Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells

Journal of Experimental Medicine

Volumn 190, Issue 9, 1999, Pages 1227-1239

  Lauvau, Grégoire ^a   Kakimi, Kazuhiro ^b   Niedermann, Gabriele ^c   Ostankovitch, Marina ^d   Yotnda, Patricia ^e   Firat, Hüseyin ^e   Chisari, Francis V ^b   Van Endert, Peter M ^a,f  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^d INSTITUT COCHIN   (France)

^e INSTITUT PASTEUR   (France)

^f INSERM   (France)

Author keywords

ABC transporters; Aminopeptidases; Antigen presentation; HLA class I; Immunodominant epitopes

Indexed keywords

EPITOPE; HLA ANTIGEN CLASS 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; B-LYMPHOCYTES; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CYTOTOXICITY TESTS, IMMUNOLOGIC; ENDOPLASMIC RETICULUM; EPITOPES; HEPACIVIRUS; HEPATITIS B VIRUS; HLA-A2 ANTIGEN; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, KNOCKOUT; PEPTIDES; PROTEIN PRECURSORS; T-LYMPHOCYTES;

EID: 0033230777     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.9.1227     Document Type: Article

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