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Volumn 275, Issue 49, 2000, Pages 38561-38570

Exosite binding tethers the macromolecular substrate to the prothrombinase complex and directs cleavage at two spatially distinct sites

(2) Boskovic, Danilo S a Krishnaswamy, Sriram a,b

a UNIVERSITY OF PENNSYLVANIA (United States)

b CHILDREN S HOSPITAL OF PHILADELPHIA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; PROTEINASE; THROMBIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; COMPETITIVE INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION;

ANIMALS; BINDING SITES; CATTLE; ENDOPEPTIDASES; ENZYME PRECURSORS; FACTOR VA; FACTOR XA; FIBRINOLYTIC AGENTS; KINETICS; MODELS, CHEMICAL; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTHROMBIN; SUBSTRATE SPECIFICITY; THROMBIN; THROMBOPLASTIN;

BOVINAE; RUMEX;

EID: 0034623944 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M006637200 Document Type: Article

Times cited : (38)

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