Intracellular dopamine oxidation mediates rotenone-induced apoptosis in PC12 cells

Acta Pharmacologica Sinica

Volumn 26, Issue 1, 2005, Pages 17-26

  Liu, Hua Qing ^a   Zhu, Xing Zu ^a   Weng, En Qi ^b  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b EAST CHINA NORMAL UNIVERSITY   (China)

Author keywords

Deprenyl; Neurotoxicity; Parkinson disease; Reactive oxygen species; Reserpine; Rotenone

Indexed keywords

CASPASE 3; DICHLORODIHYDROFLUORESCEIN DIACETATE; DOPAMINE; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; LACTIC ACID; MONOAMINE OXIDASE B INHIBITOR; REACTIVE OXYGEN METABOLITE; RESERPINE; ROTENONE; SELEGILINE; VESICULAR MONOAMINE TRANSPORTER;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOOXIDATION; CATECHOLAMINE DEPLETION; CELL DAMAGE; CELL STRAIN; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; MITOCHONDRION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; DOPAMINE; L-LACTATE DEHYDROGENASE; LACTIC ACID; MONOAMINE OXIDASE INHIBITORS; OXIDATION-REDUCTION; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; RESERPINE; ROTENONE; SELEGILINE;

EID: 11844269889     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2005.00003.x     Document Type: Article

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