-
1
-
-
0027109075
-
p53, guardian of the genome
-
1. Lane D (1992) p53, guardian of the genome. Nature 358:15-16
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.1
-
2
-
-
0018348655
-
T antigens bound to a host protein in SV40 transformed cells
-
2. Lane D, Crawford LV (1979) T antigens bound to a host protein in SV40 transformed cells. Nature 278:261-263
-
(1979)
Nature
, vol.278
, pp. 261-263
-
-
Lane, D.1
Crawford, L.V.2
-
3
-
-
0018760324
-
Characterization of a 54000 MW cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
-
3. Linzer DIH, Levine AJ (1979) Characterization of a 54000 MW cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell 17:43-52
-
(1979)
Cell
, vol.17
, pp. 43-52
-
-
Linzer, D.I.H.1
Levine, A.J.2
-
4
-
-
0025375355
-
Structural aspects of the p53 protein in relation to gene evolution
-
4. Soussi T, Caron de Fromental C, May P (1990) Structural aspects of the p53 protein in relation to gene evolution. Oncogene 5:945-952
-
(1990)
Oncogene
, vol.5
, pp. 945-952
-
-
Soussi, T.1
Caron De Fromental, C.2
May, P.3
-
5
-
-
0026849821
-
Definition of a consensus binding site for p53
-
5. El-Deiry WS, Kern SE, Pietenpol JA, Kinzlier KW, Vogelstein B (1992) Definition of a consensus binding site for p53. Nature Genet 1:45-49
-
(1992)
Nature Genet
, vol.1
, pp. 45-49
-
-
El-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzlier, K.W.4
Vogelstein, B.5
-
6
-
-
0029845760
-
Structure and function of the p53 tumor suppressor gene: Clues for rational cancer therapeutic strategies
-
6. Harris CC (1996) Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategies. J Natl Cancer Inst 88:1442-1455
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1442-1455
-
-
Harris, C.C.1
-
7
-
-
0025024469
-
Presence of a potent transcription activating sequence in the p53 protein
-
7. Fields S, Jang SK (1990) Presence of a potent transcription activating sequence in the p53 protein. Science 249:1046-1048
-
(1990)
Science
, vol.249
, pp. 1046-1048
-
-
Fields, S.1
Jang, S.K.2
-
8
-
-
0028952841
-
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms
-
8. Jeffrey PD, Gorina S, Pavletich NP (1995) Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms. Science 267:1498-1502
-
(1995)
Science
, vol.267
, pp. 1498-1502
-
-
Jeffrey, P.D.1
Gorina, S.2
Pavletich, N.P.3
-
9
-
-
0025201181
-
Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis
-
9. Shaulsky G, Goldfinger N, Benzeev A, Rotter V (1990) Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis. Mol Cell Biol 10:6565-6577
-
(1990)
Mol Cell Biol
, vol.10
, pp. 6565-6577
-
-
Shaulsky, G.1
Goldfinger, N.2
Benzeev, A.3
Rotter, V.4
-
10
-
-
0028862982
-
The c-terminal domain of p53 recognizes DNA damaged by ionizing radiation
-
10. Reed M, Woelker B, Wang P, Wang Y, Anderson ME, Tegtmeyer P (1995) The c-terminal domain of p53 recognizes DNA damaged by ionizing radiation. Proc Natl Acad Sci USA 92:9455-9459
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9455-9459
-
-
Reed, M.1
Woelker, B.2
Wang, P.3
Wang, Y.4
Anderson, M.E.5
Tegtmeyer, P.6
-
11
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
11. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW (1991) Participation of p53 protein in the cellular response to DNA damage. Cancer Res 51:6304-6311
-
(1991)
Cancer Res
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
12
-
-
0028813528
-
Evidence for a second cell cycle block at G2/M by p53
-
12. Stewart N, Hicks GG, Paraskevas F, Mowat M (1995) Evidence for a second cell cycle block at G2/M by p53. Oncogene 10:109-115
-
(1995)
Oncogene
, vol.10
, pp. 109-115
-
-
Stewart, N.1
Hicks, G.G.2
Paraskevas, F.3
Mowat, M.4
-
13
-
-
0030700333
-
Role of wild type p53 in the G2 phase: Regulation of the γ-irradiation induced delay and DNA repair
-
13. Schwartz D, Almog N, Peled A, Goldfinger N, Rotter V (1997) Role of wild type p53 in the G2 phase: regulation of the γ-irradiation induced delay and DNA repair. Oncogene 15:2597-2607
-
(1997)
Oncogene
, vol.15
, pp. 2597-2607
-
-
Schwartz, D.1
Almog, N.2
Peled, A.3
Goldfinger, N.4
Rotter, V.5
-
14
-
-
0025784539
-
Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6
-
14. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M (1991) Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6. Nature 352:345-347
-
(1991)
Nature
, vol.352
, pp. 345-347
-
-
Yonish-Rouach, E.1
Resnitzky, D.2
Lotem, J.3
Sachs, L.4
Kimchi, A.5
Oren, M.6
-
15
-
-
0027983669
-
Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
-
15. Cho Y, Gorina S, Jeffrey PD, Pavletich NP (1994) Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science 265:346-355
-
(1994)
Science
, vol.265
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
16
-
-
0030564943
-
Structural aspects of the p53 protein in relation to gene evolution: A second look
-
16. Soussi T, May P (1996) Structural aspects of the p53 protein in relation to gene evolution: a second look. J Mol Biol 260:623-637
-
(1996)
J Mol Biol
, vol.260
, pp. 623-637
-
-
Soussi, T.1
May, P.2
-
17
-
-
0030752030
-
Database of p53 somatic mutations in human tumors and cell lines: Updated compilation and future prospects
-
17. Hainaut P, Soussi T, Shomer B, Hollstein M, Greenblatt M, Hovig E, Harris CC, Montesano R (1997) Database of p53 somatic mutations in human tumors and cell lines: updated compilation and future prospects. Nucleic Acid Res 25:151-157
-
(1997)
Nucleic Acid Res
, vol.25
, pp. 151-157
-
-
Hainaut, P.1
Soussi, T.2
Shomer, B.3
Hollstein, M.4
Greenblatt, M.5
Hovig, E.6
Harris, C.C.7
Montesano, R.8
-
18
-
-
0030043019
-
The 1995 Walter Hubert lecture - Molecular epidemiology of human cancer: Insights from the mutational analysis of the p53 tumor-suppressor gene
-
18. Harris CC (1996) The 1995 Walter Hubert Lecture - molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumor-suppressor gene. Br J Cancer 73:261-269
-
(1996)
Br J Cancer
, vol.73
, pp. 261-269
-
-
Harris, C.C.1
-
19
-
-
0028353711
-
Multifactorial analysis of p53 alteration in human cancer: A review
-
19. Soussi T, Legros Y, Lubin R, Ory K, Schlichtholz B (1994) Multifactorial analysis of p53 alteration in human cancer: a review. Int J Cancer 57:1-9
-
(1994)
Int J Cancer
, vol.57
, pp. 1-9
-
-
Soussi, T.1
Legros, Y.2
Lubin, R.3
Ory, K.4
Schlichtholz, B.5
-
20
-
-
0026724877
-
Accumulation of p53 tumor suppressor gene protein: An independent marker of prognosis in breast cancers
-
20. Thor AD, Moore DH, Edgerton SM et al (1992) Accumulation of p53 tumor suppressor gene protein: an independent marker of prognosis in breast cancers. J Natl Cancer Inst 84:845-855
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 845-855
-
-
Thor, A.D.1
Moore, D.H.2
Edgerton, S.M.3
-
21
-
-
0029084995
-
TP53 mutations and breast cancer prognosis: Particularly poor survival rates for cases with mutations in the zinc-binding domains
-
21. Borresen A-L, Andersen TI, Eyfjord JE, Cornelis RS, Thoracius S et al (1995) TP53 mutations and breast cancer prognosis: particularly poor survival rates for cases with mutations in the zinc-binding domains. Gene Chromos Cancer 14:71-75
-
(1995)
Gene Chromos Cancer
, vol.14
, pp. 71-75
-
-
Borresen, A.-L.1
Andersen, T.I.2
Eyfjord, J.E.3
Cornelis, R.S.4
Thoracius, S.5
-
22
-
-
1842338680
-
Conserved region mutations of the p53 gene are concentrated in distal colorectal cancers
-
22. Jervall P, Makinen M, Kattunen T, Makela J, Vihko P (1997) Conserved region mutations of the p53 gene are concentrated in distal colorectal cancers. Int J Cancer 74:97-101
-
(1997)
Int J Cancer
, vol.74
, pp. 97-101
-
-
Jervall, P.1
Makinen, M.2
Kattunen, T.3
Makela, J.4
Vihko, P.5
-
23
-
-
0030894182
-
K-ras and p53 mutations are an independent unfavourable prognostic indicator in patients with non-small-cell lung cancer
-
23. Fukuyama Y, Mitsudomi T, Sugio K, Ishida T, Akazawa K, Sugimachi K (1997) K-ras and p53 mutations are an independent unfavourable prognostic indicator in patients with non-small-cell lung cancer. Br J Cancer 75:1125-1130
-
(1997)
Br J Cancer
, vol.75
, pp. 1125-1130
-
-
Fukuyama, Y.1
Mitsudomi, T.2
Sugio, K.3
Ishida, T.4
Akazawa, K.5
Sugimachi, K.6
-
24
-
-
0031266344
-
Molecular heterogeneity in prostate cancer: Can TP53 mutation unravel tumorigenesis?
-
24. Roy-Burman P, Zheng J, Miller GJ (1997) Molecular heterogeneity in prostate cancer: can TP53 mutation unravel tumorigenesis? Mol Med Today 476-482
-
(1997)
Mol Med Today
, pp. 476-482
-
-
Roy-Burman, P.1
Zheng, J.2
Miller, G.J.3
-
25
-
-
0031029907
-
p53 abnormalities in primary prostate cancer: Single-strand conformation polymorphism analysis of complementary DNA in comparison with genomic DNA
-
25. Gumerlock PH, Chi S-G, Shi X-B, Voeller HJ, Jacobson JW, Gelman EP, White RW, DeVere (1997) p53 abnormalities in primary prostate cancer: single-strand conformation polymorphism analysis of complementary DNA in comparison with genomic DNA. J Natl Cancer Inst 89:66-71
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 66-71
-
-
Gumerlock, P.H.1
Chi, S.-G.2
Shi, X.-B.3
Voeller, H.J.4
Jacobson, J.W.5
Gelman, E.P.6
White, R.W.7
DeVere8
-
26
-
-
0031799893
-
High prevalence of codon 213 (arg → stop) mutations of the TP53 gene in human ovarian cancer in the southwestern part of the Netherlands
-
26. Shuyer M, HenzelLogmans SC, vqanderBurg MEL, Fieret EJH, Kijin JGM, Foekens JA, Berns EMJJ (1998) High prevalence of codon 213 (arg → stop) mutations of the TP53 gene in human ovarian cancer in the southwestern part of The Netherlands. Int J Cancer 76:299-303
-
(1998)
Int J Cancer
, vol.76
, pp. 299-303
-
-
Shuyer, M.1
HenzelLogmans, S.C.2
VqanderBurg, M.E.L.3
Fieret, E.J.H.4
Kijin, J.G.M.5
Foekens, J.A.6
Berns, E.M.J.J.7
-
27
-
-
0027999617
-
Structure and function of p53 in normal cells and their abberations in cancer cells: Projection on the hematologic cell lineage
-
27. Prokocimer M, Rotter V (1994) Structure and function of p53 in normal cells and their abberations in cancer cells: projection on the hematologic cell lineage. Blood 84:2391-2411
-
(1994)
Blood
, vol.84
, pp. 2391-2411
-
-
Prokocimer, M.1
Rotter, V.2
-
28
-
-
0030987513
-
The clinical significance of mutations of the p53 tumor suppressor gene in haematological malignancies
-
28. Preudhomme C, Fenaux P (1997) The clinical significance of mutations of the p53 tumor suppressor gene in haematological malignancies. Br J Haematol 98:502-511
-
(1997)
Br J Haematol
, vol.98
, pp. 502-511
-
-
Preudhomme, C.1
Fenaux, P.2
-
29
-
-
0030818785
-
Mutations of the p53 gene as a prognostic factor in aggressive B-cell lymphoma
-
29. Ichkawa A, Kinoshita T, Watanabe T et al (1997) Mutations of the p53 gene as a prognostic factor in aggressive B-cell lymphoma. N Engl J Med 337:529-534
-
(1997)
N Engl J Med
, vol.337
, pp. 529-534
-
-
Ichkawa, A.1
Kinoshita, T.2
Watanabe, T.3
-
30
-
-
0031974751
-
Molecular alteration in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia
-
30. Peller S, Yona R, Kopilova Y, Prokocimer M et al (1998) Molecular alteration in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia. Gene Chrom Cancer 21:2-7
-
(1998)
Gene Chrom Cancer
, vol.21
, pp. 2-7
-
-
Peller, S.1
Yona, R.2
Kopilova, Y.3
Prokocimer, M.4
-
31
-
-
0026694826
-
Two distinct mechanisms alter p53 in breast cancer: Mutations and nuclear exclusion
-
31. Moll UM, Riou G, Levine AJ (1992) Two distinct mechanisms alter p53 in breast cancer: mutations and nuclear exclusion. Proc Natl Acad Sci USA 89:7262-7266
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7262-7266
-
-
Moll, U.M.1
Riou, G.2
Levine, A.J.3
-
32
-
-
0026632997
-
Abnormal expression of wild type p53 in normal cells of a cancer family patient
-
32. Barnes DM, Hanby AM, Gillett CE et al (1992) Abnormal expression of wild type p53 in normal cells of a cancer family patient. Lancet 340:259-263
-
(1992)
Lancet
, vol.340
, pp. 259-263
-
-
Barnes, D.M.1
Hanby, A.M.2
Gillett, C.E.3
-
33
-
-
0028044789
-
Heterogeneity of subcellular localization of p53 protein in human glioblastomas
-
33. Ali IU, Schweitzer JB, Ikejiri B, Saxena A, Robertson JT, Olsfield EH (1994) Heterogeneity of subcellular localization of p53 protein in human glioblastomas. Cancer Res 54:1-5
-
(1994)
Cancer Res
, vol.54
, pp. 1-5
-
-
Ali, I.U.1
Schweitzer, J.B.2
Ikejiri, B.3
Saxena, A.4
Robertson, J.T.5
Olsfield, E.H.6
-
34
-
-
0029049828
-
Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastoma but not in differentiated tumors
-
34. Moll UM, LaGuaglia MB, Riou G (1995) Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastoma but not in differentiated tumors. Proc Natl Acad Sci USA 92:4407-4411
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4407-4411
-
-
Moll, U.M.1
LaGuaglia, M.B.2
Riou, G.3
-
35
-
-
0028286988
-
Cytoplasmic accumulation of p53 protein, an independent prognostic indicator in colorectal adenocarcinomas
-
35. Bosari S, Viale G, Bossi P, Maggioni M, Coggi G, Murray JJ, Lee AKC (1994) Cytoplasmic accumulation of p53 protein, an independent prognostic indicator in colorectal adenocarcinomas. J Natl Cancer Inst 86:681-687
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 681-687
-
-
Bosari, S.1
Viale, G.2
Bossi, P.3
Maggioni, M.4
Coggi, G.5
Murray, J.J.6
Lee, A.K.C.7
-
37
-
-
0030048389
-
Cytoplasmic sequestration of wild-type p53 protein impairs the G1 check point after DNA damage
-
37. Moll UM, Ostermeyer AG, Haladay R, Winkfield B, Frazier M, Zambetti G (1996) Cytoplasmic sequestration of wild-type p53 protein impairs the G1 check point after DNA damage. Mol Cell Biol 16:1126-1137
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1126-1137
-
-
Moll, U.M.1
Ostermeyer, A.G.2
Haladay, R.3
Winkfield, B.4
Frazier, M.5
Zambetti, G.6
-
38
-
-
15444344269
-
Bcl-2 inhibits nuclear import following DNA damage
-
38. Beham A, Marin MC, Fernandez A, Herrmann J, Brisbay S, Tari AM, LopezBernstein G, Lozano G, Sarkiss M, McDonnell TJ (1997) Bcl-2 inhibits nuclear import following DNA damage. Oncogene 15:2767-2772
-
(1997)
Oncogene
, vol.15
, pp. 2767-2772
-
-
Beham, A.1
Marin, M.C.2
Fernandez, A.3
Herrmann, J.4
Brisbay, S.5
Tari, A.M.6
LopezBernstein, G.7
Lozano, G.8
Sarkiss, M.9
McDonnell, T.J.10
-
39
-
-
0030696170
-
Cytoplasmic retention of the p53 tumor suppressor gene product is observed in the hepatitis B virus X gene-transfected cells
-
39. Takada S, Kaneniwa N, Tsuchida N, Koike K (1997) Cytoplasmic retention of the p53 tumor suppressor gene product is observed in the hepatitis B virus X gene-transfected cells. Oncogene 15:1895-1901
-
(1997)
Oncogene
, vol.15
, pp. 1895-1901
-
-
Takada, S.1
Kaneniwa, N.2
Tsuchida, N.3
Koike, K.4
-
40
-
-
0031460372
-
Hepatitis B virus X 1 protein and tumor suppressor interactions in the modulation of apoptosis
-
40. Elmore LW, Hancock AR, Chang SF et al (1997) Hepatitis B virus X 1 protein and tumor suppressor interactions in the modulation of apoptosis. Proc Natl Acad Sci USA 94:14707-14712
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14707-14712
-
-
Elmore, L.W.1
Hancock, A.R.2
Chang, S.F.3
-
41
-
-
0026649648
-
The mdm2 oncogene product forms a complex with the p53 protein and inhibits p53 mediated transactivation
-
41. Momand J, Zambetti GP, Olson DC, Goerge D, Levine AJ (1992) The mdm2 oncogene product forms a complex with the p53 protein and inhibits p53 mediated transactivation. Cell 69:1237-1245
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
Goerge, D.4
Levine, A.J.5
-
42
-
-
0027359827
-
WAF1 a potential mediator of p53 tumor suppression
-
42. El-Deiry WS, Tokino T, Velulesco VE, Levy DB, Parsons R, Trent JM et al (1993) WAF1 a potential mediator of p53 tumor suppression. Cell 73:817-825
-
(1993)
Cell
, vol.73
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velulesco, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
-
43
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
43. Miyashita T, Reed JC (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
44
-
-
0029899837
-
Oddball p53 in testicular tumors
-
44. Chresta CM, Hickman JA (1996) Oddball p53 in testicular tumors. Nature Med 2:745-746
-
(1996)
Nature Med
, vol.2
, pp. 745-746
-
-
Chresta, C.M.1
Hickman, J.A.2
-
45
-
-
0029944241
-
A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation
-
45. Lutzker SG, Levine AJ (1996) A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation. Nature Med 2:804-810
-
(1996)
Nature Med
, vol.2
, pp. 804-810
-
-
Lutzker, S.G.1
Levine, A.J.2
-
46
-
-
0023032404
-
The molecular basis for heterogeneity of the human p53 protein
-
46. Harris N, Brill E, Shohat O, Prokocimer M, Wolf D, Arai N, Rotter V (1986) The molecular basis for heterogeneity of the human p53 protein. Mol Cell Biol 6:4650-4656
-
(1986)
Mol Cell Biol
, vol.6
, pp. 4650-4656
-
-
Harris, N.1
Brill, E.2
Shohat, O.3
Prokocimer, M.4
Wolf, D.5
Arai, N.6
Rotter, V.7
-
47
-
-
0029968463
-
Analysis of a germ line polymorphism of the p53 gene in lung cancer patients, discrete results with smoking history
-
47. Murata M, Tagawa M, Kimura H, Watanabe S, Saiaho H (1996) Analysis of a germ line polymorphism of the p53 gene in lung cancer patients, discrete results with smoking history. Carcinogenesis 17:261-264
-
(1996)
Carcinogenesis
, vol.17
, pp. 261-264
-
-
Murata, M.1
Tagawa, M.2
Kimura, H.3
Watanabe, S.4
Saiaho, H.5
-
48
-
-
0029620615
-
A novel polymorphism in intron 6 of the human p53 gene: A possible association with cancer predisposition and susceptibility
-
48. Peller S, Kopilova Y, Slutzki S, Halevy A, Kvitko K, Rotter V (1995) A novel polymorphism in intron 6 of the human p53 gene: a possible association with cancer predisposition and susceptibility. DNA Cell Biol 14:983-990
-
(1995)
DNA Cell Biol
, vol.14
, pp. 983-990
-
-
Peller, S.1
Kopilova, Y.2
Slutzki, S.3
Halevy, A.4
Kvitko, K.5
Rotter, V.6
-
49
-
-
7144250518
-
Role of a p53 polymorphism in the human papilloma-virus-associated cancer
-
49. Storey A, Thomas M, Kalita A, Harwood C et al (1998) Role of a p53 polymorphism in the human papilloma-virus-associated cancer. Nature 393:229-234
-
(1998)
Nature
, vol.393
, pp. 229-234
-
-
Storey, A.1
Thomas, M.2
Kalita, A.3
Harwood, C.4
-
50
-
-
0031418564
-
Silent and multiple mutations in p53 and the question of the hypermutability of tumors
-
50. Strauss BS (1997) Silent and multiple mutations in p53 and the question of the hypermutability of tumors. Carcinogenesis 18:1445-1452
-
(1997)
Carcinogenesis
, vol.18
, pp. 1445-1452
-
-
Strauss, B.S.1
-
51
-
-
0030221787
-
The humoral response to the tumor suppressor gene-product p53 in human cancer: Implications for diagnosis and therapy
-
51. Soussi T (1996) The humoral response to the tumor suppressor gene-product p53 in human cancer: implications for diagnosis and therapy. Immunol Today 17:354-356
-
(1996)
Immunol Today
, vol.17
, pp. 354-356
-
-
Soussi, T.1
-
52
-
-
0030789994
-
Serum anti-p53 antibodies in patients with squamous cell carcinoma of the esophagus: Comparison with p53 alterations and lymph node invasion
-
52. Collet B, Raoul JL, LeBerre N, Hersbach D, Meritte H, Quillien V, DeCertaines JD (1997) Serum anti-p53 antibodies in patients with squamous cell carcinoma of the esophagus: comparison with p53 alterations and lymph node invasion. Inter J Oncol 11:617-621
-
(1997)
Inter J Oncol
, vol.11
, pp. 617-621
-
-
Collet, B.1
Raoul, J.L.2
LeBerre, N.3
Hersbach, D.4
Meritte, H.5
Quillien, V.6
DeCertaines, J.D.7
-
53
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
53. Malkin D, Li FP, Strong LC, Fraumeni JFJ et al (1990) Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni, J.F.J.4
-
54
-
-
0029558570
-
Germline mutations in the TP53 gene
-
54. Eeles RA (1995) Germline mutations in the TP53 gene. Cancer Surv 25:101-124
-
(1995)
Cancer Surv
, vol.25
, pp. 101-124
-
-
Eeles, R.A.1
-
55
-
-
0030957152
-
Li-Fraumeni syndrome - A molecular and clinical review
-
55. Varley JM, Evans Dgr, Birch JM (1997) Li-Fraumeni syndrome - a molecular and clinical review. Br J Cancer 76:1-14
-
(1997)
Br J Cancer
, vol.76
, pp. 1-14
-
-
Varley, J.M.1
Evans, Dgr.2
Birch, J.M.3
-
56
-
-
0032077330
-
A novel germ-line mutation in the noncoding region of the p53 gene in a Li-Fraumeni family
-
56. Barel D, Avigad S, Mor C, Fogel M, Cohen IJ, Zaizov R (1998) A novel germ-line mutation in the noncoding region of the p53 gene in a Li-Fraumeni family. Cancer Genet Cytogenet 103:1-6
-
(1998)
Cancer Genet Cytogenet
, vol.103
, pp. 1-6
-
-
Barel, D.1
Avigad, S.2
Mor, C.3
Fogel, M.4
Cohen, I.J.5
Zaizov, R.6
-
57
-
-
0026480293
-
Cancer risks from germline p53 mutations
-
57. Frebourg T, Friend SH (1992) Cancer risks from germline p53 mutations. J Clin Invest 90:1637-1641
-
(1992)
J Clin Invest
, vol.90
, pp. 1637-1641
-
-
Frebourg, T.1
Friend, S.H.2
-
58
-
-
0026658152
-
Absence of hereditary p53 mutations in 10 familial leukemia pedigrees
-
58. Felix CA, D'Amico D, Mitsudomi T et al (1992) Absence of hereditary p53 mutations in 10 familial leukemia pedigrees. J Clin Invest 96:653-658
-
(1992)
J Clin Invest
, vol.96
, pp. 653-658
-
-
Felix, C.A.1
D'Amico, D.2
Mitsudomi, T.3
-
59
-
-
0026082886
-
Mutations in p53 do not account for heritable breast cancer: A study in five affected families
-
59. Prosser J, Elder PA, Condie A, MacFadyen I, Steel CM, Evans HJ (1991) Mutations in p53 do not account for heritable breast cancer: a study in five affected families. Br J Cancer 63:181-184
-
(1991)
Br J Cancer
, vol.63
, pp. 181-184
-
-
Prosser, J.1
Elder, P.A.2
Condie, A.3
MacFadyen, I.4
Steel, C.M.5
Evans, H.J.6
-
60
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
60. Levine AJ (1997) p53, the cellular gatekeeper for growth and division. Cell 88:323-331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
61
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
61. Fearon ER, Vogelstein B (1990) A genetic model for colorectal tumorigenesis. Cell 61:759-767
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
62
-
-
0029826170
-
p53 tumor suppressor gene status and the degree of genomic instability in sporadic colorectal cancers
-
62. Kahlenberg MS, Stoler DL, Basik M, Petrelli NJ, Rodrigues-Bigas M, Anderson GR (1996) p53 tumor suppressor gene status and the degree of genomic instability in sporadic colorectal cancers. J Natl Cancer Inst 88:1665-1670
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1665-1670
-
-
Kahlenberg, M.S.1
Stoler, D.L.2
Basik, M.3
Petrelli, N.J.4
Rodrigues-Bigas, M.5
Anderson, G.R.6
-
63
-
-
0030025772
-
Life (and death) in a malignant tumour
-
63. Kinzler KW, Vogelstein B (1996) Life (and death) in a malignant tumour. Nature 379:19-20
-
(1996)
Nature
, vol.379
, pp. 19-20
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
64
-
-
0030772811
-
Widely dispersed p53 mutation in respiratory epithelium
-
64. Fanklin WA, Gazdar AF, Haney J et al (1997) Widely dispersed p53 mutation in respiratory epithelium. J Clin Invest 100:2133-2137
-
(1997)
J Clin Invest
, vol.100
, pp. 2133-2137
-
-
Fanklin, W.A.1
Gazdar, A.F.2
Haney, J.3
-
65
-
-
0030905316
-
Loss of the tumor suppressor p53 gene at the liver cirrhosis stage in Japanese patients with hepatocellular carcinoma
-
65. Kishimoto Y, Shiota G, Kamisaki Y et al (1997) Loss of the tumor suppressor p53 gene at the liver cirrhosis stage in Japanese patients with hepatocellular carcinoma. Oncology 54:304-310
-
(1997)
Oncology
, vol.54
, pp. 304-310
-
-
Kishimoto, Y.1
Shiota, G.2
Kamisaki, Y.3
-
66
-
-
0030790238
-
Differential effects of p53 mutations on the growth of human bronchial epithelial cells
-
66. Coursen JD, Bennet WP, Khan MA, Forrester K, Pietenpol JA, Harris CC (1997) Differential effects of p53 mutations on the growth of human bronchial epithelial cells. Mol Carcinogen 19:191-203
-
(1997)
Mol Carcinogen
, vol.19
, pp. 191-203
-
-
Coursen, J.D.1
Bennet, W.P.2
Khan, M.A.3
Forrester, K.4
Pietenpol, J.A.5
Harris, C.C.6
-
67
-
-
0030884437
-
The effect of different TP53 mutations on the chromosomal stability of a human colonie adenoma derived cell line with endogenous wild type TP53 activity, before and after DNA damage
-
67. Williams AC, Miller JC, Collard T, Browne SJ, Newbold RF, Paraskeva C (1997) The effect of different TP53 mutations on the chromosomal stability of a human colonie adenoma derived cell line with endogenous wild type TP53 activity, before and after DNA damage. Gene Chromos Cancer 20:44-52
-
(1997)
Gene Chromos Cancer
, vol.20
, pp. 44-52
-
-
Williams, A.C.1
Miller, J.C.2
Collard, T.3
Browne, S.J.4
Newbold, R.F.5
Paraskeva, C.6
-
68
-
-
0031431667
-
Differences in the p53 gene mutational spectra of prostate cancers between Japan and Western countries
-
68. Watanabe M, Fukutome K, Shiraishi T et al (1997) Differences in the p53 gene mutational spectra of prostate cancers between Japan and Western countries. Carcinogenesis 18:1355-1358
-
(1997)
Carcinogenesis
, vol.18
, pp. 1355-1358
-
-
Watanabe, M.1
Fukutome, K.2
Shiraishi, T.3
-
69
-
-
0031815216
-
The influence of cell context on the selection pressure for p53 mutation in human cancer
-
69. Wynford-Thomas D, Blaydes J (1998) The influence of cell context on the selection pressure for p53 mutation in human cancer. Carcinogenesis 19:29-36
-
(1998)
Carcinogenesis
, vol.19
, pp. 29-36
-
-
Wynford-Thomas, D.1
Blaydes, J.2
-
70
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
70. Lowe SW, Ruley HE, Jacks T, Housman DE (1993) p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957-967
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
72
-
-
0030930366
-
A model for p53-induced apoptosis
-
72. Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B (1997) A model for p53-induced apoptosis. Nature 389:300-305
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
73
-
-
0031253967
-
On the TRAIL from p53 to apoptosis?
-
73. Kastan M (1997) On the TRAIL from p53 to apoptosis? Nature Genet 17:130-131
-
(1997)
Nature Genet
, vol.17
, pp. 130-131
-
-
Kastan, M.1
-
74
-
-
0030667522
-
Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways
-
74. Barlow C, Brown KD, Deng C-X, Tagle DA, Wynshaw-Boris A (1997) Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways. Nature Genet 17:453-456
-
(1997)
Nature Genet
, vol.17
, pp. 453-456
-
-
Barlow, C.1
Brown, K.D.2
Deng, C.-X.3
Tagle, D.A.4
Wynshaw-Boris, A.5
-
75
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
75. Lowe SW, Bodis S, McClatchey A et al (1994) p53 status and the efficacy of cancer therapy in vivo. Science 266:807-810
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
-
76
-
-
0030903281
-
Role of p53 in drug resistance in ovarian cancer
-
76. Shelling AN (1997) Role of p53 in drug resistance in ovarian cancer. Lancet 349:744-745
-
(1997)
Lancet
, vol.349
, pp. 744-745
-
-
Shelling, A.N.1
-
77
-
-
9344266882
-
The p53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers
-
77. Hamada M, Fujiwara T, Hizuta A et al (1996) The p53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers. J Cancer Res Clin Oncol 122:360-365
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, pp. 360-365
-
-
Hamada, M.1
Fujiwara, T.2
Hizuta, A.3
-
78
-
-
0029155714
-
Accumulation of p53 protein as a possible predictor of response to adjuvant combination chemotherapy with cyclophosphamide, methotrexate, fluorouracil and prednisone for breast cancer
-
78. Elledge RM, Gray R, Mansour E et al (1995) Accumulation of p53 protein as a possible predictor of response to adjuvant combination chemotherapy with cyclophosphamide, methotrexate, fluorouracil and prednisone for breast cancer. J Natl Cancer Inst 87:1254-1256
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 1254-1256
-
-
Elledge, R.M.1
Gray, R.2
Mansour, E.3
-
79
-
-
0031982783
-
p53 protein accumulation predicts poor response to tamoxifen therapy of patients with recurrent breast cancer
-
79. Berns EMJJ, Klijn JGM, van Putten WLJ et al (1998) p53 protein accumulation predicts poor response to tamoxifen therapy of patients with recurrent breast cancer. J Clin Invest 16:121-127
-
(1998)
J Clin Invest
, vol.16
, pp. 121-127
-
-
Berns, E.M.J.J.1
Klijn, J.G.M.2
Van Putten, W.L.J.3
-
80
-
-
0029956081
-
Specific p53 mutations are associated with de novo resistance to doxorubicine in breast cancer patients
-
80. Aas T, Borresen A-L, Geisler S et al (1996) Specific p53 mutations are associated with de novo resistance to doxorubicine in breast cancer patients. Nature Med 2:811-814
-
(1996)
Nature Med
, vol.2
, pp. 811-814
-
-
Aas, T.1
Borresen, A.-L.2
Geisler, S.3
-
81
-
-
0030992313
-
Expression of p53, glutathione S-transferase-II, and bcl-2 proteins and benefit from adjuvant radiotherapy in breast cancer
-
81. Silvestrini R, Veneroni S, Benini E et al (1997) Expression of p53, glutathione S-transferase-II, and bcl-2 proteins and benefit from adjuvant radiotherapy in breast cancer. J Natl Cancer Inst 89:639-645
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 639-645
-
-
Silvestrini, R.1
Veneroni, S.2
Benini, E.3
-
82
-
-
0032080417
-
Selective sensitivity to radiation of cerebral gioblastomas harboring p53 mutations
-
82. Tada M, Matsumoto R, Iggo RD, Onimaru R, Shirato H, Sawamura Y, Shinohe Y (1998) Selective sensitivity to radiation of cerebral gioblastomas harboring p53 mutations. Cancer Res 58:1793-1797
-
(1998)
Cancer Res
, vol.58
, pp. 1793-1797
-
-
Tada, M.1
Matsumoto, R.2
Iggo, R.D.3
Onimaru, R.4
Shirato, H.5
Sawamura, Y.6
Shinohe, Y.7
-
83
-
-
0030816860
-
Relationship between nitrogen mustard drug resistance in B-CLL and protein expression of bcl-2, bax, bcl-x and p53
-
83. Christodoulopoulos G, Fotouhi N, Krajewski S, Reed JC, Alaoui-Jamali M, Panasci L (1997) Relationship between nitrogen mustard drug resistance in B-CLL and protein expression of bcl-2, bax, bcl-x and p53. Cancer Lett 121:59-67
-
(1997)
Cancer Lett
, vol.121
, pp. 59-67
-
-
Christodoulopoulos, G.1
Fotouhi, N.2
Krajewski, S.3
Reed, J.C.4
Alaoui-Jamali, M.5
Panasci, L.6
-
84
-
-
0032523012
-
Role of p53 in hematopoietic recovery after cytotoxic treatment
-
84. Wlodarski P, Wasik M, Ratajczak MZ et al (1998) Role of p53 in hematopoietic recovery after cytotoxic treatment. Blood 91:2998-3006
-
(1998)
Blood
, vol.91
, pp. 2998-3006
-
-
Wlodarski, P.1
Wasik, M.2
Ratajczak, M.Z.3
-
85
-
-
0032522798
-
Antioxidant action via p53-mediated apoptosis
-
85. Liu M, Pelling JC, Chu E, Brash DE (1998) Antioxidant action via p53-mediated apoptosis. Cancer Res 58:1723-1729
-
(1998)
Cancer Res
, vol.58
, pp. 1723-1729
-
-
Liu, M.1
Pelling, J.C.2
Chu, E.3
Brash, D.E.4
-
86
-
-
0001739436
-
Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the bcl-2-to-bax protein ratio in the cell
-
86. Leri A, Claudio PP, Li Q et al (1998) Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the bcl-2-to-bax protein ratio in the cell. J Clin Invest 101:1326-1342
-
(1998)
J Clin Invest
, vol.101
, pp. 1326-1342
-
-
Leri, A.1
Claudio, P.P.2
Li, Q.3
-
87
-
-
0031892456
-
Acute expression of wt p53 facilitates anticancer drug-induced death of cancer and normal cells
-
87. Blagosklonny MV, ElDeiry WS (1998) Acute expression of wt p53 facilitates anticancer drug-induced death of cancer and normal cells. Int J Cancer 75:933-940
-
(1998)
Int J Cancer
, vol.75
, pp. 933-940
-
-
Blagosklonny, M.V.1
ElDeiry, W.S.2
-
88
-
-
0030781397
-
Novel combination therapy for human colon cancer with adenovirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent
-
88. Ogawa N, Fujiwara T, Kagwa S et al (1997) Novel combination therapy for human colon cancer with adenovirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent. Int J Cancer 73:367-370
-
(1997)
Int J Cancer
, vol.73
, pp. 367-370
-
-
Ogawa, N.1
Fujiwara, T.2
Kagwa, S.3
-
89
-
-
0030787004
-
Adenovirus-mediated p53 gene therapy in nasopharyngeal cancer
-
89. Zeng YX, Prabhu NS, ElDeiry WS (1997) Adenovirus-mediated p53 gene therapy in nasopharyngeal cancer. Int J Oncol 11:221-226
-
(1997)
Int J Oncol
, vol.11
, pp. 221-226
-
-
Zeng, Y.X.1
Prabhu, N.S.2
Eldeiry, W.S.3
-
90
-
-
9544244796
-
Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer
-
90. Roth JA, Nguyen D, Lawrence DD et al (1996) Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nature Med 2:985-991
-
(1996)
Nature Med
, vol.2
, pp. 985-991
-
-
Roth, J.A.1
Nguyen, D.2
Lawrence, D.D.3
-
91
-
-
0030961889
-
Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the c-terminal domain
-
91. Selivanova G, Iotsova V, Okan I et al (1997) Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the c-terminal domain. Nature Med 3:632-638
-
(1997)
Nature Med
, vol.3
, pp. 632-638
-
-
Selivanova, G.1
Iotsova, V.2
Okan, I.3
-
93
-
-
0031905632
-
Accumulation of the p53 protein allows recognition by human CTL of wild type p53 epitope presented by breast carcinomas and melanomas
-
93. Gnjatic S, Gai Z, Viguier M, Chouabi S, Guillet J-G, Choppin J (1998) Accumulation of the p53 protein allows recognition by human CTL of wild type p53 epitope presented by breast carcinomas and melanomas. J Immunol 160:328-333
-
(1998)
J Immunol
, vol.160
, pp. 328-333
-
-
Gnjatic, S.1
Gai, Z.2
Viguier, M.3
Chouabi, S.4
Guillet, J.-G.5
Choppin, J.6
-
94
-
-
0032539816
-
Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation
-
94. Kapoor M, Lozano G (1998) Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation. Proc Natl Acad Sci USA 95:2834-2837
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2834-2837
-
-
Kapoor, M.1
Lozano, G.2
-
95
-
-
0030667702
-
DNA damage-phosphorylation of p53 alleviates inhibition by mdm2
-
95. Shieh SY, Ikeda M, Taya Y, Prives C (1997) DNA damage-phosphorylation of p53 alleviates inhibition by mdm2. Cell 91:325-334
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
|