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Volumn 16, Issue 3, 2003, Pages 139-148

Measurement of dissociation constants of inhibitors binding to Src SH2 domain protein by non-covalent electrospray ionization mass spectrometry

Author keywords

Dissociation constants; Drug discovery; ESI MS; Non covalent complex; Src SH2 domain protein

Indexed keywords


EID: 0038688973     PISSN: 09523499     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmr.622     Document Type: Article
Times cited : (65)

References (21)
  • 1
    • 0032560622 scopus 로고    scopus 로고
    • Probing the "two-pronged plug two-holed socket" model for the mechanism of binding of the Src SH2 domain to phosphotyrosyl peptides: A thermodynamic study
    • Bradshaw JM, Grucza RA, Ladbury JE, Waksman G. 1998. Probing the "two-pronged plug two-holed socket" model for the mechanism of binding of the Src SH2 domain to phosphotyrosyl peptides: a thermodynamic study. Biochemistry 37: 9083-9090.
    • (1998) Biochemistry , vol.37 , pp. 9083-9090
    • Bradshaw, J.M.1    Grucza, R.A.2    Ladbury, J.E.3    Waksman, G.4
  • 2
    • 0032530724 scopus 로고    scopus 로고
    • Mass spectrometric and thermodynamic studies reveal the role of water molecules in complexes formed between SH2 domains and tyrosyl phosphopeptides
    • Chung E, Henriques D, Renzoni D, Zvelebil M, Bradshaw JM, Waksman G, Robinson CV, Ladbury JE. 1998. Mass spectrometric and thermodynamic studies reveal the role of water molecules in complexes formed between SH2 domains and tyrosyl phosphopeptides. Structure 6: 1141-1151.
    • (1998) Structure , vol.6 , pp. 1141-1151
    • Chung, E.1    Henriques, D.2    Renzoni, D.3    Zvelebil, M.4    Bradshaw, J.M.5    Waksman, G.6    Robinson, C.V.7    Ladbury, J.E.8
  • 5
    • 0000876636 scopus 로고
    • Measurement of macromolecular binding using electrospray mass-spectrometry - Determination of dissociation-constants for oligonucleotide-serum albumin complexes
    • Greig MJ, Gaus H, Cummins LI, Sasmor H, Griffey RH. 1995. Measurement of macromolecular binding using electrospray mass-spectrometry - determination of dissociation-constants for oligonucleotide-serum albumin complexes. J. Am. Chem. Soc. 117: 10765-10766.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 10765-10766
    • Greig, M.J.1    Gaus, H.2    Cummins, L.I.3    Sasmor, H.4    Griffey, R.H.5
  • 6
    • 0033025807 scopus 로고    scopus 로고
    • SH2 domains: From structure to energetics, a dual approach to the study of structure-function relationships
    • Grucza RA, Bradshaw JM, Futterer K, Waksman G. 1999. SH2 domains: from structure to energetics, a dual approach to the study of structure-function relationships. Med. Chem. Rev. 19: 273-293.
    • (1999) Med. Chem. Rev. , vol.19 , pp. 273-293
    • Grucza, R.A.1    Bradshaw, J.M.2    Futterer, K.3    Waksman, G.4
  • 7
    • 0032532125 scopus 로고    scopus 로고
    • Direct determination of solution binding constants for noncovalent complexes between bacterial cell wall peptide analogues and vancomycin group antibiotics by electrospray ionization mass spectrometry
    • Jorgensen TJD, Roepstorff P, Heck AJR. 1998. Direct determination of solution binding constants for noncovalent complexes between bacterial cell wall peptide analogues and vancomycin group antibiotics by electrospray ionization mass spectrometry. Anal. Chem. 70: 4427-4432.
    • (1998) Anal. Chem. , vol.70 , pp. 4427-4432
    • Jorgensen, T.J.D.1    Roepstorff, P.2    Heck, A.J.R.3
  • 8
    • 0034331420 scopus 로고    scopus 로고
    • A method for the determination of binding constants by electrospray ionization mass spectrometry
    • Kempen EC, Brodbelt JS. 2000. A method for the determination of binding constants by electrospray ionization mass spectrometry. Anal. Chem. 72: 5411-5416.
    • (2000) Anal. Chem. , vol.72 , pp. 5411-5416
    • Kempen, E.C.1    Brodbelt, J.S.2
  • 9
    • 0032858948 scopus 로고    scopus 로고
    • Protein folding and interactions revealed by mass spectrometry
    • Last AM, Robinson CV. 1999. Protein folding and interactions revealed by mass spectrometry. Curr. Opin. Chem. Biol. 3: 564-570.
    • (1999) Curr. Opin. Chem. Biol. , vol.3 , pp. 564-570
    • Last, A.M.1    Robinson, C.V.2
  • 10
    • 0029035380 scopus 로고
    • Recognition of cellwall peptide ligands by vancomycin group antibiotics - Studies using ion-spray mass-spectrometry
    • Lim HK, Hsieh YI, Ganem B, Henion J. 1995. Recognition of cellwall peptide ligands by vancomycin group antibiotics - studies using ion-spray mass-spectrometry. J. Mass Spectrom. 30: 708-714.
    • (1995) J. Mass Spectrom. , vol.30 , pp. 708-714
    • Lim, H.K.1    Hsieh, Y.I.2    Ganem, B.3    Henion, J.4
  • 11
    • 0034716184 scopus 로고    scopus 로고
    • Electrospray ionisation mass spectrometry: A technology for studying noncovalent macromolecular complexes
    • Loo JA. 2000. Electrospray ionisation mass spectrometry: a technology for studying noncovalent macromolecular complexes. Int J. Mass Spectrom. 200: 175-186.
    • (2000) Int J. Mass Spectrom. , vol.200 , pp. 175-186
    • Loo, J.A.1
  • 12
    • 0031106762 scopus 로고    scopus 로고
    • A study of Src SH2 domain protein-phosphopeptide binding interactions by electrospray ionization mass spectrometry
    • Loo JA, Hu PF, McConnell P, Mueller WT, Sawyer TK, Thanabal V. 1997. A study of Src SH2 domain protein-phosphopeptide binding interactions by electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 8: 234-243.
    • (1997) J. Am. Soc. Mass Spectrom. , vol.8 , pp. 234-243
    • Loo, J.A.1    Hu, P.F.2    McConnell, P.3    Mueller, W.T.4    Sawyer, T.K.5    Thanabal, V.6
  • 15
    • 0034193686 scopus 로고    scopus 로고
    • Measuring dissociation constants of RNA and aminoglycoside antibiotics by electrospray ionization mass spectrometry
    • Sannes-Lowery KA, Griffey RH, Hofstadler SA. 2000. Measuring dissociation constants of RNA and aminoglycoside antibiotics by electrospray ionization mass spectrometry. Anal. Biochem. 280: 264-271.
    • (2000) Anal. Biochem. , vol.280 , pp. 264-271
    • Sannes-Lowery, K.A.1    Griffey, R.H.2    Hofstadler, S.A.3
  • 16
    • 0031917284 scopus 로고    scopus 로고
    • Rapid methods for screening low molecule mass compounds non-covalently bound to proteins using size exclusion and mass spectrometry applied to inhibitors of human cytomegalovirus protease
    • Siegel MM, Tabei K, Bebernitz GA, Baum EZ. 1998. Rapid methods for screening low molecule mass compounds non-covalently bound to proteins using size exclusion and mass spectrometry applied to inhibitors of human cytomegalovirus protease. J. Mass Spectrom. 33: 264-273.
    • (1998) J. Mass Spectrom. , vol.33 , pp. 264-273
    • Siegel, M.M.1    Tabei, K.2    Bebernitz, G.A.3    Baum, E.Z.4
  • 17
    • 0036006578 scopus 로고    scopus 로고
    • Drug screening of pharmaceutical discovery compounds by micro-size exclusion chromatography/mass spectrometry
    • Wabnitz PA, Loo JA. 2002. Drug screening of pharmaceutical discovery compounds by micro-size exclusion chromatography/mass spectrometry. Rapid Commun. Mass Spectrum, 16: 85-91.
    • (2002) Rapid Commun. Mass Spectrum , vol.16 , pp. 85-91
    • Wabnitz, P.A.1    Loo, J.A.2
  • 18
    • 0028936571 scopus 로고
    • An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule
    • Wang Z-X. 1995. An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule. FEBS Lett. 360: 111-114.
    • (1995) FEBS Lett. , vol.360 , pp. 111-114
    • Wang, Z.-X.1
  • 19
    • 0000217562 scopus 로고
    • Electrospray and Taylor-Cone theory, Dole's beam of macromolecules at last?
    • Wilm M, Mann M. 1994. Electrospray and Taylor-Cone theory, Dole's beam of macromolecules at last? Int. J. Mass Spectrom. Ion Process. 136: 167-180.
    • (1994) Int. J. Mass Spectrom. Ion Process. , vol.136 , pp. 167-180
    • Wilm, M.1    Mann, M.2
  • 20
    • 0029685702 scopus 로고    scopus 로고
    • Analytical properties of the nanoelectrospray ion source
    • Wilm M, Mann M. 1996. Analytical properties of the nanoelectrospray ion source. Anal. Chem. 68: 1-8.
    • (1996) Anal. Chem. , vol.68 , pp. 1-8
    • Wilm, M.1    Mann, M.2
  • 21
    • 0031570739 scopus 로고    scopus 로고
    • A high-throughput STAT binding assay using fluorescence polarization
    • Wu PG, Brasseur M, Schindler U. 1997. A high-throughput STAT binding assay using fluorescence polarization. Anal. Biochem. 249: 29-36.
    • (1997) Anal. Biochem. , vol.249 , pp. 29-36
    • Wu, P.G.1    Brasseur, M.2    Schindler, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.