Human papillomavirus type 16 E7 oncoprotein-induced abnormal centrosome synthesis is an early event in the evolving malignant phenotype

Cancer Research

Volumn 61, Issue 6, 2001, Pages 2356-2360

  Duensing, S ^a   Duensing, A ^a   Crum, C P ^a   Munger K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN;

ARTICLE; CANCER GROWTH; CELL COUNT; CENTROMERE; CENTROSOME; CHROMOSOME 11; CONTROLLED STUDY; GENETIC STABILITY; HUMAN; HUMAN CELL; MITOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WART VIRUS;

CELL NUCLEUS; CELL TRANSFORMATION, VIRAL; CENTRIOLES; CENTROSOME; HUMANS; KERATINOCYTES; ONCOGENE PROTEINS, VIRAL; OSTEOSARCOMA; PAPILLOMAVIRIDAE; PHENOTYPE; TUMOR CELLS, CULTURED;

EID: 0035866774     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Papillomavirus infections: A major cause of human cancer
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3. Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix
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5. Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins
6. Expression of HPV16 E6 or E7 increases integration of foreign DNA
7. Centrosome defects and genetic instability in malignant tumors
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9. The centrosome
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11. A transient three-plasmid expression system for the production of high titer retroviral vectors
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14. The binucleate squamous cell: Histologic spectrum and relationship to low-grade squamous intraepithelial lesions
15. γ-Tubulin is a highly conserved component of the centrosome
16. Sensitivity and specificity of various morphological features of cervical condylomas
17. 2 arrest after DNA damage