BACE (β-secretase) modulates the processing of APLP2 in vivo

Molecular and Cellular Neuroscience

Volumn 25, Issue 4, 2004, Pages 642-649

  Pastorino, L ^a   Ikin, A F ^a   Lamprianou, S ^b   Vacaresse, N ^b   Revelli, J P ^c   Platt, K ^c   Paganetti, P ^d   Mathews, P M ^e   Harroch, S ^b   Buxbaum, J D ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b INSTITUT PASTEUR   (France)

^c LEXICON PHARMACEUTICALS INC   (United States)

^d NOVARTIS PHARMA AG   (Switzerland)

^e NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

amyloid peptide; site APP cleaving enzyme; A ; AD; AICD; Alzheimer's disease; Amyloid precursor like protein; Amyloid precursor protein; APLP; APP; BACE; HET; Heterozygous; Knockout; KO; sAPLP2; Soluble APLP2; TG; Transgenic; Wild type; WT

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN LIKE PROTEIN 2; BETA GALACTOSIDASE; BETA SECRETASE; MEMBRANE PROTEIN; PROTEIN HYDROLYSATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL CULTURE; CEREBELLUM; CONTROLLED STUDY; FEMALE; GENE INSERTION; GENE TARGETING; HIPPOCAMPUS; KNOCKOUT MOUSE; MOUSE; NERVE CELL; NONHUMAN; PONS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; SEQUENCE HOMOLOGY; SPINAL CORD; STAINING; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BETA-GALACTOSIDASE; BRAIN; BRAIN CHEMISTRY; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENDOPEPTIDASES; GENES, REPORTER; GENETIC VECTORS; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONS; TRANSFECTION;

INSERTION SEQUENCES; MUS MUSCULUS;

EID: 11144355408     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2003.12.013     Document Type: Article

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