메뉴 건너뛰기




Volumn 16, Issue 9, 1996, Pages 3019-3025

Chronic 3-nitropropionic acid treatment in baboons replicates the cognitive and motor deficits of Huntington's disease

Author keywords

3 nitropropionic acid; apomorphine testing; baboon; basal ganglia; caudate nucleus; cognitive behavior; frontal cortex; Huntington's disease; motor behavior; object retrieval detour task

Indexed keywords

3 NITROPROPIONIC ACID; APOMORPHINE; CALBINDIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

EID: 0030001887     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-09-03019.1996     Document Type: Article
Times cited : (213)

References (48)
  • 1
    • 0026609559 scopus 로고
    • Alternative excitotoxic hypothesis
    • Albin RL, Greenamyre JT (1992) Alternative excitotoxic hypothesis. Neurology 42:733-738.
    • (1992) Neurology , vol.42 , pp. 733-738
    • Albin, R.L.1    Greenamyre, J.T.2
  • 2
    • 0000876836 scopus 로고
    • Comparison of the effects of frontal and caudate lesions on delayed response and alternation in monkeys
    • Battig K, Rosvold HE, Mishkin M (1960) Comparison of the effects of frontal and caudate lesions on delayed response and alternation in monkeys. J Comp Physiol Psychol 53:400-404.
    • (1960) J Comp Physiol Psychol , vol.53 , pp. 400-404
    • Battig, K.1    Rosvold, H.E.2    Mishkin, M.3
  • 3
    • 0026584524 scopus 로고
    • Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
    • Beal MF (1992) Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann Neurol 31:119-130.
    • (1992) Ann Neurol , vol.31 , pp. 119-130
    • Beal, M.F.1
  • 4
    • 0028077894 scopus 로고
    • Neurochemistry and toxin models in Huntington's disease
    • Beal MF (1994) Neurochemistry and toxin models in Huntington's disease. Curr Opin Neurol 7:542-547.
    • (1994) Curr Opin Neurol , vol.7 , pp. 542-547
    • Beal, M.F.1
  • 6
    • 0028173480 scopus 로고
    • Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate
    • Beal MF, Henshaw R, Jenkins BG, Rosen BR, Schulz JB (1994) Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. Ann Neurol 36:882-888.
    • (1994) Ann Neurol , vol.36 , pp. 882-888
    • Beal, M.F.1    Henshaw, R.2    Jenkins, B.G.3    Rosen, B.R.4    Schulz, J.B.5
  • 8
    • 0023935740 scopus 로고
    • Differential cognitive impairment in Alzheimer's disease and Huntington's disease
    • Brandt J, Folstein SE, Folstein MF (1988) Differential cognitive impairment in Alzheimer's disease and Huntington's disease. Ann Neurol 23:555-561.
    • (1988) Ann Neurol , vol.23 , pp. 555-561
    • Brandt, J.1    Folstein, S.E.2    Folstein, M.F.3
  • 9
    • 0021883670 scopus 로고
    • Regional mitochondrial respiratory activity in Huntington's disease brain
    • Brennan WAJ, Bird ED, Aprille JR (1985) Regional mitochondrial respiratory activity in Huntington's disease brain. J Neurochem 44:1948-1950.
    • (1985) J Neurochem , vol.44 , pp. 1948-1950
    • Waj, B.1    Bird, E.D.2    Aprille, J.R.3
  • 12
    • 0028045985 scopus 로고
    • Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism
    • Brouillet E, Hyman BT, Jenkins BG, Henshaw DR, Schulz JB, Sodhi P, Rosen BR, Beal MF (1994) Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism. Exp Neurol 129:175-182.
    • (1994) Exp Neurol , vol.129 , pp. 175-182
    • Brouillet, E.1    Hyman, B.T.2    Jenkins, B.G.3    Henshaw, D.R.4    Schulz, J.B.5    Sodhi, P.6    Rosen, B.R.7    Beal, M.F.8
  • 13
    • 0017847005 scopus 로고
    • Comparison of the neuropsychological deficits associated with early and advanced Huntington's disease
    • Butters N, Sax D, Montgomery K, Tarlow S (1978) Comparison of the neuropsychological deficits associated with early and advanced Huntington's disease. Arch Neurol 35:585-589.
    • (1978) Arch Neurol , vol.35 , pp. 585-589
    • Butters, N.1    Sax, D.2    Montgomery, K.3    Tarlow, S.4
  • 14
    • 9244229165 scopus 로고
    • Comparison of mnesic performance between humans and baboons with the same automated delayed nonmatching-to-sample task
    • Basel
    • Chavoix C, Dauvillier F, Landeau B, Le Mestric C, Huguet G, Marié RM (1994) Comparison of mnesic performance between humans and baboons with the same automated delayed nonmatching-to-sample task. Folia Primatol (Basel) 62:191-192.
    • (1994) Folia Primatol , vol.62 , pp. 191-192
    • Chavoix, C.1    Dauvillier, F.2    Landeau, B.3    Le Mestric, C.4    Huguet, G.5    Marié, R.M.6
  • 15
    • 0027203627 scopus 로고
    • Frontal-subcortical circuits and human behavior
    • Cummings JL (1993) Frontal-subcortical circuits and human behavior. Arch Neurol 50:873-880.
    • (1993) Arch Neurol , vol.50 , pp. 873-880
    • Cummings, J.L.1
  • 16
    • 0025562947 scopus 로고
    • Developmental time course in human infants and infant monkeys, and the neural bases of inhibitory control in reaching
    • Diamond A (1990) Developmental time course in human infants and infant monkeys, and the neural bases of inhibitory control in reaching. Ann NY Acad Sci 608:637-669.
    • (1990) Ann NY Acad Sci , vol.608 , pp. 637-669
    • Diamond, A.1
  • 17
    • 0000021867 scopus 로고
    • Evidence for involvement of prefrontal cortex in cognitive changes during the first year of life: Comparison of performances of human infant and rhesus monkeys on a detour task with transparent barrier
    • Diamond A, Goldman-Rakic PS (1985) Evidence for involvement of prefrontal cortex in cognitive changes during the first year of life: comparison of performances of human infant and rhesus monkeys on a detour task with transparent barrier. Soc Neurosci Abstr 11:832.
    • (1985) Soc Neurosci Abstr , vol.11 , pp. 832
    • Diamond, A.1    Goldman-Rakic, P.S.2
  • 19
    • 0024380592 scopus 로고
    • Successful performance by monkeys with lesions of the hippocampal formation on AB- and object retrieval, two tasks that mark developmental changes in human infants
    • Diamond A, Zola-Morgan S, Squire LR (1989) Successful performance by monkeys with lesions of the hippocampal formation on AB- and object retrieval, two tasks that mark developmental changes in human infants. Behav Neurosci 103:526-537.
    • (1989) Behav Neurosci , vol.103 , pp. 526-537
    • Diamond, A.1    Zola-Morgan, S.2    Squire, L.R.3
  • 20
    • 0014073057 scopus 로고
    • Behavioral effects of selective ablation of the caudate nucleus
    • Divac J, Rosvold HE, Szwarchart MK (1967) Behavioral effects of selective ablation of the caudate nucleus. J Comp Physiol Psychol 63:184-190.
    • (1967) J Comp Physiol Psychol , vol.63 , pp. 184-190
    • Divac, J.1    Rosvold, H.E.2    Szwarchart, M.K.3
  • 21
    • 0000011555 scopus 로고
    • Striatal pathology of impaired mitochondrial metabolism in primates profiles Huntington's disease
    • Ferrante RJ, Hantraye P, Brouillet E, Kowall NW, Beal MF (1993) Striatal pathology of impaired mitochondrial metabolism in primates profiles Huntington's disease. Soc Neurosci Abstr 19:408.
    • (1993) Soc Neurosci Abstr , vol.19 , pp. 408
    • Ferrante, R.J.1    Hantraye, P.2    Brouillet, E.3    Kowall, N.W.4    Beal, M.F.5
  • 23
    • 0025279038 scopus 로고
    • An experimental primate model of Huntington's disease: Anatomical and behavioural studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon
    • Hantraye P, Riche D, Maziere M, Isacson O (1990) An experimental primate model of Huntington's disease: anatomical and behavioural studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon. Exp Neurol 108:91-104.
    • (1990) Exp Neurol , vol.108 , pp. 91-104
    • Hantraye, P.1    Riche, D.2    Maziere, M.3    Isacson, O.4
  • 24
    • 0026649433 scopus 로고
    • Magnetic resonance imaging to monitor pathology of caudate-putamen after excitotoxin-induced neuronal loss in the non-human primate brain
    • Hantraye P, Leroy-Willig A, Denys A, Riche D, Isacson O, Syrota A (1992a) Magnetic resonance imaging to monitor pathology of caudate-putamen after excitotoxin-induced neuronal loss in the non-human primate brain. Exp Neurol 118:18-23.
    • (1992) Exp Neurol , vol.118 , pp. 18-23
    • Hantraye, P.1    Leroy-Willig, A.2    Denys, A.3    Riche, D.4    Isacson, O.5    Syrota, A.6
  • 25
    • 0026594055 scopus 로고
    • Intrastriatal grafting of fetal striatal cross-species cells ameliorates abnormal movements in a primate model of Huntington's disease
    • Hantraye P, Riche D, Maziere M, Isacson O (1992b) Intrastriatal grafting of fetal striatal cross-species cells ameliorates abnormal movements in a primate model of Huntington's disease. Proc Natl Acad Sci USA 89:4187-4190.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4187-4190
    • Hantraye, P.1    Riche, D.2    Maziere, M.3    Isacson, O.4
  • 26
    • 84889281601 scopus 로고
    • (Harper PS, ed), London: WB Saunders
    • Harper PS (1991) Huntington's disease (Harper PS, ed), pp 1-429. London: WB Saunders.
    • (1991) Huntington's Disease , pp. 1-429
    • Harper, P.S.1
  • 27
    • 9244239898 scopus 로고
    • The relationship between symptoms and functional anatomy in the chronic neurodegenerative diseases: From pharmacological to biological replacement therapy in Huntington's disease
    • (Lindwall O, Bjorklund A, Widner H, eds), Amsterdam: Elsevier Science
    • Isacson O, Hantraye P, Riche D Schumacher JM, Maziere M (1991) The relationship between symptoms and functional anatomy in the chronic neurodegenerative diseases: from pharmacological to biological replacement therapy in Huntington's disease. In: Intracerebral transplantation in movement disorders (Lindwall O, Bjorklund A, Widner H, eds), pp 245-258. Amsterdam: Elsevier Science.
    • (1991) Intracerebral Transplantation in Movement Disorders , pp. 245-258
    • Isacson, O.1    Hantraye, P.2    Riche, D.3    Schumacher, J.M.4    Maziere, M.5
  • 28
    • 0027741301 scopus 로고
    • Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized proton NMR spectroscopy
    • Jenkins BG, Koroshetz WJ, Beal MF, Rosen BR (1993) Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized proton NMR spectroscopy. Neurology 43:2689-2695.
    • (1993) Neurology , vol.43 , pp. 2689-2695
    • Jenkins, B.G.1    Koroshetz, W.J.2    Beal, M.F.3    Rosen, B.R.4
  • 29
    • 0026928944 scopus 로고
    • New insights into the clinical features, pathogenesis and molecular genetics of Huntington's disease
    • Kremer B, Weber B, Hayden MR (1992) New insights into the clinical features, pathogenesis and molecular genetics of Huntington's disease. Brain Pathol 2:321-335.
    • (1992) Brain Pathol , vol.2 , pp. 321-335
    • Kremer, B.1    Weber, B.2    Hayden, M.R.3
  • 30
    • 0019991784 scopus 로고
    • Cerebral metabolism and atrophy in Huntington's disease determined bv 18FDG and computed tomographic scan
    • Kuhl DE, Phelps ME, Markham CH, Metter EJ, Riege WH, Winter J (1982) Cerebral metabolism and atrophy in Huntington's disease determined bv 18FDG and computed tomographic scan. Ann Neurol 12:425-434'
    • (1982) Ann Neurol , vol.12 , pp. 425-434
    • Kuhl, D.E.1    Phelps, M.E.2    Markham, C.H.3    Metter, E.J.4    Riege, W.H.5    Winter, J.6
  • 31
    • 0025153344 scopus 로고
    • Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease
    • Kuwert T, Lange HW, Langen KJ, Herzog H, Aulich A, Feinendegen LE (1990) Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease. Brain 113:1405-1423.
    • (1990) Brain , vol.113 , pp. 1405-1423
    • Kuwert, T.1    Lange, H.W.2    Langen, K.J.3    Herzog, H.4    Aulich, A.5    Feinendegen, L.E.6
  • 32
    • 0026357457 scopus 로고
    • 3-nitropropionic acid: Exogenous animal neurotoxin and possible human striatal toxin
    • Ludolph AC, He F, Spencer PS, Hammerstad J, Sabri M (1991) 3-nitropropionic acid: exogenous animal neurotoxin and possible human striatal toxin. Can J Neurol Sci 18:492-498.
    • (1991) Can J Neurol Sci , vol.18 , pp. 492-498
    • Ludolph, A.C.1    He, F.2    Spencer, P.S.3    Hammerstad, J.4    Sabri, M.5
  • 34
    • 0022876328 scopus 로고
    • Huntington's disease: Pathologenesis and management
    • Martin JB, Gusella J (1986) Huntington's disease: pathologenesis and management. N Engl J Med 315:1267-1276.
    • (1986) N Engl J Med , vol.315 , pp. 1267-1276
    • Martin, J.B.1    Gusella, J.2
  • 36
    • 0025130203 scopus 로고
    • Are all subcortical dementias alike? Verbal learning and memory in Parkinson's and Huntington's disease patients
    • Massman PJ, Delis DC, Butters N, Levin BE, Salmon DP (1990) Are all subcortical dementias alike? Verbal learning and memory in Parkinson's and Huntington's disease patients. J Clin Exp Neuropsychol 12:729-744.
    • (1990) J Clin Exp Neuropsychol , vol.12 , pp. 729-744
    • Massman, P.J.1    Delis, D.C.2    Butters, N.3    Levin, B.E.4    Salmon, D.P.5
  • 38
    • 0024549139 scopus 로고
    • Neurobehavioral changes associated with caudate lesions
    • Mendez MF, Astorna NE, Skoog-Lewandowski K (1989) Neurobehavioral changes associated with caudate lesions. Neurology 39:49-355.
    • (1989) Neurology , vol.39 , pp. 49-355
    • Mendez, M.F.1    Astorna, N.E.2    Skoog-Lewandowski, K.3
  • 39
    • 0025087726 scopus 로고
    • Evidence for a defect in NADH: Ubiquinone oxidoreductase (complex I) in Huntington's disease
    • Parker Jr WD, Boyson SJ, Luder AS, Parks JK (1990) Evidence for a defect in NADH: ubiquinone oxidoreductase (complex I) in Huntington's disease. Neurology 40:1231-1234.
    • (1990) Neurology , vol.40 , pp. 1231-1234
    • Parker Jr., W.D.1    Boyson, S.J.2    Luder, A.S.3    Parks, J.K.4
  • 40
    • 0025755401 scopus 로고
    • Severity and specificity of cognitive impairment in Alzheimer's, Huntington's, and Parkinson's diseases and progressive supranuclear palsy
    • Pillon B, Dubois B, Ploska A, Agid Y (1991) Severity and specificity of cognitive impairment in Alzheimer's, Huntington's, and Parkinson's diseases and progressive supranuclear palsy. Neurology 41:634-643.
    • (1991) Neurology , vol.41 , pp. 634-643
    • Pillon, B.1    Dubois, B.2    Ploska, A.3    Agid, Y.4
  • 41
    • 0025816428 scopus 로고
    • Implicit, explicit, and semantic memory functions in Alzheimer's disease and Huntington's disease
    • Randolph C (1991) Implicit, explicit, and semantic memory functions in Alzheimer's disease and Huntington's disease. J Clin Exp Neuropsychol 13:479-494.
    • (1991) J Clin Exp Neuropsychol , vol.13 , pp. 479-494
    • Randolph, C.1
  • 42
    • 0023584468 scopus 로고
    • Neurological syndrome following bilateral damage to the head of the caudate nuclei
    • Richfield EK, Twyman R, Berent S (1987) Neurological syndrome following bilateral damage to the head of the caudate nuclei. Ann Neurol 22:768-771.
    • (1987) Ann Neurol , vol.22 , pp. 768-771
    • Richfield, E.K.1    Twyman, R.2    Berent, S.3
  • 43
    • 0028255978 scopus 로고
    • 6-hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: Possible interactions with subcortical dopamine
    • Roberts AC, De Salvia MA, Wilkinson LS, Collin P, Muir JL, Everitt BJ, Robbins TW (1994) 6-hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: possible interactions with subcortical dopamine. J Neurosci 14:2531-2544.
    • (1994) J Neurosci , vol.14 , pp. 2531-2544
    • Roberts, A.C.1    De Salvia, M.A.2    Wilkinson, L.S.3    Collin, P.4    Muir, J.L.5    Everitt, B.J.6    Robbins, T.W.7
  • 44
    • 0012062897 scopus 로고
    • Behavioral and neuropathological consequences of chronic exposure to low doses of the dopaminergic neurotoxin MPTP
    • (Isaacson RL, Jensen KF, eds), New York: Plenum
    • Schneider JS (1992) Behavioral and neuropathological consequences of chronic exposure to low doses of the dopaminergic neurotoxin MPTP. In: The vulnerable brain and environmental risks (Isaacson RL, Jensen KF, eds), pp 293-308: New York: Plenum.
    • (1992) The Vulnerable Brain and Environmental Risks , pp. 293-308
    • Schneider, J.S.1
  • 45
    • 0025003032 scopus 로고
    • Improvements in MPTP-induced object retrieval deficits and behavioral deficits after fetal nigral grafting in monkeys
    • Taylor JR, Elsworth JD, Roth RH, Collier TJ, Sladek JR, Redmond DE (1990a) Improvements in MPTP-induced object retrieval deficits and behavioral deficits after fetal nigral grafting in monkeys. Prog Brain Res 62:543-559.
    • (1990) Prog Brain Res , vol.62 , pp. 543-559
    • Taylor, J.R.1    Elsworth, J.D.2    Roth, R.H.3    Collier, T.J.4    Sladek, J.R.5    Redmond, D.E.6
  • 46
    • 0025293227 scopus 로고
    • Cognitive and motor deficits in the acquisition of an object retrieval/ detour task in MPTP-treated monkeys
    • Taylor JR, Redmond JD, Roth RH, Sladek JR, Redmond JR (1990b) Cognitive and motor deficits in the acquisition of an object retrieval/ detour task in MPTP-treated monkeys. Brain 113:617-637.
    • (1990) Brain , vol.113 , pp. 617-637
    • Taylor, J.R.1    Redmond, J.D.2    Roth, R.H.3    Sladek, J.R.4    Redmond, J.R.5
  • 47
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72:971-983.
    • (1993) Cell , vol.72 , pp. 971-983


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.