Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones

British Journal of Pharmacology

Volumn 135, Issue 1, 2002, Pages 257-265

  Sutton, K G ^a   Martin, D J ^b   Pinnock, R D ^a   Lee, K ^a   Scott, R H ^b  

^a PFIZER INC   (United States)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Dorsal root ganglia; Fluorescence calcium imaging; Gabapentin; Pain; Patch clamp; Sensory neurones

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; FURA 2; GABAPENTIN; ISOLEUCINE; NIFEDIPINE; POTASSIUM CHLORIDE; RECEPTOR SUBUNIT; SACLOFEN;

ANIMAL CELL; ANTINOCICEPTION; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; DEPOLARIZATION; DOSE RESPONSE; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; IC 50; NERVE CELL CULTURE; NEWBORN; NONHUMAN; PHARMACOLOGY; PRIORITY JOURNAL; RAT; SPINAL GANGLION;

ACETIC ACIDS; AMINES; ANIMALS; ANTICONVULSANTS; CALCIUM; CALCIUM CHANNELS; CELLS, CULTURED; CYCLOHEXANECARBOXYLIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-AMINOBUTYRIC ACID; GANGLIA, SPINAL; MEMBRANE POTENTIALS; NEURONS, AFFERENT; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR;

EID: 0036155045     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704439     Document Type: Article

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