The absence of p53 is critical for the induction of apoptosis by 5-aza-2′-deoxycytidine

Oncogene

Volumn 23, Issue 3, 2004, Pages 735-743

  Nieto, María ^a,b   Samper, Enrique ^a   Fraga, Mario F ^b   González De Buitrago, Gonzalo ^a   Esteller, Manel ^b   Serrano, Manuel ^a,b  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

5 aza 2 deoxycytidine; Apoptosis; Demethylation; p53

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ANTINEOPLASTIC AGENT; BREFELDIN A; CISPLATIN; DACTINOMYCIN; DOXORUBICIN; NUCLEOSIDE ANALOG; PROCAINAMIDE; PROTEIN P16; PROTEIN P19; PROTEIN P21; PROTEIN P53; S ADENOSYLHOMOCYSTEINE; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F2; ZEBULARINE;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL TRANSFORMATION; CHROMOSOME ABERRATION; DEMETHYLATION; DRUG EFFICACY; EMBRYO; FEMALE; FIBROBLAST; GENOME; MOUSE; NONHUMAN; NULL CELL; PRIORITY JOURNAL; PROTEIN DEFICIENCY; TUMOR; TUMOR CELL; WILD TYPE;

ANIMALS; APOPTOSIS; AZACITIDINE; G1 PHASE; MICE; MITOSIS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 1242272932     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207175     Document Type: Article

References (55)

1. Abad JL, Serrano F, San Roman AL, Delgado R, Bernad A and Gonzalez MA. (2002). J. Gene. Med., 4, 27-37.
2. Bernstein C, Bernstein H, Payne CM and Garewal H. (2002). Mutat. Res., 511, 145-178.
3. Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T and Hannon GJ. (1995). Nature, 377, 552-557.
4. Chen RZ, Pettersson U, Beard C, Jackson-Grusby L and Jaenisch R. (1998). Nature, 395, 89-93.
5. Cheng JC, Matsen CB, Gonzales FA, Ye W, Greer S, Marquez VE, Jones PA and Selker EU. (2003). J. Natl. Cancer Inst., 95, 399-409.
6. Christman JK. (2002). Oncogene, 21, 5483-5495.
7. De Cabo SF, Hazen MJ, Molero ML and Fernandez-Piqueras J. (1994). Experientia, 50, 658-659.
8. Eden A, Gaudet F, Waghmare A and Jaenisch R. (2003). Science, 300, 455.
9. Field SJ, Tsai FY, Kuo F, Zubiaga AM, Kaelin WG, Jr Livingston DM, Orkin SH and Greenberg ME. (1996). Cell, 85, 549-561.
10. Fraga MF, Uriol E, Borja Diego L, Berdasco M, Esteller M, Canal MJ and Rodriguez R. (2002). Electrophoresis, 23, 1677-1681.
11. Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, Leonhardt H and Jaenisch R. (2003). Science, 300, 489-492.
12. Gudkov AV and Komarova EA. (2003). Nat. Rev. Cancer, 3, 117-129.
13. Haaf T. (1995). Pharmacol. Ther., 65, 19-46.
14. Harvey M, Sands AT, Weiss RS, Hegi ME, Wiseman RW, Pantazis P, Giovanella BC, Tainsky MA, Bradley A and Donehower LA. (1993). Oncogene, 8, 2457-2467.
15. Hawkins DS, Demers GW and Galloway DA. (1996). Cancer Res., 56, 892-898.
16. Hendry JH and West CM. (1997). Int. J. Radiat. Biol., 71, 709-719.
17. Hollstein M, Sidransky D, Voselstein B and Harris CC. (1991). Science, 253, 49-53.
18. Ianzini F and Mackey MA. (1998). Mutagenesis, 13, 337-344.
19. Jacks T, Remington L, Williams BO, Schmitt EM, Halachmi S, Bronson RT and Weinberg RA. (1994). Curr. Biol., 4, 1-7.
20. Jackson-Grusby L, Beard C, Possemato R, Tudor M, Fambrough D, Csankovszki G, Dausman J, Lee P, Wilson C, Lander E and Jaenisch R. (2001). Nat. Genet., 27, 31-39.
21. Jones PA and Taylor SM. (1980). Cell, 20, 85-93.
22. Juttermann R, Li E and Jaenisch R. (1994). Proc. Natl. Acad. Sci. USA, 91, 11797-11801.
23. Kamijo T, Zindy F, Roussel MF, Quelle DE, Downing JR, Ashmun RA, Grosveld G and Sherr CJ. (1997). Cell, 91, 649-659.
24. Karpf AR, Moore BC, Ririe TO and Jones DA. (2001). Mol. Pharmacol., 59, 751-757.
25. Kuerbitz SJ, Plunkett BS, Walsh WV and Kastan MB. (1992). Proc. Natl. Acad. Sci. USA, 89, 7491-7495.
26. Lackinger D and Kaina B. (2000). Mutat. Res., 457, 113-123.
27. Lanza F and Bi S. (1995). Stem Cells, 13, 445-452.
28. Lee JM and Bernstein A. (1993). Proc. Natl. Acad. Sci. USA, 90, 5742-5746.
29. Lin X, Asgari K, Putzi MJ, Gage WR, Yu X, Cornblatt BS, Kumar A, Piantadosi S, DeWeese TL, De Marzo AM and Nelson WG. (2001). Cancer Res., 61, 8611-8616.
30. Lin Y, Waldman BC and Waldman AS. (2003). DNA Repair (Amst.), 2, 1-11.
31. Lips J and Kaina B. (2001). Carcinogenesis, 22, 579-585.
32. Lowe SW, Ruley HE, Jacks T and Housman DE. (1993). Cell, 74, 957-967.
33. McKay BC, Becerril C and Ljungman M. (2001). Oncogene, 20, 6805-6808.
34. Mori N, Hidai H, Yokota J, Okada M, Motoji T, Oshimi K and Mizoguchi H. (1995). Leuk. Res., 19, 869-875.
35. Murga M, Fernandez-Capetillo O, Field SJ, Moreno B, Borlado LR, Fujiwara Y, Balomenos D, Vicario A, Carrera AC, Orkin SH, Greenberg ME and Zubiaga AM. (2001). Immunity, 15, 959-970.
36. Palmero I, Pantoja C and Serrano M. (1998). Nature, 395, 125-126.
37. Palmero I and Serrano M. (2001). Methods Enzymol., 333, 247-256.
38. Paz MF, Fraga MF, Avila S, Guo M, Pollan M, Herman JG and Esteller M. (2003). Cancer Res., 63, 1114-1121.
39. Peller S. (1998). Semin. Cancer Biol., 8, 379-387.
40. Plumb JA, Strathdee G, Sludden J, Kaye SB and Brown R. (2000). Cancer Res., 60, 6039-6044.
41. Purdie CA, Harrison DJ, Peter A, Dobbie L, White S, Howie SE, Salter DM, Bird CC, Wyllie AH, Hooper ML and Clarke AR. (1994). Oncogene, 9, 603-609.
42. Roninson IB, Broude EV and Chang BD. (2001). Drug Resist. Update, 4, 303-313.
43. Ruiz-Vela A, Gonzalez de Buitrago G and Martinez AC. (2002). FEBS Lett., 517, 133-138.
44. Santini V, Kantarjian HM and Issa JP. (2001). Ann. Intern. Med., 134, 573-586.
45. Scheinbart LS, Johnson MA, Gross LA, Edelstein SR and Richardson BC. (1991). J. Rheumatol., 18, 530-534.
46. Serrano M, Lee H, Chin L, Cordon-Cardo C, Beach D and DePinho RA. (1996). Cell, 85, 27-37.
47. Serrano M, Lin AW, McCurrach ME, Beach D and Lowe SW. (1997). Cell, 88, 593-602.
48. Smith ML, Ford JM, Hollander MC, Bortnick RA, Amundson SA, Seo YR, Deng CX, Hanawalt PC and Fornace Jr AJ. (2000). Mol. Cell. Biol., 20, 3705-3714.
49. Stancheva I, Hensey C and Meehan RR. (2001). EMBO J., 20, 1963-1973.
50. Stuppia L, Calabrese G, Peila R, Guanciali-Franchi P, Morizio E, Spadano A and Palka G. (1997). Cancer Genet. Cytogenet., 98, 28-35.
51. Tang JL, Tien HF, Lin MT, Chen PJ and Chen YC. (1998). Anticancer Res., 18, 3757-3761.
52. Ueland PM. (1982). Pharmacol. Rev., 34, 223-253.
53. van Groeningen CJ, Leyva A, O'Brien AM, Gall HE and Pinedo HM. (1986). Cancer Res., 46, 4831-4836.
54. Weller M. (1998). Cell Tissue Res., 292, 435-445.
55. Zuber J, Tchernitsa OI, Hinzmann B, Schmitz AC, Grips M, Hellriegel M, Sers C, Rosenthal A and Schafer R. (2000). Nat. Genet., 24, 144-152.