Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells

Clinical Cancer Research

Volumn 9, Issue 2, 2003, Pages 878-885

  Park, Moon Taek ^a,b   Kang, Jung A ^a   Choi, Jung A ^a   Kang, Chang Mo ^a   Kim, Tae Hwan ^a   Bae, Sangwoo ^a   Kang, Seongman ^b   Kim, Sujong ^c   Choi, Weon Ik ^a   Cho, Chul Koo ^a   Chung, Hee Yong ^c   Lee, Yun Sil ^a   Lee, Su Jae ^a  

^a Korea Cancer Center Hospital   (South Korea)

^b Korea University   (South Korea)

^c Hanyang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE 9; CELL RECEPTOR; CYTOCHROME C; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DNA FRAGMENT; FAS ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHYTOSPHINGOSINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL ASSAY; CELL CYCLE G1 PHASE; CELL DEATH; CELL LEVEL; CELL POPULATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME RELEASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, NON-SMALL-CELL LUNG; CASPASE 8; CASPASE 9; CASPASES; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMANS; LUNG NEOPLASMS; LYMPHOMA, T-CELL; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SPHINGOSINE; TUMOR CELLS, CULTURED;

EID: 0037314856     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

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