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Volumn 9, Issue 1, 2005, Pages 2-9

Iron overload and tuberculosis: A case for iron chelation therapy

Author keywords

Chelation therapy; Iron; Tuberculosis

Indexed keywords

1 AMINO 3 (2 BIPYRIDYL)ISOQUINOLINE DERIVATIVE; 2,3 DIHYDROXYBENZOIC ACID; DEFERASIROX; DEFERIPRONE; DEFEROXAMINE; DEFERRIFERRITHIOCIN; IRON; IRON CHELATING AGENT; ISOQUINOLINE DERIVATIVE; N,N' BIS(2 HYDROXYBENZYL)ETHYLENEDIAMINE N,N' DIACETIC ACID; NORDESFERRITHIOCIN; UNCLASSIFIED DRUG;

EID: 11844268093     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (27)

References (60)
  • 1
    • 0037173578 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of iron homeostasis and toxicity in mammalian cells
    • Chrichton R R, Wilmet S, Legssyer R, Ward R J. Molecular and cellular mechanisms of iron homeostasis and toxicity in mammalian cells. J Inorg Biochem 2002; 91: 9-18.
    • (2002) J Inorg Biochem , vol.91 , pp. 9-18
    • Chrichton, R.R.1    Wilmet, S.2    Legssyer, R.3    Ward, R.J.4
  • 3
    • 0037460114 scopus 로고    scopus 로고
    • The role of iron in infections with intracellular bacteria
    • Collins H F. The role of iron in infections with intracellular bacteria. Immunol Lett 2003; 85: 193-195.
    • (2003) Immunol Lett , vol.85 , pp. 193-195
    • Collins, H.F.1
  • 5
    • 19044389821 scopus 로고    scopus 로고
    • Iron and immunity: A double-edged sword
    • Weiss G. Iron and immunity: a double-edged sword. Eur J Clin Invest 2002; 32: 70-78.
    • (2002) Eur J Clin Invest , vol.32 , pp. 70-78
    • Weiss, G.1
  • 7
    • 0036798949 scopus 로고    scopus 로고
    • African iron overload
    • Gordeuk V R. African iron overload. Semin Hematol 2002; 39: 263-269.
    • (2002) Semin Hematol , vol.39 , pp. 263-269
    • Gordeuk, V.R.1
  • 9
    • 0034235427 scopus 로고    scopus 로고
    • Iron reduction as an adjuvant to interferon therapy in patients with chronic hepatitis C who have previously not responded to interferon: A multicenter, prospective, randomized, controlled trial
    • Di Bisceglie A M, Bonkovsky H L, Chopra S, et al. Iron reduction as an adjuvant to interferon therapy in patients with chronic hepatitis C who have previously not responded to interferon: A multicenter, prospective, randomized, controlled trial. Hepatology 2000; 32: 135-138.
    • (2000) Hepatology , vol.32 , pp. 135-138
    • Di Bisceglie, A.M.1    Bonkovsky, H.L.2    Chopra, S.3
  • 10
    • 0035075181 scopus 로고    scopus 로고
    • Chronic hepatitis C treated with phlebotomy alone: Biochemical and histological outcome
    • Sartori M, Andorno S, Rigamonti C, et al. Chronic hepatitis C treated with phlebotomy alone: biochemical and histological outcome. Dig Liver Dis 2001; 33: 157-162.
    • (2001) Dig Liver Dis , vol.33 , pp. 157-162
    • Sartori, M.1    Andorno, S.2    Rigamonti, C.3
  • 11
    • 0034006433 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 replication in human mononuclear blood cells by the iron chelators deferoxamine, deferiprone, and bleomycin
    • Georgiou N A, van der Bruggen T, Oudshoorn M, Nottet H S L M, Marx J J M, van Asbeck B S. Inhibition of human immunodeficiency virus type 1 replication in human mononuclear blood cells by the iron chelators deferoxamine, deferiprone, and bleomycin. J Infect Dis 2000; 181: 484-490.
    • (2000) J Infect Dis , vol.181 , pp. 484-490
    • Georgiou, N.A.1    Van Der Bruggen, T.2    Oudshoorn, M.3    Nottet, H.S.L.M.4    Marx, J.J.M.5    Van Asbeck, B.S.6
  • 12
    • 0037011071 scopus 로고    scopus 로고
    • Correction of the iron overload defect in β-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis
    • Schaible U E, Collins H L, Priem F, Kaufmann S H E. Correction of the iron overload defect in β-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis. J Exp Med 2002; 196: 1507-1513.
    • (2002) J Exp Med , vol.196 , pp. 1507-1513
    • Schaible, U.E.1    Collins, H.L.2    Priem, F.3    Kaufmann, S.H.E.4
  • 13
    • 0032005180 scopus 로고    scopus 로고
    • Evidence of genetic transmission in African iron overload
    • Moyo V M. Evidence of genetic transmission in African iron overload. Blood 1998; 91: 1076-1082.
    • (1998) Blood , vol.91 , pp. 1076-1082
    • Moyo, V.M.1
  • 14
    • 0032708337 scopus 로고    scopus 로고
    • Iron metabolism and HIV infection: Reciprocal interactions with potentially harmful consequences?
    • Savarino A, Pescarmona G P, Boelaert J R. Iron metabolism and HIV infection: reciprocal interactions with potentially harmful consequences? Cell Biochem Funct 1999; 17: 279-287.
    • (1999) Cell Biochem Funct , vol.17 , pp. 279-287
    • Savarino, A.1    Pescarmona, G.P.2    Boelaert, J.R.3
  • 15
    • 17544404224 scopus 로고    scopus 로고
    • Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity
    • Bogdan C, Röllinghoff M, Diefenbach A. Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity. Curr Opin Immunol 2000; 12: 64-76.
    • (2000) Curr Opin Immunol , vol.12 , pp. 64-76
    • Bogdan, C.1    Röllinghoff, M.2    Diefenbach, A.3
  • 16
    • 0036533562 scopus 로고    scopus 로고
    • Iron chelation via deferoxamine exacerbates experimental Salmonellosis via inhibition of the nicotinamine adenine dinucleotide phosphate oxidase-dependent respiratory burst
    • Collins H F, Kaufmann S H, Schaible U E. Iron chelation via deferoxamine exacerbates experimental Salmonellosis via inhibition of the nicotinamine adenine dinucleotide phosphate oxidase-dependent respiratory burst. J Immunol 2002; 168: 3458-3463.
    • (2002) J Immunol , vol.168 , pp. 3458-3463
    • Collins, H.F.1    Kaufmann, S.H.2    Schaible, U.E.3
  • 17
    • 0034996610 scopus 로고    scopus 로고
    • Advances in the immunopathogenesis of pulmonary tuberculosis
    • Rook G A, Zumla A. Advances in the immunopathogenesis of pulmonary tuberculosis. Curr Opin Pulm Med 2001; 7: 116-123.
    • (2001) Curr Opin Pulm Med , vol.7 , pp. 116-123
    • Rook, G.A.1    Zumla, A.2
  • 18
    • 0032904881 scopus 로고    scopus 로고
    • Therapy by taking away: The case of iron
    • Polla B S. Therapy by taking away: the case of iron. Biochem Pharmacol 1999; 57: 1345-1349.
    • (1999) Biochem Pharmacol , vol.57 , pp. 1345-1349
    • Polla, B.S.1
  • 19
    • 0030869111 scopus 로고    scopus 로고
    • Endothelial cell apoptosis is accelerated by inorganic iron and heat via an oxygen radical dependent mechanism
    • Jacob A K, Hotchkiss R S, DeMeester S L, et al. Endothelial cell apoptosis is accelerated by inorganic iron and heat via an oxygen radical dependent mechanism. Surgery 1997; 122: 243-254.
    • (1997) Surgery , vol.122 , pp. 243-254
    • Jacob, A.K.1    Hotchkiss, R.S.2    DeMeester, S.L.3
  • 20
    • 0030841393 scopus 로고    scopus 로고
    • Iron, infections, and anemia of inflammation
    • Jurado R L. Iron, infections, and anemia of inflammation. Clin Infect Dis 1997; 25: 888-895.
    • (1997) Clin Infect Dis , vol.25 , pp. 888-895
    • Jurado, R.L.1
  • 21
    • 0032830130 scopus 로고    scopus 로고
    • The transferrin receptor: Role in health and disease
    • Ponka P, Lok C N. The transferrin receptor: role in health and disease. Int J Biochem Cell Biol 1999; 31: 1111-1137.
    • (1999) Int J Biochem Cell Biol , vol.31 , pp. 1111-1137
    • Ponka, P.1    Lok, C.N.2
  • 22
    • 0034783452 scopus 로고    scopus 로고
    • Infection with Mycobacterium avium differentially regulates expression of iron transport protein mRNA in murine peritoneal macrophages
    • Zhong W, Lafuse W P, Zwilling B S. Infection with Mycobacterium avium differentially regulates expression of iron transport protein mRNA in murine peritoneal macrophages. Infect Immun 2001; 69: 6618-6624.
    • (2001) Infect Immun , vol.69 , pp. 6618-6624
    • Zhong, W.1    Lafuse, W.P.2    Zwilling, B.S.3
  • 23
    • 0032508046 scopus 로고    scopus 로고
    • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
    • Cole S T, Brosch R, Parkhill J, et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 1998; 393: 537-544.
    • (1998) Nature , vol.393 , pp. 537-544
    • Cole, S.T.1    Brosch, R.2    Parkhill, J.3
  • 25
    • 0037344575 scopus 로고    scopus 로고
    • Mechanisms of iron regulation in mycobacteria: Role in physiology and virulence
    • Rodriguez G M, Smith I. Mechanisms of iron regulation in mycobacteria: role in physiology and virulence. Mol Microbiol 2003; 47: 1485-1494.
    • (2003) Mol Microbiol , vol.47 , pp. 1485-1494
    • Rodriguez, G.M.1    Smith, I.2
  • 27
    • 0033973479 scopus 로고    scopus 로고
    • The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages
    • De Voss J J, Rutter K, Schroeder B G, Su H, Zhu Y, Barry C E III. The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages. Proc Natl Acad Sci U S A 2000; 97: 1252-1257.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1252-1257
    • De Voss, J.J.1    Rutter, K.2    Schroeder, B.G.3    Su, H.4    Zhu, Y.5    Barry III, C.E.6
  • 28
    • 0032167951 scopus 로고    scopus 로고
    • Interdependence of mycobacterial iron regulation, oxidative-stress response and isoniazid resistance
    • Dussurget O, Smith I. Interdependence of mycobacterial iron regulation, oxidative-stress response and isoniazid resistance. Trends Microbiol 1998; 6: 354-358.
    • (1998) Trends Microbiol , vol.6 , pp. 354-358
    • Dussurget, O.1    Smith, I.2
  • 29
    • 0035421993 scopus 로고    scopus 로고
    • Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions
    • Forbes J F, Gros P. Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions. Trends Microbiol 2001; 9: 397-403.
    • (2001) Trends Microbiol , vol.9 , pp. 397-403
    • Forbes, J.F.1    Gros, P.2
  • 30
    • 0031981543 scopus 로고    scopus 로고
    • Metal ion homeostasis and intracellular parasitism
    • Agranoff D D, Krishna S. Metal ion homeostasis and intracellular parasitism. Mol Microbiol 1998; 28: 403-412.
    • (1998) Mol Microbiol , vol.28 , pp. 403-412
    • Agranoff, D.D.1    Krishna, S.2
  • 31
    • 0037154423 scopus 로고    scopus 로고
    • Inactivation of the Mycobacterium tuberculosis Nramp orthologue (mntH) does not affect virulence in a mouse model of tuberculosis
    • Domenech P, Pym A S, Cellier M, Barry III C E, Cole S T. Inactivation of the Mycobacterium tuberculosis Nramp orthologue (mntH) does not affect virulence in a mouse model of tuberculosis. FEMS Microbiol Lett 2002; 207: 81-86.
    • (2002) FEMS Microbiol Lett , vol.207 , pp. 81-86
    • Domenech, P.1    Pym, A.S.2    Cellier, M.3    Barry III, C.E.4    Cole, S.T.5
  • 32
    • 0036081140 scopus 로고    scopus 로고
    • ideR, an essential gene in Mycobacterium tuberculosis: Role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response
    • Rodriguez G M, Voskuil M I, Gold B, Schoolnik G K, Smith I. ideR, an essential gene in Mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect Immun 2002; 70: 3371-3381.
    • (2002) Infect Immun , vol.70 , pp. 3371-3381
    • Rodriguez, G.M.1    Voskuil, M.I.2    Gold, B.3    Schoolnik, G.K.4    Smith, I.5
  • 33
    • 0036077222 scopus 로고    scopus 로고
    • Disruption of the gene homologous to mammalian Nramp1 in Mycobacterium tuberculosis does not affect virulence in mice
    • Boechat N, Lagier-Roger B, Petit S, et al. Disruption of the gene homologous to mammalian Nramp1 in Mycobacterium tuberculosis does not affect virulence in mice. Infect Immun 2002; 70: 4214-4231.
    • (2002) Infect Immun , vol.70 , pp. 4214-4231
    • Boechat, N.1    Lagier-Roger, B.2    Petit, S.3
  • 34
    • 0035013527 scopus 로고    scopus 로고
    • Regulation of catalase-peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis
    • Pym A S, Domenech P, Honore N, Song J, Deretic V, Cole S T. Regulation of catalase-peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis. Mol Microbiol 2001; 40: 879-889.
    • (2001) Mol Microbiol , vol.40 , pp. 879-889
    • Pym, A.S.1    Domenech, P.2    Honore, N.3    Song, J.4    Deretic, V.5    Cole, S.T.6
  • 35
    • 0034976601 scopus 로고    scopus 로고
    • Mapping of Mycobacterium tuberculosis katG promoters and their differential expression in infected macrophages
    • Master S, Zahrt T C, Song J, Deretic V. Mapping of Mycobacterium tuberculosis katG promoters and their differential expression in infected macrophages. J Bacteriol 2001; 183: 4033-4039.
    • (2001) J Bacteriol , vol.183 , pp. 4033-4039
    • Master, S.1    Zahrt, T.C.2    Song, J.3    Deretic, V.4
  • 36
    • 0038054527 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis gene expression in macrophages
    • Dubnau E, Smith I. Mycobacterium tuberculosis gene expression in macrophages. Microbes Infect 2003; 5: 629-637.
    • (2003) Microbes Infect , vol.5 , pp. 629-637
    • Dubnau, E.1    Smith, I.2
  • 37
    • 0032211974 scopus 로고    scopus 로고
    • Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin
    • Quadri L E, Sello J, Keating T A, Weinreb P H, Walsh C T. Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin. Chem Biol 1998; 5: 631-645.
    • (1998) Chem Biol , vol.5 , pp. 631-645
    • Quadri, L.E.1    Sello, J.2    Keating, T.A.3    Weinreb, P.H.4    Walsh, C.T.5
  • 38
    • 0033841813 scopus 로고    scopus 로고
    • Haptoglobin polymorphism and mortality in patients with tuberculosis
    • Kasvosve I, Gomo Z A, Mvundura E, et al. Haptoglobin polymorphism and mortality in patients with tuberculosis. Int J Tuberc Lung Dis 2000; 4: 771-775.
    • (2000) Int J Tuberc Lung Dis , vol.4 , pp. 771-775
    • Kasvosve, I.1    Gomo, Z.A.2    Mvundura, E.3
  • 39
    • 0036066352 scopus 로고    scopus 로고
    • Haptoglobin genotypes are not associated with resistance to severe malaria in The Gambia
    • Aucan C, Walley A J, Greenwoord B M, Hill AVS. Haptoglobin genotypes are not associated with resistance to severe malaria in The Gambia. Trans R Soc Trop Med Hyg 2002; 96: 327-328.
    • (2002) Trans R Soc Trop Med Hyg , vol.96 , pp. 327-328
    • Aucan, C.1    Walley, A.J.2    Greenwoord, B.M.3    Hill, A.V.S.4
  • 40
    • 0033545852 scopus 로고    scopus 로고
    • Transferrin receptor is negatively modulated by the haemochromatosis protein HFE: Implications for cellular iron homeostasis
    • Salter-Cid L, Brunmark A, Li Y, et al. Transferrin receptor is negatively modulated by the haemochromatosis protein HFE: implications for cellular iron homeostasis. Proc Natl Acad Sci USA 1999; 96: 5434-5439.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5434-5439
    • Salter-Cid, L.1    Brunmark, A.2    Li, Y.3
  • 41
    • 0038172355 scopus 로고    scopus 로고
    • Impact of iron loading on the activity of isoniazid or ethambutol in the treatment of murine tuberculosis
    • Lounis N, Maslo C, Truffot-Pernot C, Grosset J, Boelaert R J. Impact of iron loading on the activity of isoniazid or ethambutol in the treatment of murine tuberculosis. Int J Tuberc Lung Dis 2003; 7: 575-579.
    • (2003) Int J Tuberc Lung Dis , vol.7 , pp. 575-579
    • Lounis, N.1    Maslo, C.2    Truffot-Pernot, C.3    Grosset, J.4    Boelaert, R.J.5
  • 42
    • 0027092074 scopus 로고
    • Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection
    • Flynn J L, Goldstein M R, Triebold K J, Koller B, Bloom B R. Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 1992; 89: 12013-12017.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 12013-12017
    • Flynn, J.L.1    Goldstein, M.R.2    Triebold, K.J.3    Koller, B.4    Bloom, B.R.5
  • 44
    • 0035143276 scopus 로고    scopus 로고
    • Role of iron in experimental Mycobacterium avium infection
    • Gomes M S, Boelaert J R, Appelberg A. Role of iron in experimental Mycobacterium avium infection. J Clin Virol 2001; 20: 117-122.
    • (2001) J Clin Virol , vol.20 , pp. 117-122
    • Gomes, M.S.1    Boelaert, J.R.2    Appelberg, A.3
  • 45
    • 0030045401 scopus 로고    scopus 로고
    • Altered iron metabolism in HIV infection: Mechanisms, possible consequences, and proposals for management
    • Boelaert J R, Weinberg G A, Weinberg E D. Altered iron metabolism in HIV infection: mechanisms, possible consequences, and proposals for management. Infect Agents Dis 1996; 5: 36-46.
    • (1996) Infect Agents Dis , vol.5 , pp. 36-46
    • Boelaert, J.R.1    Weinberg, G.A.2    Weinberg, E.D.3
  • 46
    • 0031783138 scopus 로고    scopus 로고
    • Evidence for a link between iron metabolism and Nramp1 gene function in innate resistance against Mycobacterium avium
    • Gomes M S, Appelberg R. Evidence for a link between iron metabolism and Nramp1 gene function in innate resistance against Mycobacterium avium. Immunology 1998; 95: 165-168.
    • (1998) Immunology , vol.95 , pp. 165-168
    • Gomes, M.S.1    Appelberg, R.2
  • 47
    • 0036148173 scopus 로고    scopus 로고
    • Effects on Mycobacterium avium replication in normal human macrophages by deferiprone (L1) and other iron chelators. Possible implications on toxicity
    • Douvas G S, May M H, Kolnagou A, Kontoghiorghes G H. Effects on Mycobacterium avium replication in normal human macrophages by deferiprone (L1) and other iron chelators. Possible implications on toxicity. Arzneimittelforschung 2002; 52: 45-52.
    • (2002) Arzneimittelforschung , vol.52 , pp. 45-52
    • Douvas, G.S.1    May, M.H.2    Kolnagou, A.3    Kontoghiorghes, G.H.4
  • 49
    • 0033693878 scopus 로고    scopus 로고
    • Transfusional iron overload and chelation therapy with deferoxamine and deferiprone (L1)
    • Kontoghiorghes G J, Pattichi K, Hadjigavriel M, Kolnagou A. Transfusional iron overload and chelation therapy with deferoxamine and deferiprone (L1). Transfus Sci 2000; 23: 211-223.
    • (2000) Transfus Sci , vol.23 , pp. 211-223
    • Kontoghiorghes, G.J.1    Pattichi, K.2    Hadjigavriel, M.3    Kolnagou, A.4
  • 50
    • 0036217821 scopus 로고    scopus 로고
    • Natural products as targeted modulators of the nuclear factor-kappaB pathway
    • Bremner P, Heinrich M. Natural products as targeted modulators of the nuclear factor-kappaB pathway. J Pharm Pharmacol 2002; 54: 453-472.
    • (2002) J Pharm Pharmacol , vol.54 , pp. 453-472
    • Bremner, P.1    Heinrich, M.2
  • 51
    • 0028792178 scopus 로고
    • Antioxidant activity of Silybin in vivo during long-term iron overload in rats
    • Pietrangelo A, Borella F, Casalgrandi G, et al. Antioxidant activity of Silybin in vivo during long-term iron overload in rats. Gastroenterology 1995; 109: 1941-1949.
    • (1995) Gastroenterology , vol.109 , pp. 1941-1949
    • Pietrangelo, A.1    Borella, F.2    Casalgrandi, G.3
  • 52
    • 0035676178 scopus 로고    scopus 로고
    • Assessment of antimalarial effect of ICL670A on in vitro cultures of Plasmodium falciparum
    • Goudeau C, Loyevsky M, Kassim O O, et al. Assessment of antimalarial effect of ICL670A on in vitro cultures of Plasmodium falciparum. Br J Haematol 2001; 115: 918-923.
    • (2001) Br J Haematol , vol.115 , pp. 918-923
    • Goudeau, C.1    Loyevsky, M.2    Kassim, O.O.3
  • 53
    • 0035865702 scopus 로고    scopus 로고
    • ICL670A: A new synthetic oral chelator: Evaluation in hypertransfused rats with selective radio iron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells inculture
    • Hershko C, Konijn A M, Nik H P, Breuer W, Cabantchik Z I, Link G. ICL670A: a new synthetic oral chelator: evaluation in hypertransfused rats with selective radio iron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells inculture. Blood 2001; 97: 1115-1122.
    • (2001) Blood , vol.97 , pp. 1115-1122
    • Hershko, C.1    Konijn, A.M.2    Nik, H.P.3    Breuer, W.4    Cabantchik, Z.I.5    Link, G.6
  • 54
    • 0034684207 scopus 로고    scopus 로고
    • The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) and its analogues prevent damage to 2-deoxyribose mediated by ferric iron plus ascorbate
    • Hermes-Lima M, Ponka P, Schulman H M. The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) and its analogues prevent damage to 2-deoxyribose mediated by ferric iron plus ascorbate. Biochim Biophys Acta 2000; 1523: 154-160.
    • (2000) Biochim Biophys Acta , vol.1523 , pp. 154-160
    • Hermes-Lima, M.1    Ponka, P.2    Schulman, H.M.3
  • 55
    • 0034928342 scopus 로고    scopus 로고
    • Exploring the "iron shuttle" hypothesis in chelation therapy: Effects of combined deferoxamine and deferiprone treatment in hypertransfused rats with labelled iron stores and in iron-loaded rat heart cells in culture
    • Link G, Konijn A M, Breuer W, Cabantchik Z I, Hershko C. Exploring the "iron shuttle" hypothesis in chelation therapy: effects of combined deferoxamine and deferiprone treatment in hypertransfused rats with labelled iron stores and in iron-loaded rat heart cells in culture. J Lab Clin Med 2001; 138: 130-138.
    • (2001) J Lab Clin Med , vol.138 , pp. 130-138
    • Link, G.1    Konijn, A.M.2    Breuer, W.3    Cabantchik, Z.I.4    Hershko, C.5
  • 56
    • 0028586693 scopus 로고
    • Control of disease by selective iron depletion: A novel therapeutic strategy utilizing iron chelators
    • Hershko C. Control of disease by selective iron depletion: a novel therapeutic strategy utilizing iron chelators. Baillieres Clin Haematol 1994; 7: 965-1000.
    • (1994) Baillieres Clin Haematol , vol.7 , pp. 965-1000
    • Hershko, C.1
  • 57
    • 0029883690 scopus 로고    scopus 로고
    • Associations of iron overload in Africa with hepatocellular carcinoma and tuberculosis: Strachans's 1929 thesis revisited
    • Gordeuk V R, McLaren C E, Macphail A P, Deichsel G, Bothwell T H. Associations of iron overload in Africa with hepatocellular carcinoma and tuberculosis: Strachans's 1929 thesis revisited. Blood 1996; 87: 3470-3476.
    • (1996) Blood , vol.87 , pp. 3470-3476
    • Gordeuk, V.R.1    McLaren, C.E.2    Macphail, A.P.3    Deichsel, G.4    Bothwell, T.H.5
  • 58
    • 0021340355 scopus 로고
    • Infections in the alcoholic
    • Adams H G, Jordan C. Infections in the alcoholic. Med Clin North Am 1984; 68: 179-200.
    • (1984) Med Clin North Am , vol.68 , pp. 179-200
    • Adams, H.G.1    Jordan, C.2
  • 60
    • 0036433061 scopus 로고    scopus 로고
    • Reactivation of latent tuberculosis by an inhibitor of inducible nitric oxide synthase in an aerosol murine model
    • Botha T, Ryffel B. Reactivation of latent tuberculosis by an inhibitor of inducible nitric oxide synthase in an aerosol murine model. Immunology 2002; 107: 350-357.
    • (2002) Immunology , vol.107 , pp. 350-357
    • Botha, T.1    Ryffel, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.