Inhibition of AKT survival pathway by a small molecule inhibitor in human endometrial cancer cells

British Journal of Cancer

Volumn 91, Issue 10, 2004, Pages 1808-1812

  Jin, X ^a   Gossett, D R ^a   Wang, S ^a   Yang, D ^a   Cao, Y ^a   Chen, J ^a   Guo, R ^a   Reynolds, R K ^a   Lin, J ^b  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

AKT; Apoptosis; Endometrial cancer; Experimental therapeutics; PTEN

Indexed keywords

9 METHOXY 2 METHYLELLIPTICINE ACETATE; API 59CJ; APOPTOSIS INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN HEC1A; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN KINASE INHIBITOR; PROTEIN KLE; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME 10; CONTROLLED STUDY; ENDOMETRIUM CANCER; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MOLECULAR BIOLOGY; MUTATOR GENE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PTEN GENE; TUMOR SUPPRESSOR GENE; WILD TYPE;

APOPTOSIS; CELL SURVIVAL; ELLIPTICINES; ENDOMETRIAL NEOPLASMS; ENZYME INHIBITORS; FEMALE; HUMANS; MUTATION; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 10844272299     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602214     Document Type: Article

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