-
1
-
-
12944321452
-
Symptomatic treatment of chronic neuropathic pain with gabapentin clinical practice and research perspective
-
Backonja M-M: Symptomatic treatment of chronic neuropathic pain with gabapentin clinical practice and research perspective. Current Neuropharmacology 2003, 1:199-202.
-
(2003)
Current Neuropharmacology
, vol.1
, pp. 199-202
-
-
Backonja, M.-M.1
-
2
-
-
11844293719
-
Pharmacology and therapeutics of gabapentin in the treatment of Psychiatric Disorders; Present and Future Perspectives
-
Megna JL, Iqbal MM, Aneja A: Pharmacology and therapeutics of gabapentin in the treatment of Psychiatric Disorders; Present and Future Perspectives. Current Neuropharmacology 2003, 1: 87-97.
-
(2003)
Current Neuropharmacology
, vol.1
, pp. 187-197
-
-
Megna, J.L.1
Iqbal, M.M.2
Aneja, A.3
-
3
-
-
0028129087
-
Gabapentin as add on therapy for refractory partial epilepsy: Results of five placebo controlled trials
-
Leiderman DB: Gabapentin as add on therapy for refractory partial epilepsy: results of five placebo controlled trials. Epilesia 35:s75-s76.
-
Epilesia
, vol.35
-
-
Leiderman, D.B.1
-
4
-
-
0031883542
-
A summary of mechanistic hypotheses of gabapentin pharmacology
-
Taylor CP, Gee NS, Su T-Z, Kocsis JD, Welty DF, Brown JP, Dooley DJ, Boden P, Singh L: A summary of mechanistic hypotheses of gabapentin pharmacology. Epilepsy Res 1998, 29:233-49.
-
(1998)
Epilepsy Res.
, vol.29
, pp. 233-249
-
-
Taylor, C.P.1
Gee, N.S.2
Su, T.-Z.3
Kocsis, J.D.4
Welty, D.F.5
Brown, J.P.6
Dooley, D.J.7
Boden, P.8
Singh, L.9
-
5
-
-
2342556228
-
Cellular actions of gabapentin and related compounds on cultured sensory neurones
-
Scott RH, Martin DJ, McClelland D: Cellular actions of gabapentin and related compounds on cultured sensory neurones. Current Neuropharmacology 2003, 1:219-35.
-
(2003)
Current Neuropharmacology
, vol.1
, pp. 219-235
-
-
Scott, R.H.1
Martin, D.J.2
McClelland, D.3
-
6
-
-
0038702425
-
Cellular and molecular action of the putative GABA-mimetic, gabapentin
-
Maneuf YP, Gonzalez MI, Sutton KG, Chung F-Z, Pinnock RD, Lee K: Cellular and molecular action of the putative GABA-mimetic, gabapentin. Cell Mol Life Sci 2003, 60:742-750.
-
(2003)
Cell Mol. Life Sci.
, vol.60
, pp. 742-750
-
-
Maneuf, Y.P.1
Gonzalez, M.I.2
Sutton, K.G.3
Chung, F.-Z.4
Pinnock, R.D.5
Lee, K.6
-
7
-
-
0029975930
-
The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha(2)delta subunit of a calcium channel
-
Gee NS, Brown JP, Dissanayake VUK, Offord J, Thurlow R, Woodruff GN: The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha(2)delta subunit of a calcium channel. J Biol Chem 1996, 271:5768-5776.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5768-5776
-
-
Gee, N.S.1
Brown, J.P.2
Dissanayake, V.U.K.3
Offord, J.4
Thurlow, R.5
Woodruff, G.N.6
-
8
-
-
0030796031
-
Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents
-
Field MJ, Oles RJ, Lewis AS, McCleary S, Hughes J, Singh L: Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents. Br J Pharmacol 1997, 121:1513-22.
-
(1997)
Br. J. Pharmacol.
, vol.121
, pp. 1513-1522
-
-
Field, M.J.1
Oles, R.J.2
Lewis, A.S.3
McCleary, S.4
Hughes, J.5
Singh, L.6
-
9
-
-
0031963052
-
Characterization of the effects of gabapentin and 3-isobutyl-gamma-aminobutyric acid on substance P-induced thermal hyperalgesia
-
Partridge BJ, Chaplan SR, Sakamoto E, Yaksh TL: Characterization of the effects of gabapentin and 3-isobutyl-gamma-aminobutyric acid on substance P-induced thermal hyperalgesia. Anestheiology 1998, 88:196-205.
-
(1998)
Anestheiology
, vol.88
, pp. 196-205
-
-
Partridge, B.J.1
Chaplan, S.R.2
Sakamoto, E.3
Yaksh, T.L.4
-
11
-
-
0036155045
-
Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones
-
Sutton KG, Martin DJ, Pinnock RD, Lee K, Scott RH: Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones. Br J Pharmacol 2002, 135: 57-65.
-
(2002)
Br. J. Pharmacol.
, vol.135
, pp. 257-265
-
-
Sutton, K.G.1
Martin, D.J.2
Pinnock, R.D.3
Lee, K.4
Scott, R.H.5
-
12
-
-
0036118498
-
2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel sub-unit expression
-
2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel sub-unit expression. Neuropharmacol 2002, 42:353-66.
-
(2002)
Neuropharmacol.
, vol.42
, pp. 353-366
-
-
Martin, D.J.1
McClelland, D.2
Herd, M.B.3
Sutton, K.G.4
Hall, M.D.5
Lee, K.6
Pinnock, R.D.7
Scott, R.H.8
-
13
-
-
0035164999
-
Gamma-Aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action
-
Ng GYK, Bertrand S, Sullivan R, Ethier N, Wang J, Yergey J, Belley M, Trimble L, Bateman K, Alder L, Smith A, McKernan R, Metters K, O'Neill GP, Lacaille JC, Hebert TE: Gamma-Aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action. Mol Pharmacol 2001, 59:144-52.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 144-152
-
-
Ng, G.Y.K.1
Bertrand, S.2
Sullivan, R.3
Ethier, N.4
Wang, J.5
Yergey, J.6
Belley, M.7
Trimble, L.8
Bateman, K.9
Alder, L.10
Smith, A.11
McKernan, R.12
Metters, K.13
O'Neill, G.P.14
Lacaille, J.C.15
Hebert, T.E.16
-
14
-
-
0034967810
-
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels
-
Bertrand S, Ng GYK, Purisai MG, Wolfe SE, Severidt MW, Nouel D, Robitaille R, Low MJ, O'Neill GP, Metters K, Lacaille JC, Chronwall BM, Morris SJ: The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels. J Pharmacol and Exp Therapeu 2001, 298:15-24.
-
(2001)
J. Pharmacol. and Exp. Therapeu.
, vol.298
, pp. 15-24
-
-
Bertrand, S.1
Ng, G.Y.K.2
Purisai, M.G.3
Wolfe, S.E.4
Severidt, M.W.5
Nouel, D.6
Robitaille, R.7
Low, M.J.8
O'Neill, G.P.9
Metters, K.10
Lacaille, J.C.11
Chronwall, B.M.12
Morris, S.J.13
-
16
-
-
0037746667
-
Different actions of gabapentin and baclofen in hippocampus from weaver mice
-
Bertrand S, Morin F, Lacaille JC: Different actions of gabapentin and baclofen in hippocampus from weaver mice. Hippocampus 2003, 13:525-528.
-
(2003)
Hippocampus
, vol.13
, pp. 525-528
-
-
Bertrand, S.1
Morin, F.2
Lacaille, J.C.3
-
17
-
-
0023944844
-
The agonist effect of Bay K8644 on neuronal calcium channel currents are promoted by G-protein activation
-
Scott RH, Dolphin AC: The agonist effect of Bay K8644 on neuronal calcium channel currents are promoted by G-protein activation. Neurosci Letts 1988, 89:170-175.
-
(1988)
Neurosci. Letts.
, vol.89
, pp. 170-175
-
-
Scott, R.H.1
Dolphin, A.C.2
-
18
-
-
0035282239
-
The effects of gabapentin on different ligand-and voltage-gated currents in isolated cortical neurons
-
Stefani A, Spadoni F, Giacomini P, Lavaroni F, Bernardi G: The effects of gabapentin on different ligand-and voltage-gated currents in isolated cortical neurons. Epilepsy Res 2001, 43: 39-248.
-
(2001)
Epilepsy Res.
, vol.43
, pp. 239-248
-
-
Stefani, A.1
Spadoni, F.2
Giacomini, P.3
Lavaroni, F.4
Bernardi, G.5
-
20
-
-
35848939427
-
2+ sensors with particular reference to the modulation of neuronal excitability
-
2+ sensors with particular reference to the modulation of neuronal excitability. Current Topics in Membranes 2002, 53: 35-166.
-
(2002)
Current Topics in Membranes
, vol.53
, pp. 135-166
-
-
Kenyon, J.L.1
Scott, R.H.2
-
21
-
-
0035170060
-
SCH-202676: An allosteric modulator of both agonist and antagonist binding to G-protein-coupled receptors
-
Fawzi AB, MacDonald D, Benbow LL, Smith-Torhan A, Zhang H, Weig BC, Ho G, Tulshian D, Linder ME, Graziano MP: SCH-202676: An allosteric modulator of both agonist and antagonist binding to G-protein-coupled receptors. Mol Pharmacol 2001, 59:30-37.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 30-37
-
-
Fawzi, A.B.1
MacDonald, D.2
Benbow, L.L.3
Smith-Torhan, A.4
Zhang, H.5
Weig, B.C.6
Ho, G.7
Tulshian, D.8
Linder, M.E.9
Graziano, M.P.10
-
22
-
-
0023922546
-
Photoactivation of intracellular guanosine triphosphate analogues reduces the amplitude and slows the kinetics of voltage-activated calcium channel currents in sensory neurones
-
Dolphin AC, Wootton JF, Scott RH, Trentham DR: Photoactivation of intracellular guanosine triphosphate analogues reduces the amplitude and slows the kinetics of voltage-activated calcium channel currents in sensory neurones. Pflügers Arch 1988, 411: 28-636.
-
(1988)
Pflügers Arch.
, vol.411
, pp. 628-636
-
-
Dolphin, A.C.1
Wootton, J.F.2
Scott, R.H.3
Trentham, D.R.4
-
23
-
-
0024467710
-
Voltage dependent GABA-induced modulation of calcium currents in chick sensory neurones
-
Grassi F, Lux HD: Voltage dependent GABA-induced modulation of calcium currents in chick sensory neurones. Neurosci Letts 1989, 105:113-117.
-
(1989)
Neurosci. Letts.
, vol.105
, pp. 113-117
-
-
Grassi, F.1
Lux, H.D.2
-
25
-
-
0028789867
-
Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA
-
Goldlust A, Su T-Z, Welty DF, Taylor CP, Oxender DL: Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA. Epilepsy Res 1995, 22: -11.
-
(1995)
Epilepsy Res.
, vol.22
, pp. 1-11
-
-
Goldlust, A.1
Su, T.-Z.2
Welty, D.F.3
Taylor, C.P.4
Oxender, D.L.5
-
26
-
-
0025365945
-
Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinase I and II with analogs of adenosine 3′, 5′ -cyclic phosphorothioates
-
Dostmann WRG, Taylor SS, Genieser HG, Jastorff B, Dorskeland SO, Ogreid D: Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinase I and II with analogs of adenosine 3′ , 5′-cyclic phosphorothioates. J Biol Chem 1995, 265: 0484-10491.
-
(1995)
J. Biol. Chem.
, vol.265
, pp. 10484-10491
-
-
Dostmann, W.R.G.1
Taylor, S.S.2
Genieser, H.G.3
Jastorff, B.4
Dorskeland, S.O.5
Ogreid, D.6
-
27
-
-
0031809165
-
Gabapentin inhibits calcium currents in isolated rat brain neurons
-
Stefani A, Spadoni F, Bernardi G: Gabapentin inhibits calcium currents in isolated rat brain neurons. Neuropharmacology 1998, 37:83-91.
-
(1998)
Neuropharmacology
, vol.37
, pp. 83-91
-
-
Stefani, A.1
Spadoni, F.2
Bernardi, G.3
-
31
-
-
0035542921
-
B receptor agonist
-
B receptor agonist. Neuropharmacol 2001, 41:965-975.
-
(2001)
Neuropharmacol.
, vol.41
, pp. 965-975
-
-
Lanneau, C.1
Green, A.2
Hirst, W.D.3
Wise, A.4
Brown, J.T.5
Donnier, E.6
Charles, K.J.7
Wood, M.8
Davies, C.H.9
Pangalos, M.N.10
-
32
-
-
0036259012
-
The anticonvulsant gabapentin (Neurontin) does not act through γ-aminobutyric acid-B receptors
-
Jensen AA, Mosbacher J, Elg S, Lingenhoehl K, Lohmann T, Johansen TN, Abrahamsen B, Mattsson JP, Lehmann A, Bettler B, Brauner-Osborne H: The anticonvulsant gabapentin (Neurontin) does not act through γ-aminobutyric acid-B receptors. Mol Pharmacol 2002, 61:1377-1384.
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 1377-1384
-
-
Jensen, A.A.1
Mosbacher, J.2
Elg, S.3
Lingenhoehl, K.4
Lohmann, T.5
Johansen, T.N.6
Abrahamsen, B.7
Mattsson, J.P.8
Lehmann, A.9
Bettler, B.10
Brauner-Osborne, H.11
-
33
-
-
0035011569
-
ATP channels
-
ATP channels. Naunyn-Schmiedeberg's Arch Pharmacol 2001, 363:537-542.
-
(2001)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.363
, pp. 537-542
-
-
Freiman, T.M.1
Kukolja, J.2
Heinemeyer, J.3
Eckhardt, K.4
Aranda, H.5
Rominger, A.6
Dooley, D.J.7
Zentner, J.8
Feuerstein, T.9
-
34
-
-
0033623176
-
Prostaglandin E-2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A
-
Smith JAM, Davis CL, Burgess GM: Prostaglandin E-2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A. Euro J Neurosci 2000, 12:3250-3258.
-
(2000)
Eur. J. Neurosci.
, vol.12
, pp. 3250-3258
-
-
Smith, J.A.M.1
Davis, C.L.2
Burgess, G.M.3
-
35
-
-
0029162141
-
+ channel that is phosphorylated and modulated by cAMP-dependent protein kinase
-
+ channel that is phosphorylated and modulated by cAMP-dependent protein kinase. J Neurosci 1995, 15:5486-5501.
-
(1995)
J. Neurosci.
, vol.15
, pp. 5486-5501
-
-
Moreno, H.1
Kentros, C.2
Bueno, E.3
Weiser, M.4
Hernandez, A.5
Demiera, E.V.S.6
Ponce, A.7
Thornhill, W.8
Rudy, B.9
-
36
-
-
0141521876
-
ERK integrates PKA and PKC signaling in superficial dorsal horn neurons. II. Modulation of neuronal excitability
-
Hu HJ, Gereau RW: ERK integrates PKA and PKC signaling in superficial dorsal horn neurons. II. Modulation of neuronal excitability. J Neurophysiol 2003, 90:1680-1688.
-
(2003)
J. Neurophysiol.
, vol.90
, pp. 1680-1688
-
-
Hu, H.J.1
Gereau, R.W.2
-
37
-
-
0033118638
-
The cAMP transduction cascade mediates the PGE(2)-induced inhibition of potassium currents in rat sensory neurones
-
Evans AR, Vasko MR, Nicol GD: The cAMP transduction cascade mediates the PGE(2)-induced inhibition of potassium currents in rat sensory neurones. J Physiol (London) 1999, 516: 63-178.
-
(1999)
J. Physiol. (London)
, vol.516
, pp. 163-178
-
-
Evans, A.R.1
Vasko, M.R.2
Nicol, G.D.3
-
38
-
-
0041353433
-
B receptor transduction mechanisms, and cross-talk between protein kinase A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert
-
B receptor transduction mechanisms, and cross-talk between protein kinase A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert. J Physiol (London) 2003, 551:263-276.
-
(2003)
J. Physiol. (London)
, vol.551
, pp. 263-276
-
-
Kubota, H.1
Katsurabayashi, S.2
Moorhouse, A.J.3
Murakami, N.4
Koga, H.5
Akaike, N.6
-
39
-
-
0142243144
-
Conditional protein phosphorylation regulates BK channel activity in rat cerebellar Purkinje neurons
-
Widmer HA, Rowe ICM, Shipston MJ: Conditional protein phosphorylation regulates BK channel activity in rat cerebellar Purkinje neurons. J Physiol (London) 2003, 552:379-391.
-
(2003)
J. Physiol. (London)
, vol.552
, pp. 379-391
-
-
Widmer, H.A.1
Rowe, I.C.M.2
Shipston, M.J.3
-
40
-
-
0141884059
-
Biphasic modulation of voltage-dependent currents of retinal cones by cannabinoid CB1 receptor agonist WIN 55212-2
-
Fan SF, Yazulla S: Biphasic modulation of voltage-dependent currents of retinal cones by cannabinoid CB1 receptor agonist WIN 55212-2. Visual Neurosci 2003, 20:177-188.
-
(2003)
Visual Neurosci.
, vol.20
, pp. 177-188
-
-
Fan, S.F.1
Yazulla, S.2
-
41
-
-
0027977004
-
Limitation by gabapentin of high frequency action potential firing by mouse central neurons in cell culture
-
Wamil AW, McLean MJ: Limitation by gabapentin of high frequency action potential firing by mouse central neurons in cell culture. Epilepsy Res 1994, 17:1-11.
-
(1994)
Epilepsy Res.
, vol.17
, pp. 1-11
-
-
Wamil, A.W.1
McLean, M.J.2
-
42
-
-
0029795902
-
The antiepileptic agent gabapentin (Neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed by D-serine
-
Singh L, Field MJ, Ferris P, Hunter JC, Oles RJ, Williams RG, Woodruff : The antiepileptic agent gabapentin (Neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed by D-serine. Psychopharmacology 1996, 127:1-9.
-
(1996)
Psychopharmacology
, vol.127
, pp. 1-9
-
-
Singh, L.1
Field, M.J.2
Ferris, P.3
Hunter, J.C.4
Oles, R.J.5
Williams, R.G.6
Woodruff, A.7
-
43
-
-
0031838031
-
S-(+)-3-isobutylgaba and its stereoisomer reduces the amount of inflammation and hyperalgesia in an acute arthritis model in the rat
-
Houghton AK, Lu Y, Westlund KN: S-(+)-3-isobutylgaba and its stereoisomer reduces the amount of inflammation and hyperalgesia in an acute arthritis model in the rat. J Pharm & Exp Therap 1998, 285:533-538.
-
(1998)
J. Pharm. & Exp. Therap.
, vol.285
, pp. 533-538
-
-
Houghton, A.K.1
Lu, Y.2
Westlund, K.N.3
-
44
-
-
0035212152
-
Stereospecific effect of pregabalin on ectopic afferent discharges and neuropathic pain induced by sciatic nerve ligation in rats
-
Chen SR, Xu Z, Pan HL: Stereospecific effect of pregabalin on ectopic afferent discharges and neuropathic pain induced by sciatic nerve ligation in rats. Anesthesiology 2001, 95:1473-1479.
-
(2001)
Anesthesiology
, vol.95
, pp. 1473-1479
-
-
Chen, S.R.1
Xu, Z.2
Pan, H.L.3
-
45
-
-
0141738762
-
Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C
-
Fehrenbacher JC, Taylor CP, Vasko MR: Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C. Pain 2003, 105:133-141.
-
(2003)
Pain
, vol.105
, pp. 133-141
-
-
Fehrenbacher, J.C.1
Taylor, C.P.2
Vasko, M.R.3
-
46
-
-
2542482777
-
Drug targets in the voltage-gated calcium channel family: Why some are and some are not
-
Triggle DJ: Drug targets in the voltage-gated calcium channel family: Why some are and some are not. Assay and drug development technologies 2003, 1:719-733.
-
(2003)
Assay and Drug Development Technologies
, vol.1
, pp. 719-733
-
-
Triggle, D.J.1
-
47
-
-
1642580583
-
2+ channels to nociceptive transmission in rat spinal lamina I neurones
-
2+ channels to nociceptive transmission in rat spinal lamina I neurones. Euro J Neurosci 2004, 19:103-111.
-
(2004)
Eur. J. Neurosci.
, vol.19
, pp. 103-111
-
-
Heinke, B.1
Balzer, E.2
Sandkühler, J.3
-
48
-
-
0023159073
-
Calcium channel currents and their inhibition by (-)-baclofen in rat sensory neurones: Modulation by guanine nucleotides
-
Dolphin AC, Scott RH: Calcium channel currents and their inhibition by (-)-baclofen in rat sensory neurones: modulation by guanine nucleotides. J Physiol (London) 1987, 386:1-17.
-
(1987)
J. Physiol. (London)
, vol.386
, pp. 1-17
-
-
Dolphin, A.C.1
Scott, R.H.2
-
49
-
-
0023841480
-
Low cost high intensity flash device for photolysis experiments
-
Rapp G, Guth K: Low cost high intensity flash device for photolysis experiments. Pflügers Arch 1988, 411: 00-203.
-
(1988)
Pflügers Arch.
, vol.411
, pp. 200-203
-
-
Rapp, G.1
Guth, K.2
|