Subtoxic concentration of manganese synergistically potentiates 1-methyl-4-phenylpyridinium-induced neurotoxicity in PC12 cells

Brain Research

Volumn 961, Issue 1, 2003, Pages 131-138

  Wang, Ren Gang ^a   Zhu, Xing Zu ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

1 Methyl 4 phenylpyridinium; Manganese; Neurotoxicity; Parkinson's disease; PC12 cell; Reactive oxygen species

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; CASPASE 3; MANGANESE; NEUROTOXIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LEVEL; CELL STRAIN; CONTROLLED STUDY; DELAYED NEUROTOXICITY; DRUG INDUCED DISEASE; ENZYME ACTIVATION; MOLECULAR PROBE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; REACTION TIME; SIGNAL TRANSDUCTION; TOXICOKINETICS;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; MANGANESE; NEUROTOXINS; OSMOLAR CONCENTRATION; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES;

EID: 0037462296     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)03886-6     Document Type: Article

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