IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL- 18 receptor

Journal of Immunology

Volumn 162, Issue 3, 1999, Pages 1662-1668

  Hyodo, Yasuko ^a   Matsui, Kiyoshi ^a   Hayashi, Nobuki ^a   Tsutsui, Hiroko ^a   Kashiwamura, Shin Ichiro ^a   Yamauchi, Hiroshi ^b   Hiroishi, Keisai ^a   Takeda, Kiyoshi ^a   Tagawa, Yoh Ichi ^c   Iwakura, Yoichiro ^c   Kayagaki, Nobuhiko ^d   Kurimoto, Masashi ^b   Okamura, Haruki ^a   Hada, Toshikazu ^a   Yagita, Hideo ^d   Akira, Shizuo ^a   Nakanishi, Kenji ^a   Higashino, Kazuya ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CONCANAMYCIN A; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 2; INTERLEUKIN RECEPTOR; PERFORIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL ACTIVITY; CYTOTOXICITY; FEMALE; IMMUNOHISTOCHEMISTRY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

ANIMALS; BASE SEQUENCE; CYTOTOXICITY, IMMUNOLOGIC; DNA PRIMERS; FEMALE; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; KILLER CELLS, NATURAL; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, SCID; PORE FORMING CYTOTOXIC PROTEINS; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-12; RECEPTORS, INTERLEUKIN-18; RNA, MESSENGER;

EID: 0033084021     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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