Thermodynamic stability measurements on multimeric proteins using a new H/D exchange- and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry-based method

Protein Science

Volumn 11, Issue 4, 2002, Pages 841-851

  Powell, Kendall D ^a   Wales, Thomas E ^a   Fitzgerald, Michael C ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

H D exchange; MALDI; Protein folding; Thermodynamic stability

Indexed keywords

ALANINE; AMIDE; ASPARTIC ACID; DIMER; ESTER; PROTEIN DERIVATIVE;

ANALYTIC METHOD; ARTICLE; CHEMICAL BOND; ENERGY TRANSFER; GENE MUTATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY; TECHNIQUE; THERMODYNAMICS;

BACTERIAL PROTEINS; DEUTERIUM; DNA-BINDING PROTEINS; ENZYME STABILITY; HYDROGEN; ISOMERASES; MICROCHEMISTRY; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN KINASES; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; THERMODYNAMICS; VIRAL PROTEINS;

EID: 0036127149     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.3820102     Document Type: Article

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