메뉴 건너뛰기




Volumn 63, Issue 16, 2003, Pages 4862-4871

Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN; PROTEIN P53; UNCLASSIFIED DRUG; VIRUS PROTEIN E6; VIRUS PROTEIN E7;

EID: 0042440926     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (280)

References (73)
  • 1
    • 0036511615 scopus 로고    scopus 로고
    • The role of human papillomaviruses in human cancers
    • Münger, K. The role of human papillomaviruses in human cancers. Front. Biosci., 7: d641-649, 2002.
    • (2002) Front. Biosci. , vol.7
    • Münger, K.1
  • 2
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • zur Hausen, H. Papillomaviruses and cancer: from basic studies to clinical application. Nat. Rev. Cancer, 2: 342-350, 2002.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 342-350
    • Zur Hausen, H.1
  • 3
    • 0028348414 scopus 로고
    • Molecular pathogenesis of cancer of the cervix and its causation by specific human papillomavirus types
    • zur Hausen, H. Molecular pathogenesis of cancer of the cervix and its causation by specific human papillomavirus types. Curr. Top. Microbiol. Immunol., 186: 131-156, 1994.
    • (1994) Curr. Top. Microbiol. Immunol. , vol.186 , pp. 131-156
    • Zur Hausen, H.1
  • 4
    • 0029448725 scopus 로고
    • The molecular biology of cervical cancer
    • Münger, K. The molecular biology of cervical cancer. J. Cell. Biochem. Suppl., 23: 55-60, 1995.
    • (1995) J. Cell. Biochem. Suppl. , vol.23 , pp. 55-60
    • Münger, K.1
  • 5
    • 0035956258 scopus 로고    scopus 로고
    • Biological activities and molecular targets of the human papillomavirus E7 oncoprotein
    • Münger, K., Basile, J. R., Duensing, S., Eichten, A., Gonzalez, S. L., Grace, M., and Zacny, V. L. Biological activities and molecular targets of the human papillomavirus E7 oncoprotein. Oncogene, 20; 7888-7898, 2001.
    • (2001) Oncogene , vol.20 , pp. 7888-7898
    • Münger, K.1    Basile, J.R.2    Duensing, S.3    Eichten, A.4    Gonzalez, S.L.5    Grace, M.6    Zacny, V.L.7
  • 7
    • 0035956215 scopus 로고    scopus 로고
    • The human papillomavirus E6 protein and its contribution to malignant progression
    • Mantovani, F., and Banks, L. The human papillomavirus E6 protein and its contribution to malignant progression. Oncogene, 20: 7874-7887, 2001.
    • (2001) Oncogene , vol.20 , pp. 7874-7887
    • Mantovani, F.1    Banks, L.2
  • 8
    • 0030418318 scopus 로고    scopus 로고
    • Interactions of the human papillomavirus E7 protein with cell cycle regulators
    • Jones, D. L., and Münger, K. Interactions of the human papillomavirus E7 protein with cell cycle regulators. Semin. Cancer Biol., 7: 327-337, 1996.
    • (1996) Semin. Cancer Biol. , vol.7 , pp. 327-337
    • Jones, D.L.1    Münger, K.2
  • 9
    • 0031438309 scopus 로고    scopus 로고
    • Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis
    • Jones, D. L., Thompson, D. A., and Münger, K. Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis. Virology, 239: 97-107, 1997.
    • (1997) Virology , vol.239 , pp. 97-107
    • Jones, D.L.1    Thompson, D.A.2    Münger, K.3
  • 10
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus type 16 and 18 promotes the degradation of p53
    • Scheffner, M., Wemess, B., Huibregste, J., and Howley, P. The E6 oncoprotein encoded by human papillomavirus type 16 and 18 promotes the degradation of p53. Cell, 63: 1129-1136, 1990.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Wemess, B.2    Huibregste, J.3    Howley, P.4
  • 11
    • 0029936515 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors
    • Antinore, M. J., Birrer, M. J., Patel, D., Nader, L., and McCance, D. J. The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors. EMBO J., 15: 1950-1960, 1996.
    • (1996) EMBO J. , vol.15 , pp. 1950-1960
    • Antinore, M.J.1    Birrer, M.J.2    Patel, D.3    Nader, L.4    McCance, D.J.5
  • 12
    • 0024368620 scopus 로고
    • The E6 and E7 genes of HPV-18 are sufficient for inducing two-stage in vitro transformation of human keratinocytes
    • Barbosa, M. S., and Schlegel, R. The E6 and E7 genes of HPV-18 are sufficient for inducing two-stage in vitro transformation of human keratinocytes. Oncogene, 4: 1529-1532, 1989.
    • (1989) Oncogene , vol.4 , pp. 1529-1532
    • Barbosa, M.S.1    Schlegel, R.2
  • 14
    • 0026035826 scopus 로고
    • Differences in transformation activity between HPV-18 and HPV-16 map to the viral LCR-E6-E7 region
    • Villa, L. L., and Schlegel, R. Differences in transformation activity between HPV-18 and HPV-16 map to the viral LCR-E6-E7 region. Virology, 181: 374-377, 1991.
    • (1991) Virology , vol.181 , pp. 374-377
    • Villa, L.L.1    Schlegel, R.2
  • 15
    • 0024428508 scopus 로고
    • The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
    • Münger, K., Phelps, W. C., Bubb, V., Howley, P. M., and Schlegel, R. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J. Virol., 63: 4417-4421, 1989.
    • (1989) J. Virol. , vol.63 , pp. 4417-4421
    • Münger, K.1    Phelps, W.C.2    Bubb, V.3    Howley, P.M.4    Schlegel, R.5
  • 16
    • 0027745261 scopus 로고
    • Neuroepithelial carcinomas in mice transgenic with human papillomavirus type 16 E6/E7 ORFs
    • Arbeit, J. M., Münger, K., Howley, P. M., and Hanahan, D. Neuroepithelial carcinomas in mice transgenic with human papillomavirus type 16 E6/E7 ORFs. Am. J. Pathol., 142: 1187-1197, 1993.
    • (1993) Am. J. Pathol. , vol.142 , pp. 1187-1197
    • Arbeit, J.M.1    Münger, K.2    Howley, P.M.3    Hanahan, D.4
  • 17
    • 0027468114 scopus 로고
    • Tumorigenicity by human papillomavirus type 16 E6 and E7 in transgenic mice correlates with alterations in epithelial cell growth and differentiation
    • Griep, A. E., Herber, R., Jeon, S., Lohse, J. K., Dubielzig, R. R., and Lambert, P. F. Tumorigenicity by human papillomavirus type 16 E6 and E7 in transgenic mice correlates with alterations in epithelial cell growth and differentiation. J. Virol., 67, 1373-1384, 1993.
    • (1993) J. Virol. , vol.67 , pp. 1373-1384
    • Griep, A.E.1    Herber, R.2    Jeon, S.3    Lohse, J.K.4    Dubielzig, R.R.5    Lambert, P.F.6
  • 18
    • 0027211053 scopus 로고
    • Epidermal cancer associated with expression of human papillomavirus type 16 E6 and E7 oncogenes in the skin of transgenic mice
    • Lambert, P., Pan, H., Pilot, H., and et al. Epidermal cancer associated with expression of human papillomavirus type 16 E6 and E7 oncogenes in the skin of transgenic mice. Proc. Natl. Acad. Sci. USA, 90: 5583-5587, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5583-5587
    • Lambert, P.1    Pan, H.2    Pilot, H.3
  • 19
    • 0028233614 scopus 로고
    • Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice
    • Arbeit, J. M., Münger, K., Howley, P. M., and Hanahan, D. Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice. J. Virol., 68: 4358-4368. 1994.
    • (1994) J. Virol. , vol.68 , pp. 4358-4368
    • Arbeit, J.M.1    Münger, K.2    Howley, P.M.3    Hanahan, D.4
  • 20
    • 0028210058 scopus 로고
    • Stomach cancer in transgenic mice expressing human papillomavirus type 16 genes from a keratin promoter
    • Searle, P., Thomas, D., Faulkner, K., and Tinsley, J. Stomach cancer in transgenic mice expressing human papillomavirus type 16 genes from a keratin promoter. J. Gen. Virol., 75: 1125-1137, 1994.
    • (1994) J. Gen. Virol. , vol.75 , pp. 1125-1137
    • Searle, P.1    Thomas, D.2    Faulkner, K.3    Tinsley, J.4
  • 21
    • 0026000865 scopus 로고
    • Very high incidence of germ cell tumorigenesis (seminomagenesis) in human papillomavirus type 16 transgenic mice
    • Kondoh, G., Murata, Y., Aozasa, K., Yutsudo, M., and Hakura, A. Very high incidence of germ cell tumorigenesis (seminomagenesis) in human papillomavirus type 16 transgenic mice. J. Virol. 65: 3335-3339, 1991.
    • (1991) J. Virol. , vol.65 , pp. 3335-3339
    • Kondoh, G.1    Murata, Y.2    Aozasa, K.3    Yutsudo, M.4    Hakura, A.5
  • 23
    • 0035094922 scopus 로고    scopus 로고
    • Egg yolk antibodies against the E7 oncogenic protein of human papillomavirus type 16
    • Di Lonardo, A. D., Marcante, M. L., Poggiali, F., Hamsoikova, E. and Venuti, A. Egg yolk antibodies against the E7 oncogenic protein of human papillomavirus type 16. Arch. Virol., 146: 117-125, 2001.
    • (2001) Arch. Virol. , vol.146 , pp. 117-125
    • Di Lonardo, A.D.1    Marcante, M.L.2    Poggiali, F.3    Hamsoikova, E.4    Venuti, A.5
  • 25
    • 0029896941 scopus 로고    scopus 로고
    • Papillomavirus oncoproteins as vaccine candidates
    • Galloway, D. A. Papillomavirus oncoproteins as vaccine candidates. Lancet, 347: 1498-1499, 1996.
    • (1996) Lancet , vol.347 , pp. 1498-1499
    • Galloway, D.A.1
  • 26
    • 0033745220 scopus 로고    scopus 로고
    • Developing HPV virus-like particle vaccines to prevent cervical cancer: A progress report
    • Schiller, J. T., and Hidesheim, A. Developing HPV virus-like particle vaccines to prevent cervical cancer: a progress report. J. Clin. Virol., 19: 67-74, 2000.
    • (2000) J. Clin. Virol. , vol.19 , pp. 67-74
    • Schiller, J.T.1    Hidesheim, A.2
  • 27
    • 0031716454 scopus 로고    scopus 로고
    • Molecular targets for human papillomaviruses: Prospects for antiviral therapy
    • Phelps, W. C., Bames, J. A., and Lobe, D. C. Molecular targets for human papillomaviruses: prospects for antiviral therapy. Antivir. Chem. Chemother., 9: 359-377, 1998.
    • (1998) Antivir. Chem. Chemother. , vol.9 , pp. 359-377
    • Phelps, W.C.1    Bames, J.A.2    Lobe, D.C.3
  • 29
    • 0033803148 scopus 로고    scopus 로고
    • Inactivation of the human papillomavirus-16 E6 oncoprotein by organic disulfides
    • Beerheide, W., Sim, M. M., Tan, Y. J., Bernard, H. U., and Ting, A. E. Inactivation of the human papillomavirus-16 E6 oncoprotein by organic disulfides. Bioorg. Med. Chem., 8: 2549-2560. 2000.
    • (2000) Bioorg. Med. Chem. , vol.8 , pp. 2549-2560
    • Beerheide, W.1    Sim, M.M.2    Tan, Y.J.3    Bernard, H.U.4    Ting, A.E.5
  • 30
    • 0029864222 scopus 로고    scopus 로고
    • Chronic estrogen induced cervical and vaginal squamous carcinogenesis in HPV16 transgenic mice
    • Arbeit, J. M., Howley, P. M., and Hanahan, D. Chronic estrogen induced cervical and vaginal squamous carcinogenesis in HPV16 transgenic mice. Proc. Natl. Acad. Sci. USA, 93: 2930-2935, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2930-2935
    • Arbeit, J.M.1    Howley, P.M.2    Hanahan, D.3
  • 31
    • 0034163386 scopus 로고    scopus 로고
    • Sensitivity of the cervical transformation zone to estrogen-induced squamous carcinogenesis
    • Elson, D. A., Riley, R. R., Lacey, A., Thordarson, G., Talamantes, F., and Arbeit, J. M. Sensitivity of the cervical transformation zone to estrogen-induced squamous carcinogenesis. Cancer Res., 60: 1267-1275, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 1267-1275
    • Elson, D.A.1    Riley, R.R.2    Lacey, A.3    Thordarson, G.4    Talamantes, F.5    Arbeit, J.M.6
  • 32
    • 0030064068 scopus 로고    scopus 로고
    • Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene
    • Herber, R., Liem, A., Pitot, H., and Lambert, P. F. Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene. J. Virol., 70: 1873-1881, 1996.
    • (1996) J. Virol. , vol.70 , pp. 1873-1881
    • Herber, R.1    Liem, A.2    Pitot, H.3    Lambert, P.F.4
  • 33
    • 0033028610 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals
    • Song, S., Pitot, H. C., and Lambert, P. F. The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals. J. Virol., 73: 5887-5893, 1999.
    • (1999) J. Virol. , vol.73 , pp. 5887-5893
    • Song, S.1    Pitot, H.C.2    Lambert, P.F.3
  • 34
    • 0028834086 scopus 로고
    • Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization
    • Litvak, K., Flood, S., Marmato, J., Giusti, W., and Deetz, K. Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. PCR Method. Appl., 4: 357-362, 1995.
    • (1995) PCR Method. Appl. , vol.4 , pp. 357-362
    • Litvak, K.1    Flood, S.2    Marmato, J.3    Giusti, W.4    Deetz, K.5
  • 35
    • 0035476509 scopus 로고    scopus 로고
    • Induction of hypervascularity without leak or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1α
    • Elson, D. A., Thurston, G., Huang, L. E., Ginzinger, D. G., McDonald, D. M., Johnson, R. S., and Arbeit, J. M. Induction of hypervascularity without leak or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1α Genes Dev., 15: 2520-2532, 2001.
    • (2001) Genes Dev. , vol.15 , pp. 2520-2532
    • Elson, D.A.1    Thurston, G.2    Huang, L.E.3    Ginzinger, D.G.4    McDonald, D.M.5    Johnson, R.S.6    Arbeit, J.M.7
  • 37
    • 0034730196 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle
    • Duensing, S., Lee, L. Y., Duensing, A., Basile, J., Piboonniyom, S., Gonzalez, S., Crum, C. P., and Münger, K. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proc. Natl. Acad. Sci. USA, 97: 10002-10007, 2000.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10002-10007
    • Duensing, S.1    Lee, L.Y.2    Duensing, A.3    Basile, J.4    Piboonniyom, S.5    Gonzalez, S.6    Crum, C.P.7    Münger, K.8
  • 38
    • 0028334011 scopus 로고
    • Altered cell cycle regulation in the lens of HPV16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
    • Pan, H., and Griep, A. Altered cell cycle regulation in the lens of HPV16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Genes Dev., 8: 1285-1299, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 1285-1299
    • Pan, H.1    Griep, A.2
  • 39
    • 0034652546 scopus 로고    scopus 로고
    • Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis
    • Song, S., Liem, A., Miller, J. A., and Lambert, P. F. Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis. Virology, 267: 141-150, 2000.
    • (2000) Virology , vol.267 , pp. 141-150
    • Song, S.1    Liem, A.2    Miller, J.A.3    Lambert, P.F.4
  • 40
    • 0032478282 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways
    • Song, S., Gulliver, G. A., and Lambert, P. F. Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways. Proc. Natl. Acad. Sci. USA, 95, 2290-2295, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2290-2295
    • Song, S.1    Gulliver, G.A.2    Lambert, P.F.3
  • 42
    • 0001572719 scopus 로고
    • Practical points on the microscopic grading of carcinoma
    • Broders, A. Practical points on the microscopic grading of carcinoma. New York State J. Med., 32: 667-671, 1932.
    • (1932) New York State J. Med. , vol.32 , pp. 667-671
    • Broders, A.1
  • 43
    • 0030848170 scopus 로고    scopus 로고
    • Both conserved region 1 (CR1) and CR2 of the human papillomavirus type 16 E7 oncogene are required for induction of epidermal hyperplasia and tumor formation in transgenic mice
    • Gulliver, G. A., Herber, R. L., Liem, A., and Lambert, P. F. Both conserved region 1 (CR1) and CR2 of the human papillomavirus type 16 E7 oncogene are required for induction of epidermal hyperplasia and tumor formation in transgenic mice. J. Virol., 71: 5905-5914, 1997.
    • (1997) J. Virol. , vol.71 , pp. 5905-5914
    • Gulliver, G.A.1    Herber, R.L.2    Liem, A.3    Lambert, P.F.4
  • 44
    • 0030756473 scopus 로고    scopus 로고
    • The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2
    • Jones, D. L., Alani, R. M., and Münger, K. The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2. Genes Dev., 11: 2101-2111, 1997.
    • (1997) Genes Dev. , vol.11 , pp. 2101-2111
    • Jones, D.L.1    Alani, R.M.2    Münger, K.3
  • 45
    • 0025953696 scopus 로고
    • The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines
    • Scheffner, M., Münger, K., Byme, J. C., and Howley, P. M. The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc. Natl. Acad. Sci. USA, 88: 5523-5527, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5523-5527
    • Scheffner, M.1    Münger, K.2    Byme, J.C.3    Howley, P.M.4
  • 46
    • 0028243099 scopus 로고
    • Elevated wild-type p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus type 16 E7 gene
    • Demers, G. W., Halbert, C. L., and Galloway, D. A. Elevated wild-type p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus type 16 E7 gene. Virology, 198: 169-174, 1994.
    • (1994) Virology , vol.198 , pp. 169-174
    • Demers, G.W.1    Halbert, C.L.2    Galloway, D.A.3
  • 47
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.1
  • 48
    • 0032513114 scopus 로고    scopus 로고
    • The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells
    • Talis, A. L., Huibregtse, J. M., and Howley, P. M. The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells. J. Biol. Chem. 273: 6439-6445, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 6439-6445
    • Talis, A.L.1    Huibregtse, J.M.2    Howley, P.M.3
  • 49
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner, M., Huibregtse, J. M., Vierstra, R. D., and Howley, P. M. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell, 75: 495-505, 1993.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 50
    • 0028227260 scopus 로고
    • Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
    • Howes, K. A., Ransom, N., Papermaster, D. S., Lasudry, J. G., Albert, D. M., and Windle, J. J. Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes Dev., 8: 1300-1310, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 1300-1310
    • Howes, K.A.1    Ransom, N.2    Papermaster, D.S.3    Lasudry, J.G.4    Albert, D.M.5    Windle, J.J.6
  • 51
    • 0037048323 scopus 로고    scopus 로고
    • Loss of p53 and centrosome hyperamplification
    • Tarapore, P., and Fukasawa, K. Loss of p53 and centrosome hyperamplification. Oncogene, 21: 6234-6240, 2002.
    • (2002) Oncogene , vol.21 , pp. 6234-6240
    • Tarapore, P.1    Fukasawa, K.2
  • 52
    • 0037048297 scopus 로고    scopus 로고
    • Human papillomaviruses and centrosome duplication errors: Modeling the origins of genomic instability
    • Duensing, S., and Münger, K. Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability. Oncogene, 21: 6241-6248, 2002.
    • (2002) Oncogene , vol.21 , pp. 6241-6248
    • Duensing, S.1    Münger, K.2
  • 53
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D., and Weinberg, R. A. The hallmarks of cancer. Cell, 100: 57-70, 2000.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 54
    • 0028625491 scopus 로고
    • Insights from the study of animals lacking functional estrogen receptor
    • Korach, K. Insights from the study of animals lacking functional estrogen receptor. Science (Wash. DC), 266: 1524-1527, 1994.
    • (1994) Science (Wash. DC) , vol.266 , pp. 1524-1527
    • Korach, K.1
  • 55
    • 0028901194 scopus 로고
    • Tamoxifen activation of the estrogen receptor/AP-1 pathway: Potential origin for the cell-specific estrogen-like effects of antiestrogens
    • Webb, P., Lopez, G., Uht, R., and Kushner, P. Tamoxifen activation of the estrogen receptor/AP-1 pathway: Potential origin for the cell-specific estrogen-like effects of antiestrogens. Mol. Endocrinol., 9: 443-456, 1995.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 443-456
    • Webb, P.1    Lopez, G.2    Uht, R.3    Kushner, P.4
  • 56
    • 0034910012 scopus 로고    scopus 로고
    • Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes
    • Duensing, S., Duensing, A., Flores, E. R., Do, A., Lambert, P. F., and Münger, K. Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes. J. Virol., 75: 7712-7716, 2001.
    • (2001) J. Virol. , vol.75 , pp. 7712-7716
    • Duensing, S.1    Duensing, A.2    Flores, E.R.3    Do, A.4    Lambert, P.F.5    Münger, K.6
  • 57
    • 0035866774 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E7 oncoprotein-induced abnormal centrosome synthesis is an early event in the evolving malignant phenotype
    • Duensing, S., Duensing, A., Crum, C. P., and Münger, K. Human papillomavirus type 16 E7 oncoprotein-induced abnormal centrosome synthesis is an early event in the evolving malignant phenotype. Cancer Res., 61: 2356-2360, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 2356-2360
    • Duensing, S.1    Duensing, A.2    Crum, C.P.3    Münger, K.4
  • 58
    • 0025840334 scopus 로고
    • The interaction between HPV infection and estrogen metabolism in cervical carcinogenesis
    • Auborn, K., Woodworth, C., DiPaolo, J., and Bradlow, H. The interaction between HPV infection and estrogen metabolism in cervical carcinogenesis. Int. J. Cancer, 49: 867-869, 1990.
    • (1990) Int. J. Cancer , vol.49 , pp. 867-869
    • Auborn, K.1    Woodworth, C.2    DiPaolo, J.3    Bradlow, H.4
  • 59
    • 0036045456 scopus 로고    scopus 로고
    • Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: Comparison of 2- and 4-hydroxylation revisited
    • Mesia-Vela, S., Sanchez, R. I., Li, J. J., Li, S. A., Conney, A. H., and Kauffman, F. C. Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: comparison of 2- and 4-hydroxylation revisited. Carcinogenesis (Lond.), 23: 1369-1372, 2002.
    • (2002) Carcinogenesis (Lond.) , vol.23 , pp. 1369-1372
    • Mesia-Vela, S.1    Sanchez, R.I.2    Li, J.J.3    Li, S.A.4    Conney, A.H.5    Kauffman, F.C.6
  • 60
    • 0031848636 scopus 로고    scopus 로고
    • Functional role of estrogen metabolism in target cells: Review and perspectives
    • Zhu, B. T., and Conney, A. H. Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis (Lond.), 19: 1-27, 1998.
    • (1998) Carcinogenesis (Lond.) , vol.19 , pp. 1-27
    • Zhu, B.T.1    Conney, A.H.2
  • 61
    • 0028301160 scopus 로고
    • Interdependence of epidermal growth factor and insulin-like growth factor-I expression in the mouse uterus
    • Hana, V., and Murphy, L. J. Interdependence of epidermal growth factor and insulin-like growth factor-I expression in the mouse uterus. Endocrinology, 135: 107-112, 1994.
    • (1994) Endocrinology , vol.135 , pp. 107-112
    • Hana, V.1    Murphy, L.J.2
  • 62
    • 0036284244 scopus 로고    scopus 로고
    • Role of systemic and local IGF-I in the effects of estrogen on growth and epithelial proliferation of mouse uterus
    • Sato, T., Wang, G., Hardy, M. P., Kurita, T., Cunha, G. R., and Cooke, P. S. Role of systemic and local IGF-I in the effects of estrogen on growth and epithelial proliferation of mouse uterus. Endocrinology, 143: 2673-2679, 2002.
    • (2002) Endocrinology , vol.143 , pp. 2673-2679
    • Sato, T.1    Wang, G.2    Hardy, M.P.3    Kurita, T.4    Cunha, G.R.5    Cooke, P.S.6
  • 63
    • 0028927404 scopus 로고
    • Coordinate regulation by diethylstilbestrol of the platelet-derived growth factor-A (PDGF-A) and -B chains and the PDGF receptor α- and β-subunits in the mouse uterus and vagina: Potential mediators of estrogen action
    • Gray, K., Eitzman, B., Raszmann, K., Steed, T., Geboff, A., McLachlan, J., and Bidwell, M. Coordinate regulation by diethylstilbestrol of the platelet-derived growth factor-A (PDGF-A) and -B chains and the PDGF receptor α- and β-subunits in the mouse uterus and vagina: potential mediators of estrogen action. Endocrinology, 136: 2325-2340, 1995.
    • (1995) Endocrinology , vol.136 , pp. 2325-2340
    • Gray, K.1    Eitzman, B.2    Raszmann, K.3    Steed, T.4    Geboff, A.5    McLachlan, J.6    Bidwell, M.7
  • 64
    • 0028012737 scopus 로고
    • Distribution of transforming growth factor a precursors in the mouse uterus during the periimplantation period and after steroid hormone treatments
    • Paria, B. C., Das, S. K., Huet-Hudson, Y. M., and Dey, S. K. Distribution of transforming growth factor a precursors in the mouse uterus during the periimplantation period and after steroid hormone treatments. Biol. Reprod., 50: 481-491, 1994.
    • (1994) Biol. Reprod. , vol.50 , pp. 481-491
    • Paria, B.C.1    Das, S.K.2    Huet-Hudson, Y.M.3    Dey, S.K.4
  • 65
    • 0033503904 scopus 로고    scopus 로고
    • Comparison of sensitivities of uterine cells in their proliferation responding to epidermal growth factor and estrogen between neonatal and postneonatal mice
    • Kuhara, A., Tsuji, M., Tsujimura, T., Sugihara, A., Yamada, N., and Terada, N. Comparison of sensitivities of uterine cells in their proliferation responding to epidermal growth factor and estrogen between neonatal and postneonatal mice. In Vivo, 13: 487-491, 1999.
    • (1999) In Vivo , vol.13 , pp. 487-491
    • Kuhara, A.1    Tsuji, M.2    Tsujimura, T.3    Sugihara, A.4    Yamada, N.5    Terada, N.6
  • 66
    • 0028520218 scopus 로고
    • Epidermal growth factor, transforming growth factor-α, and epidermal growth factor receptor localization in the baboon (Papio anubis) uterus during the menstrual cycle and early pregnancy
    • Slowey, M. J., Verhage, H. G., and Fazleabas, A. T. Epidermal growth factor, transforming growth factor-α, and epidermal growth factor receptor localization in the baboon (Papio anubis) uterus during the menstrual cycle and early pregnancy. J. Soc. Gynecol. Investig., 1: 277-284, 1994.
    • (1994) J. Soc. Gynecol. Investig. , vol.1 , pp. 277-284
    • Slowey, M.J.1    Verhage, H.G.2    Fazleabas, A.T.3
  • 67
    • 0036060364 scopus 로고    scopus 로고
    • Inhibition of serum- and calcium-induced terminal differentiation of human keratinocytes by HPV 16 E6: Study of the association with p53 degradation, inhibition of p53 transactivation, and binding to E6BP
    • Sherman, L., Itzhaki, H., Jackman, A., Chen, J. J., Koval, D., and Schlegel, R. Inhibition of serum- and calcium-induced terminal differentiation of human keratinocytes by HPV 16 E6: study of the association with p53 degradation, inhibition of p53 transactivation, and binding to E6BP. Virology, 292: 309-320, 2002.
    • (2002) Virology , vol.292 , pp. 309-320
    • Sherman, L.1    Itzhaki, H.2    Jackman, A.3    Chen, J.J.4    Koval, D.5    Schlegel, R.6
  • 68
    • 0032816001 scopus 로고    scopus 로고
    • Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells
    • Liu, Y., Chen, J. J., Gao, Q., Dalal, S., Hong, Y., Mansur, C. P., Band, V., and Androphy, E. J. Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells. J. Virol., 73: 7297-7307, 1999.
    • (1999) J. Virol. , vol.73 , pp. 7297-7307
    • Liu, Y.1    Chen, J.J.2    Gao, Q.3    Dalal, S.4    Hong, Y.5    Mansur, C.P.6    Band, V.7    Androphy, E.J.8
  • 69
    • 0030774987 scopus 로고    scopus 로고
    • Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein
    • Kiyono, T., Hiraiwa, A., Fujita, M., Hayashi, Y., Akiyama, T., and Ishibashi, M. Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein. Proc. Natl. Acad. Sci. USA, 94: 11612-11616, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11612-11616
    • Kiyono, T.1    Hiraiwa, A.2    Fujita, M.3    Hayashi, Y.4    Akiyama, T.5    Ishibashi, M.6
  • 70
    • 0031001560 scopus 로고    scopus 로고
    • The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton
    • USA
    • Tong, X., and Howley, P. The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton. Proceedings National Academy of Sciences, USA, 94: 4412-4417, 1997.
    • (1997) Proceedings National Academy of Sciences , vol.94 , pp. 4412-4417
    • Tong, X.1    Howley, P.2
  • 71
    • 0030008177 scopus 로고    scopus 로고
    • Telomerase activation by the E6 gene product of human papillomavirus type 16
    • Klingelhutz, A. J., Foster, S. A., and McDougall, J. K. Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature (Lond.), 380: 79-82, 1996.
    • (1996) Nature (Lond.) , vol.380 , pp. 79-82
    • Klingelhutz, A.J.1    Foster, S.A.2    McDougall, J.K.3
  • 72
    • 0035043423 scopus 로고    scopus 로고
    • Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein
    • Veldman, T., Horikawa, I., Barrett, J. C., and Schlegel, R. Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein. J. Virol., 75: 4467-4472, 2001.
    • (2001) J. Virol. , vol.75 , pp. 4467-4472
    • Veldman, T.1    Horikawa, I.2    Barrett, J.C.3    Schlegel, R.4
  • 73
    • 0027200650 scopus 로고
    • The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event
    • Stoler, A., Stenback, F., and Balmain, A. The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event. J. Cell Biol., 122: 1103-1117, 1993.
    • (1993) J. Cell Biol. , vol.122 , pp. 1103-1117
    • Stoler, A.1    Stenback, F.2    Balmain, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.