Human papillomavirus infection, centrosome aberration, and genetic stability in cervical lesions

Modern Pathology

Volumn 14, Issue 4, 2001, Pages 279-284

  Skyldberg, Barbro ^a   Fujioka, Kaoru ^a   Hellström, Ann Cathrin ^a   Sylvén, Lisskulla ^a   Moberger, Birgitta ^a   Auer, Gert ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Centrosomes; Cervical lesions; Genetic stability; HPV

Indexed keywords

CELL NUCLEUS DNA; CYCLIN A; CYCLIN E; GAMMA TUBULIN; PROTEIN P53;

ADULT; AGED; ANEUPLOIDY; ARTICLE; CARCINOGENESIS; CENTROSOME; CHROMOSOME ABERRATION; CONDYLOMA ACUMINATUM; CONTROLLED STUDY; DIPLOIDY; DNA CONTENT; DNA REPLICATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE CYTOMETRY; IMMUNOHISTOCHEMISTRY; INVASIVE CARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TETRAPLOIDY; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU; WART VIRUS;

ADULT; AGED; ANEUPLOIDY; CENTROSOME; CERVICAL INTRAEPITHELIAL NEOPLASIA; CONDYLOMATA ACUMINATA; DNA, NEOPLASM; DNA, VIRAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMAGE CYTOMETRY; MIDDLE AGED; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; POLYMERASE CHAIN REACTION; TUBULIN; TUMOR VIRUS INFECTIONS; UTERINE CERVICAL NEOPLASMS;

EID: 0035051849     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880303     Document Type: Article

References (39)

1. Abnormal centrosome amplification in the absence of p53
2. Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
3. Cell cycle control and cancer
4. Genetic instability in colorectal cancers
5. Adenocarcinoma of the uterine cervix in Ireland and Sweden: Human papillomavirus infection and biological alterations
6. Amorphous no longer: The centrosome comes into focus
7. Requirement of Cdk2-Cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts
8. Cyclin-dependent kinase control of centrosome duplication
9. Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle
10. Microtubule organizing centers
11. Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells
12. Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A
13. The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
14. The human papillomavirus E7 protein as a transforming and transactivating factor
15. Isolation of centrosomes from Spisula solidissima oocytes
16. Centro-some defects and genetic instability in malignant tumors
17. The relationship between aneuploidy and p53 overexpression during genesis of colorectal adenocarcinoma
18. Use of polymerase chain reaction amplification for the detection of human papillomaviruses
19. Implications of human papillomavirus type for survival in cervical squamous cell carcinoma
20. The use of general primers GP5 and GP6 elongated at their 3 ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR
21. Detection of HPV infection in tissue blocks by in situ hybridization as compared to a PCR procedure
22. HLA class II gene polymorphism: DNA typing, evolution, and relationship to disease susceptibility
23. Pericentrin, a highly conserved centrosome protein involved in microtubule organization
24. Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome
25. Gamma-tubulin is a component of the spindle pole body that is essential for microtubule function in Aspergillus nidulans
26. Microtubule nucleation by gamma-tubulin-containing rings in the centrosome
27. The disassembly and reassembly of functional centrosomes in vitro
28. Cold-treated centrosome: Isolation of centrosomes from mitotic sea urchin eggs, production of an anticentrosomal antibody, and novel ultrastructural imaging
29. Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer
30. Regulation of the cell cycle by viral oncoproteins
31. Distribution of aneuploid cell populations in ulcerative colitis with dysplasia or cancer
32. Genetic instabilities in human cancers
33. p53 mutations in human cancers
34. Association of human papillomavirus types 16 and 18 E6 proteins with p53
35. Papillomaviruses, p53 and cervical cancer
36. p53 mutations in cervical carcinogenesis-low frequency and lack of correlation with human papillomavirus status
37. Papillomavirus infections - A major cause of human cancers
38. Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations