-
2
-
-
0033853732
-
New insights into hepatic stellate cell activation: The simple becomes complex
-
Eng FJ, Friedman SL. New insights into hepatic stellate cell activation: the simple becomes complex. Am J Physiol Gastrointest Liver Physiol 2000;279:G7-11.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
-
-
Eng, F.J.1
Friedman, S.L.2
-
3
-
-
0036784417
-
Beauty is in the eye of the beholder: Emerging concepts and pitfalls in hepatic stellate cell research
-
Cassiman D, Roskams T. Beauty is in the eye of the beholder: emerging concepts and pitfalls in hepatic stellate cell research. J Hepatol 2002;37:527-35.
-
(2002)
J Hepatol
, vol.37
, pp. 527-535
-
-
Cassiman, D.1
Roskams, T.2
-
4
-
-
0034723290
-
Molecular regulation of hepatic fibrosis, and integrated cellular response to tissue injury
-
Friedman SL. Molecular regulation of hepatic fibrosis, and integrated cellular response to tissue injury. J Biol Chem 2000;275:2247-50.
-
(2000)
J Biol Chem
, vol.275
, pp. 2247-2250
-
-
Friedman, S.L.1
-
5
-
-
0023574686
-
Biochemical characteristics of isolated rat liver stellate cells
-
Yamada M, Blaner WS, Soprano DR, Dixon JL, Kjeldbye HM, Goodman DS. Biochemical characteristics of isolated rat liver stellate cells. Hepatology 1987;7:1224-9.
-
(1987)
Hepatology
, vol.7
, pp. 1224-1229
-
-
Yamada, M.1
Blaner, W.S.2
Soprano, D.R.3
Dixon, J.L.4
Kjeldbye, H.M.5
Goodman, D.S.6
-
6
-
-
0024215032
-
Effects of dietary retinoid and triglyceride on the lipid composition of rat liver stellate cells and stellate cell lipid droplets
-
Moriwaki H, Blaner WS, Piantedosi R, Goodman DS. Effects of dietary retinoid and triglyceride on the lipid composition of rat liver stellate cells and stellate cell lipid droplets. J Lipid Res 1988;29:1523-34.
-
(1988)
J Lipid Res
, vol.29
, pp. 1523-1534
-
-
Moriwaki, H.1
Blaner, W.S.2
Piantedosi, R.3
Goodman, D.S.4
-
7
-
-
0036551274
-
Activation of hepatic stellate cells-a key issue in liver fibrosis
-
Reeves HL, Friedman SL. Activation of hepatic stellate cells-a key issue in liver fibrosis. Front Biosci 2002;7: d808-26.
-
(2002)
Front Biosci
, vol.7
-
-
Reeves, H.L.1
Friedman, S.L.2
-
8
-
-
0042322996
-
Obesity and its nurturing effect on hepatitis C
-
McCullough AJ. Obesity and its nurturing effect on hepatitis C. Hepatology 2003;38:557-9.
-
(2003)
Hepatology
, vol.38
, pp. 557-559
-
-
McCullough, A.J.1
-
9
-
-
0034116558
-
Liver fibrosis in overweight patients
-
Ratziu V, Giral P, Charlotte F, Bruckert E, Thibault V, Theodorou I, Khalil L, Turpin G, Opolon P, Poynard T. Liver fibrosis in overweight patients. Gastroenterology 2000;118:1117-23.
-
(2000)
Gastroenterology
, vol.118
, pp. 1117-1123
-
-
Ratziu, V.1
Giral, P.2
Charlotte, F.3
Bruckert, E.4
Thibault, V.5
Theodorou, I.6
Khalil, L.7
Turpin, G.8
Opolon, P.9
Poynard, T.10
-
10
-
-
0016915956
-
Epidemiology of alcoholic liver disease
-
Popper H, Schaffner F, eds. Philadelphia: Grune and Stratton
-
Lelbach WK. Epidemiology of alcoholic liver disease. In: Popper H, Schaffner F, eds. Progress in Liver Diseases. Philadelphia: Grune and Stratton, 1976:434-515.
-
(1976)
Progress in Liver Diseases
, pp. 434-515
-
-
Lelbach, W.K.1
-
11
-
-
0031012322
-
Excess weight risk factor for alcoholic liver disease
-
Naveau S, Giraud V, Borotto E, Aubert A, Capron F, Chaput J-C. Excess weight risk factor for alcoholic liver disease. Hepatology 1997;25:108-11.
-
(1997)
Hepatology
, vol.25
, pp. 108-111
-
-
Naveau, S.1
Giraud, V.2
Borotto, E.3
Aubert, A.4
Capron, F.5
Chaput, J.-C.6
-
12
-
-
0025260531
-
Fatty liver hepatitis (steatohepatitis) and obesity: An autopsy study with analysis of risk factors
-
Wanless IR, Lentz JS. Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors. Hepatology 1990;12:1106-10.
-
(1990)
Hepatology
, vol.12
, pp. 1106-1110
-
-
Wanless, I.R.1
Lentz, J.S.2
-
13
-
-
0028875908
-
The natural history of nonalcoholic fatty liver: A follow-up study
-
Teli MR, James OF, Burt AD, Bennett MK, Day CP. The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 1995;22:1714-9.
-
(1995)
Hepatology
, vol.22
, pp. 1714-1719
-
-
Teli, M.R.1
James, O.F.2
Burt, A.D.3
Bennett, M.K.4
Day, C.P.5
-
14
-
-
0032695030
-
Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
-
Angulo P, Keach JC, Batts KP, Lindor KD. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 1999;30:1356-62.
-
(1999)
Hepatology
, vol.30
, pp. 1356-1362
-
-
Angulo, P.1
Keach, J.C.2
Batts, K.P.3
Lindor, K.D.4
-
15
-
-
0038644536
-
Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
-
Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology 2003;37:1202-19.
-
(2003)
Hepatology
, vol.37
, pp. 1202-1219
-
-
Neuschwander-Tetri, B.A.1
Caldwell, S.H.2
-
16
-
-
0032924020
-
Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis
-
Hourigan LF, Macdonald GA, Purdie D, Whitehall VH, Shorthouse C, Clouston A, Powell EE. Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis. Hepatology 1999;29:1215-9.
-
(1999)
Hepatology
, vol.29
, pp. 1215-1219
-
-
Hourigan, L.F.1
Macdonald, G.A.2
Purdie, D.3
Whitehall, V.H.4
Shorthouse, C.5
Clouston, A.6
Powell, E.E.7
-
17
-
-
0043037223
-
High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C
-
Bressler BL, Guindi M, Tomlinson G, Heathcote J. High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C. Hepatology 2003;38:639-44.
-
(2003)
Hepatology
, vol.38
, pp. 639-644
-
-
Bressler, B.L.1
Guindi, M.2
Tomlinson, G.3
Heathcote, J.4
-
18
-
-
0025367559
-
Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?
-
Haffner SM, Stern MP, Hazuda HP, Mitchell BD, Patterson JK. Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes? JAMA 1990;263:2893-8.
-
(1990)
JAMA
, vol.263
, pp. 2893-2898
-
-
Haffner, S.M.1
Stern, M.P.2
Hazuda, H.P.3
Mitchell, B.D.4
Patterson, J.K.5
-
19
-
-
0345059390
-
Insulin resistance and tissue repair: A "fatological" phenomenon
-
Sanyal AJ. Insulin resistance and tissue repair: a " fatological" phenomenon. Gastroenterology 2003;125:1886-9.
-
(2003)
Gastroenterology
, vol.125
, pp. 1886-1889
-
-
Sanyal, A.J.1
-
20
-
-
0345655291
-
Insulin resistance is associated with chronic hepatitis C and virus infection fibrosis progression
-
Hui JM, Sud A, Farrell GC, Bandara P, Byth K, Kench JG, McCaughan GM, George J. Insulin resistance is associated with chronic hepatitis C and virus infection fibrosis progression. Gastroenterology 2003;125:1695-704.
-
(2003)
Gastroenterology
, vol.125
, pp. 1695-1704
-
-
Hui, J.M.1
Sud, A.2
Farrell, G.C.3
Bandara, P.4
Byth, K.5
Kench, J.G.6
McCaughan, G.M.7
George, J.8
-
21
-
-
0037349674
-
Glucose intolerance in Chinese patients with chronic hepatitis C
-
Chen LK, Hwang SJ, Tsai ST, Luo JC, Lee SD, Chang FY. Glucose intolerance in Chinese patients with chronic hepatitis C. World J Gastroenterol 2003;9:505-8.
-
(2003)
World J Gastroenterol
, vol.9
, pp. 505-508
-
-
Chen, L.K.1
Hwang, S.J.2
Tsai, S.T.3
Luo, J.C.4
Lee, S.D.5
Chang, F.Y.6
-
22
-
-
0036294003
-
Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C
-
Hickman IJ, Clouston AD, Macdonald GA, Purdie DM, Prins JB, Ash S, Jonsson JR, Powell EE. Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C. Gut 2002;51:89-94.
-
(2002)
Gut
, vol.51
, pp. 89-94
-
-
Hickman, I.J.1
Clouston, A.D.2
Macdonald, G.A.3
Purdie, D.M.4
Prins, J.B.5
Ash, S.6
Jonsson, J.R.7
Powell, E.E.8
-
23
-
-
0037356826
-
The role of the novel adipocyte-derived hormone adiponectin in human disease
-
Diez JD, Iglesias P. The role of the novel adipocyte-derived hormone adiponectin in human disease. Europ J Endocrin 2003;148:293-300.
-
(2003)
Europ J Endocrin
, vol.148
, pp. 293-300
-
-
Diez, J.D.1
Iglesias, P.2
-
24
-
-
0032994264
-
Insulin and insulin-like growth factor-1 stimulate proliferation and type I collagen accumulation by human hepatic stellate cells: Differential effects on signal transduction pathways
-
Svegliati-Baroni G, Ridolfi F, Di Sario A, Cassini A, Marucci L, Gaggiotti G, Orlandoni P, Macarri G, Perego L, Benedetti A, Folli F. Insulin and insulin-like growth factor-1 stimulate proliferation and type I collagen accumulation by human hepatic stellate cells: differential effects on signal transduction pathways. Hepatology 1999;29:1743-51.
-
(1999)
Hepatology
, vol.29
, pp. 1743-1751
-
-
Svegliati-Baroni, G.1
Ridolfi, F.2
Di Sario, A.3
Cassini, A.4
Marucci, L.5
Gaggiotti, G.6
Orlandoni, P.7
Macarri, G.8
Perego, L.9
Benedetti, A.10
Folli, F.11
-
25
-
-
0034802171
-
High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis
-
Paradis V, Perlemuter G, Bonvoust F, Dargere D, Parfait B, Vidaud M, Conti M, Huet S, Ba N, Buffet C, Bedossa P. High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis. Hepatology 2001;34:738-44.
-
(2001)
Hepatology
, vol.34
, pp. 738-744
-
-
Paradis, V.1
Perlemuter, G.2
Bonvoust, F.3
Dargere, D.4
Parfait, B.5
Vidaud, M.6
Conti, M.7
Huet, S.8
Ba, N.9
Buffet, C.10
Bedossa, P.11
-
26
-
-
0029994141
-
High insulin-like growth factor binding protein 1 levels in cirrhosis: Link with insulin resistance
-
Shmueli E, Miell JP, Stewart M, Alberti KG, Record CO. High insulin-like growth factor binding protein 1 levels in cirrhosis: link with insulin resistance. Hepatology 1996; 24:127-33.
-
(1996)
Hepatology
, vol.24
, pp. 127-133
-
-
Shmueli, E.1
Miell, J.P.2
Stewart, M.3
Alberti, K.G.4
Record, C.O.5
-
27
-
-
0036623365
-
Regulation of the growth hormone receptor/binding protein, insulin-like growth factor ternary complex system in human cirrhosis
-
Donaghy AJ, Delhanty PJ, Ho KK, Williams R, Baxter RC. Regulation of the growth hormone receptor/binding protein, insulin-like growth factor ternary complex system in human cirrhosis. J Hepatol 2002;36:751-8.
-
(2002)
J Hepatol
, vol.36
, pp. 751-758
-
-
Donaghy, A.J.1
Delhanty, P.J.2
Ho, K.K.3
Williams, R.4
Baxter, R.C.5
-
28
-
-
0030817309
-
Hepatoprotective effects of insulin-like growth factor I in rats with carbon tetrachloride-induced cirrhosis
-
Castilla-Cortazar I, Garcia M, Muguerza B, Quiroga J, Perez R, Santidrian S, Prieto J. Hepatoprotective effects of insulin-like growth factor I in rats with carbon tetrachloride-induced cirrhosis. Gastroenterology 1997;113: 1682-91.
-
(1997)
Gastroenterology
, vol.113
, pp. 1682-1691
-
-
Castilla-Cortazar, I.1
Garcia, M.2
Muguerza, B.3
Quiroga, J.4
Perez, R.5
Santidrian, S.6
Prieto, J.7
-
29
-
-
0030806552
-
Impaired intestinal sugar transport in cirrhotic rats: Correction by low doses of insulin-like growth factor I
-
Castilla-Cortazar I, Prieto J, Urdaneta E, Pascual M, Nunez M, Zudaire E, Garcia M, Quiroga J, Santidrian S. Impaired intestinal sugar transport in cirrhotic rats: correction by low doses of insulin-like growth factor I. Gastroenterology 1997;113:1180-7.
-
(1997)
Gastroenterology
, vol.113
, pp. 1180-1187
-
-
Castilla-Cortazar, I.1
Prieto, J.2
Urdaneta, E.3
Pascual, M.4
Nunez, M.5
Zudaire, E.6
Garcia, M.7
Quiroga, J.8
Santidrian, S.9
-
30
-
-
0035078484
-
Etiopathogenesis of nonalcoholic steatohepatitis
-
Chitturi S, Farrell GC. Etiopathogenesis of nonalcoholic steatohepatitis. Semin Liver Dis 2001;21:27-41.
-
(2001)
Semin Liver Dis
, vol.21
, pp. 27-41
-
-
Chitturi, S.1
Farrell, G.C.2
-
31
-
-
0034950652
-
Nonalcoholic fatty liver disease: Predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese
-
Dixon JB, Bhathal PS, O'Brien PE. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology 2001;121:91-100.
-
(2001)
Gastroenterology
, vol.121
, pp. 91-100
-
-
Dixon, J.B.1
Bhathal, P.S.2
O'Brien, P.E.3
-
32
-
-
18244364864
-
NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome
-
Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui JM, Fung C, Karim R, Lin R, Samarasinghe D, Liddle C, Weltman M, George J. NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 2002; 35:373-9.
-
(2002)
Hepatology
, vol.35
, pp. 373-379
-
-
Chitturi, S.1
Abeygunasekera, S.2
Farrell, G.C.3
Holmes-Walker, J.4
Hui, J.M.5
Fung, C.6
Karim, R.7
Lin, R.8
Samarasinghe, D.9
Liddle, C.10
Weltman, M.11
George, J.12
-
33
-
-
0034862555
-
Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C
-
Petit JM, Bour JB, Galland-Jos C, Minello A, Verges B, Guiguet M, Brun JM, Hillon P. Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C. J Hepatol 2001;35:279-83.
-
(2001)
J Hepatol
, vol.35
, pp. 279-283
-
-
Petit, J.M.1
Bour, J.B.2
Galland-Jos, C.3
Minello, A.4
Verges, B.5
Guiguet, M.6
Brun, J.M.7
Hillon, P.8
-
34
-
-
0141532275
-
Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
-
Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Oliver D, Bacon BR. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology 2003;38:1008-17.
-
(2003)
Hepatology
, vol.38
, pp. 1008-1017
-
-
Neuschwander-Tetri, B.A.1
Brunt, E.M.2
Wehmeier, K.R.3
Oliver, D.4
Bacon, B.R.5
-
35
-
-
0037900979
-
Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
-
Lee CH, Olson P, Evans RM. Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology 2003;144:2201-7.
-
(2003)
Endocrinology
, vol.144
, pp. 2201-2207
-
-
Lee, C.H.1
Olson, P.2
Evans, R.M.3
-
36
-
-
0034076888
-
The role of hepatic peroxisome proliferator-activated receptors (PPARs) in health and disease
-
Everett L, Galli A, Crabb D. The role of hepatic peroxisome proliferator-activated receptors (PPARs) in health and disease. Liver 2000;20:191-9.
-
(2000)
Liver
, vol.20
, pp. 191-199
-
-
Everett, L.1
Galli, A.2
Crabb, D.3
-
37
-
-
0033855572
-
Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells
-
Marra F, Efsen E, Romanelli RG, Caligiuri A, Pastacaldi S, Batignani G, Bonacchi A, Caporale R, Laffi G, Pinzani M, Gentilini P. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. Gastroenterology 2000;119:466-78.
-
(2000)
Gastroenterology
, vol.119
, pp. 466-478
-
-
Marra, F.1
Efsen, E.2
Romanelli, R.G.3
Caligiuri, A.4
Pastacaldi, S.5
Batignani, G.6
Bonacchi, A.7
Caporale, R.8
Laffi, G.9
Pinzani, M.10
Gentilini, P.11
-
38
-
-
0037663778
-
Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth
-
Xu J, Fu Y, Chen A. Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth. Am J Physiol Gastrointest Liver Physiol 2003;285:G20-30.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.285
-
-
Xu, J.1
Fu, Y.2
Chen, A.3
-
39
-
-
0036082703
-
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
-
Galli A, Crabb DW, Ceni E, Salzano R, Mello T, Svegliati-Baroni G, Ridolfi F, Trozzi L, Surrenti C, Casini A. Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. Gastroenterology 2002;122:1924-40.
-
(2002)
Gastroenterology
, vol.122
, pp. 1924-1940
-
-
Galli, A.1
Crabb, D.W.2
Ceni, E.3
Salzano, R.4
Mello, T.5
Svegliati-Baroni, G.6
Ridolfi, F.7
Trozzi, L.8
Surrenti, C.9
Casini, A.10
-
40
-
-
0037221210
-
Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells
-
Hellemans K, Michalik L, Dittie A, Knorr A, Rombouts K, De Jong J, Heirman C, Quartier E, Schuit F, Wahli W, Geerts A. Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells. Gastroenterology 2003;124:184-201.
-
(2003)
Gastroenterology
, vol.124
, pp. 184-201
-
-
Hellemans, K.1
Michalik, L.2
Dittie, A.3
Knorr, A.4
Rombouts, K.5
De Jong, J.6
Heirman, C.7
Quartier, E.8
Schuit, F.9
Wahli, W.10
Geerts, A.11
-
41
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-32.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
43
-
-
0030866843
-
Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans
-
Masuzaki H, Ogawa Y, Sagawa N, Hosoda K, Matsumoto T, Mise H, Nishimura H, Yoshimasa Y, Tanaka I, Mori T, Nakao K. Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat Med 1997;3:1029-33.
-
(1997)
Nat Med
, vol.3
, pp. 1029-1033
-
-
Masuzaki, H.1
Ogawa, Y.2
Sagawa, N.3
Hosoda, K.4
Matsumoto, T.5
Mise, H.6
Nishimura, H.7
Yoshimasa, Y.8
Tanaka, I.9
Mori, T.10
Nakao, K.11
-
44
-
-
0032489223
-
Transdifferentiation of rat hepatic stellate cells results in leptin expression
-
Potter JJ, Womack L, Mezey E, Anania FA. Transdifferentiation of rat hepatic stellate cells results in leptin expression. Biochem Biophys Res Commun 1998; 244:178-82.
-
(1998)
Biochem Biophys Res Commun
, vol.244
, pp. 178-182
-
-
Potter, J.J.1
Womack, L.2
Mezey, E.3
Anania, F.A.4
-
46
-
-
0033023477
-
Increased circulating leptin in alcoholic cirrhosis: Relation to release and disposal
-
Henriksen JH, Holst JJ, Moller S, Brinch K, Bendtsen F. Increased circulating leptin in alcoholic cirrhosis: relation to release and disposal. Hepatology 1999;29:1818-24.
-
(1999)
Hepatology
, vol.29
, pp. 1818-1824
-
-
Henriksen, J.H.1
Holst, J.J.2
Moller, S.3
Brinch, K.4
Bendtsen, F.5
-
47
-
-
0034465579
-
Elevated bound leptin correlates with energy expenditure in cirrhotics
-
Ockenga J, Bischoff SC, Tillmann HL, Rifai K, Widjaja A, Boker KH, Manns MP, Brabant G. Elevated bound leptin correlates with energy expenditure in cirrhotics. Gastroenterology 2000;119:1656-62.
-
(2000)
Gastroenterology
, vol.119
, pp. 1656-1662
-
-
Ockenga, J.1
Bischoff, S.C.2
Tillmann, H.L.3
Rifai, K.4
Widjaja, A.5
Boker, K.H.6
Manns, M.P.7
Brabant, G.8
-
48
-
-
10744231005
-
The severity of liver fibrosis is associated with high leptin levels in chronic hepatitis C
-
Piche T, Vandenbos F, Abakar-Mahamat A, Vanbiervliet G, Barjoan EM, Calle G, Giudicelli J, Ferrua B, Laffont C, Benzaken S, Tran A. The severity of liver fibrosis is associated with high leptin levels in chronic hepatitis C. J Viral Hepat 2004;11:91-6.
-
(2004)
J Viral Hepat
, vol.11
, pp. 91-96
-
-
Piche, T.1
Vandenbos, F.2
Abakar-Mahamat, A.3
Vanbiervliet, G.4
Barjoan, E.M.5
Calle, G.6
Giudicelli, J.7
Ferrua, B.8
Laffont, C.9
Benzaken, S.10
Tran, A.11
-
49
-
-
0036329894
-
Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: A manifestation of lipotoxicity?
-
Chitturi S, Farrell G, Frost L, Kriketos A, Lin R, Fung C, Liddle C, Samarasinghe D, George J. Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity? Hepatology 2002;36:403-9.
-
(2002)
Hepatology
, vol.36
, pp. 403-409
-
-
Chitturi, S.1
Farrell, G.2
Frost, L.3
Kriketos, A.4
Lin, R.5
Fung, C.6
Liddle, C.7
Samarasinghe, D.8
George, J.9
-
50
-
-
0034927064
-
Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals
-
Ikejima K, Honda H, Yoshikawa M, Hirose M, Kitamura T, Takei Y, Sato N. Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals. Hepatology 2001;34:288-97.
-
(2001)
Hepatology
, vol.34
, pp. 288-297
-
-
Ikejima, K.1
Honda, H.2
Yoshikawa, M.3
Hirose, M.4
Kitamura, T.5
Takei, Y.6
Sato, N.7
-
51
-
-
0036288668
-
Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver
-
Honda H, Ikejima K, Hirose M, Yoshikawa M, Lang T, Enomoto N, Kitamura T, Takei Y, Sato N. Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver. Hepatology 2002;36:12-21.
-
(2002)
Hepatology
, vol.36
, pp. 12-21
-
-
Honda, H.1
Ikejima, K.2
Hirose, M.3
Yoshikawa, M.4
Lang, T.5
Enomoto, N.6
Kitamura, T.7
Takei, Y.8
Sato, N.9
-
52
-
-
0036234147
-
Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat
-
Ikejima K, Takei Y, Honda H, Hirose M, Yoshikawa M, Zhang YJ, Lang T, Fukuda T, Yamashina S, Kitamura T, Sato N. Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat. Gastroenterology 2002;122:1399-410.
-
(2002)
Gastroenterology
, vol.122
, pp. 1399-1410
-
-
Ikejima, K.1
Takei, Y.2
Honda, H.3
Hirose, M.4
Yoshikawa, M.5
Zhang, Y.J.6
Lang, T.7
Fukuda, T.8
Yamashina, S.9
Kitamura, T.10
Sato, N.11
-
53
-
-
0036288818
-
Leptin, liver and obese mice - Fibrosis in the fat lane
-
Anania FA. Leptin, liver and obese mice - fibrosis in the fat lane. Hepatology 2002;36:246-8.
-
(2002)
Hepatology
, vol.36
, pp. 246-248
-
-
Anania, F.A.1
-
54
-
-
0029980285
-
cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1)
-
Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun 1996;221:286-9.
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 286-289
-
-
Maeda, K.1
Okubo, K.2
Shimomura, I.3
Funahashi, T.4
Matsuzawa, Y.5
Matsubara, K.6
-
55
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999;257:79-83.
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
Takahashi, M.4
Maeda, K.5
Miyagawa, J.6
Hotta, K.7
Shimomura, I.8
Nakamura, T.9
Miyaoka, K.10
Kuriyama, H.11
Nishida, M.12
Yamashita, S.13
Okubo, K.14
Matsubara, K.15
Muraguchi, M.16
Ohmoto, Y.17
Funahashi, T.18
Matsuzawa, Y.19
-
56
-
-
0034096988
-
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
-
Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, Okamoto Y, Iwahashi H, Kuriyama H, Ouchi N, Maeda K, Nishida M, Kihara S, Sakai N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000;20: 1595-9.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1595-1599
-
-
Hotta, K.1
Funahashi, T.2
Arita, Y.3
Takahashi, M.4
Matsuda, M.5
Okamoto, Y.6
Iwahashi, H.7
Kuriyama, H.8
Ouchi, N.9
Maeda, K.10
Nishida, M.11
Kihara, S.12
Sakai, N.13
Nakajima, T.14
Hasegawa, K.15
Muraguchi, M.16
Ohmoto, Y.17
Nakamura, T.18
Yamashita, S.19
Hanafusa, T.20
Matsuzawa, Y.21
more..
-
57
-
-
0242694056
-
Molecular mechanism of insulin resistance and obesity
-
Kadowaki T, Hara K, Yamauchi T, Terauchi Y, Tobe K, Nagai R. Molecular mechanism of insulin resistance and obesity. Exp Biol Med 2003;228:1111-7.
-
(2003)
Exp Biol Med
, vol.228
, pp. 1111-1117
-
-
Kadowaki, T.1
Hara, K.2
Yamauchi, T.3
Terauchi, Y.4
Tobe, K.5
Nagai, R.6
-
58
-
-
3042744039
-
Elevated circulating adiponectin levels in liver cirrhosis are associated with reduced liver function and altered hepatic hemodynamics
-
Tietge UJ, Boker KH, Manns MP, Bahr MJ. Elevated circulating adiponectin levels in liver cirrhosis are associated with reduced liver function and altered hepatic hemodynamics. Am J Physiol Endocrinol Metab 2004;287:E82-9.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Tietge, U.J.1
Boker, K.H.2
Manns, M.P.3
Bahr, M.J.4
-
59
-
-
1042276559
-
Adiponectin, hepatocellular dysfunction and insulin sensitivity
-
Lopez-Bermejo A, Botas P, Funahashi T, Delgado E, Kihara S, Ricart W, Fernandez-Real JM. Adiponectin, hepatocellular dysfunction and insulin sensitivity. Clin Endocrinol (Oxf) 2004;60:256-63.
-
(2004)
Clin Endocrinol (Oxf)
, vol.60
, pp. 256-263
-
-
Lopez-Bermejo, A.1
Botas, P.2
Funahashi, T.3
Delgado, E.4
Kihara, S.5
Ricart, W.6
Fernandez-Real, J.M.7
-
60
-
-
0034816307
-
Change in expression of GBP28/adiponectin in carbon tetrachloride- administrated mouse liver
-
Yoda-Murakami M, Taniguchi M, Takahashi K, Kawamata S, Saito K, Choi-Miura NH, Tomita M. Change in expression of GBP28/adiponectin in carbon tetrachloride-administrated mouse liver. Biochem Biophys Res Commun 2001;285:372-7.
-
(2001)
Biochem Biophys Res Commun
, vol.285
, pp. 372-377
-
-
Yoda-Murakami, M.1
Taniguchi, M.2
Takahashi, K.3
Kawamata, S.4
Saito, K.5
Choi-Miura, N.H.6
Tomita, M.7
-
61
-
-
10744228583
-
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
-
Kamada Y, Tamura S, Kiso S, Matsumoto H, Saji Y, Yoshida Y, Fukui K, Maeda N, Nishizawa H, Nagaretani H, Okamoto Y, Kihara S, Miyagawa JI, Shinomura Y, Funahashi T, Matsuzawa Y. Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology 2003;125:1796-807.
-
(2003)
Gastroenterology
, vol.125
, pp. 1796-1807
-
-
Kamada, Y.1
Tamura, S.2
Kiso, S.3
Matsumoto, H.4
Saji, Y.5
Yoshida, Y.6
Fukui, K.7
Maeda, N.8
Nishizawa, H.9
Nagaretani, H.10
Okamoto, Y.11
Kihara, S.12
Miyagawa, J.I.13
Shinomura, Y.14
Funahashi, T.15
Matsuzawa, Y.16
-
62
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003;112:91-100.
-
(2003)
J Clin Invest
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
63
-
-
0027245963
-
Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation
-
Smas CM, Sul HS. Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation. Cell 1993; 73:725-34.
-
(1993)
Cell
, vol.73
, pp. 725-734
-
-
Smas, C.M.1
Sul, H.S.2
-
64
-
-
0027467416
-
dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line
-
Laborda J, Sausville EA, Hoffman T, Notario V. dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line. J Biol Chem 1993;268:3817-20.
-
(1993)
J Biol Chem
, vol.268
, pp. 3817-3820
-
-
Laborda, J.1
Sausville, E.A.2
Hoffman, T.3
Notario, V.4
-
65
-
-
0034161309
-
A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells
-
Han W, Ye Q, Moore MA. A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells. Blood 2000;95:1616-25.
-
(2000)
Blood
, vol.95
, pp. 1616-1625
-
-
Han, W.1
Ye, Q.2
Moore, M.A.3
-
66
-
-
0033514948
-
Reversing adipocyte differentiation: Implications for treatment of obesity
-
Zhou YT, Wang ZW, Higa M, Newgard CB, Unger RH. Reversing adipocyte differentiation: implications for treatment of obesity. Proc Natl Acad Sci U S A 1999;96: 2391-5.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2391-2395
-
-
Zhou, Y.T.1
Wang, Z.W.2
Higa, M.3
Newgard, C.B.4
Unger, R.H.5
-
67
-
-
0036295999
-
Insights from gene arrays on the development and growth regulation of uterine leiomyomata
-
Tsibris JC, Segars J, Coppola D, Mane S, Wilbanks GD, O'Brien WF, Spellacy WN. Insights from gene arrays on the development and growth regulation of uterine leiomyomata. Fertil Steril 2002;78:114-21.
-
(2002)
Fertil Steril
, vol.78
, pp. 114-121
-
-
Tsibris, J.C.1
Segars, J.2
Coppola, D.3
Mane, S.4
Wilbanks, G.D.5
O'Brien, W.F.6
Spellacy, W.N.7
-
68
-
-
1142275114
-
The human Delta-like 1 homologue is implicated in the progression of liver fibrosis in biliary atresia
-
Huang CC, Chuang JH, Huang LL, Chou MH, Wu CL, Chen CM, Hsieh CS, Lee SY, Chen CL. The human Delta-like 1 homologue is implicated in the progression of liver fibrosis in biliary atresia. J Pathol 2004;202:172-9.
-
(2004)
J Pathol
, vol.202
, pp. 172-179
-
-
Huang, C.C.1
Chuang, J.H.2
Huang, L.L.3
Chou, M.H.4
Wu, C.L.5
Chen, C.M.6
Hsieh, C.S.7
Lee, S.Y.8
Chen, C.L.9
-
69
-
-
0035083958
-
Apoptosis of hepatic stellate cells: Involvement in resolution of biliary fibrosis and regulation by soluble growth factors
-
Issa R, Williams E, Trim N, Kendall T, Arthur MJ, Reichen J, Benyon RC, Iredale JP. Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors. Gut 2001;48: 548-57.
-
(2001)
Gut
, vol.48
, pp. 548-557
-
-
Issa, R.1
Williams, E.2
Trim, N.3
Kendall, T.4
Arthur, M.J.5
Reichen, J.6
Benyon, R.C.7
Iredale, J.P.8
-
70
-
-
0036936550
-
Roles for insulin-like growth factor I and transforming growth factor-beta in fibrotic lung disease
-
Krein PM, Winston BW. Roles for insulin-like growth factor I and transforming growth factor-beta in fibrotic lung disease. Chest 2002;122:289S-93S.
-
(2002)
Chest
, vol.122
-
-
Krein, P.M.1
Winston, B.W.2
-
71
-
-
0344099082
-
Protective effect of IGF-1 on experimental liver cirrhosis-induced common bile duct ligation
-
Canturk NZ, Canturk Z, Ozden M, Dalcik H, Yardimoglu M, Tulubas F. Protective effect of IGF-1 on experimental liver cirrhosis-induced common bile duct ligation. Hepatogastroenterology 2003;50:2061-6.
-
(2003)
Hepatogastroenterology
, vol.50
, pp. 2061-2066
-
-
Canturk, N.Z.1
Canturk, Z.2
Ozden, M.3
Dalcik, H.4
Yardimoglu, M.5
Tulubas, F.6
-
72
-
-
0038369150
-
Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women
-
Cappola AR, Xue QL, Ferrucci L, Guralnik JM, Volpato S, Fried LP. Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women. J Clin Endocrinol Metab 2003;88:2019-25.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 2019-2025
-
-
Cappola, A.R.1
Xue, Q.L.2
Ferrucci, L.3
Guralnik, J.M.4
Volpato, S.5
Fried, L.P.6
-
73
-
-
0043264091
-
C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups
-
Heald AH, Anderson SG, Ivison F, Laing I, Gibson JM, Cruickshank K. C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis 2003;170:79-86.
-
(2003)
Atherosclerosis
, vol.170
, pp. 79-86
-
-
Heald, A.H.1
Anderson, S.G.2
Ivison, F.3
Laing, I.4
Gibson, J.M.5
Cruickshank, K.6
-
74
-
-
0037470488
-
Evolutionary medicine: From dwarf model systems to healthy centenarians?
-
Longo VD, Finch CE. Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 2003; 299:1342-6.
-
(2003)
Science
, vol.299
, pp. 1342-1346
-
-
Longo, V.D.1
Finch, C.E.2
-
75
-
-
1642331710
-
Insulin treatment improves the systemic inflammatory reaction to severe trauma
-
Jeschke MG, Klein D, Herndon DN. Insulin treatment improves the systemic inflammatory reaction to severe trauma. Ann Surg 2004;239:553-60.
-
(2004)
Ann Surg
, vol.239
, pp. 553-560
-
-
Jeschke, M.G.1
Klein, D.2
Herndon, D.N.3
-
77
-
-
0033793133
-
Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
-
Chinetti G, Fruchart JC, Staels B. Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm Res 2000;49:497-505.
-
(2000)
Inflamm Res
, vol.49
, pp. 497-505
-
-
Chinetti, G.1
Fruchart, J.C.2
Staels, B.3
-
78
-
-
0035127894
-
Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury
-
Nakajima A, Wada K, Miki H, Kubota N, Nakajima N, Terauchi Y, Ohnishi S, Saubermann LJ, Kadowaki T, Blumberg RS, Nagai R, Matsuhashi N. Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury. Gastroenterology 2001;120:460-9.
-
(2001)
Gastroenterology
, vol.120
, pp. 460-469
-
-
Nakajima, A.1
Wada, K.2
Miki, H.3
Kubota, N.4
Nakajima, N.5
Terauchi, Y.6
Ohnishi, S.7
Saubermann, L.J.8
Kadowaki, T.9
Blumberg, R.S.10
Nagai, R.11
Matsuhashi, N.12
-
79
-
-
0035132330
-
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
-
Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 2001;7:48-52.
-
(2001)
Nat Med
, vol.7
, pp. 48-52
-
-
Chawla, A.1
Barak, Y.2
Nagy, L.3
Liao, D.4
Tontonoz, P.5
Evans, R.M.6
-
80
-
-
10744221756
-
Pioglitazone prevents alcohol-induced fatty liver in rats through up-regulation of c-Met
-
Tomita K, Azuma T, Kitamura N, Nishida J, Tamiya G, Oka A, Inokuchi S, Nishimura T, Suematsu M, Ishii H. Pioglitazone prevents alcohol-induced fatty liver in rats through up-regulation of c-Met. Gastroenterology 2004; 126:873-85.
-
(2004)
Gastroenterology
, vol.126
, pp. 873-885
-
-
Tomita, K.1
Azuma, T.2
Kitamura, N.3
Nishida, J.4
Tamiya, G.5
Oka, A.6
Inokuchi, S.7
Nishimura, T.8
Suematsu, M.9
Ishii, H.10
-
81
-
-
0032903634
-
Hepatocyte growth factor gene therapy of liver cirrhosis in rats
-
Ueki T, Kaneda Y, Tsutsui H, Nakanishi K, Sawa Y, Morishita R, Matsumoto K, Nakamura T, Takahashi H, Okamoto E, Fujimoto J. Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med 1999;5:226-30.
-
(1999)
Nat Med
, vol.5
, pp. 226-230
-
-
Ueki, T.1
Kaneda, Y.2
Tsutsui, H.3
Nakanishi, K.4
Sawa, Y.5
Morishita, R.6
Matsumoto, K.7
Nakamura, T.8
Takahashi, H.9
Okamoto, E.10
Fujimoto, J.11
-
82
-
-
0042377452
-
Hepatocyte growth factor gene transfer into the liver via the portal vein using electroporation attenuates rat liver cirrhosis
-
Matsuno Y, Iwata H, Umeda Y, Takagi H, Mori Y, Kosugi A, Matsumoto K, Nakamura T, Hirose H. Hepatocyte growth factor gene transfer into the liver via the portal vein using electroporation attenuates rat liver cirrhosis. Gene Ther 2003;10:1559-66.
-
(2003)
Gene Ther
, vol.10
, pp. 1559-1566
-
-
Matsuno, Y.1
Iwata, H.2
Umeda, Y.3
Takagi, H.4
Mori, Y.5
Kosugi, A.6
Matsumoto, K.7
Nakamura, T.8
Hirose, H.9
-
83
-
-
0042847330
-
Peroxisome proliferator-activated receptor alpha (PPARalpha) agonist treatment reverses PPARalpha dysfunction and abnormalities in hepatic lipid metabolism in ethanol-fed mice
-
Fischer M, You M, Matsumoto M, Crabb DW. Peroxisome proliferator- activated receptor alpha (PPARalpha) agonist treatment reverses PPARalpha dysfunction and abnormalities in hepatic lipid metabolism in ethanol-fed mice. J Biol Chem 2003;278:27997-8004.
-
(2003)
J Biol Chem
, vol.278
, pp. 27997-28004
-
-
Fischer, M.1
You, M.2
Matsumoto, M.3
Crabb, D.W.4
-
84
-
-
2342644813
-
Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice
-
Ip E, Farrell G, Hall P, Robertson G, Leclercq I. Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice. Hepatology 2004;39:1286-96.
-
(2004)
Hepatology
, vol.39
, pp. 1286-1296
-
-
Ip, E.1
Farrell, G.2
Hall, P.3
Robertson, G.4
Leclercq, I.5
-
85
-
-
0038644530
-
Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells
-
Saxena NK, Saliba G, Floyd JJ, Anania FA. Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells. J Cell Biochem 2003; 89:311-20.
-
(2003)
J Cell Biochem
, vol.89
, pp. 311-320
-
-
Saxena, N.K.1
Saliba, G.2
Floyd, J.J.3
Anania, F.A.4
-
86
-
-
0041327882
-
Leptin receptor-deficient Zucker (fa/fa) rat retards the development of pig serum-induced liver fibrosis with Kupffer cell dysfunction
-
Sakaida I, Jinhua S, Uchida K, Terai S, Okita K. Leptin receptor-deficient Zucker (fa/fa) rat retards the development of pig serum-induced liver fibrosis with Kupffer cell dysfunction. Life Sci 2003;73:2491-501.
-
(2003)
Life Sci
, vol.73
, pp. 2491-2501
-
-
Sakaida, I.1
Jinhua, S.2
Uchida, K.3
Terai, S.4
Okita, K.5
-
87
-
-
0035195887
-
Leptin regulation of the immune response and the immunodeficiency of malnutrition
-
Faggioni R, Feingold KR, Grunfeld C. Leptin regulation of the immune response and the immunodeficiency of malnutrition. FASEB J 2001;15:2565-71.
-
(2001)
FASEB J
, vol.15
, pp. 2565-2571
-
-
Faggioni, R.1
Feingold, K.R.2
Grunfeld, C.3
-
88
-
-
0029776030
-
The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
-
Baumann H, Morella KK, White DW, Dembski M, Bailon PS, Kim H, Lai CF, Tartaglia LA The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. Proc Natl Acad Sci U S A 1996;93: 8374-8.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 8374-8378
-
-
Baumann, H.1
Morella, K.K.2
White, D.W.3
Dembski, M.4
Bailon, P.S.5
Kim, H.6
Lai, C.F.7
Tartaglia, L.A.8
-
89
-
-
0037784230
-
Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases
-
Streetz KL, Tacke F, Leifeld L, Wustefeld T, Graw A, Klein C, Kamino K, Spengler U, Kreipe H, Kubicka S, Muller W, Manns MP, Trautwein C. Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases. Hepatology 2003;38:218-29.
-
(2003)
Hepatology
, vol.38
, pp. 218-229
-
-
Streetz, K.L.1
Tacke, F.2
Leifeld, L.3
Wustefeld, T.4
Graw, A.5
Klein, C.6
Kamino, K.7
Spengler, U.8
Kreipe, H.9
Kubicka, S.10
Muller, W.11
Manns, M.P.12
Trautwein, C.13
-
90
-
-
0033970969
-
Increased toxin-induced liver injury and fibrosis in interleukin-6- deficient mice
-
Kovalovich K, DeAngelis RA, Li W, Furth EE, Ciliberto G, Taub R. Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice. Hepatology 2000;31: 149-59.
-
(2000)
Hepatology
, vol.31
, pp. 149-159
-
-
Kovalovich, K.1
DeAngelis, R.A.2
Li, W.3
Furth, E.E.4
Ciliberto, G.5
Taub, R.6
-
91
-
-
0033838920
-
The development and compensation of biliary cirrhosis in interleukin-6-deficient mice
-
Ezure T, Sakamoto T, Tsuji H, Lunz JG 3rd, Murase N, Fung JJ, Demetris AJ. The development and compensation of biliary cirrhosis in interleukin-6-deficient mice. Am J Pathol 2000;156:1627-39.
-
(2000)
Am J Pathol
, vol.156
, pp. 1627-1639
-
-
Ezure, T.1
Sakamoto, T.2
Tsuji, H.3
Lunz III, J.G.4
Murase, N.5
Fung, J.J.6
Demetris, A.J.7
-
92
-
-
0032831637
-
Attenuated liver fibrosis and depressed serum albumin levels in carbon tetrachloride-treated IL-6-deficient mice
-
Natsume M, Tsuji H, Harada A, Akiyama M, Yano T, Ishikura H, Nakanishi I, Matsushima K, Kaneko S, Mukaida N. Attenuated liver fibrosis and depressed serum albumin levels in carbon tetrachloride-treated IL-6-deficient mice. J Leukoc Biol 1999;66:601-8.
-
(1999)
J Leukoc Biol
, vol.66
, pp. 601-608
-
-
Natsume, M.1
Tsuji, H.2
Harada, A.3
Akiyama, M.4
Yano, T.5
Ishikura, H.6
Nakanishi, I.7
Matsushima, K.8
Kaneko, S.9
Mukaida, N.10
-
93
-
-
0037129861
-
Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell
-
Arita Y, Kihara S, Ouchi N, Maeda K, Kuriyama H, Okamoto Y, Kumada M, Hotta K, Nishida M, Takahashi M, Nakamura T, Shimomura I, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y. Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation 2002;105:2893-8.
-
(2002)
Circulation
, vol.105
, pp. 2893-2898
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
Maeda, K.4
Kuriyama, H.5
Okamoto, Y.6
Kumada, M.7
Hotta, K.8
Nishida, M.9
Takahashi, M.10
Nakamura, T.11
Shimomura, I.12
Muraguchi, M.13
Ohmoto, Y.14
Funahashi, T.15
Matsuzawa, Y.16
-
94
-
-
0024840085
-
Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells
-
Pinzani M, Gesualdo L, Sabbah GM, Abboud HE. Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells. J Clin Invest 1989;84:1786-93.
-
(1989)
J Clin Invest
, vol.84
, pp. 1786-1793
-
-
Pinzani, M.1
Gesualdo, L.2
Sabbah, G.M.3
Abboud, H.E.4
-
95
-
-
0037459090
-
Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes
-
Fasshauer M, Kralisch S, Klier M, Lossner U, Bluher M, Klein J, Paschke R. Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes. Biochem Biophys Res Commun 2003;301: 1045-50.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 1045-1050
-
-
Fasshauer, M.1
Kralisch, S.2
Klier, M.3
Lossner, U.4
Bluher, M.5
Klein, J.6
Paschke, R.7
-
96
-
-
2442464884
-
Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages
-
Kumada M, Kihara S, Ouchi N, Kobayashi H, Okamoto Y, Ohashi K, Maeda K, Nagaretani H, Kishida K, Maeda N, Nagasawa A, Funahashi T, Matsuzawa Y. Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages. Circulation 2004;109:2046-9.
-
(2004)
Circulation
, vol.109
, pp. 2046-2049
-
-
Kumada, M.1
Kihara, S.2
Ouchi, N.3
Kobayashi, H.4
Okamoto, Y.5
Ohashi, K.6
Maeda, K.7
Nagaretani, H.8
Kishida, K.9
Maeda, N.10
Nagasawa, A.11
Funahashi, T.12
Matsuzawa, Y.13
-
97
-
-
0347986520
-
Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARalpha, PPARgamma, and LXR
-
Chinetti G, Zawadski C, Fruchart JC, Staels B. Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARalpha, PPARgamma, and LXR. Biochem Biophys Res Commun 2004;314:151-8.
-
(2004)
Biochem Biophys Res Commun
, vol.314
, pp. 151-158
-
-
Chinetti, G.1
Zawadski, C.2
Fruchart, J.C.3
Staels, B.4
-
98
-
-
4143119937
-
Leptin treatment markedly increased plasma adiponectin, but barely decreased plasma resistin of ob/ob mice
-
Delporte ML, Ait El Mkadem S, Quisquater M, Brichard SM. Leptin treatment markedly increased plasma adiponectin, but barely decreased plasma resistin of ob/ob mice. Am J Physiol Endocrinol Metab 2004;287:E446-53.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Delporte, M.L.1
Ait El Mkadem, S.2
Quisquater, M.3
Brichard, S.M.4
-
99
-
-
0029026661
-
Cytokines and cellular crosstalk involved in the activation of fat-storing cells
-
Gressner AM. Cytokines and cellular crosstalk involved in the activation of fat-storing cells. J Hepatol 1995; 22:28-36.
-
(1995)
J Hepatol
, vol.22
, pp. 28-36
-
-
Gressner, A.M.1
-
100
-
-
0037221910
-
Liver fibrosis: Insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors
-
Yang C, Zeisberg M, Mosterman B, Sudhakar A, Yerramalla U, Holthaus K, Xu L, Eng F, Afdhal N, Kalluri R. Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors. Gastroenterology 2003;124:147-59.
-
(2003)
Gastroenterology
, vol.124
, pp. 147-159
-
-
Yang, C.1
Zeisberg, M.2
Mosterman, B.3
Sudhakar, A.4
Yerramalla, U.5
Holthaus, K.6
Xu, L.7
Eng, F.8
Afdhal, N.9
Kalluri, R.10
-
101
-
-
0342369599
-
Expression of epidermal growth factor and its receptor in cirrhotic liver disease
-
Komuves LG, Feren A, Jones AL, Fodor E. Expression of epidermal growth factor and its receptor in cirrhotic liver disease. J Histochem Cytochem 2000;48:821-30.
-
(2000)
J Histochem Cytochem
, vol.48
, pp. 821-830
-
-
Komuves, L.G.1
Feren, A.2
Jones, A.L.3
Fodor, E.4
-
102
-
-
1642398160
-
Transit-amplifying ductular (oval) cells and their hepatocytic progeny are characterized by a novel and distinctive expression of delta-like protein/preadipocyte factor 1/fetal antigen 1
-
Jensen CH, Jauho EI, Santoni-Rugiu E, Holmskov U, Teisner B, Tygstrup N, Bisgaard HC. Transit-amplifying ductular (oval) cells and their hepatocytic progeny are characterized by a novel and distinctive expression of delta-like protein/preadipocyte factor 1/fetal antigen 1. Am J Pathol 2004;164:1347-59.
-
(2004)
Am J Pathol
, vol.164
, pp. 1347-1359
-
-
Jensen, C.H.1
Jauho, E.I.2
Santoni-Rugiu, E.3
Holmskov, U.4
Teisner, B.5
Tygstrup, N.6
Bisgaard, H.C.7
-
103
-
-
0036631089
-
Expression of preadipocyte factor-1(Pref-1), a delta-like protein, in healing mouse ears
-
Samulewicz SJ, Seitz A, Clark L, Heber-Katz E. Expression of preadipocyte factor-1(Pref-1), a delta-like protein, in healing mouse ears. Wound Repair Regen 2002;10:215-21.
-
(2002)
Wound Repair Regen
, vol.10
, pp. 215-221
-
-
Samulewicz, S.J.1
Seitz, A.2
Clark, L.3
Heber-Katz, E.4
-
104
-
-
0842305691
-
The escalating pandemics of obesity and sedentary lifestyle. A call to action for clinicians
-
Manson JE, Skerrett PJ, Greenland P, Vanltallie TB. The escalating pandemics of obesity and sedentary lifestyle. A call to action for clinicians. Arch Intern Med 2004; 164:249-58.
-
(2004)
Arch Intern Med
, vol.164
, pp. 249-258
-
-
Manson, J.E.1
Skerrett, P.J.2
Greenland, P.3
Vanltallie, T.B.4
-
105
-
-
0346266078
-
Weight-for-height reference and the prevalence of obesity for school children and adolescents in Taiwan and Fuchien Areas
-
Huang YC, Wu JY, Yang MJ. Weight-for-height reference and the prevalence of obesity for school children and adolescents in Taiwan and Fuchien Areas. J Chin Med Assoc 2003;66:599-606.
-
(2003)
J Chin Med Assoc
, vol.66
, pp. 599-606
-
-
Huang, Y.C.1
Wu, J.Y.2
Yang, M.J.3
-
106
-
-
1342268112
-
Overweight in childhood and adolescence
-
Dietz WH. Overweight in childhood and adolescence. N Engl J Med 2004;350:855-7.
-
(2004)
N Engl J Med
, vol.350
, pp. 855-857
-
-
Dietz, W.H.1
-
107
-
-
1542285988
-
Surgery for severe obesity
-
Steinbrook R. Surgery for severe obesity. N Engl J Med 2004;350:1075-9.
-
(2004)
N Engl J Med
, vol.350
, pp. 1075-1079
-
-
Steinbrook, R.1
-
108
-
-
0033329864
-
Liver pathology and the metabolic syndrome X in severe obesity
-
Marceau P, Biron S, Hould FS, Marceau S, Simard S, Thung SN, Kral JG. Liver pathology and the metabolic syndrome X in severe obesity. J Clin Endocrinol Metab 1999;84:1513-7.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 1513-1517
-
-
Marceau, P.1
Biron, S.2
Hould, F.S.3
Marceau, S.4
Simard, S.5
Thung, S.N.6
Kral, J.G.7
-
109
-
-
0348047323
-
Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis
-
Krai JG, Thung SN, Biron S, Hould FS, Lebel S, Marceau S, Simard S, Marceau P. Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis. Surgery 2004;135:48-58.
-
(2004)
Surgery
, vol.135
, pp. 48-58
-
-
Krai, J.G.1
Thung, S.N.2
Biron, S.3
Hould, F.S.4
Lebel, S.5
Marceau, S.6
Simard, S.7
Marceau, P.8
-
110
-
-
0141594639
-
Is obesity a risk factor for cirrhosis-related death or hospitalization? A population-based cohort study
-
Ioannou GN, Weiss NS, Kowdley KV, Dominitz JA. Is obesity a risk factor for cirrhosis-related death or hospitalization? A population-based cohort study. Gastroenterology 2003;125:1053-9.
-
(2003)
Gastroenterology
, vol.125
, pp. 1053-1059
-
-
Ioannou, G.N.1
Weiss, N.S.2
Kowdley, K.V.3
Dominitz, J.A.4
-
111
-
-
0034096988
-
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
-
Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, Okamoto Y, Iwahashi H, Kuriyama H, Ouchi N, Maeda K, Nishida M, Kihara S, Sakai N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000;20:1595-9.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1595-1599
-
-
Hotta, K.1
Funahashi, T.2
Arita, Y.3
Takahashi, M.4
Matsuda, M.5
Okamoto, Y.6
Iwahashi, H.7
Kuriyama, H.8
Ouchi, N.9
Maeda, K.10
Nishida, M.11
Kihara, S.12
Sakai, N.13
Nakajima, T.14
Hasegawa, K.15
Muraguchi, M.16
Ohmoto, Y.17
Nakamura, T.18
Yamashita, S.19
Hanafusa, T.20
Matsuzawa, Y.21
more..
-
112
-
-
0034891684
-
Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin
-
Yang WS, Lee WJ, Funahashi T, Tanaka S, Matsuzawa Y, Chao CL, Chen CL, Tai TY, Chuang LM. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab 2001;86:3815-9.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 3815-3819
-
-
Yang, W.S.1
Lee, W.J.2
Funahashi, T.3
Tanaka, S.4
Matsuzawa, Y.5
Chao, C.L.6
Chen, C.L.7
Tai, T.Y.8
Chuang, L.M.9
-
113
-
-
0037840403
-
Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: A randomized trial
-
Esposito K, Pontillo A, Di Palo C, Giugliano G, Masella M, Marfella R, Giugliano D. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. JAMA 2003;289: 1799-804.
-
(2003)
JAMA
, vol.289
, pp. 1799-1804
-
-
Esposito, K.1
Pontillo, A.2
Di Palo, C.3
Giugliano, G.4
Masella, M.5
Marfella, R.6
Giugliano, D.7
-
114
-
-
1642298199
-
Effect of liposuction on insulin resistance and vascular inflammatory markers in obese women
-
Giugliano G, Nicoletti G, Grella E, Giugliano F, Esposito K, Scuderi N, D'Andrea F. Effect of liposuction on insulin resistance and vascular inflammatory markers in obese women. Br J Plast Surg 2004;57:190-4.
-
(2004)
Br J Plast Surg
, vol.57
, pp. 190-194
-
-
Giugliano, G.1
Nicoletti, G.2
Grella, E.3
Giugliano, F.4
Esposito, K.5
Scuderi, N.6
D'Andrea, F.7
-
115
-
-
1942440850
-
Leptin and the proinflammatory state associated with human obesity
-
Hukshorn CJ, Lindeman JH, Toet KH, Saris WH, Eilers PH, Westerterp-Plantenga MS, Kooistra T. Leptin and the proinflammatory state associated with human obesity. J Clin Endocrinol Metab 2004;89:1773-8.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1773-1778
-
-
Hukshorn, C.J.1
Lindeman, J.H.2
Toet, K.H.3
Saris, W.H.4
Eilers, P.H.5
Westerterp-Plantenga, M.S.6
Kooistra, T.7
-
116
-
-
0842300373
-
Steatosis and hepatitis C virus: Mechanisms and significance for hepatic and extrahepatic disease
-
Lonardo A, Adinolfi LE, Loria P, Carulli N, Ruggiero G, Day CP. Steatosis and hepatitis C virus: mechanisms and significance for hepatic and extrahepatic disease. Gastroenterology 2004;126:586-97.
-
(2004)
Gastroenterology
, vol.126
, pp. 586-597
-
-
Lonardo, A.1
Adinolfi, L.E.2
Loria, P.3
Carulli, N.4
Ruggiero, G.5
Day, C.P.6
-
118
-
-
4344701247
-
The multi-dimensional regulation of gene expression by fatty acids: Polyunsaturated fats as nutrient sensors
-
Clarke SD. The multi-dimensional regulation of gene expression by fatty acids: polyunsaturated fats as nutrient sensors. Curr Opin Lipidol 2004;15:13-8.
-
(2004)
Curr Opin Lipidol
, vol.15
, pp. 13-18
-
-
Clarke, S.D.1
-
119
-
-
4043077961
-
Molecular mediators of hepatic steatosis and liver injury
-
Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 2004;114:147-52.
-
(2004)
J Clin Invest
, vol.114
, pp. 147-152
-
-
Browning, J.D.1
Horton, J.D.2
-
120
-
-
0034071520
-
Diabetes mellitus as a risk factor of liver cirrhosis in patients with chronic hepatitis B virus infection
-
Huo TI, Wu JC, Lee PC, Tsay SH, Chang FY, Lee SD. Diabetes mellitus as a risk factor of liver cirrhosis in patients with chronic hepatitis B virus infection. J Clin Gastroenterol 2000;30:250-4.
-
(2000)
J Clin Gastroenterol
, vol.30
, pp. 250-254
-
-
Huo, T.I.1
Wu, J.C.2
Lee, P.C.3
Tsay, S.H.4
Chang, F.Y.5
Lee, S.D.6
|