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Archives of Biochemistry and Biophysics

Volumn 433, Issue 2, 2005, Pages 351-360

Modelling atypical CYP3A4 kinetics: Principles and pragmatism

(2) Houston, J Brian a Galetin, Aleksandra a

a UNIVERSITY OF MANCHESTER (United Kingdom)

Author keywords

Atypical kinetics; CYP3A4; Multisite kinetics

Indexed keywords

CYTOCHROME P450 3A4; FELODIPINE; HALOPERIDOL; ITRACONAZOLE; KETOCONAZOLE; MIDAZOLAM; NIFEDIPINE; PROGESTERONE; PYRROLE DERIVATIVE; QUINIDINE; TERFENADINE; TESTOSTERONE;

AREA UNDER THE CURVE; BINDING AFFINITY; BINDING SITE; CELL ISOLATION; CONCENTRATION RESPONSE; CONFERENCE PAPER; DRUG ACTIVATION; DRUG CLEARANCE; DRUG DETERMINATION; DRUG PROTEIN BINDING; ENZYME BLOOD LEVEL; ENZYME STRUCTURE; KINETICS; LIVER CELL; MICHAELIS MENTEN KINETICS; MICROSOME; PRIORITY JOURNAL; STEADY STATE;

ANIMALS; ANTI-ANXIETY AGENTS; AREA UNDER CURVE; BINDING SITES; COMPUTER SIMULATION; CYTOCHROME P-450 ENZYME SYSTEM; DIAZEPAM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME ACTIVATION; HUMANS; KINETICS; MICROSOMES, LIVER; MODELS, CHEMICAL; MODELS, MOLECULAR; SUBSTRATE SPECIFICITY; TESTOSTERONE;

EID: 10044251943 PISSN: 00039861 EISSN: None Source Type: Journal
DOI: 10.1016/j.abb.2004.09.010 Document Type: Conference Paper

Times cited : (89)

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