Interactions between CBP, NF-κB, and CREB in the lungs after hemorrhage and endotoxemia

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 281, Issue 2 25-2, 2001, Pages

  Shenkar, Robert ^a   Yum, Ho Kee ^a   Arcaroli, John ^a   Kupfner, John ^a   Abraham, Edward ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Acute lung injury; Adenosine 3 5 cyclic monophosphate response element binding protein binding protein; Gene expression regulation; Inflammation; Nuclear factor B; Reactive oxygen species; Transcription factors

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN; PROTEIN C FOS; SYNAPTOTAGMIN; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOTOXEMIA; ENZYME INHIBITION; INFLAMMATION; LUNG; LUNG INJURY; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION;

EID: 0034889412     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.281.2.l418     Document Type: Article

References (39)

1. Activation of extracellular signal-regulated kinases, NF-κB, and cyclic adenosine 5′-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia
2. Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury
3. Role of superoxide in hemorrhagic shock-induced P-selectin expression
4. Hypovolemic shock promotes neutrophil sequestration in lungs by a xanthine oxidase-related mechanism
5. NF-κB: Ten years after
6. The CBP co-activator is a histone acetyltransferase
7. In vivo antioxidant treatment suppresses nuclear factor-κB activation and neutrophilic lung inflammation
8. Interactions between neutrophils and cytokines in blood and alveolar spaces during ARDS
9. Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector function
10. Characterization of monoclonal antibodies raised against p300: Both p300 and CBP are present in intracellular TBP complexes
11. Role of xanthine oxidase and reactive oxygen intermediates in LPS- and TNF-induced pulmonary edema
12. Role of tumour necrosis factor and reactive oxygen intermediates in lipopolysaccharide-induced pulmonary oedema and lethality
13. CREB-binding protein/p300 are transcriptional coactivators of p65
14. Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome
15. Elevated interleukin-1 release by human alveolar macrophages during the adult respiratory distress syndrome
16. Transcription. A growing coactivator network
17. Transcriptional regulation of the transforming growth factor-beta2 promoter by cAMP-responsive element-binding protein (CREB) and activating transcription factor-1 (ATF-1) is modulated by protein kinases and the coactivators p300 and CREB-binding protein
18. The acute respiratory distress syndrome
19. Transcription factor-specific requirements for coactivators and their acetyltransferase functions
20. Nuclear protein CBP is a coactivator for the transcription factor CREB
21. Circadian regulation of cAMP response element-mediated gene expression in the suprachiasmatic nuclei
22. Elevated cyclic AMP inhibits NF-κB-mediated transcription in human monocytic cells and endothelial cells
23. Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism
24. Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-κB-mediated transcription
25. Parathyroid hormone induces c-fos promoter activity in osteoblastic cells through phosphorylated cAMP response element (CRE)-binding protein binding to the major CRE
26. Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway
27. Scientific perspectives on adult respiratory distress syndrome
28. Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome
29. Regulation of immune responses by NF-κB/Rel transcription factor
30. Hemorrhage induces rapid in vivo activation of CREB and NF-κB in murine intraparenchymal lung mononuclear cells
31. Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: Roles of reactive oxygen intermediates, NF-κB, and cyclic AMP response element binding protein
32. Transcriptional activation by NF-κB requires multiple coactivators
33. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis
34. Circulating xanthine oxidase mediates lung neutrophil sequestration after intestinal ischemia-reperfusion
35. Lung injury and complement activation: Role of neutrophils and xanthine oxidase
36. CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p 53 signaling
37. Genomic cloning and promoter analysis of macrophage inflammatory protein (MIP)-2, MIP-1α, and MIP-1β, members of the chemokine superfamily of proinflammatory cytokines
38. Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase
39. Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300