The Elusive Role of the Potential Factor X Cation-binding Exosite-1 in Substrate and Inhibitor Interactions

Journal of Biological Chemistry

Volumn 279, Issue 5, 2004, Pages 3671-3679

  Bianchini, Elsa P ^a   Pike, Robert N ^b   Le Bonniec, Bernard F ^a  

^a INSERM   (France)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; ELECTROSTATICS; ENZYMES; SUBSTRATES; TISSUE;

BLOOD CLOTTING;

BIOCHEMISTRY;

ANTITHROMBIN; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; CATION; COMPLEMENTARY DNA; HEPARIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTHROMBIN; THROMBIN; THROMBOCYTE ACTIVATING FACTOR; TISSUE FACTOR PATHWAY INHIBITOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CATION TRANSPORT; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPLEX FORMATION; ELECTRICITY; ENZYME ACTIVATION; ENZYME SUBSTRATE; GENE DISRUPTION; HUMAN; HYDROLYSIS; ION TRANSPORT; KINETICS; METABOLISM; MOLECULAR GENETICS; MOLECULAR RECOGNITION; MUTATION; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; TIME;

AMINO ACID SEQUENCE; ANTITHROMBINS; CATIONS; DNA, COMPLEMENTARY; ELECTROSTATICS; ENZYME ACTIVATION; FACTOR VA; FACTOR X; FACTOR XA; HEPARIN; HUMANS; HYDROLYSIS; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTHROMBIN; THROMBIN; TIME FACTORS;

EID: 0942298106     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309691200     Document Type: Article

References (57)

1. Bode, W., Brandstetter, H., Mather, T., and Stubbs, M. T. (1997) Thromb. Haemostasis 78, 501-511
2. Wu, Q. Y., Sheehan, J. P., Tsiang, M., Lentz, S. R., Birktoft, J. J., and Sadler, J. E. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 6775-6779
3. Sheehan, J. P., and Sadler, J. E. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5518-5522
4. Arni, R. K., Padmanabhan, K., Padmanabhan, K. P., Wu, T. P., and Tulinsky, A. (1993) Biochemistry 32, 4727-4737
5. Dickinson, C. D., Kelly, C. R., and Ruf, W. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14379-14384
6. Dennis, M. S., Eigenbrot, C., Skelton, N. J., Ultsch, M. H., Santel, L., Dwyer, M. A., O'Connell, M., and Lazarus, R. A. (2000) Nature 404, 465-470
7. Kolkman, J. A., Christophe, O. D., Lenting, P. J., and Mertens, K. (1999) J. Biol. Chem. 274, 29087-29093
8. Burgering, M. J., Orbons, L. P., van der Doelen, A., Mulders, J., Theunissen, H. J., Grootenhuis, P. D., Bode, W., Huber, R., and Stubbs, M. T. (1997) J. Mol. Biol. 269, 395-407
9. Mine, S., Yamazaki, T., Miyata, T., Hara, S., and Kato, H. (2002) Biochemistry 41, 78-85
10. Chuang, Y. J., Swanson, R., Raja, S. M., and Olson, S. T. (2001) J. Biol. Chem. 276, 14961-14971
11. Rezaie, A. R. (2000) J. Biol. Chem. 275, 3320-3327
12. Krishnaswamy, S., and Betz, A. (1997) Biochemistry 36, 12080-12086
13. Betz, A., and Krishnaswamy, S. (1998) J. Biol. Chem. 273, 10709-10718
14. Wilkens, M., and Krishnaswamy, S. (2002) J. Biol. Chem. 277, 9366-9374
15. Bianchini, E. P., Louvain, V. B., Marque, P. E., Juliano, M. A., Juliano, L., and Le Bonniec, B. F. (2002) J. Biol. Chem. 277, 20527-20534
16. Picard, V., Marque, P. E., Paolucci, F., Aiach, M., and Le Bonniec, B. F. (1999) J. Biol. Chem. 274, 4586-4593
17. Le Bonniec, B. F., MacGillivray, R. T., and Esmon, C. T. (1991) J. Biol. Chem. 266, 13796-13803
18. Braud, S., Le Bonniec, B. F., Bon, C., and Wisner, A. (2002) Biochemistry 41, 8478-8484
19. Le Bonniec, B. F., Guinto, E. R., and Esmon, C. T. (1992) J. Biol. Chem. 267, 6970-6976
20. Stanley, T. B., Jin, D. Y., Lin, P. J., and Stafford, D. W. (1999) J. Biol. Chem. 274, 16940-16944
21. Camire, R. M., Larson, P. J., Stafford, D. W., and High, K. A. (2000) Biochemistry 39, 14322-14329
22. Jones, D. H., and Howard, B. H. (1990) BioTechniques 8, 178-183
23. Le Bonniec, B. F., Guinto, E. R., MacGillivray, R. T., Stone, S. R., and Esmon, C. T. (1993) J. Biol. Chem. 268, 19055-19061
24. Kosow, D. P., Furie, B., and Forastieri, H. (1974) Thromb. Res. 4, 219-227
25. Drapier, J. C., Tenu, J. P., Lemaire, G., and Petit, J. F. (1979) Biochimie (Paris) 61, 463-471
26. Djie, M. Z., Le Bonniec, B. F., Hopkins, P. C., Hipler, K., and Stone, S. R. (1996) Biochemistry 35, 11461-11469
27. Williams, J. W., and Morrison, J. F. (1979) Methods Enzymol. 63, 437-467
28. Olson, S. T., Bjork, I., and Shore, J. D. (1993) Methods Enzymol. 222, 525-559
29. Laudano, A. P., and Doolittle, R. F. (1980) Biochemistry 19, 1013-1019
30. Rijkers, D. T. S., Wielders, S. J. H., Béguin, S., and Hemker, H. C. (1998) Thromb. Res. 89, 161-169
31. Sabharwal, A. K., Padmanabhan, K., Tulinsky, A., Mathur, A., Gorka, J., and Bajaj, S. P. (1997) J. Biol. Chem. 272, 22037-22045
32. Banner, D. W., D'Arcy, A., Chene, C., Winkler, F. K., Guha, A., Konigsberg, W. H., Nemerson, Y., and Kirchhofer, D. (1996) Nature 380, 41-46
33. Fuentes-Prior, P., Iwanaga, Y., Huber, R., Pagila, R., Rumennik, G., Seto, M., Morser, J., Light, D. R., and Bode, W. (2000) Nature 404, 518-525
34. Shobe, J., Dickinson, C. D., Edgington, T. S., and Ruf, W. (1999) J. Biol. Chem. 274, 24171-24175
35. Mathur, A., Zhong, D., Sabharwal, A. K., Smith, K. J., and Bajaj, S. P. (1997) J. Biol. Chem. 272, 23418-23426
36. Dharmawardana, K. R., and Bock, P. E. (1998) Biochemistry 37, 13143-13152
37. Chen, L., Yang, L., and Rezaie, A. R. (2003) J. Biol. Chem. 278, 27564-27569
38. Anderson, P. J., Nesset, A., Dharmawardana, K. R., and Bock, P. E. (2000) J. Biol. Chem. 275, 16435-16442
39. Stone, S. R., and Hofsteenge, J. (1986) Biochemistry 25, 4622-4628
40. Boskovie, D. S., and Krishnaswamy, S. (2000) J. Biol. Chem. 275, 38561-38570
41. Rezaie, A. R., and Esmon, C. T. (1994) J. Biol. Chem. 269, 21495-21499
42. Rezaie, A. R., and Yang, L. (2001) Biochim. Biophys. Acta 1528, 167-176
43. Bajaj, S. P. (1999) Thromb. Haemostasis 82, 218-225
44. Rudolph, A. E., Porche-Sorbet, R., and Miletich, J. P. (2000) Biochemistry 39, 2861-2867
45. Rudolph, A. E., Porche-Sorbet, R., and Miletich, J. P. (2001) J. Biol. Chem. 276, 5123-5128
46. Kalafatis, M., and Beck, D. O. (2002) Biochemistry 41, 12715-12728
47. Myles, T., Church, F. C., Whinna, H. C., Monard, D., and Stone, S. R. (1998) J. Biol. Chem. 273, 31203-31208
48. Huntington, J. A., Olson, S. T., Fan, B., and Gettins, P. G. (1996) Biochemistry 35, 8495-8503
49. Rezaie, A. R., and Olson, S. T. (2000) Biochemistry 39, 12083-12090
50. Olson, S. T., and Chuang, Y. J. (2002) Trends Cardiovasc. Med. 12, 331-338
51. Yang, L., Manithody, C., and Rezaie, A. R. (2002) J. Biol. Chem. 277, 50756-50760
52. Quinsey, N. S., Whisstock, J. C., Le Bonniec, B., Louvain, V., Bottomley, S. P., and Pike, R. N. (2002) J. Biol. Chem. 277, 15971-15978
53. Manithody, C., Yang, L., and Rezaie, A. R. (2002) Biochemistry 41, 6780-6788
54. Madison, E. L., Goldsmith, E. J., Gerard, R. D., Gething, M. J., and Sambrook, J. F. (1989) Nature 339, 721-724
55. Madison, E. L., Goldsmith, E. J., Gerard, R. D., Gething, M. J., Sambrook, J. F., and Bassel-Duby, R. S. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 3530-3533
56. Horrevoets, A. J., Tans, G., Smilde, A. E., van Zonneveld, A. J., and Pannekoek, H. (1993) J. Biol. Chem. 268, 779-782
57. Dekker, R. J., Eichinger, A., Stoop, A. A., Bode, W., Pannekoek, H., and Horrevoets, A. J. (1999) J. Mol. Biol. 293, 613-627