-
1
-
-
0030862707
-
Morpholino antisense oligomers: Design, preparation, and properties
-
Summerton, J., and Weller, D. (1997) Morpholino antisense oligomers: design, preparation, and properties. Antisense Nucleic Acid Drug Dev. 7, 187-195.
-
(1997)
Antisense Nucleic Acid Drug Dev.
, vol.7
, pp. 187-195
-
-
Summerton, J.1
Weller, D.2
-
2
-
-
0032699477
-
Morpholino antisense oligomers: The case for an RNase H-independent structural type
-
Summerton, J. (1999) Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochim. Biophys. Acta 1489, 141-158.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 141-158
-
-
Summerton, J.1
-
3
-
-
0030015872
-
In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis factor-alpha mRNA
-
Taylor, M. F., Paulauskis, J. D., Weller, D. D., and Kobzik, L. (1996) In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis factor-alpha mRNA. J. Biol. Chem. 271, 17445-17452.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17445-17452
-
-
Taylor, M.F.1
Paulauskis, J.D.2
Weller, D.D.3
Kobzik, L.4
-
4
-
-
0031239634
-
Comparison of efficacy of antisense oligomers directed toward TNF-alpha in helper T and macrophage cell lines
-
Taylor, M. F., Paulauskis, J. D., Weller, D. D., and Kobzik, L. (1997) Comparison of efficacy of antisense oligomers directed toward TNF-alpha in helper T and macrophage cell lines. Cytokine 9, 672-681.
-
(1997)
Cytokine
, vol.9
, pp. 672-681
-
-
Taylor, M.F.1
Paulauskis, J.D.2
Weller, D.D.3
Kobzik, L.4
-
5
-
-
0031828692
-
Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages
-
Taylor, M. F., Weller, D. D., and Kobzik, L. (1998) Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages. Antisense Nucleic Acid Drug Dev. 8, 199-205.
-
(1998)
Antisense Nucleic Acid Drug Dev.
, vol.8
, pp. 199-205
-
-
Taylor, M.F.1
Weller, D.D.2
Kobzik, L.3
-
6
-
-
0030969949
-
Morpholino and phosphorothioate antisense oligomers compared in cell-free and in-cell systems
-
Summerton, J., Stein, D., Huang, S. B., Matthews, P., Weller, D., and Partridge, M. (1997) Morpholino and phosphorothioate antisense oligomers compared in cell-free and in-cell systems. Antisense Nucleic Acid Drug Dev. 7, 63-70.
-
(1997)
Antisense Nucleic Acid Drug Dev.
, vol.7
, pp. 63-70
-
-
Summerton, J.1
Stein, D.2
Huang, S.B.3
Matthews, P.4
Weller, D.5
Partridge, M.6
-
7
-
-
0033916111
-
Antiproliferative effects of steric blocking phosphorodiamidate morpholino antisense agents directed against c-myc
-
Hudziak, R. M., Summerton, J., Weller, D. D., and Iversen, P. L. (2000) Antiproliferative effects of steric blocking phosphorodiamidate morpholino antisense agents directed against c-myc. Antisense Nucleic Acid Drug Dev. 10, 163-176.
-
(2000)
Antisense Nucleic Acid Drug Dev.
, vol.10
, pp. 163-176
-
-
Hudziak, R.M.1
Summerton, J.2
Weller, D.D.3
Iversen, P.L.4
-
8
-
-
0035181386
-
Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers
-
Stein, D. A., Skilling, D. E., Iversen, P. L., and Smith, A. W. (2001) Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers. Antisense Nucleic Acid Drug Dev. 11, 317-325.
-
(2001)
Antisense Nucleic Acid Drug Dev.
, vol.11
, pp. 317-325
-
-
Stein, D.A.1
Skilling, D.E.2
Iversen, P.L.3
Smith, A.W.4
-
9
-
-
33749208496
-
Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant
-
Nasevicius, A., Larson, J., and Ekker, S. C. (2000) Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast 17, 294-301.
-
(2000)
Yeast
, vol.17
, pp. 294-301
-
-
Nasevicius, A.1
Larson, J.2
Ekker, S.C.3
-
10
-
-
0034213262
-
Beta-catenin signaling activity dissected in the early Xenopus embryo: A novel antisense approach
-
Heasman, J., Kofron, M., and Wylie, C. (2000) Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach. Dev. Biol. 222, 124-134.
-
(2000)
Dev. Biol.
, vol.222
, pp. 124-134
-
-
Heasman, J.1
Kofron, M.2
Wylie, C.3
-
11
-
-
0035122848
-
SpKrl: A direct target of beta-catenin regulation required for endoderm differentiation in sea urchin embryos
-
Howard, E. W., Newman, L. A., Oleksyn, D. W., Angerer, R. C., and Angerer, L. M. (2001) SpKrl: a direct target of beta-catenin regulation required for endoderm differentiation in sea urchin embryos. Development 128, 365-375.
-
(2001)
Development
, vol.128
, pp. 365-375
-
-
Howard, E.W.1
Newman, L.A.2
Oleksyn, D.W.3
Angerer, R.C.4
Angerer, L.M.5
-
12
-
-
0035042293
-
The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos
-
Kos, R., Reedy, M. V., Johnson, R. L., and Erickson, C. A. (2001) The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. Development 128, 1467-1479.
-
(2001)
Development
, vol.128
, pp. 1467-1479
-
-
Kos, R.1
Reedy, M.V.2
Johnson, R.L.3
Erickson, C.A.4
-
13
-
-
0030475053
-
Resistance of morpholino phosphorodiamidate oligomers to enzymatic degradation
-
Hudziak, R. M., Barofsky, E., Barofsky, D. F., Weller, D. L., Huang, S. B., and Weller, D. D. (1996) Resistance of morpholino phosphorodiamidate oligomers to enzymatic degradation. Antisense Nucleic Acid Drug Dev 6, 267-272.
-
(1996)
Antisense Nucleic Acid Drug Dev.
, vol.6
, pp. 267-272
-
-
Hudziak, R.M.1
Barofsky, E.2
Barofsky, D.F.3
Weller, D.L.4
Huang, S.B.5
Weller, D.D.6
-
14
-
-
0033811705
-
Intracellular delivery strategies for antisense phosphorodiamidate morpholino oligomers
-
Ghosh, C., and Iversen, P. L. (2000) Intracellular delivery strategies for antisense phosphorodiamidate morpholino oligomers. Antisense Nucleic Acid Drug Dev. 10, 263-274.
-
(2000)
Antisense Nucleic Acid Drug Dev.
, vol.10
, pp. 263-274
-
-
Ghosh, C.1
Iversen, P.L.2
-
15
-
-
0034910904
-
Achieving efficient delivery of morpholino oligos in cultured cells
-
Morcos, P. A. (2001) Achieving efficient delivery of morpholino oligos in cultured cells. Genesis 30, 94-102.
-
(2001)
Genesis
, vol.30
, pp. 94-102
-
-
Morcos, P.A.1
-
16
-
-
0028054797
-
Tat-mediated delivery of heterologous proteins into cells
-
Fawell, S., Seery, J., Daikh, Y., Moore, C., Chen, L. L., Pepinsky, B., and Barsoum, J. (1994) Tat-mediated delivery of heterologous proteins into cells. Proc. Natl. Acad. Sci. U. S. A. 91, 664-668.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 664-668
-
-
Fawell, S.1
Seery, J.2
Daikh, Y.3
Moore, C.4
Chen, L.L.5
Pepinsky, B.6
Barsoum, J.7
-
17
-
-
0028239908
-
The third helix of the Antennapedia homeodomain translocates through biological membranes
-
Derossi, D., Joliot, A. H., Chassaing, G., and Prochiantz, A. (1994) The third helix of the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem. 269, 10444-10450.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10444-10450
-
-
Derossi, D.1
Joliot, A.H.2
Chassaing, G.3
Prochiantz, A.4
-
18
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vives, E., Brodin, P., and Lebleu, B. (1997) A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272, 16010-16017.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16010-16017
-
-
Vives, E.1
Brodin, P.2
Lebleu, B.3
-
19
-
-
0031754150
-
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo
-
Pooga, M., Soomets, U., Hallbrink, M., Valkna, A., Saar, K., Rezaei, K., Kahl, U., Hao, J. X., Xu, X. J., Wiesenfeld-Hallin, Z., Hokfelt, T., Bartfai, T., and Langel, U. (1998) Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat. Biotechnol. 16, 857-861.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 857-861
-
-
Pooga, M.1
Soomets, U.2
Hallbrink, M.3
Valkna, A.4
Saar, K.5
Rezaei, K.6
Kahl, U.7
Hao, J.X.8
Xu, X.J.9
Wiesenfeld-Hallin, Z.10
Hokfelt, T.11
Bartfai, T.12
Langel, U.13
-
20
-
-
0035989846
-
Cell-dependent differential cellular uptake of PNA, peptides, and PNA-peptide conjugates
-
Koppelhus, U., Awasthi, S. K., Zachar, V., Holst, H. U., Ebbesen, P., and Nielsen, P. E. (2002) Cell-dependent differential cellular uptake of PNA, peptides, and PNA-peptide conjugates. Antisense Nucleic Acid Drug Dev. 12, 51-63.
-
(2002)
Antisense Nucleic Acid Drug Dev.
, vol.12
, pp. 51-63
-
-
Koppelhus, U.1
Awasthi, S.K.2
Zachar, V.3
Holst, H.U.4
Ebbesen, P.5
Nielsen, P.E.6
-
21
-
-
0346460957
-
Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake
-
Richard, J. P., Melikov, K., Vives, E., Ramos, C., Verbeure, B., Gait, M. J., Chernomordik, L. V., and Lebleu, B. (2003) Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J. Biol. Chem. 278, 585-590.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
Melikov, K.2
Vives, E.3
Ramos, C.4
Verbeure, B.5
Gait, M.J.6
Chernomordik, L.V.7
Lebleu, B.8
-
22
-
-
0034640463
-
Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells
-
Villa, R., Folini, M., Lualdi, S., Veronese, S., Daidone, M. G., and Zaffaroni, N. (2000) Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells. FEBS Lett. 473, 241-248.
-
(2000)
FEBS Lett.
, vol.473
, pp. 241-248
-
-
Villa, R.1
Folini, M.2
Lualdi, S.3
Veronese, S.4
Daidone, M.G.5
Zaffaroni, N.6
-
23
-
-
0035863391
-
Synthetic protein transduction domains: Enhanced transduction potential in vitro and in vivo
-
Ho, A., Schwarze, S. R., Mermelstein, S. J., Waksman, G., and Dowdy, S. F. (2001) Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo. Cancer Res. 61, 474-477.
-
(2001)
Cancer Res.
, vol.61
, pp. 474-477
-
-
Ho, A.1
Schwarze, S.R.2
Mermelstein, S.J.3
Waksman, G.4
Dowdy, S.F.5
-
24
-
-
0037302448
-
HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers
-
Moulton, H. M., Hase, M. C., Smith, K. M., and Iversen, P. L. (2003) HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers. Antisense Nucleic Acid Drug Dev. 13, 31-43.
-
(2003)
Antisense Nucleic Acid Drug Dev.
, vol.13
, pp. 31-43
-
-
Moulton, H.M.1
Hase, M.C.2
Smith, K.M.3
Iversen, P.L.4
-
25
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
-
Wender, P. A., Mitchell, D. J., Pattabiraman, K., Pelkey, E. T., Steinman, L., and Rothbard, J. B. (2000) The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc. Natl. Acad. Sci. U. S. A. 97, 13003-13008.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
Mitchell, D.J.2
Pattabiraman, K.3
Pelkey, E.T.4
Steinman, L.5
Rothbard, J.B.6
-
26
-
-
0035210533
-
Stearylated arginine-rich peptides: A new class of transfection systems
-
Futaki, S., Ohashi, W., Suzuki, T., Niwa, M., Tanaka, S., Ueda, K., Harashima, H., and Sugiura, Y. (2001) Stearylated arginine-rich peptides: a new class of transfection systems. Bioconjugate Chem. 12, 1005-1011.
-
(2001)
Bioconjugate Chem.
, vol.12
, pp. 1005-1011
-
-
Futaki, S.1
Ohashi, W.2
Suzuki, T.3
Niwa, M.4
Tanaka, S.5
Ueda, K.6
Harashima, H.7
Sugiura, Y.8
-
27
-
-
0035542854
-
Molecular transporters for peptides: Delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7)
-
Chen, L., Wright, L. R., Chen, C. H., Oliver, S. F., Wender, P. A., and Mochly-Rosen, D. (2001) Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7). Chem. Biol. 8, 1123-1129.
-
(2001)
Chem. Biol.
, vol.8
, pp. 1123-1129
-
-
Chen, L.1
Wright, L.R.2
Chen, C.H.3
Oliver, S.F.4
Wender, P.A.5
Mochly-Rosen, D.6
-
28
-
-
0003009802
-
Modification of pre-mRNA splicing by antisense oligonucleotides
-
(Stein, C. A. M., Ed.), Wiley-Liss, Inc., New York
-
Kole, R. (1998) Modification of pre-mRNA splicing by antisense oligonucleotides. In Applied Antisense Oligonucleotides Technology (Stein, C. A. M., Ed.) pp 451-469, Wiley-Liss, Inc., New York.
-
(1998)
Applied Antisense Oligonucleotides Technology
, pp. 451-469
-
-
Kole, R.1
-
29
-
-
0029803547
-
Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides
-
Sierakowska, H., Sambade, M. J., Agrawal, S., and Kole, R. (1996) Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides. Proc. Natl. Acad. Sci. U. S. A. 93, 12840-12844.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 12840-12844
-
-
Sierakowska, H.1
Sambade, M.J.2
Agrawal, S.3
Kole, R.4
-
30
-
-
0034662881
-
Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients
-
Lacerra, G., Sierakowska, H., Carestia, C., Fucharoen, S., Summerton, J., Weller, D., and Kole, R. (2000) Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients. Proc. Natl. Acad. Sci. U. S. A. 97, 9591-9596.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 9591-9596
-
-
Lacerra, G.1
Sierakowska, H.2
Carestia, C.3
Fucharoen, S.4
Summerton, J.5
Weller, D.6
Kole, R.7
-
31
-
-
0035477551
-
Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs
-
Sazani, P., Kang, S. H., Maier, M. A., Wei, C., Dillman, J., Summerton, J., Manoharan, M., and Kole, R. (2001) Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs. Nucleic Acids Res. 29, 3965-3974.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 3965-3974
-
-
Sazani, P.1
Kang, S.H.2
Maier, M.A.3
Wei, C.4
Dillman, J.5
Summerton, J.6
Manoharan, M.7
Kole, R.8
-
32
-
-
0032485884
-
Up-regulation of luciferase gene expression with antisense oligonucleotides: Implications and applications in functional assay development
-
Kang, S. H., Cho, M. J., and Kole, R. (1998) Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development. Biochemistry 37, 6235-6239.
-
(1998)
Biochemistry
, vol.37
, pp. 6235-6239
-
-
Kang, S.H.1
Cho, M.J.2
Kole, R.3
-
33
-
-
0036903132
-
Systemically delivered antisense oligomers upregulate gene expression in mouse tissues
-
Sazani, P., Gemignani, F., Kang, S. H., Maier, M. A., Manoharan, M., Persmark, M., Bortner, D., and Kole, R. (2002) Systemically delivered antisense oligomers upregulate gene expression in mouse tissues. Nat. Biotechnol. 20, 1228-1233.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 1228-1233
-
-
Sazani, P.1
Gemignani, F.2
Kang, S.H.3
Maier, M.A.4
Manoharan, M.5
Persmark, M.6
Bortner, D.7
Kole, R.8
-
34
-
-
1642396643
-
-
(1991). Uncharged morpholino-based polymers having phosphorus containing chiral intersubunit linkages. US Patent 5185444
-
Summerton, J., and Weller, D. (1991). Uncharged morpholino-based polymers having phosphorus containing chiral intersubunit linkages. US Patent 5185444.
-
-
-
Summerton, J.1
Weller, D.2
-
35
-
-
0038814141
-
Peptide-assisted delivery of steric-blocking antisense oligomers
-
Moulton, H. M., and Moulton, J. D. (2003) Peptide-assisted delivery of steric-blocking antisense oligomers. Curr. Opin. Mol. Ther. 5, 123-132.
-
(2003)
Curr. Opin. Mol. Ther.
, vol.5
, pp. 123-132
-
-
Moulton, H.M.1
Moulton, J.D.2
-
36
-
-
0037169486
-
Possible existence of common internalization mechanisms among arginine-rich peptides
-
Suzuki, T., Futaki, S., Niwa, M., Tanaka, S., Ueda, K., and Sugiura, Y. (2002) Possible existence of common internalization mechanisms among arginine-rich peptides. J. Biol. Chem. 277, 2437-2443.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2437-2443
-
-
Suzuki, T.1
Futaki, S.2
Niwa, M.3
Tanaka, S.4
Ueda, K.5
Sugiura, Y.6
-
37
-
-
0037103242
-
Arginine-rich molecular transporters for drug delivery: Role of backbone spacing in cellular uptake
-
Rothbard, J. B., Kreider, E., VanDeusen, C. L., Wright, L., Wylie, B. L., and Wender, P. A. (2002) Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake. J. Med. Chem. 45, 3612-3618.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 3612-3618
-
-
Rothbard, J.B.1
Kreider, E.2
VanDeusen, C.L.3
Wright, L.4
Wylie, B.L.5
Wender, P.A.6
-
38
-
-
0037172801
-
Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membrane-permeable peptides
-
Futaki, S., Nakase, I., Suzuki, T., Youjun, Z., and Sugiura, Y. (2002) Translocation of branched-chain arginine peptides through cell membranes: flexibility in the spatial disposition of positive charges in membrane-permeable peptides. Biochemistry 41, 7925-7930.
-
(2002)
Biochemistry
, vol.41
, pp. 7925-7930
-
-
Futaki, S.1
Nakase, I.2
Suzuki, T.3
Youjun, Z.4
Sugiura, Y.5
-
39
-
-
0025010857
-
Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes
-
Feener, E. P., Shen, W. C., and Ryser, H. J. (1990) Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes. J. Biol. Chem. 265, 18780-18785.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 18780-18785
-
-
Feener, E.P.1
Shen, W.C.2
Ryser, H.J.3
-
40
-
-
0025946843
-
Isolation of variants of Chinese hamster ovary cells with abnormally low levels of GSH: Decreased ability to cleave endocytosed disulfide bonds
-
Mandel, R., Ryser, H. J., Niaki, B., Ghani, F., and Shen, W. C. (1991) Isolation of variants of Chinese hamster ovary cells with abnormally low levels of GSH: decreased ability to cleave endocytosed disulfide bonds. J. Cell Physiol. 149, 60-65.
-
(1991)
J. Cell Physiol.
, vol.149
, pp. 60-65
-
-
Mandel, R.1
Ryser, H.J.2
Niaki, B.3
Ghani, F.4
Shen, W.C.5
-
41
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze, S. R., Ho, A., Vocero-Akbani, A., and Dowdy, S. F. (1999) In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285, 1569-1572.
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
42
-
-
0034006169
-
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
-
Lewin, M., Carlesso, N., Tung, C. H., Tang, X. W., Cory, D., Scadden, D. T., and Weissleder, R. (2000) Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat. Biotechnol. 18, 410-414.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 410-414
-
-
Lewin, M.1
Carlesso, N.2
Tung, C.H.3
Tang, X.W.4
Cory, D.5
Scadden, D.T.6
Weissleder, R.7
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