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Volumn 15, Issue 2, 2004, Pages 290-299

Cellular Uptake of Antisense Morpholino Oligomers Conjugated to Arginine-Rich Peptides

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CELL CULTURE; GENES; PEPTIDES; RNA;

EID: 1642321105     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc034221g     Document Type: Article
Times cited : (184)

References (42)
  • 1
    • 0030862707 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: Design, preparation, and properties
    • Summerton, J., and Weller, D. (1997) Morpholino antisense oligomers: design, preparation, and properties. Antisense Nucleic Acid Drug Dev. 7, 187-195.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 187-195
    • Summerton, J.1    Weller, D.2
  • 2
    • 0032699477 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: The case for an RNase H-independent structural type
    • Summerton, J. (1999) Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochim. Biophys. Acta 1489, 141-158.
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 141-158
    • Summerton, J.1
  • 3
    • 0030015872 scopus 로고    scopus 로고
    • In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis factor-alpha mRNA
    • Taylor, M. F., Paulauskis, J. D., Weller, D. D., and Kobzik, L. (1996) In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis factor-alpha mRNA. J. Biol. Chem. 271, 17445-17452.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17445-17452
    • Taylor, M.F.1    Paulauskis, J.D.2    Weller, D.D.3    Kobzik, L.4
  • 4
    • 0031239634 scopus 로고    scopus 로고
    • Comparison of efficacy of antisense oligomers directed toward TNF-alpha in helper T and macrophage cell lines
    • Taylor, M. F., Paulauskis, J. D., Weller, D. D., and Kobzik, L. (1997) Comparison of efficacy of antisense oligomers directed toward TNF-alpha in helper T and macrophage cell lines. Cytokine 9, 672-681.
    • (1997) Cytokine , vol.9 , pp. 672-681
    • Taylor, M.F.1    Paulauskis, J.D.2    Weller, D.D.3    Kobzik, L.4
  • 5
    • 0031828692 scopus 로고    scopus 로고
    • Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages
    • Taylor, M. F., Weller, D. D., and Kobzik, L. (1998) Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages. Antisense Nucleic Acid Drug Dev. 8, 199-205.
    • (1998) Antisense Nucleic Acid Drug Dev. , vol.8 , pp. 199-205
    • Taylor, M.F.1    Weller, D.D.2    Kobzik, L.3
  • 7
    • 0033916111 scopus 로고    scopus 로고
    • Antiproliferative effects of steric blocking phosphorodiamidate morpholino antisense agents directed against c-myc
    • Hudziak, R. M., Summerton, J., Weller, D. D., and Iversen, P. L. (2000) Antiproliferative effects of steric blocking phosphorodiamidate morpholino antisense agents directed against c-myc. Antisense Nucleic Acid Drug Dev. 10, 163-176.
    • (2000) Antisense Nucleic Acid Drug Dev. , vol.10 , pp. 163-176
    • Hudziak, R.M.1    Summerton, J.2    Weller, D.D.3    Iversen, P.L.4
  • 8
    • 0035181386 scopus 로고    scopus 로고
    • Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers
    • Stein, D. A., Skilling, D. E., Iversen, P. L., and Smith, A. W. (2001) Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers. Antisense Nucleic Acid Drug Dev. 11, 317-325.
    • (2001) Antisense Nucleic Acid Drug Dev. , vol.11 , pp. 317-325
    • Stein, D.A.1    Skilling, D.E.2    Iversen, P.L.3    Smith, A.W.4
  • 9
    • 33749208496 scopus 로고    scopus 로고
    • Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant
    • Nasevicius, A., Larson, J., and Ekker, S. C. (2000) Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast 17, 294-301.
    • (2000) Yeast , vol.17 , pp. 294-301
    • Nasevicius, A.1    Larson, J.2    Ekker, S.C.3
  • 10
    • 0034213262 scopus 로고    scopus 로고
    • Beta-catenin signaling activity dissected in the early Xenopus embryo: A novel antisense approach
    • Heasman, J., Kofron, M., and Wylie, C. (2000) Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach. Dev. Biol. 222, 124-134.
    • (2000) Dev. Biol. , vol.222 , pp. 124-134
    • Heasman, J.1    Kofron, M.2    Wylie, C.3
  • 11
    • 0035122848 scopus 로고    scopus 로고
    • SpKrl: A direct target of beta-catenin regulation required for endoderm differentiation in sea urchin embryos
    • Howard, E. W., Newman, L. A., Oleksyn, D. W., Angerer, R. C., and Angerer, L. M. (2001) SpKrl: a direct target of beta-catenin regulation required for endoderm differentiation in sea urchin embryos. Development 128, 365-375.
    • (2001) Development , vol.128 , pp. 365-375
    • Howard, E.W.1    Newman, L.A.2    Oleksyn, D.W.3    Angerer, R.C.4    Angerer, L.M.5
  • 12
    • 0035042293 scopus 로고    scopus 로고
    • The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos
    • Kos, R., Reedy, M. V., Johnson, R. L., and Erickson, C. A. (2001) The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. Development 128, 1467-1479.
    • (2001) Development , vol.128 , pp. 1467-1479
    • Kos, R.1    Reedy, M.V.2    Johnson, R.L.3    Erickson, C.A.4
  • 14
    • 0033811705 scopus 로고    scopus 로고
    • Intracellular delivery strategies for antisense phosphorodiamidate morpholino oligomers
    • Ghosh, C., and Iversen, P. L. (2000) Intracellular delivery strategies for antisense phosphorodiamidate morpholino oligomers. Antisense Nucleic Acid Drug Dev. 10, 263-274.
    • (2000) Antisense Nucleic Acid Drug Dev. , vol.10 , pp. 263-274
    • Ghosh, C.1    Iversen, P.L.2
  • 15
    • 0034910904 scopus 로고    scopus 로고
    • Achieving efficient delivery of morpholino oligos in cultured cells
    • Morcos, P. A. (2001) Achieving efficient delivery of morpholino oligos in cultured cells. Genesis 30, 94-102.
    • (2001) Genesis , vol.30 , pp. 94-102
    • Morcos, P.A.1
  • 17
    • 0028239908 scopus 로고
    • The third helix of the Antennapedia homeodomain translocates through biological membranes
    • Derossi, D., Joliot, A. H., Chassaing, G., and Prochiantz, A. (1994) The third helix of the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem. 269, 10444-10450.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10444-10450
    • Derossi, D.1    Joliot, A.H.2    Chassaing, G.3    Prochiantz, A.4
  • 18
    • 0030904245 scopus 로고    scopus 로고
    • A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
    • Vives, E., Brodin, P., and Lebleu, B. (1997) A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272, 16010-16017.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16010-16017
    • Vives, E.1    Brodin, P.2    Lebleu, B.3
  • 22
    • 0034640463 scopus 로고    scopus 로고
    • Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells
    • Villa, R., Folini, M., Lualdi, S., Veronese, S., Daidone, M. G., and Zaffaroni, N. (2000) Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells. FEBS Lett. 473, 241-248.
    • (2000) FEBS Lett. , vol.473 , pp. 241-248
    • Villa, R.1    Folini, M.2    Lualdi, S.3    Veronese, S.4    Daidone, M.G.5    Zaffaroni, N.6
  • 23
    • 0035863391 scopus 로고    scopus 로고
    • Synthetic protein transduction domains: Enhanced transduction potential in vitro and in vivo
    • Ho, A., Schwarze, S. R., Mermelstein, S. J., Waksman, G., and Dowdy, S. F. (2001) Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo. Cancer Res. 61, 474-477.
    • (2001) Cancer Res. , vol.61 , pp. 474-477
    • Ho, A.1    Schwarze, S.R.2    Mermelstein, S.J.3    Waksman, G.4    Dowdy, S.F.5
  • 25
    • 0034700141 scopus 로고    scopus 로고
    • The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
    • Wender, P. A., Mitchell, D. J., Pattabiraman, K., Pelkey, E. T., Steinman, L., and Rothbard, J. B. (2000) The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc. Natl. Acad. Sci. U. S. A. 97, 13003-13008.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 13003-13008
    • Wender, P.A.1    Mitchell, D.J.2    Pattabiraman, K.3    Pelkey, E.T.4    Steinman, L.5    Rothbard, J.B.6
  • 27
    • 0035542854 scopus 로고    scopus 로고
    • Molecular transporters for peptides: Delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7)
    • Chen, L., Wright, L. R., Chen, C. H., Oliver, S. F., Wender, P. A., and Mochly-Rosen, D. (2001) Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7). Chem. Biol. 8, 1123-1129.
    • (2001) Chem. Biol. , vol.8 , pp. 1123-1129
    • Chen, L.1    Wright, L.R.2    Chen, C.H.3    Oliver, S.F.4    Wender, P.A.5    Mochly-Rosen, D.6
  • 28
    • 0003009802 scopus 로고    scopus 로고
    • Modification of pre-mRNA splicing by antisense oligonucleotides
    • (Stein, C. A. M., Ed.), Wiley-Liss, Inc., New York
    • Kole, R. (1998) Modification of pre-mRNA splicing by antisense oligonucleotides. In Applied Antisense Oligonucleotides Technology (Stein, C. A. M., Ed.) pp 451-469, Wiley-Liss, Inc., New York.
    • (1998) Applied Antisense Oligonucleotides Technology , pp. 451-469
    • Kole, R.1
  • 29
    • 0029803547 scopus 로고    scopus 로고
    • Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides
    • Sierakowska, H., Sambade, M. J., Agrawal, S., and Kole, R. (1996) Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides. Proc. Natl. Acad. Sci. U. S. A. 93, 12840-12844.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 12840-12844
    • Sierakowska, H.1    Sambade, M.J.2    Agrawal, S.3    Kole, R.4
  • 32
    • 0032485884 scopus 로고    scopus 로고
    • Up-regulation of luciferase gene expression with antisense oligonucleotides: Implications and applications in functional assay development
    • Kang, S. H., Cho, M. J., and Kole, R. (1998) Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development. Biochemistry 37, 6235-6239.
    • (1998) Biochemistry , vol.37 , pp. 6235-6239
    • Kang, S.H.1    Cho, M.J.2    Kole, R.3
  • 34
    • 1642396643 scopus 로고    scopus 로고
    • (1991). Uncharged morpholino-based polymers having phosphorus containing chiral intersubunit linkages. US Patent 5185444
    • Summerton, J., and Weller, D. (1991). Uncharged morpholino-based polymers having phosphorus containing chiral intersubunit linkages. US Patent 5185444.
    • Summerton, J.1    Weller, D.2
  • 35
    • 0038814141 scopus 로고    scopus 로고
    • Peptide-assisted delivery of steric-blocking antisense oligomers
    • Moulton, H. M., and Moulton, J. D. (2003) Peptide-assisted delivery of steric-blocking antisense oligomers. Curr. Opin. Mol. Ther. 5, 123-132.
    • (2003) Curr. Opin. Mol. Ther. , vol.5 , pp. 123-132
    • Moulton, H.M.1    Moulton, J.D.2
  • 36
    • 0037169486 scopus 로고    scopus 로고
    • Possible existence of common internalization mechanisms among arginine-rich peptides
    • Suzuki, T., Futaki, S., Niwa, M., Tanaka, S., Ueda, K., and Sugiura, Y. (2002) Possible existence of common internalization mechanisms among arginine-rich peptides. J. Biol. Chem. 277, 2437-2443.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2437-2443
    • Suzuki, T.1    Futaki, S.2    Niwa, M.3    Tanaka, S.4    Ueda, K.5    Sugiura, Y.6
  • 37
    • 0037103242 scopus 로고    scopus 로고
    • Arginine-rich molecular transporters for drug delivery: Role of backbone spacing in cellular uptake
    • Rothbard, J. B., Kreider, E., VanDeusen, C. L., Wright, L., Wylie, B. L., and Wender, P. A. (2002) Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake. J. Med. Chem. 45, 3612-3618.
    • (2002) J. Med. Chem. , vol.45 , pp. 3612-3618
    • Rothbard, J.B.1    Kreider, E.2    VanDeusen, C.L.3    Wright, L.4    Wylie, B.L.5    Wender, P.A.6
  • 38
    • 0037172801 scopus 로고    scopus 로고
    • Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membrane-permeable peptides
    • Futaki, S., Nakase, I., Suzuki, T., Youjun, Z., and Sugiura, Y. (2002) Translocation of branched-chain arginine peptides through cell membranes: flexibility in the spatial disposition of positive charges in membrane-permeable peptides. Biochemistry 41, 7925-7930.
    • (2002) Biochemistry , vol.41 , pp. 7925-7930
    • Futaki, S.1    Nakase, I.2    Suzuki, T.3    Youjun, Z.4    Sugiura, Y.5
  • 39
    • 0025010857 scopus 로고
    • Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes
    • Feener, E. P., Shen, W. C., and Ryser, H. J. (1990) Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes. J. Biol. Chem. 265, 18780-18785.
    • (1990) J. Biol. Chem. , vol.265 , pp. 18780-18785
    • Feener, E.P.1    Shen, W.C.2    Ryser, H.J.3
  • 40
    • 0025946843 scopus 로고
    • Isolation of variants of Chinese hamster ovary cells with abnormally low levels of GSH: Decreased ability to cleave endocytosed disulfide bonds
    • Mandel, R., Ryser, H. J., Niaki, B., Ghani, F., and Shen, W. C. (1991) Isolation of variants of Chinese hamster ovary cells with abnormally low levels of GSH: decreased ability to cleave endocytosed disulfide bonds. J. Cell Physiol. 149, 60-65.
    • (1991) J. Cell Physiol. , vol.149 , pp. 60-65
    • Mandel, R.1    Ryser, H.J.2    Niaki, B.3    Ghani, F.4    Shen, W.C.5
  • 41
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: Delivery of a biologically active protein into the mouse
    • Schwarze, S. R., Ho, A., Vocero-Akbani, A., and Dowdy, S. F. (1999) In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285, 1569-1572.
    • (1999) Science , vol.285 , pp. 1569-1572
    • Schwarze, S.R.1    Ho, A.2    Vocero-Akbani, A.3    Dowdy, S.F.4
  • 42
    • 0034006169 scopus 로고    scopus 로고
    • Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
    • Lewin, M., Carlesso, N., Tung, C. H., Tang, X. W., Cory, D., Scadden, D. T., and Weissleder, R. (2000) Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat. Biotechnol. 18, 410-414.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 410-414
    • Lewin, M.1    Carlesso, N.2    Tung, C.H.3    Tang, X.W.4    Cory, D.5    Scadden, D.T.6    Weissleder, R.7


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