Definition of a Factor Va Binding Site in Factor Xa

Journal of Biological Chemistry

Volumn 276, Issue 7, 2001, Pages 5123-5128

  Rudolph, Amy E ^a   Porche Sorbet, Rhonda ^c   Miletich, Joseph P ^b  

^a PFIZER INC   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; ENZYMES; MUTAGENESIS; PHOSPHOLIPIDS; SUBSTITUTION REACTIONS;

BINDING AFFINITY;

BIOCHEMISTRY;

ANTITHROMBIN III; ARGININE; BLOOD CLOTTING FACTOR 10 E210N; BLOOD CLOTTING FACTOR 10 K351A; BLOOD CLOTTING FACTOR 10 K414A; BLOOD CLOTTING FACTOR 10 R306A; BLOOD CLOTTING FACTOR 10 R347N; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A WT; BLOOD CLOTTING FACTOR 5A; GLUTAMIC ACID; HEPARIN; LYSINE; PHOSPHOLIPID; PROTHROMBIN; UNCLASSIFIED DRUG; LIPOPROTEIN; LIPOPROTEIN-ASSOCIATED COAGULATION INHIBITOR; THROMBIN; TISSUE FACTOR PATHWAY INHIBITOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MUTAGENESIS; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN BINDING; RADIOASSAY; BINDING COMPETITION; BIOSYNTHESIS; CELL LINE; CHEMICAL STRUCTURE; DRUG ANTAGONISM; GENETICS; METABOLISM; SITE DIRECTED MUTAGENESIS; THROMBOCYTE ACTIVATION;

ANTITHROMBIN III; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; ENZYME ACTIVATION; FACTOR VA; FACTOR XA; HUMANS; LIPOPROTEINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPIDS; PLATELET ACTIVATION; PROTHROMBIN; THROMBIN;

EID: 0035895875     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006961200     Document Type: Article

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