-
2
-
-
0033596127
-
Control of apoptosis by Rel/NF-κB transcription factors
-
Barkett, M., and Gilmore, T.D. (1999). Control of apoptosis by Rel/NF-κB transcription factors. Oncogene 18, 6910-6924.
-
(1999)
Oncogene
, vol.18
, pp. 6910-6924
-
-
Barkett, M.1
Gilmore, T.D.2
-
3
-
-
0031282325
-
Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo
-
Bottger, A., Bottger, V., Sparks, A., Liu, W.L., Howard, S.F., and Lane, D.P. (1997). Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo. Curr. Biol. 7, 860-869.
-
(1997)
Curr. Biol.
, vol.7
, pp. 860-869
-
-
Bottger, A.1
Bottger, V.2
Sparks, A.3
Liu, W.L.4
Howard, S.F.5
Lane, D.P.6
-
4
-
-
0029916320
-
Tissue-specific inactivation of p53 tumor suppression in the mouse
-
Bowman, T., Symonds, H., Gu, L., Yin, C., Oren, M., and Van Dyke, T. (1996). Tissue-specific inactivation of p53 tumor suppression in the mouse. Genes Dev. 10, 826-835.
-
(1996)
Genes Dev.
, vol.10
, pp. 826-835
-
-
Bowman, T.1
Symonds, H.2
Gu, L.3
Yin, C.4
Oren, M.5
Van Dyke, T.6
-
5
-
-
0033596129
-
Epstein-Barr virus transformation: Involvement of latent membrane protein 1-mediated activation of NF-κB
-
Cahir McFarland, E.D., Izumi, K.M., and Mosialos, G. (1999). Epstein-Barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-κB. Oncogene 18, 6959-6964.
-
(1999)
Oncogene
, vol.18
, pp. 6959-6964
-
-
Cahir McFarland, E.D.1
Izumi, K.M.2
Mosialos, G.3
-
6
-
-
0034710870
-
Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage
-
Chao, C., Saito, S., Anderson, C.W., Appella, E., and Xu, Y. (2000). Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage. Proc. Natl. Acad. Sci. USA 97, 11936-11941.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11936-11941
-
-
Chao, C.1
Saito, S.2
Anderson, C.W.3
Appella, E.4
Xu, Y.5
-
7
-
-
0029146930
-
Signal-induced site-specific phosphorylation targets IκB alpha to the ubiquitin-proteasome pathway
-
Chen, Z., Hagler, J., Palombella, V.J., Melandri, F., Scherer, D., Ballard, D., and Maniatis, T. (1995). Signal-induced site-specific phosphorylation targets IκB alpha to the ubiquitin-proteasome pathway. Genes Dev. 9, 1586-1597.
-
(1995)
Genes Dev.
, vol.9
, pp. 1586-1597
-
-
Chen, Z.1
Hagler, J.2
Palombella, V.J.3
Melandri, F.4
Scherer, D.5
Ballard, D.6
Maniatis, T.7
-
8
-
-
0029802591
-
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
-
Chen, X., Ko, L.J., Jayaraman, L., and Prives, C. (1996). p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev. 10, 2438-2451.
-
(1996)
Genes Dev.
, vol.10
, pp. 2438-2451
-
-
Chen, X.1
Ko, L.J.2
Jayaraman, L.3
Prives, C.4
-
9
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo, C., Latres, E., Drobnjak, M., Oliva, M.R., Pollack, D., Woodruff, J.M., Marechal, V., Chen, J., Brennan, M.F., and Levine, A.J. (1994). Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res. 54, 794-799.
-
(1994)
Cancer Res.
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drobnjak, M.3
Oliva, M.R.4
Pollack, D.5
Woodruff, J.M.6
Marechal, V.7
Chen, J.8
Brennan, M.F.9
Levine, A.J.10
-
10
-
-
0033177897
-
NF-κB and chemoresistance: Potentiation of cancer drugs via inhibition of NF-κB
-
Cusack, J.C., Liu, R., and Baldwin, A.S. (1999). NF-κB and chemoresistance: potentiation of cancer drugs via inhibition of NF-κB. Drug Resist Updat 2, 271-273.
-
(1999)
Drug Resist Updat
, vol.2
, pp. 271-273
-
-
Cusack, J.C.1
Liu, R.2
Baldwin, A.S.3
-
11
-
-
0034192390
-
Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]- carbonyloxycamptothecin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-κB activation
-
Cusack, J.C., Jr., Liu, R., and Baldwin, A.S., Jr. (2000). Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]- carbonyloxycamptothecin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-κB activation. Cancer Res. 60, 2323-2330.
-
(2000)
Cancer Res.
, vol.60
, pp. 2323-2330
-
-
Cusack Jr., J.C.1
Liu, R.2
Baldwin Jr., A.S.3
-
12
-
-
0035328584
-
Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: Implications for systemic nuclear factor-κB inhibition
-
Cusack, J.C., Jr., Liu, R., Houston, M., Abendroth, K., Elliott, P.J., Adams, J., and Baldwin, A.S., Jr. (2001). Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-κB inhibition. Cancer Res. 61, 3535-3540.
-
(2001)
Cancer Res.
, vol.61
, pp. 3535-3540
-
-
Cusack Jr., J.C.1
Liu, R.2
Houston, M.3
Abendroth, K.4
Elliott, P.J.5
Adams, J.6
Baldwin Jr., A.S.7
-
13
-
-
0027251720
-
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B
-
Debbas, M., and White, E. (1993). Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev. 7, 546-554.
-
(1993)
Genes Dev.
, vol.7
, pp. 546-554
-
-
Debbas, M.1
White, E.2
-
14
-
-
0027363407
-
NF-κB activation by ultraviolet light not dependent on a nuclear signal
-
Devary, Y., Rosette, C., DiDonato, J.A., and Karin, M. (1993). NF-κB activation by ultraviolet light not dependent on a nuclear signal. Science 261, 1442-1445.
-
(1993)
Science
, vol.261
, pp. 1442-1445
-
-
Devary, Y.1
Rosette, C.2
Didonato, J.A.3
Karin, M.4
-
15
-
-
0032570820
-
Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells
-
Donato, N.J., and Perez, M. (1998). Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells. J. Biol. Chem. 273, 5067-5072.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5067-5072
-
-
Donato, N.J.1
Perez, M.2
-
16
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry, W.S., Tokino, T., Velculescu, V.E., Levy, D.B., Parsons, R., Trent, J.M., Lin, D., Mercer, W.E., Kinzler, K.W., and Vogelstein, B. (1993). WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
17
-
-
0037041392
-
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
-
Flores, E.R., Tsai, K.Y., Crowley, D., Sengupta, S., Yang, A., McKeon, F., and Jacks, T. (2002). p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 416, 560-564.
-
(2002)
Nature
, vol.416
, pp. 560-564
-
-
Flores, E.R.1
Tsai, K.Y.2
Crowley, D.3
Sengupta, S.4
Yang, A.5
McKeon, F.6
Jacks, T.7
-
18
-
-
0029783722
-
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
-
Friedlander, P., Haupt, Y., Prives, C., and Oren, M. (1996). A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis. Mol. Cell. Biol. 16, 4961-4971.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4961-4971
-
-
Friedlander, P.1
Haupt, Y.2
Prives, C.3
Oren, M.4
-
19
-
-
0033596128
-
Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel
-
Gilmore, T.D. (1999). Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel. Oncogene 18, 6925-6937.
-
(1999)
Oncogene
, vol.18
, pp. 6925-6937
-
-
Gilmore, T.D.1
-
20
-
-
0028110809
-
Hypoxia induces accumulation of p53 protein, but activation of a G1- Phase checkpoint by low-oxygen conditions is independent of p53 status
-
Graeber, T.G., Peterson, J.F., Tsai, M., Monica, K., Fornace, A.J., Jr., and Giaccia, A.J. (1994). Hypoxia induces accumulation of p53 protein, but activation of a G1- phase checkpoint by low-oxygen conditions is independent of p53 status. Mol. Cell. Biol. 14, 6264-6277.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6264-6277
-
-
Graeber, T.G.1
Peterson, J.F.2
Tsai, M.3
Monica, K.4
Fornace Jr., A.J.5
Giaccia, A.J.6
-
21
-
-
0026303190
-
p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts
-
Harvey, D.M., and Levine, A.J. (1991). p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev. 5, 2375-2385.
-
(1991)
Genes Dev.
, vol.5
, pp. 2375-2385
-
-
Harvey, D.M.1
Levine, A.J.2
-
22
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y., Maya, R., Kazaz, A., and Oren, M. (1997). Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
23
-
-
0032485072
-
Nuclear factor-κB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug
-
Hellin, A.C., Calmant, P., Gielen, J., Bours, V., and Merville, M.P. (1998). Nuclear factor-κB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug. Oncogene 16, 1187-1195.
-
(1998)
Oncogene
, vol.16
, pp. 1187-1195
-
-
Hellin, A.C.1
Calmant, P.2
Gielen, J.3
Bours, V.4
Merville, M.P.5
-
24
-
-
0028108985
-
Database of p53 gene somatic mutations in human tumors and cell lines
-
Hollstein, M., Rice, K., Greenblatt, M.S., Soussi, T., Fuchs, R., Sorlie, T., Hovig, E., Smith-Sorensen, B., Montesano, R., and Harris, C.C. (1994). Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res. 22, 3551-3555.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 3551-3555
-
-
Hollstein, M.1
Rice, K.2
Greenblatt, M.S.3
Soussi, T.4
Fuchs, R.5
Sorlie, T.6
Hovig, E.7
Smith-Sorensen, B.8
Montesano, R.9
Harris, C.C.10
-
25
-
-
0033521621
-
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53
-
Honda, R., and Yasuda, H. (1999). Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53. EMBO J. 18, 22-27.
-
(1999)
EMBO J.
, vol.18
, pp. 22-27
-
-
Honda, R.1
Yasuda, H.2
-
26
-
-
0034714369
-
DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53- Independent post-transcriptional mechanisms
-
Hsing, A., Faller, D.V., and Vaziri, C. (2000). DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53- independent post-transcriptional mechanisms. J. Biol. Chem. 275, 26024-26031.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26024-26031
-
-
Hsing, A.1
Faller, D.V.2
Vaziri, C.3
-
27
-
-
0029897210
-
Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest
-
Huang, L.C., Clarkin, K.C., and Wahl, G.M. (1996). Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest. Proc. Natl. Acad. Sci. USA 93, 4827-4832.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4827-4832
-
-
Huang, L.C.1
Clarkin, K.C.2
Wahl, G.M.3
-
28
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-κB activity
-
Karin, M., and Ben-Neriah, Y. (2000). Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu. Rev. Immunol. 18, 621-663.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
29
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
Kubbutat, M.H., Jones, S.N., and Vousden, K.H. (1997). Regulation of p53 stability by Mdm2. Nature 387, 299-303.
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
30
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine, A.J. (1997). p53, the cellular gatekeeper for growth and division. Cell 88, 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
31
-
-
0033563227
-
IKK1-deficient mice exhibit abnormal development of skin and skeleton
-
Li, Q., Lu, Q., Hwang, J.Y., Buscher, D., Lee, K.F., Izpisua-Belmonte, J.C., and Verma, I.M. (1999a). IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes Dev. 13, 1322-1328.
-
(1999)
Genes Dev.
, vol.13
, pp. 1322-1328
-
-
Li, Q.1
Lu, Q.2
Hwang, J.Y.3
Buscher, D.4
Lee, K.F.5
Izpisua-Belmonte, J.C.6
Verma, I.M.7
-
32
-
-
0033537739
-
Severe liver degeneration in mice lacking the IκB kinase 2 gene
-
Li, Q., Van Antwerp, D., Mercurio, F., Lee, K.F., and Verma, I.M. (1999b). Severe liver degeneration in mice lacking the IκB kinase 2 gene. Science 284, 321-325.
-
(1999)
Science
, vol.284
, pp. 321-325
-
-
Li, Q.1
Van Antwerp, D.2
Mercurio, F.3
Lee, K.F.4
Verma, I.M.5
-
33
-
-
0033532386
-
The IKKbeta subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis
-
Li, Z.W., Chu, W., Hu, Y., Delhase, M., Deerinck, T., Ellisman, M., Johnson, R., and Karin, M. (1999c). The IKKbeta subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis. J. Exp. Med. 189, 1839-1845.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1839-1845
-
-
Li, Z.W.1
Chu, W.2
Hu, Y.3
Delhase, M.4
Deerinck, T.5
Ellisman, M.6
Johnson, R.7
Karin, M.8
-
34
-
-
0034661272
-
Complete lack of NF-κB activity in IKK1 and IKK2 double-deficient mice: Additional defect in neurulation
-
Li, Q., Estepa, G., Memet, S., Israel, A., and Verma, I.M. (2000). Complete lack of NF-κB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation. Genes Dev. 14, 1729-1733.
-
(2000)
Genes Dev.
, vol.14
, pp. 1729-1733
-
-
Li, Q.1
Estepa, G.2
Memet, S.3
Israel, A.4
Verma, I.M.5
-
35
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe, S.W., Ruley, H.E., Jacks, T., and Housman, D.E. (1993a). p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74, 957-967.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
36
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe, S.W., Schmitt, E.M., Smith, S.W., Osborne, B.A., and Jacks, T. (1993b). p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362, 847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
37
-
-
0030612937
-
Requirement of NF-κB activation to suppress p53-independent apoptosis induced by oncogenic Ras
-
Mayo, M.W., Wang, C.Y., Cogswell, P.C., Rogers-Graham, K.S., Lowe, S.W., Der, C.J., and Baldwin, A.S., Jr. (1997). Requirement of NF-κB activation to suppress p53-independent apoptosis induced by oncogenic Ras. Science 278, 1812-1815.
-
(1997)
Science
, vol.278
, pp. 1812-1815
-
-
Mayo, M.W.1
Wang, C.Y.2
Cogswell, P.C.3
Rogers-Graham, K.S.4
Lowe, S.W.5
Der, C.J.6
Baldwin Jr., A.S.7
-
38
-
-
0030070724
-
Efficient generation of recombinant adenoviruses using adenovirus DNA- terminal protein complex and a cosmid bearing the full-length virus genome
-
Miyake, S., Makimura, M., Kanegae, Y., Harada, S., Sato, Y., Takamori, K., Tokuda, C., and Saito, I. (1996). Efficient generation of recombinant adenoviruses using adenovirus DNA- terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl. Acad. Sci. USA 93, 1320-1324.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1320-1324
-
-
Miyake, S.1
Makimura, M.2
Kanegae, Y.3
Harada, S.4
Sato, Y.5
Takamori, K.6
Tokuda, C.7
Saito, I.8
-
39
-
-
0030927167
-
Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth
-
Nakshatri, H., Bhat-Nakshatri, P., Martin, D.A., Goulet, R.J., and Sledge, G.W. (1997). Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth. Mol. Cell. Biol. 17, 3629-3639.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3629-3639
-
-
Nakshatri, H.1
Bhat-Nakshatri, P.2
Martin, D.A.3
Goulet, R.J.4
Sledge, G.W.5
-
40
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner, J.D., Kinzler, K.W., Meltzer, P.S., George, D.L., and Vogelstein, B. (1992). Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 358, 80-83.
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
41
-
-
0033579412
-
Regulation of the p53 tumor suppressor protein
-
Oren, M. (1999). Regulation of the p53 tumor suppressor protein. J. Biol. Chem. 274, 36031-36034.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36031-36034
-
-
Oren, M.1
-
42
-
-
0032478085
-
BRCA1 regulates p53-dependent gene expression
-
Ouchi, T., Monteiro, A.N., August, A., Aaronson, S.A., and Hanafusa, H. (1998). BRCA1 regulates p53-dependent gene expression. Proc. Natl. Acad. Sci. USA 95, 2302-2306.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2302-2306
-
-
Ouchi, T.1
Monteiro, A.N.2
August, A.3
Aaronson, S.A.4
Hanafusa, H.5
-
43
-
-
0033596121
-
Activators and target genes of Rel/NF-κB transcription factors
-
Pahl, H.L. (1999). Activators and target genes of Rel/NF-κB transcription factors. Oncogene 18, 6853-6866.
-
(1999)
Oncogene
, vol.18
, pp. 6853-6866
-
-
Pahl, H.L.1
-
44
-
-
0029811984
-
Genetic determinants of p53-induced apoptosis and growth arrest
-
Polyak, K., Waldman, T., He, T.C., Kinzler, K.W., and Vogelstein, B. (1996). Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev. 10, 1945-1952.
-
(1996)
Genes Dev.
, vol.10
, pp. 1945-1952
-
-
Polyak, K.1
Waldman, T.2
He, T.C.3
Kinzler, K.W.4
Vogelstein, B.5
-
45
-
-
0032475878
-
Signaling to p53: Breaking the MDM2-p53 circuit
-
Prives, C. (1998). Signaling to p53: breaking the MDM2-p53 circuit. Cell 95, 5-8.
-
(1998)
Cell
, vol.95
, pp. 5-8
-
-
Prives, C.1
-
46
-
-
0033596124
-
Aberrant rel/nfkb genes and activity in human cancer
-
Rayet, B., and Gelinas, C. (1999). Aberrant rel/nfkb genes and activity in human cancer. Oncogene 18, 6938-6947.
-
(1999)
Oncogene
, vol.18
, pp. 6938-6947
-
-
Rayet, B.1
Gelinas, C.2
-
47
-
-
0034644506
-
Opposing effects of Ras on p53: Transcriptional activation of mdm2 and induction of p19ARF
-
Ries, S., Biederer, C., Woods, D., Shifman, O., Shirasawa, S., Sasazuki, T., McMahon, M., Oren, M., and McCormick, F. (2000). Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF. Cell 103, 321-330.
-
(2000)
Cell
, vol.103
, pp. 321-330
-
-
Ries, S.1
Biederer, C.2
Woods, D.3
Shifman, O.4
Shirasawa, S.5
Sasazuki, T.6
McMahon, M.7
Oren, M.8
McCormick, F.9
-
48
-
-
0034689773
-
Role of NF-κB in p53-mediated programmed cell death
-
Ryan, K.M., Ernst, M.K., Rice, N.R., and Vousden, K.H. (2000). Role of NF-κB in p53-mediated programmed cell death. Nature 404, 892-897.
-
(2000)
Nature
, vol.404
, pp. 892-897
-
-
Ryan, K.M.1
Ernst, M.K.2
Rice, N.R.3
Vousden, K.H.4
-
49
-
-
17944378526
-
Activation by IKKalpha of a second, evolutionary conserved, NF-κB signaling pathway
-
Senftleben, U., Cao, Y., Xiao, G., Greten, F.R., Krahn, G., Bonizzi, G., Chen, Y., Hu, Y., Fong, A., Sun, S.C., and Karin, M. (2001). Activation by IKKalpha of a second, evolutionary conserved, NF-κB signaling pathway. Science 293, 1495-1499.
-
(2001)
Science
, vol.293
, pp. 1495-1499
-
-
Senftleben, U.1
Cao, Y.2
Xiao, G.3
Greten, F.R.4
Krahn, G.5
Bonizzi, G.6
Chen, Y.7
Hu, Y.8
Fong, A.9
Sun, S.C.10
Karin, M.11
-
50
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano, M., Lin, A.W., McCurrach, M.E., Beach, D., and Lowe, S.W. (1997). Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88, 593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
51
-
-
0032191393
-
Tumor surveillance via the ARF-p53 pathway
-
Sherr, C.J. (1998). Tumor surveillance via the ARF-p53 pathway. Genes Dev. 12, 2984-2991.
-
(1998)
Genes Dev.
, vol.12
, pp. 2984-2991
-
-
Sherr, C.J.1
-
52
-
-
0031440245
-
Aberrant nuclear factor-κB/Rel expression and the pathogenesis of breast cancer
-
Sovak, M.A., Bellas, R.E., Kim, D.W., Zanieski, G.J., Rogers, A.E., Traish, A.M., and Sonenshein, G.E. (1997). Aberrant nuclear factor-κB/Rel expression and the pathogenesis of breast cancer. J. Clin. Invest. 100, 2952-2960.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2952-2960
-
-
Sovak, M.A.1
Bellas, R.E.2
Kim, D.W.3
Zanieski, G.J.4
Rogers, A.E.5
Traish, A.M.6
Sonenshein, G.E.7
-
53
-
-
0033596125
-
Persistent activation of NF-κB by the tax transforming protein of HTLV-1: Hijacking cellular IκB kinases
-
Sun, S.C., and Ballard, D.W. (1999). Persistent activation of NF-κB by the tax transforming protein of HTLV-1: hijacking cellular IκB kinases. Oncogene 18, 6948-6958.
-
(1999)
Oncogene
, vol.18
, pp. 6948-6958
-
-
Sun, S.C.1
Ballard, D.W.2
-
54
-
-
0029007316
-
Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression
-
Sun, X., Shimizu, H., and Yamamoto, K. (1995). Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression. Mol. Cell. Biol. 15, 4489-4496.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4489-4496
-
-
Sun, X.1
Shimizu, H.2
Yamamoto, K.3
-
55
-
-
0033537757
-
Limb and skin abnormalities in mice lacking IKKalpha
-
Takeda, K., Takeuchi, O., Tsujimura, T., Itami, S., Adachi, O., Kawai, T., Sanjo, H., Yoshikawa, K., Terada, N., and Akira, S. (1999). Limb and skin abnormalities in mice lacking IKKalpha. Science 284, 313-316.
-
(1999)
Science
, vol.284
, pp. 313-316
-
-
Takeda, K.1
Takeuchi, O.2
Tsujimura, T.3
Itami, S.4
Adachi, O.5
Kawai, T.6
Sanjo, H.7
Yoshikawa, K.8
Terada, N.9
Akira, S.10
-
56
-
-
0033119952
-
Embryonic lethality, liver degeneration, and impaired NF-κB activation in IKK-beta-deficient mice
-
Tanaka, M., Fuentes, M.E., Yamaguchi, K., Durnin, M.H., Dalrymple, S.A., Hardy, K.L., and Goeddel, D.V. (1999). Embryonic lethality, liver degeneration, and impaired NF-κB activation in IKK-beta-deficient mice. Immunity 10, 421-429.
-
(1999)
Immunity
, vol.10
, pp. 421-429
-
-
Tanaka, M.1
Fuentes, M.E.2
Yamaguchi, K.3
Durnin, M.H.4
Dalrymple, S.A.5
Hardy, K.L.6
Goeddel, D.V.7
-
57
-
-
0029992609
-
Suppression of TNF-alpha-induced apoptosis by NF-κB
-
Van Antwerp, D.J., Martin, S.J., Kafri, T., Green, D.R., and Verma, I.M. (1996). Suppression of TNF-alpha-induced apoptosis by NF-κB. Science 274, 787-789.
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
58
-
-
0028971289
-
Rel/NF-κB/IκB family: Intimate tales of association and dissociation
-
Verma, I.M., Stevenson, J.K., Schwarz, E.M., Van Antwerp, D., and Miyamoto, S. (1995). Rel/NF-κB/IκB family: intimate tales of association and dissociation. Genes Dev. 9, 2723-2735.
-
(1995)
Genes Dev.
, vol.9
, pp. 2723-2735
-
-
Verma, I.M.1
Stevenson, J.K.2
Schwarz, E.M.3
Van Antwerp, D.4
Miyamoto, S.5
-
59
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
-
Wang, C.Y., Mayo, M.W., and Baldwin, A.S., Jr. (1996). TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 274, 784-787.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
60
-
-
0032905030
-
Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB
-
Wang, C.Y., Cusack, J.C., Jr., Liu, R., and Baldwin, A.S., Jr. (1999). Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB. Nat. Med. 5, 412-417.
-
(1999)
Nat. Med.
, vol.5
, pp. 412-417
-
-
Wang, C.Y.1
Cusack Jr., J.C.2
Liu, R.3
Baldwin Jr., A.S.4
-
61
-
-
0032954928
-
Transcriptional cross talk between NF-κB and p53
-
Webster, G.A., and Perkins, N.D. (1999). Transcriptional cross talk between NF-κB and p53. Mol. Cell. Biol. 19, 3485-3495.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3485-3495
-
-
Webster, G.A.1
Perkins, N.D.2
-
62
-
-
0028167599
-
NF-κB activation of p53. A potential mechanism for suppressing cell growth in response to stress
-
Wu, H., and Lozano, G. (1994). NF-κB activation of p53. A potential mechanism for suppressing cell growth in response to stress. J. Biol. Chem. 269, 20067-20074.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 20067-20074
-
-
Wu, H.1
Lozano, G.2
-
63
-
-
0027244853
-
The p53-mdm-2 autoregulatory feedback loop
-
Wu, X., Bayle, J.H., Olson, D., and Levine, A.J. (1993). The p53-mdm-2 autoregulatory feedback loop. Genes Dev. 7, 1126-1132.
-
(1993)
Genes Dev.
, vol.7
, pp. 1126-1132
-
-
Wu, X.1
Bayle, J.H.2
Olson, D.3
Levine, A.J.4
-
64
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation
-
Yamaoka, S., Courtois, G., Bessia, C., Whiteside, S.T., Weil, R., Agou, F., Kirk, H.E., Kay, R.J., and Israel, A. (1998). Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation. Cell 93, 1231-1240.
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
Courtois, G.2
Bessia, C.3
Whiteside, S.T.4
Weil, R.5
Agou, F.6
Kirk, H.E.7
Kay, R.J.8
Israel, A.9
-
65
-
-
0026801977
-
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
-
Yin, Y., Tainsky, M.A., Bischoff, F.Z., Strong, L.C., and Wahl, G.M. (1992). Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70, 937-948.
-
(1992)
Cell
, vol.70
, pp. 937-948
-
-
Yin, Y.1
Tainsky, M.A.2
Bischoff, F.Z.3
Strong, L.C.4
Wahl, G.M.5
-
66
-
-
0035736487
-
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
-
Zhou, B.P., Liao, Y., Xia, W., Zou, Y., Spohn, B., and Hung, M.C. (2001). HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat. Cell Biol. 3, 973-982.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 973-982
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Zou, Y.4
Spohn, B.5
Hung, M.C.6
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