Determination of dissociation constants for protein-ligand complexes by electrospray ionization mass spectrometry

Analytical Chemistry

Volumn 76, Issue 15, 2004, Pages 4325-4331

  Tjernberg, Agneta ^a,b   Carnö, Sofi ^a   Oliv, Frida ^a   Benkestock, Kurt ^a   Edlund, Per Olof ^a   Griffiths, William J ^b,c   Hallén, Dan ^a  

^a BIOVITRUM AB   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CHEMICAL ANALYSIS; CONCENTRATION (PROCESS); ELECTROSTATICS; IONIZATION; MASS SPECTROMETRY; MOLECULAR WEIGHT; PROTEINS;

ELECTROSPRAY IONIZATION MASS SPECTROMETRY (ESI-MS); HUMAN GROWTH HORMONE RECEPTORS; LIGAND SCREENING;

COMPLEXATION;

GROWTH HORMONE RECEPTOR; LIGAND; PROTEIN;

ARTICLE; BIOASSAY; BIOPHYSICS; DISSOCIATION CONSTANT; ELECTRICITY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; MATHEMATICAL ANALYSIS; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ELECTROSTATICS; HUMANS; KINETICS; LIGANDS; MODELS, BIOLOGICAL; PROTEINS; RECEPTORS, SOMATOTROPIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 3543008337     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac0497914     Document Type: Article

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