Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides

Nucleic Acids Research

Volumn 33, Issue 1, 2005, Pages 27-42

  Turner, John J ^a   Arzumanov, Andrey A ^a   Gait, Michael J ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ARGININE; CATION; FLUORESCEIN; LIPID; LOCKED NUCLEIC ACID; LYSINE; METHYL GROUP; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; OLIGONUCLEOTIDE; PENETRATIN; THIOL DERIVATIVE; TRANSACTIVATOR PROTEIN; VIRUS RNA; ANTISENSE OLIGONUCLEOTIDE; DISULFIDE; NUCLEOTIDE; PEPTIDE NUCLEIC ACID;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; AMINO TERMINAL SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; CELL ASSAY; CELL COMPARTMENTALIZATION; CELL NUCLEUS; CONJUGATION; CONTROLLED STUDY; CYTOSOL; DISULFIDE BOND; DNA RESPONSIVE ELEMENT; DRUG SYNTHESIS; DRUG UPTAKE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRACELLULAR TRANSPORT; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN PURIFICATION; TRANSACTIVATION; CELL CULTURE; CELL MEMBRANE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HELA CELL; HYDROPHOBICITY; LONG TERMINAL REPEAT; METABOLISM; SYNTHESIS; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; CELL MEMBRANE; CELLS, CULTURED; DISULFIDES; FIBROBLASTS; GENE PRODUCTS, TAT; HELA CELLS; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; HYDROPHOBICITY; OLIGONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; PEPTIDE NUCLEIC ACIDS; THIONUCLEOTIDES; TRANS-ACTIVATION (GENETICS);

EID: 13744259834     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gki142     Document Type: Article

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