.1
Franco, D.2
Bréchot, C.3
-
15
-
-
0028069259
-
Immunohistochemical study of expression and the cellular localization of the multidrug resistance gene product P-glycoprotein in primary liver carcinoma
-
Itsubo, M., Ishikawa, T., Toda, G., and Tanaka, M. (1993) Immunohistochemical study of expression and the cellular localization of the multidrug resistance gene product P-glycoprotein in primary liver carcinoma. Cancer 73, 298-303
-
(1993)
Cancer
, vol.73
, pp. 298-303
-
-
Itsubo, M.1
Ishikawa, T.2
Toda, G.3
Tanaka, M.4
-
16
-
-
0026071402
-
Human hepatocellular carcinoma cell lines exhibit multidrug resistance unrelated to MDR1 gene expression
-
Shen, D.-W., Lu, Y.-G., Chin, K.-V., Pastan, I., and Gottesman, M. M. (1991) Human hepatocellular carcinoma cell lines exhibit multidrug resistance unrelated to MDR1 gene expression. J. Cell Sci. 98, 317-322
-
(1991)
J. Cell Sci.
, vol.98
, pp. 317-322
-
-
Shen, D.-W.1
Lu, Y.-G.2
Chin, K.-V.3
Pastan, I.4
Gottesman, M.M.5
-
17
-
-
0028334832
-
MDR1 gene expression: Its effect on drug resistance to doxorubicin in human hepatocellular carcinoma cell lines
-
Park, J.-G., Lee, S.-K., Hong, I.-G., Kim, H.-S., Lim, K.-H., Choe, K.-J., Kim, W.-H., Kim, Y.-I., Tsuruo, T., and Gottesman, M. M. (1994) MDR1 gene expression: Its effect on drug resistance to doxorubicin in human hepatocellular carcinoma cell lines. J. Natl. Cancer Inst. 86, 700-705
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 700-705
-
-
Park, J.-G.1
Lee, S.-K.2
Hong, I.-G.3
Kim, H.-S.4
Lim, K.-H.5
Choe, K.-J.6
Kim, W.-H.7
Kim, Y.-I.8
Tsuruo, T.9
Gottesman, M.M.10
-
18
-
-
0023689651
-
Conduction of MDR-1 multidrug resistance and cytochrome P-450 genes in rat liver by xenobiotics
-
Burt, R. K., and Thorgeirsson, S. S. (1988) Conduction of MDR-1 multidrug resistance and cytochrome P-450 genes in rat liver by xenobiotics. J. Natl. Cancer Inst. 80, 1381-1386
-
(1988)
J. Natl. Cancer Inst.
, vol.80
, pp. 1381-1386
-
-
Burt, R.K.1
Thorgeirsson, S.S.2
-
19
-
-
0029915184
-
Regulation of mdr1b gene expression in Fischer, Wistar and Sprague-Dawley rats in vivo and in vitro
-
Hill, B. A., Brown, P. C., Preisegger, K.-H., Silverman, J. A. (1996) Regulation of mdr1b gene expression in Fischer, Wistar and Sprague-Dawley rats in vivo and in vitro. Carcinogenesis 17, 451-457
-
(1996)
Carcinogenesis
, vol.17
, pp. 451-457
-
-
Hill, B.A.1
Brown, P.C.2
Preisegger, K.-H.3
Silverman, J.A.4
-
20
-
-
0026327875
-
Regulation of 2-acetylaminofluorene and 3-methylcholanthrene mediated induction of mdr and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver
-
Gant, T. W., Silverman, J. A., Bisgaard, H. C., Burt, R. K., Marino, P. A., and Thorgeirsson, S. S. (1991) Regulation of 2-acetylaminofluorene and 3-methylcholanthrene mediated induction of mdr and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver. Mol. Carcingen. 4, 499-509
-
(1991)
Mol. Carcingen.
, vol.4
, pp. 499-509
-
-
Gant, T.W.1
Silverman, J.A.2
Bisgaard, H.C.3
Burt, R.K.4
Marino, P.A.5
Thorgeirsson, S.S.6
-
21
-
-
0028004345
-
Metabolic activation of 2-acetylaminofluorene is required for induction of multidrug resistance gene expression in rat liver cells
-
Schrenk, D., Gant, T. W., Michalke, A., Orzechowski, A., Silverman, J. A., Battula, N., and Thorgeirsson, S. S. (1994) Metabolic activation of 2-acetylaminofluorene is required for induction of multidrug resistance gene expression in rat liver cells. Carcinogenesis 15, 2541-2546
-
(1994)
Carcinogenesis
, vol.15
, pp. 2541-2546
-
-
Schrenk, D.1
Gant, T.W.2
Michalke, A.3
Orzechowski, A.4
Silverman, J.A.5
Battula, N.6
Thorgeirsson, S.S.7
-
22
-
-
0028958395
-
Phenotypic variability in induction of P-glycoprotein mRNA by aromatic hydrocarbons in primary human hepatocytes
-
Schuetz, E. G., Schuetz, J. D., Thompson, M. T., Fisher, R. A., Madariage, J. R., and Strom, S. C. (1995) Phenotypic variability in induction of P-glycoprotein mRNA by aromatic hydrocarbons in primary human hepatocytes. Mol. Carcinog. 12, 61-65
-
(1995)
Mol. Carcinog.
, vol.12
, pp. 61-65
-
-
Schuetz, E.G.1
Schuetz, J.D.2
Thompson, M.T.3
Fisher, R.A.4
Madariage, J.R.5
Strom, S.C.6
-
23
-
-
0029028792
-
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
-
Wacher, V. J., Wu, C.-Y., and Benet, L. Z. (1995) Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy. Mol. Carcinog. 13, 129-134
-
(1995)
Mol. Carcinog.
, vol.13
, pp. 129-134
-
-
Wacher, V.J.1
Wu, C.-Y.2
Benet, L.Z.3
-
24
-
-
0030059953
-
Modulators and substrates of P-glycoprotein and cytochrome p4503A coordinately up-regulate these proteins in human colon carcinoma cells
-
Schuetz, E. G., Beck, W. T., and Schuetz, J. D. (1996) Modulators and substrates of P-glycoprotein and cytochrome p4503A coordinately up-regulate these proteins in human colon carcinoma cells. Mol. Pharmacol. 49, 311-318
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 311-318
-
-
Schuetz, E.G.1
Beck, W.T.2
Schuetz, J.D.3
-
25
-
-
0028889421
-
Divergent regulation of the class II P-glycoprotein gene in primary cultures of hepatocytes versus H35 hepatoma by glucocorticoids
-
Schuetz, J. D., Silvennan, J. A., Thottassery, J. V., Furuya, K. N., and Schuetz, E. G. (1995) Divergent regulation of the class II P-glycoprotein gene in primary cultures of hepatocytes versus H35 hepatoma by glucocorticoids. Cell Growth & Differ. 6, 1321-1332
-
(1995)
Cell Growth & Differ.
, vol.6
, pp. 1321-1332
-
-
Schuetz, J.D.1
Silvennan, J.A.2
Thottassery, J.V.3
Furuya, K.N.4
Schuetz, E.G.5
-
26
-
-
0027296765
-
Regulation by dexamethasone of P-glycoprotein expression in cultured rat hepatocytes
-
Fardel, O., Lecureur, V., and Guillouzo, A. (1993) Regulation by dexamethasone of P-glycoprotein expression in cultured rat hepatocytes. FEBS Lett. 327, 189-193
-
(1993)
FEBS Lett.
, vol.327
, pp. 189-193
-
-
Fardel, O.1
Lecureur, V.2
Guillouzo, A.3
-
27
-
-
0026332697
-
Dexamethasone prevents the growth inhibitory effects of recombinant tumor necrosis factor in a rat hepatomea cell line Reuber-RC-3: An association with the changes in the messenger RNA levels for multidrug resistance gene
-
Chapekar, M. S., Hugget, A. C., and Cheng, C. (1991) Dexamethasone prevents the growth inhibitory effects of recombinant tumor necrosis factor in a rat hepatomea cell line Reuber-RC-3: An association with the changes in the messenger RNA levels for multidrug resistance gene. Biochem. Biophys. Res. Commun. 181, 1524-1531
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.181
, pp. 1524-1531
-
-
Chapekar, M.S.1
Hugget, A.C.2
Cheng, C.3
-
28
-
-
0028817783
-
Modulation of P-glycoprotein and mdr1b expression by growth factors in primary rat hepatocyte culture
-
Hirsch-Ernst, K. I., Ziemann, C., Schmitz-Salue, C., Foth, H., and Kahl, G. F. (1995) Modulation of P-glycoprotein and mdr1b expression by growth factors in primary rat hepatocyte culture. Biochem. Biophys. Res. Commun. 215, 179-185
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.215
, pp. 179-185
-
-
Hirsch-Ernst, K.I.1
Ziemann, C.2
Schmitz-Salue, C.3
Foth, H.4
Kahl, G.F.5
-
29
-
-
0027300475
-
P-glycoprotein expression in human, mouse, hamster and rat hepatocytes in primary culture
-
Fardel, O., Morel, F., and Guillouzo, A. (1993) P-glycoprotein expression in human, mouse, hamster and rat hepatocytes in primary culture. Carcinogenesis 14, 781-783
-
(1993)
Carcinogenesis
, vol.14
, pp. 781-783
-
-
Fardel, O.1
Morel, F.2
Guillouzo, A.3
-
30
-
-
0026764538
-
Regulation of P-glycoprotein gene expression in hepatocytes and liver cell lines by a trans-acting transcriptional repressor
-
Gant, T. W., Silverman, J. A., and Thorgeirsson, S. S. (1992) Regulation of P-glycoprotein gene expression in hepatocytes and liver cell lines by a trans-acting transcriptional repressor. Nucleic Acids Res. 20, 2841-2846
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 2841-2846
-
-
Gant, T.W.1
Silverman, J.A.2
Thorgeirsson, S.S.3
-
31
-
-
0028787391
-
Induction of P-glycoprotein by protein synthesis inhibition is not controlled by a transcriptional repressor protein in rat and human liver cells
-
Schuetz, J. D., Strom, S. C., and Schuetz, E. G. (1995) Induction of P-glycoprotein by protein synthesis inhibition is not controlled by a transcriptional repressor protein in rat and human liver cells. J. Cell. Physiol. 165, 261-272
-
(1995)
J. Cell. Physiol.
, vol.165
, pp. 261-272
-
-
Schuetz, J.D.1
Strom, S.C.2
Schuetz, E.G.3
-
32
-
-
0023179571
-
Expression of the multidrug-resistance gene in hepatocarcinogenesis and regenerating rat liver
-
Thorgeirsson, S. S., Huber, B. E., Sorrell, S., Fojo, A. T., Pastan, I., and Gottesman, M. M. (1987) Expression of the multidrug-resistance gene in hepatocarcinogenesis and regenerating rat liver. Science 236, 1120-1122
-
(1987)
Science
, vol.236
, pp. 1120-1122
-
-
Thorgeirsson, S.S.1
Huber, B.E.2
Sorrell, S.3
Fojo, A.T.4
Pastan, I.5
Gottesman, M.M.6
-
33
-
-
0027445209
-
Expression of multidrug resistance genes in rat liver during regeneration and after carbon tetrachloride intoxication
-
Nakatsukasa, H., Silverman, J. A., Gant, T. W., Evarts, R. P., and Thorgeirsson, S. S. (1993) Expression of multidrug resistance genes in rat liver during regeneration and after carbon tetrachloride intoxication. Hepatology 18, 1202-1207
-
(1993)
Hepatology
, vol.18
, pp. 1202-1207
-
-
Nakatsukasa, H.1
Silverman, J.A.2
Gant, T.W.3
Evarts, R.P.4
Thorgeirsson, S.S.5
-
34
-
-
0025386379
-
Regulation of the multidrug resistance gene in regenerating rat liver
-
Marino, P. A., Gottesman, M. M., and Pastan, I. (1989) Regulation of the multidrug resistance gene in regenerating rat liver. Cell Growth & Differ. 1, 57-62
-
(1989)
Cell Growth & Differ.
, vol.1
, pp. 57-62
-
-
Marino, P.A.1
Gottesman, M.M.2
Pastan, I.3
-
35
-
-
0027299120
-
Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates
-
Schrenk, D., Gant, T. W., Preisegger, K.-H., Silverman, J. A., Marino, P., and Thorgeirsson, S. S. (1993) Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates. Hepatology 17, 854-860
-
(1993)
Hepatology
, vol.17
, pp. 854-860
-
-
Schrenk, D.1
Gant, T.W.2
Preisegger, K.-H.3
Silverman, J.A.4
Marino, P.5
Thorgeirsson, S.S.6
-
36
-
-
0027441097
-
17β-Estradiol glucuronide: An inducer of cholestasis and a physiological substrate for the multidrug resistance transporter
-
Gosland, M., Tsuboi, C., Hoffman, T., Goodin, S., and Vore, M. (1993) 17β-Estradiol glucuronide: An inducer of cholestasis and a physiological substrate for the multidrug resistance transporter. Cancer Res. 53, 5382-5385
-
(1993)
Cancer Res.
, vol.53
, pp. 5382-5385
-
-
Gosland, M.1
Tsuboi, C.2
Hoffman, T.3
Goodin, S.4
Vore, M.5
-
37
-
-
0013659750
-
Carcinogen-induced mdr overexpression is associated with xenobiotic resistance in rat preneoplastic liver nodules and hepatocellular carcinomas
-
Fairchild, C. R., Ivy, S. P., Rushmore, T., Lee, G., Koo, P., Goldsmith, M. E., Myers, C., Farber, E., and Cowan, K. H. (1987) Carcinogen-induced mdr overexpression is associated with xenobiotic resistance in rat preneoplastic liver nodules and hepatocellular carcinomas. Proc. Natl. Acad. Sci. USA 84, 7701-7705
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7701-7705
-
-
Fairchild, C.R.1
Ivy, S.P.2
Rushmore, T.3
Lee, G.4
Koo, P.5
Goldsmith, M.E.6
Myers, C.7
Farber, E.8
Cowan, K.H.9
-
38
-
-
0026471004
-
Cellular pattern of multidrug-resistance gene expression during chemical hepatocarcinogenesis in the rat
-
Nakatsukasa, H., Evarts, R. P., Burt, R. K., and Nagy, P., Thorgeirsson, S. S. (1992) Cellular pattern of multidrug-resistance gene expression during chemical hepatocarcinogenesis in the rat. Mol. Carcinog. 6, 190-198
-
(1992)
Mol. Carcinog.
, vol.6
, pp. 190-198
-
-
Nakatsukasa, H.1
Evarts, R.P.2
Burt, R.K.3
Nagy, P.4
Thorgeirsson, S.S.5
-
39
-
-
0026687242
-
P-Glycoprotein expression during tumor progression in the rat liver
-
Bradley, G., Sharma, R., Rajalakshmi, S., and Ling, V. (1992) P-Glycoprotein expression during tumor progression in the rat liver. Cancer Res. 52, 5154-5161
-
(1992)
Cancer Res.
, vol.52
, pp. 5154-5161
-
-
Bradley, G.1
Sharma, R.2
Rajalakshmi, S.3
Ling, V.4
-
40
-
-
0025186615
-
Overexpression of P-glycoprotein in rat hepatocellular carcinomas
-
Volm, M., Zerban, H., Mattern, J., and Efferth, T. (1990) Overexpression of P-glycoprotein in rat hepatocellular carcinomas. Carcinogesis 11, 169-172
-
(1990)
Carcinogesis
, vol.11
, pp. 169-172
-
-
Volm, M.1
Zerban, H.2
Mattern, J.3
Efferth, T.4
-
41
-
-
0027377964
-
Activation of distinct multidrug-resistance (P-glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis
-
Teeter, L. D., Estes, M., Chan, J. Y., Atassi, H., Sell, S., Becker, F. F., and Kuo, M. T. (1993) Activation of distinct multidrug-resistance (P-glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis. Mol. Carcinog. 8, 67-73
-
(1993)
Mol. Carcinog.
, vol.8
, pp. 67-73
-
-
Teeter, L.D.1
Estes, M.2
Chan, J.Y.3
Atassi, H.4
Sell, S.5
Becker, F.F.6
Kuo, M.T.7
-
42
-
-
0026784423
-
Multidrug resistance in Yoshida rat ascites hepatoma cell lines
-
Miyamoto, K.-I., Wakusawa, S., Nakamura, S., Tajima, K., and Hidaka, H. (1992) Multidrug resistance in Yoshida rat ascites hepatoma cell lines. Anticancer Res. 12, 649-654
-
(1992)
Anticancer Res.
, vol.12
, pp. 649-654
-
-
Miyamoto, K.-I.1
Wakusawa, S.2
Nakamura, S.3
Tajima, K.4
Hidaka, H.5
-
43
-
-
0028722653
-
Transcriptional regulation of multidrug resistance gene expression
-
(Goldstein, L. J., Ozols, R. F., eds) Kluwer Academic, Norwell
-
Thorgeirsson, S. S., Gant, T. W., and Silverman, J. A. (1994) Transcriptional regulation of multidrug resistance gene expression. In Anticancer Drug Resistance (Goldstein, L. J., Ozols, R. F., eds) pp. 57-68. Kluwer Academic, Norwell
-
(1994)
Anticancer Drug Resistance
, pp. 57-68
-
-
Thorgeirsson, S.S.1
Gant, T.W.2
Silverman, J.A.3
-
44
-
-
0026213268
-
Analysis of the Chinese hamster P-glycoprotein/multidrug resistance gene pgp1 reveals that the AP-1 site is essential for full promoter activity
-
Teeter, L. D., Eckersburg, T., Tsai, Y., and Kuo, M. T. (1991) Analysis of the Chinese hamster P-glycoprotein/multidrug resistance gene pgp1 reveals that the AP-1 site is essential for full promoter activity. Cell Growth & Differ. 2, 429-437
-
(1991)
Cell Growth & Differ.
, vol.2
, pp. 429-437
-
-
Teeter, L.D.1
Eckersburg, T.2
Tsai, Y.3
Kuo, M.T.4
-
45
-
-
0025993362
-
Structural and functional analyses of the promoter of the murine multidrug resistance gene mdr3/mdr1a reveal a negative element containing the AP-1 binding site
-
Ikeguchi, M., Teeter, L. D., Eckersberg, T., Ganapathi, R., and Kuo, M. T. (1991) Structural and functional analyses of the promoter of the murine multidrug resistance gene mdr3/mdr1a reveal a negative element containing the AP-1 binding site. DNA Cell Biol. 10, 639-649
-
(1991)
DNA Cell Biol.
, vol.10
, pp. 639-649
-
-
Ikeguchi, M.1
Teeter, L.D.2
Eckersberg, T.3
Ganapathi, R.4
Kuo, M.T.5
-
46
-
-
0025879636
-
Structural and functional analysis of the mouse mdr1b gene promoter
-
Cohen, D., Piekarz, R., Hsu, S. I.-H., DePinho, R. A., Carrasco, N., and Horwitz, S. B. (1991) Structural and functional analysis of the mouse mdr1b gene promoter. J. Biol. Chem. 254, 2239-2244
-
(1991)
J. Biol. Chem.
, vol.254
, pp. 2239-2244
-
-
Cohen, D.1
Piekarz, R.2
Hsu, S.I.-H.3
DePinho, R.A.4
Carrasco, N.5
Horwitz, S.B.6
-
47
-
-
0029035652
-
Characterization of the basal and carcinogen regulatory elements of the rat mdr1b promoter
-
Silverman, J. A., and Hill, B. A. (1995) Characterization of the basal and carcinogen regulatory elements of the rat mdr1b promoter. Mol. Carcinog. 13, 50-59
-
(1995)
Mol. Carcinog.
, vol.13
, pp. 50-59
-
-
Silverman, J.A.1
Hill, B.A.2
-
48
-
-
0027467508
-
A Y-box consensus sequence is required for basal expression of the human multidrug resistance (mdr1) gene
-
Goldsmith, M. E., Madden, M. J., Morrow, C. S., and Cowan, K. H. (1993) A Y-box consensus sequence is required for basal expression of the human multidrug resistance (mdr1) gene. J. Biol. Chem. 268, 5856-5860
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5856-5860
-
-
Goldsmith, M.E.1
Madden, M.J.2
Morrow, C.S.3
Cowan, K.H.4
-
49
-
-
0028826138
-
Coordination of transcription factors, NF-Y and C/EBPβ, in the regulation of the mdr1b promoter
-
Yu, L., Wu, Q., Yang, C.-P. H., and Horwitz, S. B. (1995) Coordination of transcription factors, NF-Y and C/EBPβ, in the regulation of the mdr1b promoter. Cell Growth & Differ. 6, 1505-1512
-
(1995)
Cell Growth & Differ.
, vol.6
, pp. 1505-1512
-
-
Yu, L.1
Wu, Q.2
Yang, C.-P.H.3
Horwitz, S.B.4
-
50
-
-
0028149768
-
NF-IL6, a member of the C/EBP family of transcription factors, binds and trans-activates the human MDR1 gene promoter
-
Combates, N. J., Rzepka, R. W., Chen, Y.-N. P., and Cohen, D. (1994) NF-IL6, a member of the C/EBP family of transcription factors, binds and trans-activates the human MDR1 gene promoter. J. Biol. Chem. 269, 29715-29719
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 29715-29719
-
-
Combates, N.J.1
Rzepka, R.W.2
Chen, Y.-N.P.3
Cohen, D.4
-
51
-
-
0024820183
-
The direct activation of human multidrug resistance gene by anticancer agents
-
Kohno, K., Sato, S., Takano, H., Matsuo, K., and Kuwano, M. (1989) The direct activation of human multidrug resistance gene by anticancer agents. Biochem. Biophys. Res. Commun. 164, 1415-1421
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.164
, pp. 1415-1421
-
-
Kohno, K.1
Sato, S.2
Takano, H.3
Matsuo, K.4
Kuwano, M.5
-
52
-
-
0025060257
-
Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells
-
Chin, K.-V., Tanaka, S., Darlington, G., Pastan, I., and Gottesman, M. M. (1990) Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells. J. Biol. Chem. 265, 221-226
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 221-226
-
-
Chin, K.-V.1
Tanaka, S.2
Darlington, G.3
Pastan, I.4
Gottesman, M.M.5
-
53
-
-
0028283519
-
Reversible transcription activation of mdr1 by sodium butyrate treatment of human colon cancer cells
-
Morrow, C. S., Nakagawa, M., Goldsmith, M. E., Madden, M. J., and Cowan, K. H. (1994) Reversible transcription activation of mdr1 by sodium butyrate treatment of human colon cancer cells. J. Biol. Chem. 269, 10739-10746
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10739-10746
-
-
Morrow, C.S.1
Nakagawa, M.2
Goldsmith, M.E.3
Madden, M.J.4
Cowan, K.H.5
-
54
-
-
0028820126
-
12-O-Tetradecanoylphorbol-13-acetate activation of the MDR1 promoter is mediated by EGR1
-
McCoy, C., Smith, D. E., and Cornwell, M. M. (1995) 12-O-Tetradecanoylphorbol-13-acetate activation of the MDR1 promoter is mediated by EGR1. Mol. Cell. Biol. 15, 6100-6108
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6100-6108
-
-
McCoy, C.1
Smith, D.E.2
Cornwell, M.M.3
-
55
-
-
0028969859
-
Characterization of the promoter region of the human MDR3 P-glycoprotein gene
-
Smit, J. J. M., van Deemter, L., Wagenaar, E., Schinkel, A. H., and Borst, P. (1995) Characterization of the promoter region of the human MDR3 P-glycoprotein gene. Biochim. Biophys. Acta 1261, 44-56
-
(1995)
Biochim. Biophys. Acta
, vol.1261
, pp. 44-56
-
-
Smit, J.J.M.1
Van Deemter, L.2
Wagenaar, E.3
Schinkel, A.H.4
Borst, P.5
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