Human UDP-glucuronosyltransferases: Isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid

Drug Metabolism and Disposition

Volumn 32, Issue 4, 2004, Pages 413-423

  Uchaipichat, Verawan ^a   Mackenzie, Peter I ^a   Guo, Xiao Hui ^a   Gardner Stephen, Dione ^a   Galetin, Aleksandra ^b   Houston, J Brian ^b   Miners, John O ^a,c  

^a FLINDERS UNIVERSITY   (Australia)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c FLINDERS MEDICAL CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

1 NAPHTHOL; ACETONE; ACETONITRILE; ALCOHOL; DICLOFENAC; DIMETHYL SULFOXIDE; GLUCURONOSYLTRANSFERASE; HYMECROMONE; ISOENZYME; METHANOL; ORGANIC SOLVENT; PROBENECID;

ARTICLE; CONCENTRATION RESPONSE; DRUG GLUCURONIDATION; ENZYME INHIBITION; ENZYME SPECIFICITY; HUMAN; MICHAELIS MENTEN KINETICS; PRIORITY JOURNAL; REACTION ANALYSIS; XENOBIOTIC METABOLISM;

ACETONE; ANIMALS; BLOTTING, WESTERN; CACO-2 CELLS; DICLOFENAC; DIMETHYL SULFOXIDE; ETHANOL; GLUCURONATES; GLUCURONOSYLTRANSFERASE; HUMANS; HYMECROMONE; ISOENZYMES; KINETICS; METHANOL; MICE; PROBENECID; SOLVENTS;

EID: 1842536833     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.32.4.413     Document Type: Article

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