Major Histocompatibility Complex Class I-presented Antigenic Peptides Are Degraded in Cytosolic Extracts Primarily by Thimet Oligopeptidase

Journal of Biological Chemistry

Volumn 276, Issue 39, 2001, Pages 36474-36481

  Saric, Tomo ^a   Beninga, Jochen ^a,c   Graef, Claudia I ^a,d   Akopian, Tatos N ^a,e   Rock, Kenneth L ^b   Goldberg, Alfred L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^d Knoll AG   (Germany)

^e ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ENZYMES; FRACTIONATION; POLYPEPTIDES;

HISTOCOMPATIBILITY;

ANTIGENS;

1,10 PHENANTHROLINE; AMINO ACID; AMINOPEPTIDASE; ANTIGEN; BESTATIN; EPITOPE; EXOPEPTIDASE; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OVALBUMIN; PHENYLALANYLALANYLPROLYLGLYCYLASPARAGINYLTYROSYLPROLYLALANYLLEUCINE; PROTEASOME; PUROMYCIN; SERYLISOLEUCYLISOLEUCYLASPARAGINYLPHENYLALANYLGLUTAMYLLYSYLLEUCINE; THIMET OLIGOPEPTIDASE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; LEUCINE; METALLOPROTEINASE; PEPTIDE; PROTEIN SYNTHESIS INHIBITOR; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN;

ANTIGEN PRESENTATION; ARTICLE; CATALYSIS; FRACTIONATION; HELA CELL; HUMAN; HUMAN CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PURIFICATION; CHEMISTRY; GENE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOBLOTTING; METABOLISM; PROTEIN TERTIARY STRUCTURE; TIME;

AMINO ACIDS; ANTIGEN PRESENTATION; ANTIGENS; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GENES, MHC CLASS I; HELA CELLS; HUMANS; IMMUNOBLOTTING; INTERFERON TYPE II; LEUCINE; MAJOR HISTOCOMPATIBILITY COMPLEX; METALLOENDOPEPTIDASES; PEPTIDES; PROTEASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PROTEIN SYNTHESIS INHIBITORS; PUROMYCIN; RECOMBINANT PROTEINS; TIME FACTORS;

EID: 0035965357     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105517200     Document Type: Article

References (54)

1. Pamer, E., and Cresswell, P. (1998) Annu. Rev. Immunol. 16, 323-358
2. Rock, K. L., and Goldberg, A. L. (1999) Annu. Rev. Immunol. 17, 739-779
3. Kloetzel, P. M. (2001) Nat. Rev. Mol. Cell Biol. 2, 179-187
4. Yewdell, J. W., and Bennink, J. R. (2001) Cur. Opin. Immunol. 13, 13-18
5. Craiu, A., Gaczynska, M., Akopian, T., Gramm, C. F., Fenteany, G., Goldberg, A. L., and Rock, K. L. (1997) J. Biol. Chem. 272, 13437-13445
6. Cerundolo, V., Benham, A., Braud, V., Mukherjee, S., Gould, K., Macino, B., Neefjes, J., and Townsend, A. (1997) Eur. J. Immunol. 27, 336-341
7. Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., and Goldberg, A. L. (1994) Cell 78, 761-771
8. Michalek, M. T., Grant, E. P., Gramm, C., Goldberg, A. L., and Rock, K. L. (1993) Nature 363, 552-554
9. Grant, E. P., Michalek, M. T., Goldberg, A. L., and Rock, K. L. (1995) J. Immunol. 155, 3750-3758
10. Van den Eynde, B. J., and Morel, S. (2001) Cur. Opin. Immunol. 13, 147-153
11. York, I. A., Goldberg, A. L., Mo, X. Y., and Rock, K. L. (1999) Immunol. Rev. 172, 49-66
12. Kisselev, A. F., Akopian, T. N., and Goldberg, A. L. (1998) J. Biol. Chem. 273, 1982-1989
13. Kisselev, A. F., Akopian, T. N., Woo, K. M., and Goldberg, A. L. (1999) J. Biol. Chem. 274, 3363-3371
14. Falk, K., Rotzschke, O., Stevanovic, S., Jung, G., and Rammensee, H. G. (1991) Nature 351, 290-296
15. Srivastava, P. K., Udono, H., Blachere, N. E., and Li, Z. (1994) Immunogenetics 39, 93-98
16. Paz, P., Brouwenstijn, N., Perry, R., and Shastri, N. (1999) Immunity 11, 241-251
17. Hirsch, C., and Ploegh, H. L. (2000) Trends Cell Biol. 10, 268-272
18. Niedermann, G., Grimm, R., Geier, E., Maurer, M., Realini, C., Gartmann, C., Soll, J., Omura, S., Rechsteiner, M. C., Baumeister, W., and Eichmann, K. (1997) J. Exp. Med. 186, 209-220
19. Lucchiari-Hartz, M., van Endert, P. M., Lauvau, G., Maier, R., Meyerhans, A., Mann, D., Eichmann, K., and Niedermann, G. (2000) J. Exp. Med. 191, 239-252
20. Craiu, A., Akopian, T., Goldberg, A., and Rock, K. L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 10850-10855
21. Beninga, J., Rock, K. L., and Goldberg, A. L. (1998) J. Biol. Chem. 273, 18734-18742
22. Mo, X. Y., Cascio, P., Lemerise, K., Goldberg, A. L., and Rock, K. L. (1999) J. Immunol. 163, 5851-5859
23. Stoltze, L., Schirle, M., Schwarz, G., Schroter, C., Thompson, M. W., Hersh, L., Kalbacher, H., Stevanovich, S., Rammensee, H. G., and Schild, H. (2000) Nat. Immunol. 1, 413-418
24. Cascio, P., Hilton, C., Kisselev, A. F., Rock, K. L., and Goldberg, A. L. (2001) EMBO J. 20, 2357-2366
25. Harris, C. A., Hunte, B., Krauss, M. R., Taylor, A., and Epstein, L. B. (1992) J. Biol. Chem. 267, 6865-6869
26. Barrett, A. J., Brown, M. A., Dando, P. M., Knight, C. G., McKie, N., Rawlings, N. D., and Serizawa, A. (1995) Methods Enzymol. 248, 529-556
27. Crack, P. J., Wu, T. J., Cummins, P. M., Ferro, E. S., Tullai, J. W., Glucksman, M. J., and Roberts, J. L. (1999) Brain Res. 835, 113-124
28. Carvalho, K. M., and Camargo, A. C. M. (1981) Biochemistry 20, 7082-7088
29. Orlowski, M., Michaud, C., and Chu, T. G. (1983) Eur. J. Biochem. 135, 81-88
30. Shrimpton, C. N., and Smith, A. I. (2000) J. Peptide Sci. 6, 251-263
31. Portaro, F. C. V., Gomes, M. D., Cabrera, A., Fernandes, B. L., Silva, C. L., Ferro, E. S., Juliano, L., and Camargo, A. C. M. (1999) Biochem. Biophys. Res. Commun. 255, 596-601
32. Silva, C. L., Portaro, F. C. V., Bonato, V. L. D., Camargo, A. C. M., and Ferro, E. S. (1999) Biochem. Biophys. Res. Commun. 255, 591-595
33. Rammensee, H. G., Friede, T., and Stevanoviic, S. (1995) Immunogenetics 41, 178-228
34. Balow, R. M., Tomkinson, B., Ragnarsson, U., and Zetterqvist, O. (1986) J. Biol. Chem. 261, 2409-2417
35. Macpherson, E., Tomkinson, B., Balow, R. M., Hoglund, S., and Zetterqvist, O. (1987) Biochem. J. 248, 259-263
36. Tomkinson, B. (1999) Trends Biochem. Sci. 24, 355-359
37. Tisljar, U., de Camargo, A. C., da Costa, C. A., and Barrett, A. J. (1989) Biochem. Biophys. Res. Commun. 162, 1460-1464
38. Orlowski, M., Michaud, C., and Molineaux, C. J. (1988) Biochemistry 27, 597-602
39. Chu, T. G., and Orlowski, M. (1984) Biochemistry 23, 3598-3603
40. Jiracek, J., Yiotakis, A., Vincent, B., Lecoq, A., Nicolaou, A., Checler, F., and Dive, V. (1995) J. Biol. Chem. 270, 21701-21706
41. Tisljar, U., Knight, C. G., and Berrett, A. J. (1990) Anal. Biochem. 186, 112-115
42. Massarelli, E. F., Casatti, C. A., Kato, A., Camargo, A. C. M., Bauer, J. A., Glucksman, M. J., Roberts, J. L., Hirose, S., and Ferro, E. S. (1999) Brain Res. 851, 261-265
43. Conn, K. J., Pietropaolo, M., Ju, S. T., and Abraham, C. R. (1996) J. Neurochem. 66, 2011-2018
44. Constam, D. B., Tobler, A. R., Rensing-Ehl, A., Kemler, I., Hersh, L. B., and Fontana, A. (1995) J. Biol. Chem. 270, 26931-26939
45. Polgar, L. (1994) Methods Enzymol. 244, 188-200
46. Johnson, G. D., and Hersh, L. B. (1990) Arch. Biochem. Biophys. 276, 305-309
47. Fruh, K., and Yang, Y. (1999) Cur. Op. Immunol. 11, 76-81
48. Kato, A., Sugiura, N., Saruta, Y., Hosoiri, T., Yasue, H., and Hirose, S. (1997) J. Biol. Chem. 272, 15313-15322
49. Tisljar, U., and Barrett, A. J. (1990) FEBS Lett. 264, 84-86
50. Tisljar, U. (1993) Biol. Chem. Hoppe-Seyler 374, 91-100
51. Boehm, U., Klamp, T., Groot, M., and Howard, J. C. (1997) Annu. Rev. Immunol. 15, 749-795
52. York, I. A., and Rock, K. L. (1996) Annu. Rev. Immunol. 14, 369-396
53. Gaczynska, M., Rock, K. L., and Goldberg, A. L. (1993) Enz. Prot. 47, 354-369
54. Aki, M., Shimbara, N., Takashina, M., Akiyama, K., Kagawa, S., Tamura, T., Tanahashi, N., Yoshimura, T., Tanaka, K., and Ichihara, A. (1994) J. Biochem. (Tokyo) 115, 257-269