-
1
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn B.B., Flier J.S. Obesity and insulin resistance. J. Clin. Invest. 106:2000;473-481.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
2
-
-
0013461697
-
Interleukin-6 (IL-6) reduces gene and protein expression of IRS-1 and GLUT4 and is overexpressed in human fat cells from insulin-resistant subjects
-
Rotter V., Nagaev I., Smith U. Interleukin-6 (IL-6) reduces gene and protein expression of IRS-1 and GLUT4 and is overexpressed in human fat cells from insulin-resistant subjects. Diabetes (Suppl. 2). 51:2002;A303.
-
(2002)
Diabetes (Suppl. 2)
, vol.51
, pp. 303
-
-
Rotter, V.1
Nagaev, I.2
Smith, U.3
-
3
-
-
0036894360
-
Interleukin-6 induces cellular insulin resistance in hepatocytes
-
Senn J.J., Klover P.J., Nowak I., Mooney R.A. Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes. 51:2002;3391-3399.
-
(2002)
Diabetes
, vol.51
, pp. 3391-3399
-
-
Senn, J.J.1
Klover, P.J.2
Nowak, I.3
Mooney, R.A.4
-
4
-
-
0028674174
-
Endocrine and carbohydrate responses to interleukin-6 in vivo
-
Stith R.D., Luo J. Endocrine and carbohydrate responses to interleukin-6 in vivo. Circ. Shock. 44:1994;210-215.
-
(1994)
Circ. Shock
, vol.44
, pp. 210-215
-
-
Stith, R.D.1
Luo, J.2
-
5
-
-
0032587240
-
The role of TNFalpha and TNF receptors in obesity and insulin resistance
-
Hotamisligil G.S. The role of TNFalpha and TNF receptors in obesity and insulin resistance. J. Intern. Med. 245:1999;621-625.
-
(1999)
J. Intern. Med.
, vol.245
, pp. 621-625
-
-
Hotamisligil, G.S.1
-
6
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
Steppan C.M., Bailey S.T., Bhat S., Brown E.J., Banerjee R.R., Wright C.M., Patel H.R., Ahima R.S., Lazar M.A. The hormone resistin links obesity to diabetes. Nature. 409:2001;307-312.
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
Steppan, C.M.1
Bailey, S.T.2
Bhat, S.3
Brown, E.J.4
Banerjee, R.R.5
Wright, C.M.6
Patel, H.R.7
Ahima, R.S.8
Lazar, M.A.9
-
7
-
-
0030735542
-
Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo
-
Mohamed-Ali V., Goodrick S., Rawesh A., Katz D.R., Miles J.M., Yudkin J.S., Klein S., Coppack S.W. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo. J. Clin. Endocrinol. Metab. 82:1997;4196-4200.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 4196-4200
-
-
Mohamed-Ali, V.1
Goodrick, S.2
Rawesh, A.3
Katz, D.R.4
Miles, J.M.5
Yudkin, J.S.6
Klein, S.7
Coppack, S.W.8
-
8
-
-
0030731621
-
NIDDM as a disease of the innate immune system: Association of acute-phase reactants and interleukin-6 with metabolic syndrome X
-
Pickup J.C., Mattock M.B., Chusney G.D., Burt D. NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X. Diabetologia. 40:1997;1286-1292.
-
(1997)
Diabetologia
, vol.40
, pp. 1286-1292
-
-
Pickup, J.C.1
Mattock, M.B.2
Chusney, G.D.3
Burt, D.4
-
9
-
-
0035403205
-
Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion
-
Vozarova B., Weyer C., Hanson K., Tataranni P.A., Bogardus C., Pratley R.E. Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion. Obes. Res. 9:2001;414-417.
-
(2001)
Obes. Res.
, vol.9
, pp. 414-417
-
-
Vozarova, B.1
Weyer, C.2
Hanson, K.3
Tataranni, P.A.4
Bogardus, C.5
Pratley, R.E.6
-
10
-
-
0035908632
-
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
-
Pradhan A.D., Manson J.E., Rifai N., Buring J.E., Ridker P.M. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA. 286:2001;327-334.
-
(2001)
JAMA
, vol.286
, pp. 327-334
-
-
Pradhan, A.D.1
Manson, J.E.2
Rifai, N.3
Buring, J.E.4
Ridker, P.M.5
-
11
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., Mori Y., Ide T., Murakami K., Tsuboyama-Kasaoka N., Ezaki O., Akanuma Y., Gavrilova O., Vinson C., Reitman M.L., Kagechika H., Shudo K., Yoda M., Nakano Y., Tobe K., Nagai R., Kimura S., Tomita M., Froguel P., Kadowaki T. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7:2001;941-946.
-
(2001)
Nat. Med.
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Terauchi, Y.4
Kubota, N.5
Hara, K.6
Mori, Y.7
Ide, T.8
Murakami, K.9
Tsuboyama-Kasaoka, N.10
Ezaki, O.11
Akanuma, Y.12
Gavrilova, O.13
Vinson, C.14
Reitman, M.L.15
Kagechika, H.16
Shudo, K.17
Yoda, M.18
Nakano, Y.19
Tobe, K.20
Nagai, R.21
Kimura, S.22
Tomita, M.23
Froguel, P.24
Kadowaki, T.25
more..
-
12
-
-
0034881391
-
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
-
Berg A.H., Combs T.P., Du X., Brownlee M., Scherer P.E. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat. Med. 7:2001;947-953.
-
(2001)
Nat. Med.
, vol.7
, pp. 947-953
-
-
Berg, A.H.1
Combs, T.P.2
Du, X.3
Brownlee, M.4
Scherer, P.E.5
-
13
-
-
0035852760
-
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
-
Fruebis J., Tsao T.S., Javorschi S., Ebbets-Reed D., Erickson M.R., Yen F.T., Bihain B.E., Lodish H.F. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc. Natl. Acad. Sci. USA. 98:2001;2005-2010.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2005-2010
-
-
Fruebis, J.1
Tsao, T.S.2
Javorschi, S.3
Ebbets-Reed, D.4
Erickson, M.R.5
Yen, F.T.6
Bihain, B.E.7
Lodish, H.F.8
-
14
-
-
0029980285
-
CDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1)
-
Maeda K., Okubo K., Shimomura I., Funahashi T., Matsuzawa Y., Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem. Biophys. Res. Commun. 221:1996;286-289.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.221
, pp. 286-289
-
-
Maeda, K.1
Okubo, K.2
Shimomura, I.3
Funahashi, T.4
Matsuzawa, Y.5
Matsubara, K.6
-
15
-
-
0028787490
-
A novel serum protein similar to C1q, produced exclusively in adipocytes
-
Scherer P.E., Williams S., Fogliano M., Baldini G., Lodish H.F. A novel serum protein similar to C1q, produced exclusively in adipocytes. J. Biol. Chem. 270:1995;26746-26749.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26746-26749
-
-
Scherer, P.E.1
Williams, S.2
Fogliano, M.3
Baldini, G.4
Lodish, H.F.5
-
16
-
-
17544382289
-
AdipoQ is a novel adipose-specific gene dysregulated in obesity
-
Hu E., Liang P., Spiegelman B.M. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J. Biol. Chem. 271:1996;10697-10703.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10697-10703
-
-
Hu, E.1
Liang, P.2
Spiegelman, B.M.3
-
17
-
-
0029836585
-
Isolation and characterization of GBP28, a novel gelatin-binding protein
-
Nakano Y., Tobe T., Choi-Miura N.H., Mazda T., Tomita M. Isolation and characterization of GBP28, a novel gelatin-binding protein. J. Biochem. (Tokyo). 120:1996;803-812.
-
(1996)
J. Biochem. (Tokyo)
, vol.120
, pp. 803-812
-
-
Nakano, Y.1
Tobe, T.2
Choi-Miura, N.H.3
Mazda, T.4
Tomita, M.5
-
18
-
-
0037135523
-
Disruption of adiponectin causes insulin resistance and neointimal formation
-
Kubota N., Terauchi Y., Yamauchi T., Kubota T., Moroi M., Matsui J., Eto K., Yamashita T., Kamon J., Satoh H., Yano W., Froguel P., Nagai R., Kimura S., Kadowaki T., Noda T. Disruption of adiponectin causes insulin resistance and neointimal formation. J. Biol. Chem. 277:2002;25863-25866.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25863-25866
-
-
Kubota, N.1
Terauchi, Y.2
Yamauchi, T.3
Kubota, T.4
Moroi, M.5
Matsui, J.6
Eto, K.7
Yamashita, T.8
Kamon, J.9
Satoh, H.10
Yano, W.11
Froguel, P.12
Nagai, R.13
Kimura, S.14
Kadowaki, T.15
Noda, T.16
-
19
-
-
0036063777
-
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
-
Maeda N., Shimomura I., Kishida K., Nishizawa H., Matsuda M., Nagaretani H., Furuyama N., Kondo H., Takahashi M., Arita Y., Komuro R., Ouchi N., Kihara S., Tochino Y., Okutomi K., Horie M., Takeda S., Aoyama T., Funahashi T., Matsuzawa Y. Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat. Med. 8:2002;731-737.
-
(2002)
Nat. Med.
, vol.8
, pp. 731-737
-
-
Maeda, N.1
Shimomura, I.2
Kishida, K.3
Nishizawa, H.4
Matsuda, M.5
Nagaretani, H.6
Furuyama, N.7
Kondo, H.8
Takahashi, M.9
Arita, Y.10
Komuro, R.11
Ouchi, N.12
Kihara, S.13
Tochino, Y.14
Okutomi, K.15
Horie, M.16
Takeda, S.17
Aoyama, T.18
Funahashi, T.19
Matsuzawa, Y.20
more..
-
20
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T., Kamon J., Minokoshi Y., Ito Y., Waki H., Uchida S., Yamashita S., Noda M., Kita S., Ueki K., Eto K., Akanuma Y., Froguel P., Foufelle F., Ferre P., Carling D., Kimura S., Nagai R., Kahn B.B., Kadowaki T. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat. Med. 8:2002;1288-1295.
-
(2002)
Nat. Med.
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
Yamashita, S.7
Noda, M.8
Kita, S.9
Ueki, K.10
Eto, K.11
Akanuma, Y.12
Froguel, P.13
Foufelle, F.14
Ferre, P.15
Carling, D.16
Kimura, S.17
Nagai, R.18
Kahn, B.B.19
Kadowaki, T.20
more..
-
21
-
-
0003306922
-
Globular adiponectin protected ob/ob mice from diabetes and apoE deficient mice from atherosclerosis
-
Yamauchi T., Kamon J., Waki H., Imai Y., Shimozawa N., Hioki K., Uchida S., Ito Y., Matsui J., Eto K., Komeda K., Tsunoda M., Murakami K., Ohnishi Y., Yamamura K., Ueyama Y., Froguel P., Kimura S., Nagai R., Kadowaki T. Globular adiponectin protected ob/ob mice from diabetes and apoE deficient mice from atherosclerosis. J. Biol. Chem. 2002.
-
(2002)
J. Biol. Chem.
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Imai, Y.4
Shimozawa, N.5
Hioki, K.6
Uchida, S.7
Ito, Y.8
Matsui, J.9
Eto, K.10
Komeda, K.11
Tsunoda, M.12
Murakami, K.13
Ohnishi, Y.14
Yamamura, K.15
Ueyama, Y.16
Froguel, P.17
Kimura, S.18
Nagai, R.19
Kadowaki, T.20
more..
-
22
-
-
0037180472
-
Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice
-
Okamoto Y., Kihara S., Ouchi N., Nishida M., Arita Y., Kumada M., Ohashi K., Sakai N., Shimomura I., Kobayashi H., Terasaka N., Inaba T., Funahashi T., Matsuzawa Y. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation. 106:2002;2767-2770.
-
(2002)
Circulation
, vol.106
, pp. 2767-2770
-
-
Okamoto, Y.1
Kihara, S.2
Ouchi, N.3
Nishida, M.4
Arita, Y.5
Kumada, M.6
Ohashi, K.7
Sakai, N.8
Shimomura, I.9
Kobayashi, H.10
Terasaka, N.11
Inaba, T.12
Funahashi, T.13
Matsuzawa, Y.14
-
23
-
-
0034999667
-
Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
-
Weyer C., Funahashi T., Tanaka S., Hotta K., Matsuzawa Y., Pratley R.E., Tataranni P.A. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J. Clin. Endocrinol. Metab. 86:2001;1930-1935.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1930-1935
-
-
Weyer, C.1
Funahashi, T.2
Tanaka, S.3
Hotta, K.4
Matsuzawa, Y.5
Pratley, R.E.6
Tataranni, P.A.7
-
24
-
-
0034096988
-
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
-
Hotta K., Funahashi T., Arita Y., Takahashi M., Matsuda M., Okamoto Y., Iwahashi H., Kuriyama H., Ouchi N., Maeda K., Nishida M., Kihara S., Sakai N., Nakajima T., Hasegawa K., Muraguchi M., Ohmoto Y., Nakamura T., Yamashita S., Hanafusa T., Matsuzawa Y. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler. Thromb. Vasc. Biol. 20:2000;1595-1599.
-
(2000)
Arterioscler. Thromb. Vasc. Biol.
, vol.20
, pp. 1595-1599
-
-
Hotta, K.1
Funahashi, T.2
Arita, Y.3
Takahashi, M.4
Matsuda, M.5
Okamoto, Y.6
Iwahashi, H.7
Kuriyama, H.8
Ouchi, N.9
Maeda, K.10
Nishida, M.11
Kihara, S.12
Sakai, N.13
Nakajima, T.14
Hasegawa, K.15
Muraguchi, M.16
Ohmoto, Y.17
Nakamura, T.18
Yamashita, S.19
Hanafusa, T.20
Matsuzawa, Y.21
more..
-
25
-
-
0035955453
-
Adiponectin gene expression is inhibited by β-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes
-
Fasshauer M., Klein J., Neumann S., Eszlinger M., Paschke R. Adiponectin gene expression is inhibited by β-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes. FEBS Lett. 507:2001;142-146.
-
(2001)
FEBS Lett.
, vol.507
, pp. 142-146
-
-
Fasshauer, M.1
Klein, J.2
Neumann, S.3
Eszlinger, M.4
Paschke, R.5
-
26
-
-
0036290813
-
Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes
-
Fasshauer M., Klein J., Neumann S., Eszlinger M., Paschke R. Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 290:2002;1084-1089.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 1084-1089
-
-
Fasshauer, M.1
Klein, J.2
Neumann, S.3
Eszlinger, M.4
Paschke, R.5
-
27
-
-
0034471789
-
Influences of ionomycin, dibutyryl-cycloAMP and tumour necrosis factor-α on intracellular amount and secretion of apM1 in differentiating primary human preadipocytes
-
Kappes A., Loffler G. Influences of ionomycin, dibutyryl-cycloAMP and tumour necrosis factor-α on intracellular amount and secretion of apM1 in differentiating primary human preadipocytes. Horm. Metab. Res. 32:2000;548-554.
-
(2000)
Horm. Metab. Res.
, vol.32
, pp. 548-554
-
-
Kappes, A.1
Loffler, G.2
-
28
-
-
0035462629
-
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein
-
Maeda N., Takahashi M., Funahashi T., Kihara S., Nishizawa H., Kishida K., Nagaretani H., Matsuda M., Komuro R., Ouchi N., Kuriyama H., Hotta K., Nakamura T., Shimomura I., Matsuzawa Y. PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes. 50:2001;2094-2099.
-
(2001)
Diabetes
, vol.50
, pp. 2094-2099
-
-
Maeda, N.1
Takahashi, M.2
Funahashi, T.3
Kihara, S.4
Nishizawa, H.5
Kishida, K.6
Nagaretani, H.7
Matsuda, M.8
Komuro, R.9
Ouchi, N.10
Kuriyama, H.11
Hotta, K.12
Nakamura, T.13
Shimomura, I.14
Matsuzawa, Y.15
-
29
-
-
0035900614
-
Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue
-
Halleux C.M., Takahashi M., Delporte M.L., Detry R., Funahashi T., Matsuzawa Y., Brichard S.M. Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue. Biochem. Biophys. Res. Commun. 288:2001;1102-1107.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.288
, pp. 1102-1107
-
-
Halleux, C.M.1
Takahashi, M.2
Delporte, M.L.3
Detry, R.4
Funahashi, T.5
Matsuzawa, Y.6
Brichard, S.M.7
-
30
-
-
0035968099
-
Isoproterenol inhibits resistin gene expression through a G(S)-protein-coupled pathway in 3T3-L1 adipocytes
-
Fasshauer M., Klein J., Neumann S., Eszlinger M., Paschke R. Isoproterenol inhibits resistin gene expression through a G(S)-protein-coupled pathway in 3T3-L1 adipocytes. FEBS Lett. 500:2001;60-63.
-
(2001)
FEBS Lett.
, vol.500
, pp. 60-63
-
-
Fasshauer, M.1
Klein, J.2
Neumann, S.3
Eszlinger, M.4
Paschke, R.5
-
31
-
-
0035834574
-
Tumor necrosis factor α is a negative regulator of resistin gene expression and secretion in 3T3-L1 adipocytes
-
Fasshauer M., Klein J., Neumann S., Eszlinger M., Paschke R. Tumor necrosis factor α is a negative regulator of resistin gene expression and secretion in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 288:2001;1027-1031.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.288
, pp. 1027-1031
-
-
Fasshauer, M.1
Klein, J.2
Neumann, S.3
Eszlinger, M.4
Paschke, R.5
-
32
-
-
0030782520
-
Dose-dependent effects of recombinant human interleukin-6 on glucose regulation
-
Tsigos C., Papanicolaou D.A., Kyrou I., Defensor R., Mitsiadis C.S., Chrousos G.P. Dose-dependent effects of recombinant human interleukin-6 on glucose regulation. J. Clin. Endocrinol. Metab. 82:1997;4167-4170.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 4167-4170
-
-
Tsigos, C.1
Papanicolaou, D.A.2
Kyrou, I.3
Defensor, R.4
Mitsiadis, C.S.5
Chrousos, G.P.6
-
33
-
-
0031762908
-
Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid
-
Fried S.K., Bunkin D.A., Greenberg A.S. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J. Clin. Endocrinol. Metab. 83:1998;847-850.
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 847-850
-
-
Fried, S.K.1
Bunkin, D.A.2
Greenberg, A.S.3
-
34
-
-
0027199126
-
IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase
-
Murakami M., Hibi M., Nakagawa N., Nakagawa T., Yasukawa K., Yamanishi K., Taga T., Kishimoto T. IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase. Science. 260:1993;1808-1810.
-
(1993)
Science
, vol.260
, pp. 1808-1810
-
-
Murakami, M.1
Hibi, M.2
Nakagawa, N.3
Nakagawa, T.4
Yasukawa, K.5
Yamanishi, K.6
Taga, T.7
Kishimoto, T.8
-
35
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
Heinrich P.C., Behrmann I., Muller-Newen G., Schaper F., Graeve L. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J. 334:1998;297-314.
-
(1998)
Biochem. J.
, vol.334
, pp. 297-314
-
-
Heinrich, P.C.1
Behrmann, I.2
Muller-Newen, G.3
Schaper, F.4
Graeve, L.5
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