-
1
-
-
0034723290
-
Molecular regulation of hepatic fibrosis: An integrated cellular response to tissue injury
-
Friedman SL: Molecular regulation of hepatic fibrosis: an integrated cellular response to tissue injury. J Biol Chem 2000, 275:2247-2250.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2247-2250
-
-
Friedman, S.L.1
-
2
-
-
0033653571
-
Mechanisms and therapy of hepatic fibrosis: Report of the AASLD Single Topic Basic Research Conference
-
Friedman SL, Maher JJ, Bissell DM: Mechanisms and therapy of hepatic fibrosis: report of the AASLD Single Topic Basic Research Conference. Hepatology 2000, 32:1403-1408.
-
(2000)
Hepatology
, vol.32
, pp. 1403-1408
-
-
Friedman, S.L.1
Maher, J.J.2
Bissell, D.M.3
-
3
-
-
0034810089
-
Cytokine receptors and signaling during stellate cell activation
-
Pinzani M, Marra F: Cytokine receptors and signaling during stellate cell activation. Semin Liver Dis 2001, 21:397-416.
-
(2001)
Semin. Liver Dis.
, vol.21
, pp. 397-416
-
-
Pinzani, M.1
Marra, F.2
-
4
-
-
5444247172
-
Identification, culture, and characterization of pancreatic stellate cells in rats and humans
-
Bachem MG, Schneider E, Gross H, et al.: Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 1998, 115:421-432.
-
(1998)
Gastroenterology
, vol.115
, pp. 421-432
-
-
Bachem, M.G.1
Schneider, E.2
Gross, H.3
-
5
-
-
0034809414
-
Stellate cell behavior during resolution of liver injury
-
Iredale JP: Stellate cell behavior during resolution of liver injury. Semin Liver Dis 2001, 21:427-436.
-
(2001)
Semin. Liver Dis.
, vol.21
, pp. 427-436
-
-
Iredale, J.P.1
-
6
-
-
0028170153
-
Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture
-
Wong L, Yamasaki G, Johnson RJ, Friedman SL: Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture. J Clin Invest 1994, 94:1563-1569.
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 1563-1569
-
-
Wong, L.1
Yamasaki, G.2
Johnson, R.J.3
Friedman, S.L.4
-
7
-
-
0034804406
-
Hepatic blood flow regulation by stellate cells in normal and injured liver
-
Rockey DC: Hepatic blood flow regulation by stellate cells in normal and injured liver. Semin Liver Dis 2001, 21:337-350.
-
(2001)
Semin. Liver Dis.
, vol.21
, pp. 337-350
-
-
Rockey, D.C.1
-
8
-
-
0036238984
-
Effects of endothelins on hepatic stellate cell synthesis of endothelin-1 during hepatic wound healing
-
Shao R, Rockey DC: Effects of endothelins on hepatic stellate cell synthesis of endothelin-1 during hepatic wound healing. J Cell Physiol 2002, 191:342-350.
-
(2002)
J. Cell Physiol.
, vol.191
, pp. 342-350
-
-
Shao, R.1
Rockey, D.C.2
-
9
-
-
0036281460
-
Effects and regulation of connective tissue growth factor on hepatic stellate cells
-
Paradis V, Dargere D, Bonvoust F, et al.: Effects and regulation of connective tissue growth factor on hepatic stellate cells. Lab Invest 2002, 82:767-774.
-
(2002)
Lab. Invest.
, vol.82
, pp. 767-774
-
-
Paradis, V.1
Dargere, D.2
Bonvoust, F.3
-
10
-
-
0036204924
-
Leptin in hepatic fibrosis: Evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice
-
Saxena NK, Ikeda K, Rockey DC, et al.: Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice. Hepatology 2002, 35:762-771.
-
(2002)
Hepatology
, vol.35
, pp. 762-771
-
-
Saxena, N.K.1
Ikeda, K.2
Rockey, D.C.3
-
11
-
-
0034927064
-
Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals
-
Ikejima K, Honda H, Yoshikawa M, et al.: Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals. Hepatology 2001, 34:288-297.
-
(2001)
Hepatology
, vol.34
, pp. 288-297
-
-
Ikejima, K.1
Honda, H.2
Yoshikawa, M.3
-
12
-
-
0034814405
-
Extracellular matrix degradation and the role of stellate cells
-
Benyon D, Arthur MJP: Extracellular matrix degradation and the role of stellate cells. Semin Liver Dis 2001, 21:373-384.
-
(2001)
Semin. Liver Dis.
, vol.21
, pp. 373-384
-
-
Benyon, D.1
Arthur, M.J.P.2
-
13
-
-
0031018997
-
Tissue inhibitors of metalloproteinases in liver fibrosis
-
Iredale JP: Tissue inhibitors of metalloproteinases in liver fibrosis. Int J Biochem Cell Biol 1997, 29:43-54.
-
(1997)
Int. J. Biochem. Cell Biol.
, vol.29
, pp. 43-54
-
-
Iredale, J.P.1
-
14
-
-
0032934278
-
Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells
-
Marra F, Romanelli RG, Pastacaldi S, et al.: Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells. Hepatology 1999, 29:140-148.
-
(1999)
Hepatology
, vol.29
, pp. 140-148
-
-
Marra, F.1
Romanelli, R.G.2
Pastacaldi, S.3
-
15
-
-
0033061550
-
In vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation
-
Ikeda K, Wakahara T, Wang YQ et al.: In vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation. Hepatology 1999, 29:1760-1767.
-
(1999)
Hepatology
, vol.29
, pp. 1760-1767
-
-
Ikeda, K.1
Wakahara, T.2
Wang, Y.Q.3
-
16
-
-
0034809804
-
Stellate cells as a target for treatment of liver fibrosis
-
Bataller R, Brenner DA: Stellate cells as a target for treatment of liver fibrosis. Semin Liver Dis 2001, 21:437-452.
-
(2001)
Semin. Liver Dis.
, vol.21
, pp. 437-452
-
-
Bataller, R.1
Brenner, D.A.2
-
18
-
-
0035742752
-
Decreasing fibrogenesis: An immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B
-
Kweon YO, Goodman ZD, Dienstag JL, et al.: Decreasing fibrogenesis: an immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B. J Hepatol 2001, 35:749-755.
-
(2001)
J. Hepatol.
, vol.35
, pp. 749-755
-
-
Kweon, Y.O.1
Goodman, Z.D.2
Dienstag, J.L.3
-
19
-
-
0036242165
-
Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C
-
Poynard T, McHutchison J, Manns M, et al.: Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C. Gastroenterology 2002, 122:1303-1313.
-
(2002)
Gastroenterology
, vol.122
, pp. 1303-1313
-
-
Poynard, T.1
McHutchison, J.2
Manns, M.3
-
20
-
-
17144455384
-
Histologic improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy
-
Shiratori Y, Imazeki F, Moriyama M, et al.: Histologic improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy. Ann Intern Med 2000, 132:517-524.
-
(2000)
Ann. Intern. Med.
, vol.132
, pp. 517-524
-
-
Shiratori, Y.1
Imazeki, F.2
Moriyama, M.3
-
21
-
-
0035040359
-
Resolution of cirrhosis in autoimmune hepatitis with corticosteroid therapy
-
Cotler SJ, Jakate S, Jensen DM: Resolution of cirrhosis in autoimmune hepatitis with corticosteroid therapy. J Clin Gastroenterol 2001, 32:428-430.
-
(2001)
J. Clin. Gastroenterol.
, vol.32
, pp. 428-430
-
-
Cotler, S.J.1
Jakate, S.2
Jensen, D.M.3
-
22
-
-
0029922315
-
Metals, oxidative stress, and hepatic fibrogenesis
-
Pietrangelo A: Metals, oxidative stress, and hepatic fibrogenesis. Semin Liver Dis 1996, 16:13-30.
-
(1996)
Semin. Liver Dis.
, vol.16
, pp. 13-30
-
-
Pietrangelo, A.1
-
23
-
-
0030854425
-
A pilot study of the effects of d-alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C
-
Houglum K, Venkataramani A, Lyche K, Chojkier M: A pilot study of the effects of d-alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C. Gastroenterology 1997, 113:1069-1073.
-
(1997)
Gastroenterology
, vol.113
, pp. 1069-1073
-
-
Houglum, K.1
Venkataramani, A.2
Lyche, K.3
Chojkier, M.4
-
24
-
-
0030866199
-
Excess iron induces hepatic oxidative stress and transforming growth factor beta1 in genetic hemochromatosis
-
Houglum K, Ramm GA, Crawford DH, et al.: Excess iron induces hepatic oxidative stress and transforming growth factor beta1 in genetic hemochromatosis. Hepatology 1997, 26:605-610.
-
(1997)
Hepatology
, vol.26
, pp. 605-610
-
-
Houglum, K.1
Ramm, G.A.2
Crawford, D.H.3
-
25
-
-
0028792178
-
Antioxidant activity of silybin in vivo during long-term iron overload in rats
-
Pietrangelo A, Borella F, Casalgrandi G, et al.: Antioxidant activity of silybin in vivo during long-term iron overload in rats. Gastroenterology 1995, 109:1941-1949.
-
(1995)
Gastroenterology
, vol.109
, pp. 1941-1949
-
-
Pietrangelo, A.1
Borella, F.2
Casalgrandi, G.3
-
26
-
-
0024321992
-
Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver
-
Ferenci P, Dragosics B, Dittrich H, et al.: Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatology 1989, 9:105-110.
-
(1989)
J. Hepatology
, vol.9
, pp. 105-110
-
-
Ferenci, P.1
Dragosics, B.2
Dittrich, H.3
-
27
-
-
0028679641
-
Interferon gamma inhibits lipocyte activation and extracellular matrix mRNA expression during experimental liver injury: Implications for treatment of hepatic fibrosis
-
Rockey DC, Chung JJ: Interferon gamma inhibits lipocyte activation and extracellular matrix mRNA expression during experimental liver injury: implications for treatment of hepatic fibrosis. J Invest Med 1994, 42:660-670.
-
(1994)
J. Invest. Med.
, vol.42
, pp. 660-670
-
-
Rockey, D.C.1
Chung, J.J.2
-
28
-
-
0034732249
-
Interferon gamma-1b for the treatment of idiopathic pulmonary fibrosis
-
King TE, Jr: Interferon gamma-1b for the treatment of idiopathic pulmonary fibrosis. N Engl J Med 2000, 342:974-975.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 974-975
-
-
King Jr., T.E.1
-
29
-
-
0033855572
-
Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells
-
Marra F, Efsen E, Romanelli RG, et al.: Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. Gastroenterology 2000, 119:466-478.
-
(2000)
Gastroenterology
, vol.119
, pp. 466-478
-
-
Marra, F.1
Efsen, E.2
Romanelli, R.G.3
-
30
-
-
0036086754
-
Pioglitazone prevents early-phase hepatic fibrogenesis caused by carbon tetrachloride
-
Kon K, Ikejima K, Hirose M, et al.: Pioglitazone prevents early-phase hepatic fibrogenesis caused by carbon tetrachloride. Biochem Biophys Res Commun 2002, 291:55-61.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.291
, pp. 55-61
-
-
Kon, K.1
Ikejima, K.2
Hirose, M.3
-
31
-
-
0036082703
-
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
-
Galli A, Crabb DW, Ceni E, et al.: Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. Gastroenterology 2002, 122:1924-1940.
-
(2002)
Gastroenterology
, vol.122
, pp. 1924-1940
-
-
Galli, A.1
Crabb, D.W.2
Ceni, E.3
-
32
-
-
0035120396
-
A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis
-
Caldwell SH, Hespenheide EE, Redick JA, et al.: A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis. Am J Gastroenterol 2001, 96:519-525.
-
(2001)
Am. J. Gastroenterol.
, vol.96
, pp. 519-525
-
-
Caldwell, S.H.1
Hespenheide, E.E.2
Redick, J.A.3
-
33
-
-
0033862589
-
Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair
-
Frank S, Stallmeyer B, Kampfer H, et al.: Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair. J Clin Invest 2000, 106:501-509.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 501-509
-
-
Frank, S.1
Stallmeyer, B.2
Kampfer, H.3
-
34
-
-
0036022846
-
Leptin is essential for the hepatic fibrogenic response to chronic liver injury
-
Leclercq IA, Farrell GC, Schriemer R, Robertson GR: Leptin is essential for the hepatic fibrogenic response to chronic liver injury. J Hepatol 2002, 37:206-213.
-
(2002)
J. Hepatol.
, vol.37
, pp. 206-213
-
-
Leclercq, I.A.1
Farrell, G.C.2
Schriemer, R.3
Robertson, G.R.4
-
35
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H, et al.: Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001, 344:1038-1042.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
-
36
-
-
0030695252
-
Modulation of growth factor action: Implications for the treatment of cardiovascular diseases
-
Waltenberger J: Modulation of growth factor action: implications for the treatment of cardiovascular diseases. Circulation 1997, 96:4083-4094.
-
(1997)
Circulation
, vol.96
, pp. 4083-4094
-
-
Waltenberger, J.1
-
37
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al.: Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 2001, 344:1052-1056.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
-
38
-
-
0033590105
-
ROCK inhibitor Y-27632 attenuates stellate cell contraction and portal pressure increase induced by endothelin-1
-
Kawada N, Seki S, Kuroki T, Kaneda K: ROCK inhibitor Y-27632 attenuates stellate cell contraction and portal pressure increase induced by endothelin-1. Biochem Biophys Res Commun 1999, 266:296-300.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.266
, pp. 296-300
-
-
Kawada, N.1
Seki, S.2
Kuroki, T.3
Kaneda, K.4
-
39
-
-
0035059634
-
A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine- induced hepatic fibrosis in rats
-
Tada S, Iwamoto H, Nakamuta M, et al.: A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine- induced hepatic fibrosis in rats. J Hepatol 2001, 34:529-536.
-
(2001)
J. Hepatol.
, vol.34
, pp. 529-536
-
-
Tada, S.1
Iwamoto, H.2
Nakamuta, M.3
-
40
-
-
0033607304
-
In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: A potential new therapy for hepatic fibrosis
-
George J, Roulot D, Koteliansky VE, Bissell DM: In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis. Proc Natl Acad Sci U S A 1999, 96:12719-12724.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 12719-12724
-
-
George, J.1
Roulot, D.2
Koteliansky, V.E.3
Bissell, D.M.4
-
41
-
-
0035022130
-
Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta
-
Okuno M, Akita K, Moriwaki H, et al.: Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta. Gastroenterology 2001, 120:1784-1800.
-
(2001)
Gastroenterology
, vol.120
, pp. 1784-1800
-
-
Okuno, M.1
Akita, K.2
Moriwaki, H.3
-
42
-
-
0032903634
-
Hepatocyte growth factor gene therapy of liver cirrhosis in rats
-
Ueki T, Kaneda Y, Tsutsui H, et al.: Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med 1999, 5:226-230.
-
(1999)
Nat. Med.
, vol.5
, pp. 226-230
-
-
Ueki, T.1
Kaneda, Y.2
Tsutsui, H.3
-
43
-
-
0031975486
-
Two novel antifibrotics, HOE 077 and Safironil, modulate stellate cell activation in rat liver injury: Differential effects in males and females
-
Wang YJ, Wang SS, Bickel M, Bissell DM: Two novel antifibrotics, HOE 077 and Safironil, modulate stellate cell activation in rat liver injury: differential effects in males and females. Am J Pathol 1998, 152:279-287.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 279-287
-
-
Wang, Y.J.1
Wang, S.S.2
Bickel, M.3
Bissell, D.M.4
-
44
-
-
0037124123
-
Inhibition of collagen alpha1(I) expression by the 5′ stem-loop as a molecular decoy
-
Stefanovic B, Schnabl B, Brenner DA: inhibition of collagen alpha1(I) expression by the 5′ stem-loop as a molecular decoy. J Biol Chem 2002, 277:18229-18237.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18229-18237
-
-
Stefanovic, B.1
Schnabl, B.2
Brenner, D.A.3
-
45
-
-
0029766854
-
Endothelin antagonism in experimental hepatic fibrosis: Implications for endothelin in the pathogenesis of wound healing
-
Rockey DC, Chung JJ: Endothelin antagonism in experimental hepatic fibrosis: implications for endothelin in the pathogenesis of wound healing. J Clin Invest 1996, 98:1381-1388.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1381-1388
-
-
Rockey, D.C.1
Chung, J.J.2
-
46
-
-
0034121518
-
Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension
-
Yu Q, Shao R, Qian HS, et al.: Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension. J Clin Invest 2000, 105:741-748.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 741-748
-
-
Yu, Q.1
Shao, R.2
Qian, H.S.3
-
47
-
-
0032146551
-
Mechanisms of spontaneous resolution of rat liver fibrosis: Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
-
Iredale JP, Benyon RC, Pickering J, et al.: Mechanisms of spontaneous resolution of rat liver fibrosis: hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 1998, 102:538-549.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 538-549
-
-
Iredale, J.P.1
Benyon, R.C.2
Pickering, J.3
-
48
-
-
0034830886
-
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
-
Wright MC, Issa R, Smart DE, et al.: Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats. Gastroenterology 2001, 121:685-698.
-
(2001)
Gastroenterology
, vol.121
, pp. 685-698
-
-
Wright, M.C.1
Issa, R.2
Smart, D.E.3
-
49
-
-
0034567343
-
Liver cirrhosis is reverted by urokinase-type plasminogen activator gene therapy
-
Salgado S, Garcia J, Vera J, et al.: Liver cirrhosis is reverted by urokinase-type plasminogen activator gene therapy. Mol Ther 2000, 2:545-551.
-
(2000)
Mol. Ther.
, vol.2
, pp. 545-551
-
-
Salgado, S.1
Garcia, J.2
Vera, J.3
-
50
-
-
0036580778
-
Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis
-
Beljaars L, Meijer DK, Poelstra K: Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis. Front Biosci 2002, 7:e214-e222.
-
(2002)
Front Biosci.
, vol.7
-
-
Beljaars, L.1
Meijer, D.K.2
Poelstra, K.3
|