Competition STD NMR for the detection of high-affinity ligands and NMR-based screening

Magnetic Resonance in Chemistry

Volumn 42, Issue 6, 2004, Pages 485-489

  Wang, Yu Sen ^a   Liu, Dingjiang ^a   Wyss, Daniel F ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Competition STD NMR; Dissociation constant determination; High affinity ligands; NMR; NMR based screening

Indexed keywords

CHEMICAL DETECTION; DISSOCIATION; LIGANDS; PROTEINS;

% REDUCTIONS; CHEMICAL EXCHANGE; COMPETITION SATURATION TRANSFER DIFFERENCE NMR; CONSTANT DETERMINATIONS; DISSOCIATION CONSTANT; DISSOCIATION CONSTANT DETERMINATION; HIGH AFFINITY LIGANDS; NMR-BASED SCREENING; SATURATION TRANSFER DIFFERENCES NMR; SATURATION-TRANSFER DIFFERENCES;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ARTICLE; BINDING AFFINITY; LIGAND BINDING; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REDUCTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

EID: 10944256235     PISSN: 07491581     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrc.1381     Document Type: Article

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